When did momondo last update prices for flights from Des Moines Airport to Panama?

Prices for flights from Des Moines Airport to Panama were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Panama?

As of September 2026, there is 1 operator available to choose from for flights from Des Moines Airport to Panama.

How old do you have to be to fly from Des Moines Airport to Panama?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$607 Cheap Flights from Des Moines to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Panama

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 7:38 pmDSM Des Moines-PTY Panama City Tocumen Intl

10h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

14h 35m1 stop Houston George Bush Intcntl

$607United Airlines

Wed, Jan 27 - Thu, Feb 4

8:00 am - 5:12 pmDSM Des Moines-PTY Panama City Tocumen Intl

8h 12m1 stop Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

11h 55m1 stop Houston George Bush Intcntl

$607United Airlines

Mon, Jan 25 - Wed, Jan 27

8:00 am - 7:38 pmDSM Des Moines-PTY Panama City Tocumen Intl

10h 38m1 stop Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

11h 55m1 stop Houston George Bush Intcntl

$607United Airlines

Mon, Jan 25 - Thu, Jan 28

8:00 am - 5:12 pmDSM Des Moines-PTY Panama City Tocumen Intl

8h 12m1 stop Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

11h 55m1 stop Houston George Bush Intcntl

$607United Airlines

Tue, Jan 26 - Thu, Jan 28

8:00 am - 5:12 pmDSM Des Moines-PTY Panama City Tocumen Intl

8h 12m1 stop Houston George Bush Intcntl

8:55 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

14h 35m1 stop Houston George Bush Intcntl

$607United Airlines

Wed, Jan 27 - Thu, Feb 4

8:00 am - 7:38 pmDSM Des Moines-PTY Panama City Tocumen Intl

10h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 11:16 pmPTY Panama City Tocumen Intl-DSM Des Moines

15h 21m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$611United Airlines

Mon, Jan 25 - Thu, Jan 28

6:30 pm - 5:12 pmDSM Des Moines-PTY Panama City Tocumen Intl

21h 42m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

11h 55m1 stop Houston George Bush Intcntl

$611United Airlines

Sun, Jan 24 - Wed, Jan 27

6:45 pm - 2:45 pmDSM Des Moines-PTY Panama City Tocumen Intl

19h 00m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 10:30 pmPTY Panama City Tocumen Intl-DSM Des Moines

14h 35m1 stop Houston George Bush Intcntl

$611United Airlines

Sun, Nov 8 - Tue, Nov 17

5:39 am - 1:59 pmDSM Des Moines-PTY Panama City Tocumen Intl

7h 20m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 10:35 pmPTY Panama City Tocumen Intl-DSM Des Moines

8h 06m1 stop Atlanta Hartsfield-Jackson

$641Delta

Sun, Nov 8 - Tue, Nov 17

10:55 am - 1:55 pmDSM Des Moines-PTY Panama City Tocumen Intl

26h 00m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

3:20 pm - 8:52 pmPTY Panama City Tocumen Intl-DSM Des Moines

30h 32m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County

$645Delta

Mon, Jan 25 - Sat, Jan 30

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American Airlines flights from Des Moines to Panama

