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Cheap flights from Des Moines to Madrid from $378

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Madrid departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:15 am - 9:00 am
DSM
-
MAD
19h 45m
2 stops
United Airlines Logo
12:35 pm - 2:11 pm
MAD
-
DSM
31h 36m
2 stops
$700United Airlines
Wed, Oct 14 - Wed, Oct 28
United Airlines Logo
8:15 pm - 8:00 am
DSM
-
MAD
28h 45m
2 stops
United Airlines Logo
1:35 pm - 9:17 pm
MAD
-
DSM
38h 42m
2 stops
$703United Airlines
Sun, Nov 1 - Tue, Nov 10
United Airlines Logo
8:00 am - 8:05 am
DSM
-
MAD
17h 05m
2 stops
United Airlines Logo
1:30 pm - 2:11 pm
MAD
-
DSM
31h 41m
2 stops
$705United Airlines
Sun, Sep 27 - Tue, Oct 6
United Airlines Logo
6:15 am - 9:00 am
DSM
-
MAD
19h 45m
2 stops
United Airlines Logo
6:00 am - 12:40 am
MAD
-
DSM
24h 40m
2 stops
$720United Airlines
Wed, Oct 14 - Wed, Oct 28
Delta Logo
11:04 am - 12:15 pm
DSM
-
MAD
18h 11m
1 stop
Delta Logo
1:05 pm - 10:18 am
MAD
-
DSM
27h 13m
2 stops
$722Delta
Wed, Oct 14 - Wed, Oct 28
Multiple Airlines Logo
5:35 pm - 3:35 pm
DSM
-
MAD
15h 00m
2 stops
Multiple Airlines Logo
9:50 am - 10:29 pm
MAD
-
DSM
19h 39m
1 stop
$724Multiple Airlines
Sun, Sep 27 - Tue, Oct 6
Delta Logo
11:04 am - 12:15 pm
DSM
-
MAD
18h 11m
1 stop
Delta Logo
9:50 am - 8:52 pm
MAD
-
DSM
18h 02m
2 stops
$725Delta
Mon, Sep 28 - Fri, Oct 9
Delta Logo
10:15 am - 6:20 am
DSM
-
MAD
13h 05m
2 stops
Delta Logo
9:50 am - 1:27 pm
MAD
-
DSM
34h 37m
1 stop
$730Delta
Wed, Sep 30 - Fri, Oct 9
British Airways Logo
1:24 pm - 1:25 pm
DSM
-
MAD
17h 01m
1 stop
British Airways Logo
12:00 pm - 11:44 pm
MAD
-
DSM
18h 44m
2 stops
$732British Airways
Sun, Nov 1 - Tue, Nov 10
United Airlines Logo
6:15 am - 9:00 am
DSM
-
MAD
19h 45m
2 stops
United Airlines Logo
5:55 am - 11:01 pm
MAD
-
DSM
24h 06m
2 stops
$770United Airlines
Mon, Sep 28 - Sat, Oct 10

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British Airways flights from Des Moines to Madrid

Our best British Airways deals on Des Moines to Madrid flight tickets
British Airways
Nov 1
DSM1:24 pmDes Moines
17h 01m
1 stop
MAD1:25 pmMadrid Barajas
Nov 10
MAD12:00 pmMadrid Barajas
18h 44m
2 stops
DSM11:44 pmDes Moines
$732
British Airways
Oct 16
DSM6:07 pmDes Moines
31h 13m
1 stop
MAD8:20 amMadrid Barajas
Oct 19
MAD9:00 pmMadrid Barajas
30h 11m
2 stops
DSM8:11 pmDes Moines
$816
British Airways
May 20
DSM2:24 pmDes Moines
17h 36m
2 stops
MAD3:00 pmMadrid Barajas
May 26
MAD11:45 amMadrid Barajas
13h 51m
1 stop
DSM6:36 pmDes Moines
$1,300

