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Cheap flights from Greenville to the Cayman Islands from $605

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to the Cayman Islands departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to the Cayman Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:45 am - 11:41 am
GSP
-
GCM
5h 56m
1 stop
Delta Logo
12:56 pm - 9:25 pm
GCM
-
GSP
7h 29m
1 stop
$605Delta
Tue, Aug 25 - Tue, Sep 1
American Airlines Logo
7:16 pm - 11:10 am
GSP
-
GCM
16h 54m
2 stops
American Airlines Logo
2:10 pm - 10:37 am
GCM
-
GSP
19h 27m
2 stops
$610American Airlines
Tue, Aug 25 - Tue, Sep 1
American Airlines Logo
5:20 am - 11:31 am
GSP
-
GCM
7h 11m
1 stop
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
GSP
5h 47m
1 stop
$682American Airlines
Mon, May 18 - Mon, May 25
American Airlines Logo
5:20 am - 11:31 am
GSP
-
GCM
7h 11m
1 stop
American Airlines Logo
5:12 pm - 2:07 pm
GCM
-
GSP
19h 55m
2 stops
$687American Airlines
Mon, May 18 - Mon, May 25
Delta Logo
5:40 am - 11:54 am
GSP
-
GCM
7h 14m
1 stop
Delta Logo
1:19 pm - 11:43 pm
GCM
-
GSP
9h 24m
1 stop
$692Delta
Thu, May 28 - Sun, May 31
American Airlines Logo
5:21 am - 11:30 am
GSP
-
GCM
7h 09m
1 stop
American Airlines Logo
5:11 pm - 12:10 pm
GCM
-
GSP
17h 59m
2 stops
$702American Airlines
Thu, May 28 - Sun, May 31
American Airlines Logo
8:02 am - 3:03 pm
GSP
-
GCM
8h 01m
1 stop
American Airlines Logo
11:55 am - 11:59 pm
GCM
-
GSP
11h 04m
1 stop
$707American Airlines
Sat, May 16 - Sat, May 23
American Airlines Logo
5:20 am - 1:10 pm
GSP
-
GCM
8h 50m
2 stops
American Airlines Logo
12:31 pm - 11:52 pm
GCM
-
GSP
10h 21m
1 stop
$712American Airlines
Sat, May 16 - Sat, May 23
American Airlines Logo
7:02 am - 11:31 am
GSP
-
GCM
5h 29m
1 stop
American Airlines Logo
5:12 pm - 8:18 am
GCM
-
GSP
14h 06m
2 stops
$717American Airlines
Wed, May 20 - Wed, May 27
Delta Logo
5:40 am - 11:54 am
GSP
-
GCM
7h 14m
1 stop
Delta Logo
1:19 pm - 8:13 pm
GCM
-
GSP
5h 54m
1 stop
$721Delta
Sat, May 16 - Sat, May 23

Delta flights from Greenville to Cayman Islands

Our best Delta deals on Greenville to Cayman Islands flight tickets
Delta
Aug 25
GSP6:45 amGreenville
5h 56m
1 stop
GCM11:41 amGeorge Town Owen Roberts Intl
Sep 1
GCM12:56 pmGeorge Town Owen Roberts Intl
7h 29m
1 stop
GSP9:25 pmGreenville
$605
Delta
May 28
GSP5:40 amGreenville
7h 14m
1 stop
GCM11:54 amGeorge Town Owen Roberts Intl
May 31
GCM1:19 pmGeorge Town Owen Roberts Intl
9h 24m
1 stop
GSP11:43 pmGreenville
$692
Delta
May 16
GSP5:40 amGreenville
7h 14m
1 stop
GCM11:54 amGeorge Town Owen Roberts Intl
May 23
GCM1:19 pmGeorge Town Owen Roberts Intl
5h 54m
1 stop
GSP8:13 pmGreenville
$721

