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Cheap flights from Des Moines to Madrid from $394

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Madrid departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
1:10 pm - 5:40 pm
DSM
-
MAD
21h 30m
2 stops
Lufthansa Logo
5:55 am - 11:17 pm
MAD
-
DSM
24h 22m
2 stops
$697Lufthansa
Wed, Apr 15 - Tue, Apr 28
Lufthansa Logo
7:16 pm - 11:40 pm
DSM
-
MAD
21h 24m
2 stops
Lufthansa Logo
5:55 am - 11:17 pm
MAD
-
DSM
24h 22m
2 stops
$708Lufthansa
Tue, Apr 14 - Tue, Apr 21
British Airways Logo
8:03 pm - 1:30 pm
DSM
-
MAD
10h 27m
1 stop
British Airways Logo
1:35 pm - 11:49 pm
MAD
-
DSM
17h 14m
1 stop
$724British Airways
Tue, Apr 14 - Tue, Apr 21
American Airlines Logo
2:16 pm - 8:20 am
DSM
-
MAD
11h 04m
1 stop
American Airlines Logo
11:45 am - 11:49 pm
MAD
-
DSM
19h 04m
1 stop
$729American Airlines
Wed, Apr 15 - Tue, Apr 28
Multiple Airlines Logo
8:56 am - 8:20 am
DSM
-
MAD
16h 24m
1 stop
Multiple Airlines Logo
12:30 pm - 11:49 pm
MAD
-
DSM
18h 19m
2 stops
$734Multiple Airlines
Tue, Apr 14 - Tue, Apr 21
Lufthansa Logo
7:16 pm - 5:40 pm
DSM
-
MAD
15h 24m
2 stops
Lufthansa Logo
5:55 am - 11:17 pm
MAD
-
DSM
24h 22m
2 stops
$743Lufthansa
Wed, Apr 15 - Mon, Apr 27
Lufthansa Logo
7:16 pm - 11:40 pm
DSM
-
MAD
21h 24m
2 stops
Lufthansa Logo
5:55 am - 9:32 pm
MAD
-
DSM
22h 37m
2 stops
$754Lufthansa
Wed, Apr 15 - Tue, Apr 28
American Airlines Logo
11:09 am - 8:20 am
DSM
-
MAD
14h 11m
1 stop
American Airlines Logo
11:45 am - 7:33 pm
MAD
-
DSM
14h 48m
1 stop
$779American Airlines
Wed, Apr 15 - Mon, Apr 27
American Airlines Logo
8:56 am - 8:20 am
DSM
-
MAD
16h 24m
1 stop
American Airlines Logo
3:25 pm - 11:49 pm
MAD
-
DSM
15h 24m
2 stops
$784American Airlines
Wed, Apr 15 - Mon, Apr 27
Lufthansa Logo
7:16 pm - 11:40 pm
DSM
-
MAD
21h 24m
2 stops
Lufthansa Logo
5:55 am - 11:17 pm
MAD
-
DSM
24h 22m
2 stops
$787Lufthansa
Wed, Apr 15 - Tue, Apr 28

British Airways flights from Des Moines to Madrid

Our best British Airways deals on Des Moines to Madrid flight tickets
British Airways
Apr 14
DSM8:03 pmDes Moines
10h 27m
1 stop
MAD1:30 pmMadrid Barajas
Apr 21
MAD1:35 pmMadrid Barajas
17h 14m
1 stop
DSM11:49 pmDes Moines
$724
British Airways
May 6
DSM8:03 pmDes Moines
10h 27m
1 stop
MAD1:30 pmMadrid Barajas
May 13
MAD1:35 pmMadrid Barajas
12h 58m
1 stop
DSM7:33 pmDes Moines
$809
British Airways
May 6
DSM2:16 pmDes Moines
16h 14m
1 stop
MAD1:30 pmMadrid Barajas
May 13
MAD11:45 amMadrid Barajas
14h 48m
1 stop
DSM7:33 pmDes Moines
$814

