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Cheap flights from Greenville to Chicago from $88

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Chicago departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:43 pm - 9:17 pm
GSP
-
ORD
28h 34m
1 stop
Multiple Airlines Logo
7:15 pm - 4:53 pm
ORD
-
GSP
20h 38m
1 stop
$209Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
5:43 pm - 11:54 pm
GSP
-
ORD
7h 11m
1 stop
Multiple Airlines Logo
3:05 pm - 4:53 pm
ORD
-
GSP
24h 48m
1 stop
$213Multiple Airlines
Fri, May 1 - Sun, May 10
Multiple Airlines Logo
5:43 pm - 9:17 pm
GSP
-
ORD
28h 34m
1 stop
Multiple Airlines Logo
5:50 am - 4:53 pm
ORD
-
GSP
10h 03m
2 stops
$217Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
Multiple Airlines Logo
4:07 pm - 11:58 pm
GSP
-
ORD
8h 51m
1 stop
Multiple Airlines Logo
5:05 am - 4:53 pm
ORD
-
GSP
10h 48m
1 stop
$224Multiple Airlines
Fri, May 1 - Mon, May 4
Multiple Airlines Logo
5:43 pm - 11:54 pm
GSP
-
ORD
7h 11m
1 stop
Multiple Airlines Logo
5:05 am - 4:53 pm
ORD
-
GSP
10h 48m
1 stop
$225Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
5:43 pm - 9:36 am
GSP
-
ORD
16h 53m
1 stop
Multiple Airlines Logo
2:10 pm - 4:53 pm
ORD
-
GSP
25h 43m
1 stop
$229Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
4:55 pm - 1:14 pm
GSP
-
ORD
21h 19m
1 stop
Multiple Airlines Logo
1:00 pm - 4:53 pm
ORD
-
GSP
26h 53m
1 stop
$233Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
4:55 pm - 1:14 pm
GSP
-
ORD
21h 19m
1 stop
Multiple Airlines Logo
1:00 pm - 4:53 pm
ORD
-
GSP
26h 53m
1 stop
$234Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
5:43 pm - 9:17 pm
GSP
-
ORD
28h 34m
1 stop
Multiple Airlines Logo
5:05 am - 4:53 pm
ORD
-
GSP
10h 48m
1 stop
$236Multiple Airlines
Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
8:18 pm - 11:33 am
GSP
-
ORD
16h 15m
2 stops
Multiple Airlines Logo
2:10 pm - 4:53 pm
ORD
-
GSP
25h 43m
1 stop
$237Multiple Airlines
Fri, Apr 17 - Sun, Apr 19

Southwest flights from Greenville to Chicago O'Hare Intl Airport

Our best Southwest deals on Greenville to Chicago O'Hare Intl Airport flight tickets
Southwest
May 26
GSP6:45 amGreenville
7h 05m
1 stop
ORD12:50 pmChicago O'Hare Intl
May 30
ORD1:55 pmChicago O'Hare Intl
5h 45m
1 stop
GSP8:40 pmGreenville
$275
Southwest
May 26
GSP6:45 amGreenville
7h 05m
1 stop
ORD12:50 pmChicago O'Hare Intl
May 30
ORD1:55 pmChicago O'Hare Intl
7h 00m
2 stops
GSP9:55 pmGreenville
$280
Southwest
May 26
GSP6:45 amGreenville
7h 05m
1 stop
ORD12:50 pmChicago O'Hare Intl
May 29
ORD2:40 pmChicago O'Hare Intl
6h 55m
1 stop
GSP10:35 pmGreenville
$287

Delta flights from Greenville to Chicago O'Hare Intl Airport

Our best Delta deals on Greenville to Chicago O'Hare Intl Airport flight tickets
Delta
May 1
GSP5:23 pmGreenville
5h 02m
1 stop
ORD9:25 pmChicago O'Hare Intl
May 4
ORD5:15 amChicago O'Hare Intl
6h 06m
1 stop
GSP12:21 pmGreenville
$289
Delta
Apr 15
GSP11:35 amGreenville
6h 12m
1 stop
ORD4:47 pmChicago O'Hare Intl
Apr 18
ORD5:15 amChicago O'Hare Intl
5h 58m
1 stop
GSP12:13 pmGreenville
$309
Delta
Apr 11
GSP5:40 amGreenville
3h 50m
1 stop
ORD8:30 amChicago O'Hare Intl
Apr 16
ORD10:45 amChicago O'Hare Intl
6h 34m
1 stop
GSP6:19 pmGreenville
$329

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Greenville to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Mon 4/13