American Airlines flights from Greenville to Cayman Islands

Our best American Airlines deals on Greenville to Cayman Islands flight tickets
American Airlines
Aug 25
GSP7:16 pmGreenville
16h 54m
2 stops
GCM11:10 amGeorge Town Owen Roberts Intl
Sep 1
GCM2:10 pmGeorge Town Owen Roberts Intl
19h 27m
2 stops
GSP10:37 amGreenville
$610
American Airlines
May 18
GSP5:20 amGreenville
7h 11m
1 stop
GCM11:31 amGeorge Town Owen Roberts Intl
May 25
GCM5:12 pmGeorge Town Owen Roberts Intl
5h 47m
1 stop
GSP11:59 pmGreenville
$682
American Airlines
May 18
GSP5:20 amGreenville
7h 11m
1 stop
GCM11:31 amGeorge Town Owen Roberts Intl
May 25
GCM5:12 pmGeorge Town Owen Roberts Intl
19h 55m
2 stops
GSP2:07 pmGreenville
$687

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Greenville to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Tue 8/25

6:45 am-11:41 am

1 stop5h 56m

George Town Owen Roberts Intl

Tue 9/1

12:56 pm-9:25 pm

1 stop7h 29m

$605

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Tue 8/25

7:16 pm-11:10 am

2 stops16h 54m

George Town Owen Roberts Intl

Tue 9/1

2:10 pm-10:37 am

2 stops19h 27m

$610
Quickest round-trip

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Mon 5/18

5:20 am-11:31 am

1 stop7h 11m

George Town Owen Roberts Intl

Mon 5/25

5:12 pm-11:59 pm

1 stop5h 47m

$682

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Mon 5/18

5:20 am-11:31 am

1 stop7h 11m

George Town Owen Roberts Intl

Mon 5/25

5:12 pm-2:07 pm

2 stops19h 55m

$687

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/28

5:40 am-11:54 am

1 stop7h 14m

George Town Owen Roberts Intl

Sun 5/31

1:19 pm-11:43 pm

1 stop9h 24m

$692

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/28

5:21 am-11:30 am

1 stop7h 09m

George Town Owen Roberts Intl

Sun 5/31

5:11 pm-12:10 pm

2 stops17h 59m

$702

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 5/16

8:02 am-3:03 pm

1 stop8h 01m

George Town Owen Roberts Intl

Sat 5/23

11:55 am-11:59 pm

1 stop11h 04m

$707

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 5/16

5:20 am-1:10 pm

2 stops8h 50m

George Town Owen Roberts Intl

Sat 5/23

12:31 pm-11:52 pm

1 stop10h 21m

$712

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Wed 5/20

7:02 am-11:31 am

1 stop5h 29m

George Town Owen Roberts Intl

Wed 5/27

5:12 pm-8:18 am

2 stops14h 06m

$717

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 5/16

5:40 am-11:54 am

1 stop7h 14m

George Town Owen Roberts Intl

Sat 5/23

1:19 pm-8:13 pm

1 stop5h 54m

$721

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Cheap Greenville to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Cayman Islands

Fastest flight time

6h 56m

Direct flights

None
The fastest flight from Greenville to Cayman Islands takes 6h 56m
There are no direct flights from Greenville to Cayman Islands. There are no popular flight routes from Greenville to Cayman Islands.
Search flight deals

Frequently asked questions about flying from Greenville to the Cayman Islands

  • When did momondo last update prices for flights from Greenville Airport to Cayman Islands?

    Prices for flights from Greenville Airport to Cayman Islands were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Cayman Islands?

  • How old do you have to be to fly from Greenville Airport to Cayman Islands?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Cayman Islands.

  • What documentation or ID do you need to fly to Cayman Islands?

    The necessary travel and health documents for your Cayman Islands trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Greenville to Cayman Islands

Compare and see reviews for airlines that fly from Greenville to Cayman Islands with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $374Free CancellationRating
7.1
11,548 reviews
Search American Airlines flights

Frequently asked questions about flying from Greenville to the Cayman Islands

  • How do I get Price Alerts for flights from Greenville to Cayman Islands?

    Confirm your travel details to search for the latest offers for flights from Greenville to Cayman Islands. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Greenville to Cayman Islands with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Cayman Islands?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Cayman Islands for you.

Can I find flights from Greenville to Cayman Islands with flexible booking policies on momondo?

Yes. All flights to Cayman Islands from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Cayman Islands?

momondo provides multiple filters to help you find the best flight to Cayman Islands from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to Cayman Islands right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Cayman Islands, momondo offers a useful price alert feature which will track prices for flights to Cayman Islands from Greenville and alert you when they change.

An easier way to manage your Cayman Islands trip

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Find better results for your trip to the Cayman Islands

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