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Cheap flights from Des Moines to Madrid from $398

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Madrid departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Virgin Atlantic Logo
5:16 pm - 9:15 am
DSM
-
MAD
32h 59m1 stop
Virgin Atlantic Logo
11:15 am - 8:54 pm
MAD
-
DSM
16h 39m2 stops
$398Virgin Atlantic
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
5:16 pm - 9:15 am
DSM
-
MAD
32h 59m1 stop
Multiple Airlines Logo
11:15 am - 4:28 pm
MAD
-
DSM
36h 13m1 stop
$437Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Lufthansa Logo
6:48 pm - 11:35 pm
DSM
-
MAD
21h 47m2 stops
Lufthansa Logo
6:00 am - 9:50 pm
MAD
-
DSM
22h 50m2 stops
$445Lufthansa
Sat, Jan 31 - Sat, Feb 7
Lufthansa Logo
6:48 pm - 5:50 pm
DSM
-
MAD
16h 02m2 stops
Lufthansa Logo
6:00 am - 9:50 pm
MAD
-
DSM
22h 50m2 stops
$456Lufthansa
Thu, Jan 29 - Thu, Feb 5
Virgin Atlantic Logo
5:16 pm - 9:15 am
DSM
-
MAD
32h 59m1 stop
Virgin Atlantic Logo
11:15 am - 9:24 pm
MAD
-
DSM
41h 09m2 stops
$462Virgin Atlantic
Thu, Jan 29 - Thu, Feb 5
Virgin Atlantic Logo
10:59 am - 8:00 am
DSM
-
MAD
38h 01m2 stops
Virgin Atlantic Logo
11:15 am - 8:54 pm
MAD
-
DSM
16h 39m2 stops
$465Virgin Atlantic
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
11:42 am - 8:50 am
DSM
-
MAD
14h 08m1 stop
Multiple Airlines Logo
12:30 pm - 10:11 pm
MAD
-
DSM
16h 41m2 stops
$470Multiple Airlines
Fri, Jan 30 - Fri, Feb 6
Virgin Atlantic Logo
5:16 pm - 9:15 am
DSM
-
MAD
32h 59m1 stop
Virgin Atlantic Logo
11:15 am - 9:24 pm
MAD
-
DSM
41h 09m2 stops
$471Virgin Atlantic
Thu, Jan 29 - Thu, Feb 5
United Airlines Logo
8:10 am - 9:15 am
DSM
-
MAD
18h 05m2 stops
United Airlines Logo
1:35 pm - 10:55 am
MAD
-
DSM
28h 20m2 stops
$473United Airlines
Fri, Jan 30 - Fri, Feb 6
KLM Logo
5:16 pm - 9:15 am
DSM
-
MAD
32h 59m1 stop
KLM Logo
11:15 am - 4:28 pm
MAD
-
DSM
36h 13m1 stop
$474KLM
Thu, Jan 29 - Thu, Feb 5

Lufthansa flights from Des Moines to Madrid

Our best Lufthansa deals on Des Moines to Madrid flight tickets
Lufthansa
Jan 31
DSM6:48 pmDes Moines
21h 47m
2 stops
MAD11:35 pmMadrid Barajas
Feb 7
MAD6:00 amMadrid Barajas
22h 50m
2 stops
DSM9:50 pmDes Moines
$445
Find similar
Lufthansa
Jan 24
DSM6:48 pmDes Moines
21h 47m
2 stops
MAD11:35 pmMadrid Barajas
Jan 31
MAD6:00 amMadrid Barajas
22h 50m
2 stops
DSM9:50 pmDes Moines
$477
Find similar
Lufthansa
Jan 24
DSM6:48 pmDes Moines
21h 47m
2 stops
MAD11:35 pmMadrid Barajas
Jan 31
MAD6:00 amMadrid Barajas
22h 50m
2 stops
DSM9:50 pmDes Moines
$486
Find similar

