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Cheap flights from Des Moines to Guayaquil from $662

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guayaquil departing on 11/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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United Airlines Logo
6:05 am - 11:41 pmDSM-GYE
16h 36m2 stops
United Airlines Logo
2:35 pm - 10:29 pmGYE-DSM
32h 54m2 stops
$662United Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
United Airlines Logo
6:05 am - 11:41 pmDSM-GYE
16h 36m2 stops
United Airlines Logo
8:30 am - 10:29 pmGYE-DSM
14h 59m2 stops
$721United Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
Multiple Airlines Logo
10:55 am - 5:38 pmDSM-GYE
29h 43m3 stops
Multiple Airlines Logo
6:55 pm - 10:21 pmGYE-DSM
28h 26m2 stops
$788Multiple Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
American Airlines Logo
5:26 pm - 11:06 pmDSM-GYE
28h 40m2 stops
American Airlines Logo
6:10 am - 11:29 pmGYE-DSM
18h 19m1 stop
$790American Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
American Airlines Logo
5:42 am - 11:06 pmDSM-GYE
16h 24m2 stops
American Airlines Logo
6:10 am - 11:29 pmGYE-DSM
18h 19m1 stop
$847American Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
Multiple Airlines Logo
10:55 am - 11:41 pmDSM-GYE
11h 46m2 stops
Multiple Airlines Logo
4:40 am - 10:21 pmGYE-DSM
42h 41m3 stops
$906Multiple Airlines
Find Deal
Sat, Nov 29 - Fri, Dec 5
Multiple Airlines Logo
10:55 am - 5:38 pmDSM-GYE
29h 43m3 stops
Multiple Airlines Logo
9:05 am - 10:21 pmGYE-DSM
38h 16m3 stops
$939Multiple Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
American Airlines Logo
6:00 am - 11:06 pmDSM-GYE
16h 06m1 stop
American Airlines Logo
6:10 am - 11:29 pmGYE-DSM
18h 19m1 stop
$999American Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
American Airlines Logo
6:00 am - 11:06 pmDSM-GYE
16h 06m1 stop
American Airlines Logo
6:10 am - 11:29 pmGYE-DSM
18h 19m1 stop
$1,086American Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6

United Airlines flights from Des Moines to Guayaquil

Our best United Airlines deals on Des Moines to Guayaquil flight tickets
United Airlines
Nov 28
DSM6:05 amDes Moines
16h 36m
2 stops
GYE11:41 pmGuayaquil Jose Joaquin de Olmedo
Dec 5
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
32h 54m
2 stops
DSM10:29 pmDes Moines
$662
Find similar
United Airlines
Nov 29
DSM6:05 amDes Moines
16h 36m
2 stops
GYE11:41 pmGuayaquil Jose Joaquin de Olmedo
Dec 6
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
14h 59m
2 stops
DSM10:29 pmDes Moines
$721
Find similar

American Airlines flights from Des Moines to Guayaquil

Our best American Airlines deals on Des Moines to Guayaquil flight tickets
American Airlines
Nov 28
DSM5:26 pmDes Moines
28h 40m
2 stops
GYE11:06 pmGuayaquil Jose Joaquin de Olmedo
Dec 5
GYE6:10 amGuayaquil Jose Joaquin de Olmedo
18h 19m
1 stop
DSM11:29 pmDes Moines
$790
Find similar
American Airlines
Nov 29
DSM5:42 amDes Moines
16h 24m
2 stops
GYE11:06 pmGuayaquil Jose Joaquin de Olmedo
Dec 6
GYE6:10 amGuayaquil Jose Joaquin de Olmedo
18h 19m
1 stop
DSM11:29 pmDes Moines
$847
Find similar
American Airlines
Nov 28
DSM6:00 amDes Moines
16h 06m
1 stop
GYE11:06 pmGuayaquil Jose Joaquin de Olmedo
Dec 5
GYE6:10 amGuayaquil Jose Joaquin de Olmedo
18h 19m
1 stop
DSM11:29 pmDes Moines
$999
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Des Moines to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 11/28

6:05 am-11:41 pm

2 stops16h 36m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

2:35 pm-10:29 pm

2 stops32h 54m

$662

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

6:05 am-11:41 pm

2 stops16h 36m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

8:30 am-10:29 pm

2 stops14h 59m

$721

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

10:55 am-5:38 pm

3 stops29h 43m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

6:55 pm-10:21 pm

2 stops28h 26m

$788

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 11/28

5:26 pm-11:06 pm

2 stops28h 40m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

6:10 am-11:29 pm

1 stop18h 19m

$790

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

5:42 am-11:06 pm

2 stops16h 24m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

6:10 am-11:29 pm

1 stop18h 19m

$847

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

10:55 am-11:41 pm

2 stops11h 46m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

4:40 am-10:21 pm

3 stops42h 41m

$906

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

10:55 am-5:38 pm

3 stops29h 43m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

9:05 am-10:21 pm

3 stops38h 16m

$939

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 11/28

6:00 am-11:06 pm

1 stop16h 06m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

6:10 am-11:29 pm

1 stop18h 19m

$999

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 11/29

6:00 am-11:06 pm

1 stop16h 06m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

6:10 am-11:29 pm

1 stop18h 19m

$1,086

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Des Moines to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Des Moines to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $476. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $925.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $693. Flights to Guayaquil are more costly in the afternoon, with an average ticket price of $767. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Des Moines to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Guayaquil (DSM to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guayaquil

Direct flights

None
There are no direct flights from Des Moines to Guayaquil. There are no popular flight routes from Des Moines to Guayaquil.
Search flight deals

  • How far is Des Moines to Guayaquil Jose Joaquin de Olmedo by plane?

    Des Moines and Guayaquil Jose Joaquin de Olmedo are 3143.1 mi apart from one another. Flights usually cover this in 11h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from Des Moines.

Can I find flights from Des Moines to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Guayaquil?

momondo helps you find the best flight between Des Moines and Guayaquil by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Guayaquil right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Guayaquil flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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