Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Madrid from $443

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Madrid departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Virgin Atlantic Logo
10:57 am - 8:00 amDSM-MAD
14h 03m2 stops
Virgin Atlantic Logo
9:00 am - 8:53 pmMAD-DSM
17h 53m2 stops
$443Virgin Atlantic
Find Deal
Wed, Feb 25 - Tue, Mar 10
Delta Logo
11:23 am - 3:20 pmDSM-MAD
20h 57m2 stops
Delta Logo
10:00 am - 10:34 pmMAD-DSM
19h 34m2 stops
$461Delta
Find Deal
Tue, Dec 9 - Tue, Dec 16
Air Canada Logo
5:15 pm - 8:00 amDSM-MAD
31h 45m2 stops
Air Canada Logo
1:35 pm - 10:29 amMAD-DSM
27h 54m2 stops
$465Air Canada
Find Deal
Wed, Dec 3 - Wed, Dec 10
KLM Logo
6:33 pm - 9:15 amDSM-MAD
31h 42m1 stop
KLM Logo
11:15 am - 10:34 pmMAD-DSM
18h 19m1 stop
$468KLM
Find Deal
Wed, Dec 3 - Wed, Dec 10
Multiple Airlines Logo
3:17 pm - 8:00 amDSM-MAD
33h 43m2 stops
Multiple Airlines Logo
6:00 am - 5:24 pmMAD-DSM
18h 24m2 stops
$478Multiple Airlines
Find Deal
Tue, Dec 9 - Tue, Dec 16
United Airlines Logo
9:00 am - 8:00 amDSM-MAD
16h 00m2 stops
United Airlines Logo
6:00 am - 5:24 pmMAD-DSM
18h 24m2 stops
$487United Airlines
Find Deal
Tue, Dec 9 - Tue, Dec 16
Multiple Airlines Logo
6:33 pm - 9:15 amDSM-MAD
31h 42m1 stop
Multiple Airlines Logo
6:00 am - 4:16 pmMAD-DSM
17h 16m2 stops
$492Multiple Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Multiple Airlines Logo
6:33 am - 8:50 amDSM-MAD
19h 17m1 stop
Multiple Airlines Logo
1:00 pm - 9:53 pmMAD-DSM
14h 53m1 stop
$497Multiple Airlines
Find Deal
Wed, Feb 25 - Tue, Mar 10
American Airlines Logo
6:00 am - 7:55 amDSM-MAD
18h 55m1 stop
American Airlines Logo
1:15 pm - 10:29 pmMAD-DSM
16h 14m2 stops
$562American Airlines
Find Deal
Tue, Dec 9 - Tue, Dec 16
American Airlines Logo
6:33 am - 8:50 amDSM-MAD
19h 17m1 stop
American Airlines Logo
12:55 am - 4:17 pmMAD-DSM
21h 22m1 stop
$570American Airlines
Find Deal
Wed, Feb 25 - Mon, Mar 9

Delta flights from Des Moines to Madrid

Our best Delta deals on Des Moines to Madrid flight tickets
Delta
Dec 9
DSM11:23 amDes Moines
20h 57m
2 stops
MAD3:20 pmMadrid Barajas
Dec 16
MAD10:00 amMadrid Barajas
19h 34m
2 stops
DSM10:34 pmDes Moines
$461
Find similar
Delta
Mar 17
DSM11:04 amDes Moines
15h 01m
1 stop
MAD8:05 amMadrid Barajas
Mar 31
MAD10:05 amMadrid Barajas
13h 25m
1 stop
DSM4:30 pmDes Moines
$722
Find similar
Delta
Mar 16
DSM11:04 amDes Moines
15h 01m
1 stop
MAD8:05 amMadrid Barajas
Mar 31
MAD10:05 amMadrid Barajas
13h 25m
1 stop
DSM4:30 pmDes Moines
$857
Find similar

United Airlines flights from Des Moines to Madrid

Our best United Airlines deals on Des Moines to Madrid flight tickets
United Airlines
Dec 9
DSM9:00 amDes Moines
16h 00m
2 stops
MAD8:00 amMadrid Barajas
Dec 16
MAD6:00 amMadrid Barajas
18h 24m
2 stops
DSM5:24 pmDes Moines
$487
Find similar
United Airlines
Feb 25
DSM11:30 amDes Moines
14h 45m
2 stops
MAD9:15 amMadrid Barajas
Mar 10
MAD6:25 amMadrid Barajas
20h 16m
3 stops
DSM8:41 pmDes Moines
$537
Find similar
United Airlines
Mar 27
DSM3:15 pmDes Moines
14h 30m
2 stops
MAD11:45 amMadrid Barajas
Mar 31
MAD6:00 amMadrid Barajas
18h 33m
2 stops
DSM5:33 pmDes Moines
$734
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 2/25

