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Cheap flights from Greenville to Chicago from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Chicago departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:10 am - 7:30 am
GSP
-
ORD
2h 20mnonstop
United Airlines Logo
6:10 pm - 9:17 pm
ORD
-
GSP
2h 07mnonstop
$262United Airlines
Sat, Jul 4 - Mon, Jul 6
American Airlines Logo
6:43 pm - 8:14 pm
GSP
-
ORD
2h 31mnonstop
American Airlines Logo
8:59 pm - 11:58 pm
ORD
-
GSP
1h 59mnonstop
$263American Airlines
Fri, Jul 3 - Sun, Jul 5
Multiple Airlines Logo
12:06 pm - 7:53 am
GSP
-
ORD
20h 47m
2 stops
Multiple Airlines Logo
8:05 am - 7:57 am
ORD
-
GSP
22h 52m
1 stop
$268Multiple Airlines
Mon, Jul 13 - Sat, Jul 18
United Airlines Logo
6:10 am - 7:29 am
GSP
-
ORD
2h 19mnonstop
United Airlines Logo
6:10 pm - 9:17 pm
ORD
-
GSP
2h 07mnonstop
$269United Airlines
Wed, Jun 24 - Fri, Jul 3
American Airlines Logo
6:18 pm - 10:00 pm
GSP
-
ORD
4h 42m
1 stop
American Airlines Logo
8:59 pm - 11:58 pm
ORD
-
GSP
1h 59mnonstop
$271American Airlines
Fri, Jul 3 - Sun, Jul 5
American Airlines Logo
7:00 am - 12:19 pm
GSP
-
ORD
6h 19m
1 stop
American Airlines Logo
8:59 pm - 11:58 pm
ORD
-
GSP
1h 59mnonstop
$272American Airlines
Sat, Jul 4 - Mon, Jul 6
Delta Logo
5:16 pm - 8:32 pm
GSP
-
ORD
4h 16m
1 stop
Delta Logo
7:01 am - 12:06 pm
ORD
-
GSP
4h 05m
1 stop
$275Delta
Fri, Jul 3 - Sat, Jul 4
United Airlines Logo
7:40 pm - 11:26 pm
GSP
-
ORD
4h 46m
1 stop
United Airlines Logo
6:10 pm - 9:17 pm
ORD
-
GSP
2h 07mnonstop
$279United Airlines
Wed, Jun 24 - Fri, Jul 3
United Airlines Logo
6:10 am - 7:29 am
GSP
-
ORD
2h 19mnonstop
United Airlines Logo
6:55 am - 9:55 am
ORD
-
GSP
2h 00mnonstop
$281United Airlines
Sun, Jun 14 - Sun, Jun 21
Delta Logo
7:42 pm - 11:59 pm
GSP
-
ORD
5h 17m
1 stop
Delta Logo
2:00 pm - 9:38 pm
ORD
-
GSP
6h 38m
1 stop
$282Delta
Thu, May 28 - Thu, Jun 4

American Airlines flights from Greenville to Chicago O'Hare Intl Airport

Our best American Airlines deals on Greenville to Chicago O'Hare Intl Airport flight tickets
American Airlines
May 28
GSP7:20 amGreenville
2h 27m
ORD8:47 amChicago O'Hare Intl
Jun 6
ORD3:05 pmChicago O'Hare Intl
2h 01m
GSP6:06 pmGreenville
$262
American Airlines
Jul 3
GSP6:43 pmGreenville
2h 31m
ORD8:14 pmChicago O'Hare Intl
Jul 5
ORD8:59 pmChicago O'Hare Intl
1h 59m
GSP11:58 pmGreenville
$263
American Airlines
Jun 24
GSP7:20 amGreenville
2h 26m
ORD8:46 amChicago O'Hare Intl
Jun 29
ORD8:00 amChicago O'Hare Intl
2h 03m
GSP11:03 amGreenville
$269

United Airlines flights from Greenville to Chicago O'Hare Intl Airport

Our best United Airlines deals on Greenville to Chicago O'Hare Intl Airport flight tickets
United Airlines
Jul 4
GSP6:10 amGreenville
2h 20m
ORD7:30 amChicago O'Hare Intl
Jul 6
ORD6:10 pmChicago O'Hare Intl
2h 07m
GSP9:17 pmGreenville
$262
United Airlines
Jun 14
GSP6:10 amGreenville
2h 19m
ORD7:29 amChicago O'Hare Intl
Jun 21
ORD6:55 amChicago O'Hare Intl
2h 00m
GSP9:55 amGreenville
$281
United Airlines
Jun 16
GSP7:40 pmGreenville
4h 46m
1 stop
ORD11:26 pmChicago O'Hare Intl
Jun 17
ORD6:55 amChicago O'Hare Intl
2h 00m
GSP9:55 amGreenville
$285

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Greenville to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sat 7/4