United Airlines flights from Des Moines to Madrid

Our best United Airlines deals on Des Moines to Madrid flight tickets
United Airlines
Jan 30
DSM8:10 amDes Moines
18h 05m
2 stops
MAD9:15 amMadrid Barajas
Feb 6
MAD1:35 pmMadrid Barajas
28h 20m
2 stops
DSM10:55 amDes Moines
$473
Find similar
United Airlines
Jan 16
DSM11:30 amDes Moines
21h 40m
2 stops
MAD4:10 pmMadrid Barajas
Jan 20
MAD1:35 pmMadrid Barajas
31h 58m
2 stops
DSM2:33 pmDes Moines
$489
Find similar
United Airlines
Mar 15
DSM8:00 amDes Moines
31h 10m
2 stops
MAD9:10 pmMadrid Barajas
Mar 24
MAD9:05 amMadrid Barajas
35h 17m
2 stops
DSM2:22 pmDes Moines
$509
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

5:16 pm-9:15 am

1 stop32h 59m

Madrid Barajas

Thu 2/5

11:15 am-8:54 pm

2 stops16h 39m

$398

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

5:16 pm-9:15 am

1 stop32h 59m

Madrid Barajas

Thu 2/5

11:15 am-4:28 pm

1 stop36h 13m

$437

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sat 1/31

6:48 pm-11:35 pm

2 stops21h 47m

Madrid Barajas

Sat 2/7

6:00 am-9:50 pm

2 stops22h 50m

$445

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

6:48 pm-5:50 pm

2 stops16h 02m

Madrid Barajas

Thu 2/5

6:00 am-9:50 pm

2 stops22h 50m

$456

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

5:16 pm-9:15 am

1 stop32h 59m

Madrid Barajas

Thu 2/5

11:15 am-9:24 pm

2 stops41h 09m

$462

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

10:59 am-8:00 am

2 stops38h 01m

Madrid Barajas

Thu 2/5

11:15 am-8:54 pm

2 stops16h 39m

$465

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Fri 1/30

11:42 am-8:50 am

1 stop14h 08m

Madrid Barajas

Fri 2/6

12:30 pm-10:11 pm

2 stops16h 41m

$470

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

5:16 pm-9:15 am

1 stop32h 59m

Madrid Barajas

Thu 2/5

11:15 am-9:24 pm

2 stops41h 09m

$471

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Fri 1/30

8:10 am-9:15 am

2 stops18h 05m

Madrid Barajas

Fri 2/6

1:35 pm-10:55 am

2 stops28h 20m

$473

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/29

5:16 pm-9:15 am

1 stop32h 59m

Madrid Barajas

Thu 2/5

11:15 am-4:28 pm

1 stop36h 13m

$474

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Madrid from

How to get the cheapest flight ticket from Des Moines to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Madrid?

What is the cheapest month to fly to Madrid?

The month of November is, on average, the cheapest month to fly to Madrid from Des Moines, with most prices found around $623. If you don’t want to visit Madrid in November, then you should wait until February to fly from Des Moines, when ticket prices are also cheap, with an average price of $624.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Sunday when prices can be found for as low as $792. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Thursday is $1,374.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $958 when looking at flights departing in the afternoon. Flights to Madrid are more costly in the morning, with an average ticket price of $997. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Des Moines to Madrid flights?

You could potentially save up to 16% on your flight if you consider stops on a Des Moines to Madrid flight.

When to book flights from Des Moines to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Madrid (DSM to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Madrid

Fastest flight time

15h 05m

Direct flights

None
The fastest flight from Des Moines to Madrid takes 15h 05m
There are no direct flights from Des Moines to Madrid. There are no popular flight routes from Des Moines to Madrid.
Search flight deals

  • How far is Des Moines to Madrid Barajas by plane?

    The distance between Des Moines and Madrid Barajas is about 4451.0 mi. Flights usually cover this in 15h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Madrid Barajas Airport?

    Prices for flights from Des Moines Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Des Moines Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents you'll need for your trip to Madrid Barajas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Madrid Barajas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Madrid?

Best airlines flying from Des Moines to Madrid

Compare and see reviews for airlines that fly from Des Moines to Madrid with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $586Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
IberiaPriceFrom $636Free CancellationRating
7.0
3,052 reviews
Search Iberia flights
DeltaPriceFrom $659Free CancellationRating
7.9
8,005 reviews
Search Delta flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Madrid?

It is quick and easy to find Des Moines to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Des Moines to Madrid with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Madrid flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Madrid?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Madrid from Des Moines.

I’m not ready to book a flight from Des Moines to Madrid right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Madrid from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo
American Airlines
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