5:43 pm-9:17 pm

1 stop28h 34m

Chicago O'Hare Intl

Thu 4/16

7:15 pm-4:53 pm

1 stop20h 38m

$209

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 5/1

5:43 pm-11:54 pm

1 stop7h 11m

Chicago O'Hare Intl

Sun 5/10

3:05 pm-4:53 pm

1 stop24h 48m

$213

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Mon 4/13

5:43 pm-9:17 pm

1 stop28h 34m

Chicago O'Hare Intl

Mon 4/20

5:50 am-4:53 pm

2 stops10h 03m

$217

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 5/1

4:07 pm-11:58 pm

1 stop8h 51m

Chicago O'Hare Intl

Mon 5/4

5:05 am-4:53 pm

1 stop10h 48m

$224
Quickest round-trip

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 4/24

5:43 pm-11:54 pm

1 stop7h 11m

Chicago O'Hare Intl

Mon 4/27

5:05 am-4:53 pm

1 stop10h 48m

$225

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 4/17

5:43 pm-9:36 am

1 stop16h 53m

Chicago O'Hare Intl

Sun 4/19

2:10 pm-4:53 pm

1 stop25h 43m

$229

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 4/30

4:55 pm-1:14 pm

1 stop21h 19m

Chicago O'Hare Intl

Sun 5/3

1:00 pm-4:53 pm

1 stop26h 53m

$233

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 4/30

4:55 pm-1:14 pm

1 stop21h 19m

Chicago O'Hare Intl

Sun 5/3

1:00 pm-4:53 pm

1 stop26h 53m

$234

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 4/17

5:43 pm-9:17 pm

1 stop28h 34m

Chicago O'Hare Intl

Mon 4/20

5:05 am-4:53 pm

1 stop10h 48m

$236

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 4/17

8:18 pm-11:33 am

2 stops16h 15m

Chicago O'Hare Intl

Sun 4/19

2:10 pm-4:53 pm

1 stop25h 43m

$237

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Greenville to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Chicago O'Hare Intl Airport?

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of March is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Greenville averaging around $260.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $364. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $639.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Greenville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $315 when looking at flights departing in the evening. Try not to purchase tickets at noon because they tend to be around $871. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Greenville to Chicago O'Hare Intl flight route?

Fly from Greenville to Chicago O'Hare Intl for the best Greenville - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $290 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Greenville for as low as $232 on momondo.

What cabin class options are available on Greenville to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Greenville to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Greenville to Chicago O'Hare Intl Airport.

How have Greenville to Chicago O'Hare Intl Airport flight prices changed over time?

As of April 2026, prices for Greenville to Chicago O'Hare Intl Airport flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Chicago O'Hare Intl Airport (GSP to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Chicago O'Hare Intl Airport

Best Price Found

$209

Fastest flight time

2h 02m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Greenville in the past 72 hours is $209. The best round-trip flight deal from Greenville to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $312.
The fastest flight from Greenville to Chicago O'Hare Intl Airport takes 2h 02m
Direct flights go from Greenville to Chicago O'Hare Intl Airport every day.
Search flight deals

Frequently asked questions about flying from Greenville to Chicago O'Hare Intl Airport

  • How far is Greenville to Chicago O'Hare Intl by plane?

    A flight from Greenville to Chicago O'Hare Intl will travel around 575.0 mi. Typically, this will take 2h 02m by plane in normal conditions.

  • When did momondo last update prices for flights from Greenville Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Greenville Airport to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Chicago O'Hare Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Greenville to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Greenville to Chicago O'Hare Intl Airport?

Best airlines flying from Greenville to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Greenville to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $156Free CancellationRating
7.9
8,368 reviews
Search Delta flights
United AirlinesPriceFrom $202Free CancellationRating
7.4
9,529 reviews
Search United Airlines flights
American AirlinesPriceFrom $202Free CancellationRating
7.1
11,544 reviews
Search American Airlines flights

  • United Airlines Flights From Greenville to Chicago O'Hare Intl Airport

    United Airlines flight deals from Greenville to Chicago O'Hare Intl Airport start from $202 round-trip. Over the 23 United Airlines flights for this route in a normal week, average airfare is usually $307 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Greenville to Chicago O'Hare Intl Airport

    Another popular option for Greenville to Chicago O'Hare Intl Airport flights is American Airlines (7.1/10, 11,544 ratings). American Airlines flies from Greenville to Chicago O'Hare Intl Airport around 8 times per week, with deals starting from $202 round-trip and rising to an average price of around $287.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Schaumburg
South Haven
Rockford
Merrillville
Gurnee
Rosemont
Naperville
New Buffalo
Orland Park
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Joliet
Janesville
Aurora
Racine
Hammond
Elgin
Tinley Park
South Holland

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Chicago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Chicago for you.

Can I find flights from Greenville to Chicago with flexible booking policies on momondo?

All flight searches from Greenville to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to Chicago?

Once you have performed a search for Greenville to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Greenville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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