6:10 am-7:30 am

Nonstop2h 20m

Chicago O'Hare Intl

Mon 7/6

6:10 pm-9:17 pm

Nonstop2h 07m

$262

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 7/3

6:43 pm-8:14 pm

Nonstop2h 31m

Chicago O'Hare Intl

Sun 7/5

8:59 pm-11:58 pm

Nonstop1h 59m

$263

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Mon 7/13

12:06 pm-7:53 am

2 stops20h 47m

Chicago O'Hare Intl

Sat 7/18

8:05 am-7:57 am

1 stop22h 52m

$268

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Wed 6/24

6:10 am-7:29 am

Nonstop2h 19m

Chicago O'Hare Intl

Fri 7/3

6:10 pm-9:17 pm

Nonstop2h 07m

$269

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 7/3

6:18 pm-10:00 pm

1 stop4h 42m

Chicago O'Hare Intl

Sun 7/5

8:59 pm-11:58 pm

Nonstop1h 59m

$271

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sat 7/4

7:00 am-12:19 pm

1 stop6h 19m

Chicago O'Hare Intl

Mon 7/6

8:59 pm-11:58 pm

Nonstop1h 59m

$272

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 7/3

5:16 pm-8:32 pm

1 stop4h 16m

Chicago O'Hare Intl

Sat 7/4

7:01 am-12:06 pm

1 stop4h 05m

$275

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Wed 6/24

7:40 pm-11:26 pm

1 stop4h 46m

Chicago O'Hare Intl

Fri 7/3

6:10 pm-9:17 pm

Nonstop2h 07m

$279
Quickest round-trip

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sun 6/14

6:10 am-7:29 am

Nonstop2h 19m

Chicago O'Hare Intl

Sun 6/21

6:55 am-9:55 am

Nonstop2h 00m

$281

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 5/28

7:42 pm-11:59 pm

1 stop5h 17m

Chicago O'Hare Intl

Thu 6/4

2:00 pm-9:38 pm

1 stop6h 38m

$282

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Greenville to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Chicago O'Hare Intl Airport?

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of December is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Greenville averaging around $276.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $377. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $653.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Greenville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $320 when looking at flights departing in the evening. Try not to purchase tickets at noon because they tend to be around $914. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Greenville to Chicago O'Hare Intl flight route?

Fly from Greenville to Chicago O'Hare Intl for the best Greenville - Chicago O'Hare Intl flight prices

How far in advance should I book a flight from Greenville to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $298 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Greenville for as low as $179 on momondo.

Can stopping save me money on Greenville to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Greenville to Chicago O'Hare Intl Airport.

How have Greenville to Chicago O'Hare Intl Airport flight prices changed over time?

As of May 2026, prices for Greenville to Chicago O'Hare Intl Airport flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Chicago O'Hare Intl Airport (GSP to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Chicago O'Hare Intl Airport

Best Price Found

$253

Fastest flight time

2h 02m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Greenville in the past 72 hours is $253. The best round-trip flight deal from Greenville to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $372.
The fastest flight from Greenville to Chicago O'Hare Intl Airport takes 2h 02m
Direct flights go from Greenville to Chicago O'Hare Intl Airport every day.
Search flight deals

Frequently asked questions about flying from Greenville to Chicago O'Hare Intl Airport

  • How far is Greenville to Chicago O'Hare Intl by plane?

    A flight from Greenville to Chicago O'Hare Intl will travel around 575.0 mi. Typically, this will take 2h 02m by plane in normal conditions.

  • When did momondo last update prices for flights from Greenville Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Greenville Airport to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Chicago O'Hare Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Greenville to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Greenville to Chicago O'Hare Intl Airport?

Best airlines flying from Greenville to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Greenville to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $107Free CancellationRating
7.9
8,447 reviews
Search Delta flights
United AirlinesPriceFrom $202Free CancellationRating
7.4
9,737 reviews
Search United Airlines flights
American AirlinesPriceFrom $202Free CancellationRating
7.1
11,648 reviews
Search American Airlines flights

  • United Airlines Flights From Greenville to Chicago O'Hare Intl Airport

    United Airlines flight deals from Greenville to Chicago O'Hare Intl Airport start from $202 round-trip. Over the 22 United Airlines flights for this route in a normal week, average airfare is usually $314 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Greenville to Chicago O'Hare Intl Airport

    Another popular option for Greenville to Chicago O'Hare Intl Airport flights is American Airlines (7.1/10, 11,648 ratings). American Airlines flies from Greenville to Chicago O'Hare Intl Airport around 17 times per week, with deals starting from $202 round-trip and rising to an average price of around $289.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Rosemont
Naperville
Orland Park
New Buffalo
Oak Brook
Kenosha
Joliet
Aurora
Racine
Janesville
Hammond
Evanston
Elgin
Tinley Park

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Chicago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Chicago for you.

Can I find flights from Greenville to Chicago with flexible booking policies on momondo?

All flight searches from Greenville to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to Chicago?

Once you have performed a search for Greenville to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Greenville to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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