Our best American Airlines deals on Des Moines to Panama flight tickets

American Airlines

Nov 2

DSM5:00 amDes Moines

8h 13m

1 stop

PTY2:13 pmPanama City Tocumen Intl

Apr 1

PTY1:44 pmPanama City Tocumen Intl

10h 12m

1 stop

DSM11:56 pmDes Moines

$691

American Airlines

Nov 2

DSM5:00 amDes Moines

8h 13m

1 stop

PTY2:13 pmPanama City Tocumen Intl

Apr 1

PTY1:44 pmPanama City Tocumen Intl

10h 12m

1 stop

DSM11:56 pmDes Moines

$706

American Airlines

Nov 2

DSM5:00 amDes Moines

8h 13m

1 stop

PTY2:13 pmPanama City Tocumen Intl

Nov 9

PTY3:13 pmPanama City Tocumen Intl

9h 46m

1 stop

DSM11:59 pmDes Moines

$730

United Airlines flights from Des Moines to Panama

Our best United Airlines deals on Des Moines to Panama flight tickets

United Airlines

Jan 25

DSM8:00 amDes Moines

10h 38m

1 stop

PTY7:38 pmPanama City Tocumen Intl

Jan 28

PTY11:35 amPanama City Tocumen Intl

11h 55m

1 stop

DSM10:30 pmDes Moines

$607

United Airlines

Jan 24

DSM6:30 pmDes Moines

19h 15m

2 stops

PTY2:45 pmPanama City Tocumen Intl

Jan 28

PTY11:35 amPanama City Tocumen Intl

11h 55m

1 stop

DSM10:30 pmDes Moines

$611

United Airlines

Nov 8

DSM6:45 pmDes Moines

23h 53m

2 stops

PTY7:38 pmPanama City Tocumen Intl

Nov 16

PTY4:41 pmPanama City Tocumen Intl

22h 39m

1 stop

DSM2:20 pmDes Moines

$622

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Wed 1/27

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Thu 2/4

8:55 am-10:30 pm

1 stop14h 35m

$607

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 1/25

8:00 am-5:12 pm

1 stop8h 12m

Panama City Tocumen Intl

Wed 1/27

11:35 am-10:30 pm

1 stop11h 55m

$607

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 1/25

8:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Thu 1/28

11:35 am-10:30 pm

1 stop11h 55m

$607

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Tue 1/26

8:00 am-5:12 pm

1 stop8h 12m

Panama City Tocumen Intl

Thu 1/28

11:35 am-10:30 pm

1 stop11h 55m

$607

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Wed 1/27

8:00 am-5:12 pm

1 stop8h 12m

Panama City Tocumen Intl

Thu 2/4

8:55 am-10:30 pm

1 stop14h 35m

$607

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 1/25

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Thu 1/28

8:55 am-11:16 pm

2 stops15h 21m

$611

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Sun 1/24

6:30 pm-5:12 pm

2 stops21h 42m

Panama City Tocumen Intl

Wed 1/27

11:35 am-10:30 pm

1 stop11h 55m

$611

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Sun 11/8

6:45 pm-2:45 pm

2 stops19h 00m

Panama City Tocumen Intl

Tue 11/17

8:55 am-10:30 pm

1 stop14h 35m

$611

Quickest round-trip

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Sun 11/8

5:39 am-1:59 pm

1 stop7h 20m

Panama City Tocumen Intl

Tue 11/17

3:29 pm-10:35 pm

1 stop8h 06m

$641

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 1/25

10:55 am-1:55 pm

2 stops26h 00m

Panama City Tocumen Intl

Sat 1/30

3:20 pm-8:52 pm

2 stops30h 32m

$645

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Des Moines, with most prices found around $0. If you don’t want to visit Panama in August, then you should wait until May to fly from Des Moines, when ticket prices are also cheap, with an average price of $461.

Can stopping save me money on Des Moines to Panama flights?

You could potentially save up to 21% on your flight if you consider stops on a Des Moines to Panama flight.

Cheap Des Moines to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Panama

Best Price Found	$607
Fastest flight time	10h 38m
Direct flights	None

The best flight deal from Des Moines to Panama found on momondo in the last 72 hours is $607

The fastest flight from Des Moines to Panama takes 10h 38m

There are no direct flights from Des Moines to Panama. There are no popular flight routes from Des Moines to Panama.

Search flight deals

Frequently asked questions about flying from Des Moines to Panama

When did momondo last update prices for flights from Des Moines Airport to Panama?
Prices for flights from Des Moines Airport to Panama were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Panama?
As of September 2026, there is 1 operator available to choose from for flights from Des Moines Airport to Panama.
How old do you have to be to fly from Des Moines Airport to Panama?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Panama

Compare and see reviews for airlines that fly from Des Moines to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $461	Free Cancellation	Rating 7.4 10,232 reviews		Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Panama for you.

Can I find flights from Des Moines to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Des Moines.

I’m not ready to book a flight from Des Moines to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Des Moines to Panama from $607

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Panama departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Des Moines to Panama

Our best American Airlines deals on Des Moines to Panama flight tickets

United Airlines flights from Des Moines to Panama

Our best United Airlines deals on Des Moines to Panama flight tickets

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How to get the cheapest flight ticket from Des Moines to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Des Moines to Panama flights?

Cheap Des Moines to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Des Moines to Panama

Best airlines flying from Des Moines to Panama

Compare and see reviews for airlines that fly from Des Moines to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Des Moines flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year