Cheap flights from Greenville to Chicago from $104
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Chicago departing on 11/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Not ready to book? to track prices.United Airlines flights from Greenville to Chicago O'Hare Intl Airport
Our best United Airlines deals on Greenville to Chicago O'Hare Intl Airport flight tickets
Delta flights from Greenville to Chicago O'Hare Intl Airport
Our best Delta deals on Greenville to Chicago O'Hare Intl Airport flight tickets
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Use the filters below to find and compare flights from Greenville to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 10/29
6:08 pm-3:37 pm
1 stop22h 29m
Chicago O'Hare Intl
Sat 11/7
7:35 pm-7:52 pm
2 stops47h 17m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Mon 10/26
8:32 pm-12:51 pm
2 stops17h 19m
Chicago O'Hare Intl
Thu 10/29
8:00 am-8:51 am
1 stop23h 51m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Fri 10/30
2:49 pm-3:37 pm
1 stop25h 48m
Chicago O'Hare Intl
Mon 11/2
7:55 am-8:12 pm
2 stops11h 17m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 10/29
6:01 am-7:22 am
Nonstop2h 21m
Chicago O'Hare Intl
Sun 11/1
6:55 pm-9:59 pm
Nonstop2h 04m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 11/5
11:40 am-1:00 pm
Nonstop2h 20m
Chicago O'Hare Intl
Sun 11/8
8:00 am-11:07 am
Nonstop2h 07m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Wed 12/2
6:30 am-7:46 am
Nonstop2h 16m
Chicago O'Hare Intl
Sat 12/5
6:50 am-9:52 am
Nonstop2h 02m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Wed 11/11
6:20 am-7:36 am
Nonstop2h 16m
Chicago O'Hare Intl
Sat 11/14
1:55 pm-4:56 pm
Nonstop2h 01m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 12/31
6:00 am-7:22 am
Nonstop2h 22m
Chicago O'Hare Intl
Mon 1/4
11:51 am-2:56 pm
Nonstop2h 05m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Fri 3/26
5:40 am-8:34 am
1 stop3h 54m
Chicago O'Hare Intl
Sun 3/28
5:30 am-10:58 am
1 stop4h 28m
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 2/11
6:45 am-10:07 am
1 stop4h 22m
Chicago O'Hare Intl
Mon 2/15
9:30 am-4:09 pm
1 stop5h 39m
See travel insights to Chicago from
How to get the cheapest flight ticket from Greenville to Chicago O'Hare Intl Airport
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Greenville and Chicago O'Hare Intl Airport?
Prices are currently low for flights on this route.
Typical prices usually range from $299 to $471.The lowest price recently found on this route was $283.
What is the cheapest month to fly to Chicago O'Hare Intl Airport?
The month of April is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Greenville averaging around $288.
What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?
The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Saturday when prices can be found for as low as $407. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $681.
What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?
Flying to Chicago O'Hare Intl Airport from Greenville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $338 when looking at flights departing in the evening. Try not to purchase tickets at noon because they tend to be around $698. Of course, these prices can vary depending on the time of year and what airport you fly to.
What is the cheapest Greenville to Chicago O'Hare Intl flight route?
Fly from Greenville to Chicago O'Hare Intl for the best Greenville - Chicago O'Hare Intl flight prices
How far in advance should I book a flight from Greenville to Chicago O'Hare Intl Airport?
You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $325 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Greenville for as low as $156 on momondo.
What cabin class options are available on Greenville to Chicago O'Hare Intl Airport flights?
There are 4 cabin classes available to choose from on Greenville to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from Greenville to Chicago O'Hare Intl?
United Airlines and Delta are the most popular carriers operating from Greenville to Chicago O'Hare Intl
What airlines fly to Chicago O'Hare Intl Airport?
American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Greenville according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 5 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.
How many flights depart from Greenville to Chicago O'Hare Intl Airport on average per day?
The number of flights available between Greenville and Chicago O'Hare Intl Airport is 22 per day as of October 2026. The most frequent departure time is 2:00PM, with 51% of daily flights leaving in the afternoon.
How many flights depart from Greenville to Chicago O'Hare Intl Airport on average per week?
158 flights are operational weekly from Greenville to Chicago O'Hare Intl Airport as of October 2026. The most popular departure day for this route is Fri, with 16% of flights per week taking off on this day.
When to book flights from Greenville to Chicago O'Hare Intl Airport
Cheap Greenville to Chicago O'Hare Intl Airport (GSP to ORD) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Greenville to Chicago O'Hare Intl Airport
Frequently asked questions about flying from Greenville to Chicago O'Hare Intl Airport
How far is Greenville to Chicago O'Hare Intl by plane?
A flight from Greenville to Chicago O'Hare Intl will travel around 575.0 mi. Typically, this will take 2h 02m by plane in normal conditions.
When did momondo last update prices for flights from Greenville Airport to Chicago O'Hare Intl Airport?
Prices for flights from Greenville Airport to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to Chicago O'Hare Intl Airport?
There are 3 operators available for flights from Greenville Airport to Chicago O'Hare Intl Airport as of October 2026.
How old do you have to be to fly from Greenville Airport to Chicago O'Hare Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Greenville to Chicago O'Hare Intl Airport?
Based on momondo bookings for flights between Greenville and Chicago O'Hare Intl Airport, the leading plane model is Embraer 175 (Enhanced Winglets), making up 22.66% of the total bookings. Other popular models include Embraer 175 with 22.57%, Canadair (Bombardier) Regional Jet CRJ-550 with 18.01%, and Embraer 170 with 17.43%.
What is the most popular airline from Greenville to Chicago O'Hare Intl Airport?
momondo data reveals that the most frequently booked airline on the route from Greenville to Chicago O'Hare Intl Airport is American Airlines, representing 55% of all bookings. The subsequent popular airlines are United Airlines at 43% and Delta at 2%.
Best airlines flying from Greenville to Chicago O'Hare Intl Airport
Compare and see reviews for airlines that fly from Greenville to Chicago O'Hare Intl Airport with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $156 | Free Cancellation | Rating 7.8 8,654 reviews | |||
| PriceFrom $209 | Free Cancellation | Rating 7.4 10,332 reviews | |||
| PriceFrom $209 | Free Cancellation | Rating 7.0 12,152 reviews |
United Airlines Flights From Greenville to Chicago O'Hare Intl Airport
United Airlines flight deals from Greenville to Chicago O'Hare Intl Airport start from $209 round-trip. Over the 25 United Airlines flights for this route in a normal week, average airfare is usually $358 round-trip - but some users have found much cheaper deals with momondo.
American Airlines Flights From Greenville to Chicago O'Hare Intl Airport
Another popular option for Greenville to Chicago O'Hare Intl Airport flights is American Airlines (7.0/10, 12,152 ratings). American Airlines flies from Greenville to Chicago O'Hare Intl Airport around 14 times per week, with deals starting from $209 round-trip and rising to an average price of around $309.
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Why should I use momondo to find a flight deal from Greenville to Chicago?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Chicago for you.
Can I find flights from Greenville to Chicago with flexible booking policies on momondo?
All flight searches from Greenville to Chicago on momondo can be filtered to show those which offer flexible booking policies.
How can momondo help me find flights from Greenville to Chicago?
Once you have performed a search for Greenville to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Greenville to Chicago right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of Greenville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.