KLM flights from Des Moines to Madrid

Our best KLM deals on Des Moines to Madrid flight tickets
KLM
Aug 4
DSM3:00 pmDes Moines
14h 15m
1 stop
MAD12:15 pmMadrid Barajas
Aug 21
MAD7:05 amMadrid Barajas
17h 06m
2 stops
DSM5:11 pmDes Moines
$803
KLM
Aug 3
DSM2:48 pmDes Moines
14h 27m
1 stop
MAD12:15 pmMadrid Barajas
Aug 21
MAD9:50 amMadrid Barajas
14h 52m
1 stop
DSM5:42 pmDes Moines
$809
KLM
Aug 3
DSM2:48 pmDes Moines
14h 27m
1 stop
MAD12:15 pmMadrid Barajas
Aug 21
MAD7:05 amMadrid Barajas
16h 44m
2 stops
DSM4:49 pmDes Moines
$811

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/14

6:15 am-9:00 am

2 stops19h 45m

Madrid Barajas

Wed 10/28

12:35 pm-2:11 pm

2 stops31h 36m

$700

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 11/1

8:15 pm-8:00 am

2 stops28h 45m

Madrid Barajas

Tue 11/10

1:35 pm-9:17 pm

2 stops38h 42m

$703

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 9/27

8:00 am-8:05 am

2 stops17h 05m

Madrid Barajas

Tue 10/6

1:30 pm-2:11 pm

2 stops31h 41m

$705

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/14

6:15 am-9:00 am

2 stops19h 45m

Madrid Barajas

Wed 10/28

6:00 am-12:40 am

2 stops24h 40m

$720

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/14

11:04 am-12:15 pm

1 stop18h 11m

Madrid Barajas

Wed 10/28

1:05 pm-10:18 am

2 stops27h 13m

$722
Quickest round-trip

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 9/27

5:35 pm-3:35 pm

2 stops15h 00m

Madrid Barajas

Tue 10/6

9:50 am-10:29 pm

1 stop19h 39m

$724

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 9/28

11:04 am-12:15 pm

1 stop18h 11m

Madrid Barajas

Fri 10/9

9:50 am-8:52 pm

2 stops18h 02m

$725

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 9/30

10:15 am-6:20 am

2 stops13h 05m

Madrid Barajas

Fri 10/9

9:50 am-1:27 pm

1 stop34h 37m

$730

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 11/1

1:24 pm-1:25 pm

1 stop17h 01m

Madrid Barajas

Tue 11/10

12:00 pm-11:44 pm

2 stops18h 44m

$732

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 9/28

6:15 am-9:00 am

2 stops19h 45m

Madrid Barajas

Sat 10/10

5:55 am-11:01 pm

2 stops24h 06m

$770

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Madrid?

What is the cheapest month to fly to Madrid?

The month of January is, on average, the cheapest month to fly to Madrid from Des Moines, with most prices found around $488. If you don’t want to visit Madrid in January, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $602.

Can stopping save me money on Des Moines to Madrid flights?

You could potentially save up to 2% on your flight if you consider stops on a Des Moines to Madrid flight.

When to book flights from Des Moines to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Madrid (DSM to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Madrid

Fastest flight time

15h 12m

Direct flights

None
The fastest flight from Des Moines to Madrid takes 15h 12m
There are no direct flights from Des Moines to Madrid. There are no popular flight routes from Des Moines to Madrid.
Search flight deals

Frequently asked questions about flying from Des Moines to Madrid

  • How far is Des Moines to Madrid Barajas by plane?

    The distance between Des Moines and Madrid Barajas is about 4451.0 mi. Flights usually cover this in 15h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Madrid Barajas Airport?

    Prices for flights from Des Moines Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Des Moines Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents you'll need for your trip to Madrid Barajas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Madrid Barajas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Madrid?

Best airlines flying from Des Moines to Madrid

Compare and see reviews for airlines that fly from Des Moines to Madrid with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $488Free CancellationRating
7.9
8,458 reviews
Search Delta flights
American AirlinesPriceFrom $493Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights
IberiaPriceFrom $628Free CancellationRating
7.0
3,212 reviews
Search Iberia flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Madrid?

It is quick and easy to find Des Moines to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Des Moines to Madrid with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Madrid flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Madrid?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Madrid from Des Moines.

I’m not ready to book a flight from Des Moines to Madrid right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Madrid from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Fly your favorite airline to Madrid

Airlines are sorted and displayed according to clicks in the past 7 days on momondo
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Iberia
Delta