10:57 am-8:00 am

2 stops14h 03m

Madrid Barajas

Tue 3/10

9:00 am-8:53 pm

2 stops17h 53m

$443

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 12/9

11:23 am-3:20 pm

2 stops20h 57m

Madrid Barajas

Tue 12/16

10:00 am-10:34 pm

2 stops19h 34m

$461

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 12/3

5:15 pm-8:00 am

2 stops31h 45m

Madrid Barajas

Wed 12/10

1:35 pm-10:29 am

2 stops27h 54m

$465

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 12/3

6:33 pm-9:15 am

1 stop31h 42m

Madrid Barajas

Wed 12/10

11:15 am-10:34 pm

1 stop18h 19m

$468

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 12/9

3:17 pm-8:00 am

2 stops33h 43m

Madrid Barajas

Tue 12/16

6:00 am-5:24 pm

2 stops18h 24m

$478

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 12/9

9:00 am-8:00 am

2 stops16h 00m

Madrid Barajas

Tue 12/16

6:00 am-5:24 pm

2 stops18h 24m

$487

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 12/3

6:33 pm-9:15 am

1 stop31h 42m

Madrid Barajas

Wed 12/10

6:00 am-4:16 pm

2 stops17h 16m

$492

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 2/25

6:33 am-8:50 am

1 stop19h 17m

Madrid Barajas

Tue 3/10

1:00 pm-9:53 pm

1 stop14h 53m

$497

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 12/9

6:00 am-7:55 am

1 stop18h 55m

Madrid Barajas

Tue 12/16

1:15 pm-10:29 pm

2 stops16h 14m

$562

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 2/25

6:33 am-8:50 am

1 stop19h 17m

Madrid Barajas

Mon 3/9

12:55 am-4:17 pm

1 stop21h 22m

$570

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Madrid from

How to get the cheapest flight ticket from Des Moines to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of February is, on average, the cheapest month to fly to Madrid from Des Moines, with most prices found around $634. If you don’t want to visit Madrid in February, then you should wait until January to fly from Des Moines, when ticket prices are also cheap, with an average price of $635.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Sunday when prices can be found for as low as $792. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Thursday is $1,374.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $958 when looking at flights departing in the afternoon. Flights to Madrid are more costly in the morning, with an average ticket price of $997. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Des Moines to Madrid flights?

You could potentially save up to 16% on your flight if you consider stops on a Des Moines to Madrid flight.

When to book flights from Des Moines to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Madrid (DSM to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Madrid

Direct flights

None
There are no direct flights from Des Moines to Madrid. There are no popular flight routes from Des Moines to Madrid.
Search flight deals

  • How far is Des Moines to Madrid Barajas by plane?

    The distance between Des Moines and Madrid Barajas is about 4451.0 mi. Flights usually cover this in 11h 59m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Madrid Barajas Airport?

    Prices for flights from Des Moines Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Des Moines Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents you'll need for your trip to Madrid Barajas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Madrid Barajas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Madrid?

Best airlines flying from Des Moines to Madrid

Compare and see reviews for airlines that fly from Des Moines to Madrid with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $586Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights
DeltaPriceFrom $644Free CancellationRating
7.9
8,002 reviews
Search Delta flights
IberiaPriceFrom $686Free CancellationRating
7.0
3,006 reviews
Search Iberia flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
San Lorenzo de El Escorial
Cuenca
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Madrid?

It is quick and easy to find Des Moines to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Des Moines to Madrid with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Madrid flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Madrid?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Madrid from Des Moines.

I’m not ready to book a flight from Des Moines to Madrid right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Madrid from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Madrid trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 12/4
Thu 12/11
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Spain

Fly your favorite airline to Madrid

Airlines are sorted and displayed according to clicks in the past 7 days on momondo
Delta
American Airlines
United Airlines
Turkish Airlines
Lufthansa
Frontier
British Airways
Qatar Airways
Spirit Airlines
Ryanair
Alaska Airlines
Emirates