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Cheap flights from Des Moines to Madrid from $421

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Madrid departing on 3/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:26 am - 11:45 am
DSM
-
MAD
18h 19m
2 stops
Multiple Airlines Logo
6:25 am - 9:40 pm
MAD
-
DSM
21h 15m
2 stops
$469Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
United Airlines Logo
3:28 pm - 11:45 am
DSM
-
MAD
14h 17m
2 stops
United Airlines Logo
6:25 am - 9:40 pm
MAD
-
DSM
21h 15m
2 stops
$491United Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
11:26 am - 7:00 am
DSM
-
MAD
37h 34m
2 stops
Multiple Airlines Logo
6:35 pm - 6:08 pm
MAD
-
DSM
53h 33m
2 stops
$498Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
2:04 pm - 7:00 am
DSM
-
MAD
34h 56m
2 stops
Multiple Airlines Logo
6:35 pm - 6:08 pm
MAD
-
DSM
53h 33m
2 stops
$499Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Scandinavian Airlines Logo
11:33 am - 8:05 am
DSM
-
MAD
14h 32m
1 stop
Scandinavian Airlines Logo
10:05 am - 10:38 pm
MAD
-
DSM
18h 33m
1 stop
$569Scandinavian Airlines
Tue, Mar 17 - Tue, Mar 24
Delta Logo
11:33 am - 8:05 am
DSM
-
MAD
14h 32m
1 stop
Delta Logo
12:35 pm - 9:46 am
MAD
-
DSM
27h 11m
2 stops
$584Delta
Tue, Mar 17 - Tue, Mar 24
Air Canada Logo
1:10 pm - 6:50 am
DSM
-
MAD
34h 40m
2 stops
Air Canada Logo
12:45 pm - 2:24 pm
MAD
-
DSM
32h 39m
2 stops
$586Air Canada
Sat, Apr 25 - Tue, May 5
Delta Logo
11:33 am - 8:05 am
DSM
-
MAD
14h 32m
1 stop
Delta Logo
1:05 pm - 10:48 am
MAD
-
DSM
27h 43m
2 stops
$595Delta
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
11:17 am - 6:15 am
DSM
-
MAD
12h 58m
1 stop
American Airlines Logo
1:00 pm - 11:40 pm
MAD
-
DSM
16h 40m
1 stop
$610American Airlines
Tue, Mar 17 - Tue, Mar 24
Iberia Logo
7:56 pm - 7:55 am
DSM
-
MAD
28h 59m
1 stop
Iberia Logo
11:35 am - 11:30 pm
MAD
-
DSM
18h 55m
1 stop
$615Iberia
Sat, Apr 25 - Tue, May 5

American Airlines flights from Des Moines to Madrid

Our best American Airlines deals on Des Moines to Madrid flight tickets
American Airlines
Mar 4
DSM7:15 amDes Moines
15h 30m
1 stop
MAD5:45 amMadrid Barajas
Mar 11
MAD11:25 amMadrid Barajas
18h 17m
1 stop
DSM11:42 pmDes Moines
$560
American Airlines
Mar 17
DSM11:17 amDes Moines
12h 58m
1 stop
MAD6:15 amMadrid Barajas
Mar 24
MAD1:00 pmMadrid Barajas
16h 40m
1 stop
DSM11:40 pmDes Moines
$610
American Airlines
Mar 18
DSM11:17 amDes Moines
15h 08m
1 stop
MAD8:25 amMadrid Barajas
Mar 25
MAD12:00 pmMadrid Barajas
16h 34m
1 stop
DSM10:34 pmDes Moines
$702

Delta flights from Des Moines to Madrid

Our best Delta deals on Des Moines to Madrid flight tickets
Delta
Apr 26
DSM2:44 pmDes Moines
14h 31m
1 stop
MAD12:15 pmMadrid Barajas
May 4
MAD2:35 pmMadrid Barajas
27h 30m
2 stops
DSM11:05 amDes Moines
$546
Delta
Mar 17
DSM11:33 amDes Moines
14h 32m
1 stop
MAD8:05 amMadrid Barajas
Mar 24
MAD12:35 pmMadrid Barajas
27h 11m
2 stops
DSM9:46 amDes Moines
$584
Delta
Mar 17
DSM11:33 amDes Moines
14h 32m
1 stop
MAD8:05 amMadrid Barajas
Mar 24
MAD1:05 pmMadrid Barajas
27h 43m
2 stops
DSM10:48 amDes Moines
$595

