Cheap flights from Florida to Panama City from $176

In general, April is the cheapest month to fly from Florida to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $402. If you’re not able to fly to Panama City in April, then March is your next best option. Flight prices from Florida to Panama City during March average around $436.

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $501. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $570. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Florida to Panama City during this time can be as low as $511. Try not to purchase tickets in the morning because they tend to be around $552. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Miami to Panama City Tocumen Intl for the best Florida - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Florida when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $563 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Florida for as low as $489 on momondo.

There are 3 cabin classes available to choose from on Florida to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

United Airlines, Copa Airlines, and American Airlines are the most popular carriers operating from Florida to Panama City Tocumen Intl

Copa Airlines, American Airlines and Avianca are the top three most popular airlines that fly to Panama City from Florida according to our data. Copa Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 6 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

As of September 2026, there are 26 flights per day flying from Florida to Panama City. The most common time of day flights depart is 5:00PM, with 51% of flights taking off in the afternoon.

185 flights are operational weekly from Florida to Panama City as of September 2026. The most popular departure day for this route is Fri, with 17% of flights per week taking off on this day.