Delta flights from Des Moines to Madrid

Our best Delta deals on Des Moines to Madrid flight tickets
Delta
Apr 27
DSM2:44 pmDes Moines
14h 31m
1 stop
MAD12:15 pmMadrid Barajas
May 27
MAD10:25 amMadrid Barajas
17h 38m
2 stops
DSM9:03 pmDes Moines
$820
Delta
Mar 26
DSM10:51 amDes Moines
18h 39m
2 stops
MAD11:30 amMadrid Barajas
Apr 12
MAD6:00 amMadrid Barajas
23h 38m
2 stops
DSM10:38 pmDes Moines
$1,020
Delta
Mar 26
DSM10:51 amDes Moines
18h 39m
2 stops
MAD11:30 amMadrid Barajas
Apr 12
MAD6:00 amMadrid Barajas
21h 45m
2 stops
DSM8:45 pmDes Moines
$1,070

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

1:10 pm-5:40 pm

2 stops21h 30m

Madrid Barajas

Tue 4/28

5:55 am-11:17 pm

2 stops24h 22m

$697

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 4/14

7:16 pm-11:40 pm

2 stops21h 24m

Madrid Barajas

Tue 4/21

5:55 am-11:17 pm

2 stops24h 22m

$708
Quickest round-trip

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 4/14

8:03 pm-1:30 pm

1 stop10h 27m

Madrid Barajas

Tue 4/21

1:35 pm-11:49 pm

1 stop17h 14m

$724

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

2:16 pm-8:20 am

1 stop11h 04m

Madrid Barajas

Tue 4/28

11:45 am-11:49 pm

1 stop19h 04m

$729

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 4/14

8:56 am-8:20 am

1 stop16h 24m

Madrid Barajas

Tue 4/21

12:30 pm-11:49 pm

2 stops18h 19m

$734

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

7:16 pm-5:40 pm

2 stops15h 24m

Madrid Barajas

Mon 4/27

5:55 am-11:17 pm

2 stops24h 22m

$743

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

7:16 pm-11:40 pm

2 stops21h 24m

Madrid Barajas

Tue 4/28

5:55 am-9:32 pm

2 stops22h 37m

$754

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

11:09 am-8:20 am

1 stop14h 11m

Madrid Barajas

Mon 4/27

11:45 am-7:33 pm

1 stop14h 48m

$779

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

8:56 am-8:20 am

1 stop16h 24m

Madrid Barajas

Mon 4/27

3:25 pm-11:49 pm

2 stops15h 24m

$784

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

7:16 pm-11:40 pm

2 stops21h 24m

Madrid Barajas

Tue 4/28

5:55 am-11:17 pm

2 stops24h 22m

$787

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Madrid from

How to get the cheapest flight ticket from Des Moines to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of January is, on average, the cheapest month to fly to Madrid from Des Moines, with most prices found around $488. If you don’t want to visit Madrid in January, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $573.

Can stopping save me money on Des Moines to Madrid flights?

You could potentially save up to 54% on your flight if you consider stops on a Des Moines to Madrid flight.

When to book flights from Des Moines to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Madrid (DSM to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Madrid

Fastest flight time

16h 10m

Direct flights

None
The fastest flight from Des Moines to Madrid takes 16h 10m
There are no direct flights from Des Moines to Madrid. There are no popular flight routes from Des Moines to Madrid.
Search flight deals

  • How far is Des Moines to Madrid Barajas by plane?

    The distance between Des Moines and Madrid Barajas is about 4451.0 mi. Flights usually cover this in 16h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Madrid Barajas Airport?

    Prices for flights from Des Moines Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Des Moines Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents you'll need for your trip to Madrid Barajas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Madrid Barajas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Madrid?

Best airlines flying from Des Moines to Madrid

Compare and see reviews for airlines that fly from Des Moines to Madrid with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $488Free CancellationRating
7.9
8,319 reviews
Search Delta flights
American AirlinesPriceFrom $493Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
IberiaPriceFrom $628Free CancellationRating
7.0
3,147 reviews
Search Iberia flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Madrid?

It is quick and easy to find Des Moines to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Des Moines to Madrid with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Madrid flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Madrid?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Madrid from Des Moines.

I’m not ready to book a flight from Des Moines to Madrid right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Madrid from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo
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