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 3/19

11:26 am-11:45 am

2 stops18h 19m

Madrid Barajas

Thu 3/26

6:25 am-9:40 pm

2 stops21h 15m

$469

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 3/19

3:28 pm-11:45 am

2 stops14h 17m

Madrid Barajas

Thu 3/26

6:25 am-9:40 pm

2 stops21h 15m

$491

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

11:26 am-7:00 am

2 stops37h 34m

Madrid Barajas

Tue 3/24

6:35 pm-6:08 pm

2 stops53h 33m

$498

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

2:04 pm-7:00 am

2 stops34h 56m

Madrid Barajas

Tue 3/24

6:35 pm-6:08 pm

2 stops53h 33m

$499

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

11:33 am-8:05 am

1 stop14h 32m

Madrid Barajas

Tue 3/24

10:05 am-10:38 pm

1 stop18h 33m

$569

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

11:33 am-8:05 am

1 stop14h 32m

Madrid Barajas

Tue 3/24

12:35 pm-9:46 am

2 stops27h 11m

$584

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sat 4/25

1:10 pm-6:50 am

2 stops34h 40m

Madrid Barajas

Tue 5/5

12:45 pm-2:24 pm

2 stops32h 39m

$586

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

11:33 am-8:05 am

1 stop14h 32m

Madrid Barajas

Tue 3/24

1:05 pm-10:48 am

2 stops27h 43m

$595

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 3/17

11:17 am-6:15 am

1 stop12h 58m

Madrid Barajas

Tue 3/24

1:00 pm-11:40 pm

1 stop16h 40m

$610

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sat 4/25

7:56 pm-7:55 am

1 stop28h 59m

Madrid Barajas

Tue 5/5

11:35 am-11:30 pm

1 stop18h 55m

$615

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Madrid from

How to get the cheapest flight ticket from Des Moines to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Madrid?

What is the cheapest month to fly to Madrid?

The month of January is, on average, the cheapest month to fly to Madrid from Des Moines, with most prices found around $488. If you don’t want to visit Madrid in January, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $529.

Can stopping save me money on Des Moines to Madrid flights?

You could potentially save up to 61% on your flight if you consider stops on a Des Moines to Madrid flight.

When to book flights from Des Moines to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Madrid (DSM to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Madrid

Fastest flight time

14h 48m

Direct flights

None
The fastest flight from Des Moines to Madrid takes 14h 48m
There are no direct flights from Des Moines to Madrid. There are no popular flight routes from Des Moines to Madrid.
Search flight deals

  • How far is Des Moines to Madrid Barajas by plane?

    The distance between Des Moines and Madrid Barajas is about 4451.0 mi. Flights usually cover this in 14h 48m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Madrid Barajas Airport?

    Prices for flights from Des Moines Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Des Moines Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents you'll need for your trip to Madrid Barajas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Madrid Barajas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Madrid?

Best airlines flying from Des Moines to Madrid

Compare and see reviews for airlines that fly from Des Moines to Madrid with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $488Free CancellationRating
7.9
8,142 reviews
Search Delta flights
American AirlinesPriceFrom $513Free CancellationRating
7.2
11,218 reviews
Search American Airlines flights
IberiaPriceFrom $636Free CancellationRating
7.0
3,104 reviews
Search Iberia flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Madrid?

It is quick and easy to find Des Moines to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Des Moines to Madrid with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Madrid flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Madrid?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Madrid from Des Moines.

I’m not ready to book a flight from Des Moines to Madrid right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Madrid from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Fly your favorite airline to Madrid

Airlines are sorted and displayed according to clicks in the past 7 days on momondo
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