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Cheap flights from Des Moines to Manchester from $387

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Manchester departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Manchester

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:16 pm - 10:30 amDSM-MAN
11h 14m1 stop
Delta Logo
1:00 pm - 10:29 pmMAN-DSM
15h 29m1 stop
$594Delta
Find Deal
Wed, Jan 14 - Sun, Jan 18
Delta Logo
6:24 am - 10:30 amDSM-MAN
22h 06m2 stops
Delta Logo
1:00 pm - 10:29 pmMAN-DSM
15h 29m1 stop
$598Delta
Find Deal
Wed, Jan 14 - Sun, Jan 18
Delta Logo
5:16 pm - 10:30 amDSM-MAN
11h 14m1 stop
Delta Logo
1:30 pm - 10:41 amMAN-DSM
27h 11m1 stop
$599Delta
Find Deal
Fri, Jan 16 - Tue, Jan 20
Virgin Atlantic Logo
5:16 pm - 10:30 amDSM-MAN
11h 14m1 stop
Virgin Atlantic Logo
5:50 am - 9:24 pmMAN-DSM
21h 34m2 stops
$603Virgin Atlantic
Find Deal
Wed, Feb 4 - Sun, Feb 8
Lufthansa Logo
6:48 pm - 5:00 pmDSM-MAN
16h 12m2 stops
Lufthansa Logo
6:25 am - 9:50 pmMAN-DSM
21h 25m2 stops
$605Lufthansa
Find Deal
Fri, Jan 9 - Fri, Jan 16
Virgin Atlantic Logo
12:25 pm - 10:30 amDSM-MAN
16h 05m2 stops
Virgin Atlantic Logo
5:50 am - 9:24 pmMAN-DSM
21h 34m2 stops
$608Virgin Atlantic
Find Deal
Wed, Feb 4 - Sun, Feb 8
Lufthansa Logo
6:48 pm - 5:00 pmDSM-MAN
16h 12m2 stops
Lufthansa Logo
11:15 am - 9:50 pmMAN-DSM
16h 35m2 stops
$610Lufthansa
Find Deal
Fri, Jan 9 - Fri, Jan 16
Delta Logo
11:26 am - 10:30 amDSM-MAN
17h 04m1 stop
Delta Logo
9:00 am - 10:29 pmMAN-DSM
19h 29m1 stop
$619Delta
Find Deal
Thu, Jan 29 - Mon, Feb 2
Delta Logo
10:59 am - 10:30 amDSM-MAN
17h 31m2 stops
Delta Logo
1:00 pm - 9:41 amMAN-DSM
26h 41m2 stops
$623Delta
Find Deal
Fri, Feb 6 - Tue, Feb 10
Delta Logo
5:16 pm - 10:30 amDSM-MAN
11h 14m1 stop
Delta Logo
6:00 am - 8:54 pmMAN-DSM
20h 54m2 stops
$624Delta
Find Deal
Fri, Jan 16 - Tue, Jan 20

Delta flights from Des Moines to Manchester

Our best Delta deals on Des Moines to Manchester flight tickets
Delta
Jan 14
DSM5:16 pmDes Moines
11h 14m
1 stop
MAN10:30 amManchester
Jan 18
MAN1:00 pmManchester
15h 29m
1 stop
DSM10:29 pmDes Moines
$594
Find similar
Delta
Jan 14
DSM6:24 amDes Moines
22h 06m
2 stops
MAN10:30 amManchester
Jan 18
MAN1:00 pmManchester
15h 29m
1 stop
DSM10:29 pmDes Moines
$598
Find similar
Delta
Jan 16
DSM5:16 pmDes Moines
11h 14m
1 stop
MAN10:30 amManchester
Jan 20
MAN1:30 pmManchester
27h 11m
1 stop
DSM10:41 amDes Moines
$599
Find similar

Virgin Atlantic flights from Des Moines to Manchester

Our best Virgin Atlantic deals on Des Moines to Manchester flight tickets
Virgin Atlantic
Feb 4
DSM5:16 pmDes Moines
11h 14m
1 stop
MAN10:30 amManchester
Feb 8
MAN5:50 amManchester
21h 34m
2 stops
DSM9:24 pmDes Moines
$603
Find similar
Virgin Atlantic
Feb 4
DSM12:25 pmDes Moines
16h 05m
2 stops
MAN10:30 amManchester
Feb 8
MAN5:50 amManchester
21h 34m
2 stops
DSM9:24 pmDes Moines
$608
Find similar
Virgin Atlantic
Jan 7
DSM12:04 pmDes Moines
16h 26m
2 stops
MAN10:30 amManchester
Jan 14
MAN1:30 pmManchester
32h 58m
1 stop
DSM4:28 pmDes Moines
$653
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 1/14

5:16 pm-10:30 am

1 stop11h 14m

Manchester

Sun 1/18

1:00 pm-10:29 pm

1 stop15h 29m

$594

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 1/14

6:24 am-10:30 am

2 stops22h 06m

Manchester

Sun 1/18

1:00 pm-10:29 pm

1 stop15h 29m

$598

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 1/16

5:16 pm-10:30 am

1 stop11h 14m

Manchester

Tue 1/20

1:30 pm-10:41 am

1 stop27h 11m

$599

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 2/4

5:16 pm-10:30 am

1 stop11h 14m

Manchester

Sun 2/8

5:50 am-9:24 pm

2 stops21h 34m

$603

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 1/9

6:48 pm-5:00 pm

2 stops16h 12m

Manchester

Fri 1/16

6:25 am-9:50 pm

2 stops21h 25m

$605

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 2/4

12:25 pm-10:30 am

2 stops16h 05m

Manchester

Sun 2/8

5:50 am-9:24 pm

2 stops21h 34m

$608

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 1/9

6:48 pm-5:00 pm

2 stops16h 12m

Manchester

Fri 1/16

11:15 am-9:50 pm

2 stops16h 35m

$610

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 1/29

11:26 am-10:30 am

1 stop17h 04m

Manchester

Mon 2/2

9:00 am-10:29 pm

1 stop19h 29m

$619

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 2/6

10:59 am-10:30 am

2 stops17h 31m

Manchester

Tue 2/10

1:00 pm-9:41 am

2 stops26h 41m

$623

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 1/16

5:16 pm-10:30 am

1 stop11h 14m

Manchester

Tue 1/20

6:00 am-8:54 pm

2 stops20h 54m

$624

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from Des Moines to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Manchester?

What is the cheapest month to fly to Manchester?

The cheapest month to fly to Manchester from Des Moines is in September. Flight prices, which tend to average around $652, are often lower during this time because this is during the off-season. If you don’t want to visit Manchester in September, then you should wait until November to fly from Des Moines, when ticket prices are also cheap, with an average price of $878.

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from Des Moines to Manchester is on a Wednesday. Travelers who choose to depart for Manchester on a Wednesday will often find tickets for as low as $646. On the other hand, Thursday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,448.

What is the cheapest time of day to depart on your flight to Manchester?

Flying to Manchester from Des Moines at noon is the least expensive time of day to depart. momondo users have found prices as low as $756 when looking at flights departing at noon. Flights to Manchester are more costly in the afternoon, with an average ticket price of $1,191. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Des Moines to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Manchester (DSM to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Manchester

Fastest flight time

11h 14m

Direct flights

None
The fastest flight from Des Moines to Manchester takes 11h 14m
There are no direct flights from Des Moines to Manchester. There are no popular flight routes from Des Moines to Manchester.
Search flight deals

  • How far is Des Moines to Manchester by plane?

    The straight-line distance from Des Moines to Manchester is 4038.6 mi. In terms of flight time, this usually takes a little over 11h 14m.

  • When did momondo last update prices for flights from Des Moines Airport to Manchester Airport?

    Prices for flights from Des Moines Airport to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Manchester Airport?

  • How old do you have to be to fly from Des Moines Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents you'll need for your trip to Manchester Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Manchester Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Manchester?

Best airlines flying from Des Moines to Manchester

Compare and see reviews for airlines that fly from Des Moines to Manchester with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom $715Free CancellationRating
6.7
7,539 reviews
Search British Airways flights

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Leicester
Conwy
Chester
Windermere
Ambleside
Telford
Bradford
Sheffield
Derby
Stoke-on-Trent
Lincoln
Southport
Rochdale
Harrogate
Sale
Bolton
Stafford
Warrington

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Manchester?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Manchester for you.

Can I find flights from Des Moines to Manchester with flexible booking policies on momondo?

Yes. All flights to Manchester from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Manchester?

Once you have performed a search for Des Moines to Manchester flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Manchester right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Manchester now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Manchester and let you know when they change.

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