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Cheap flights from Des Moines to Guayaquil from $426

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guayaquil departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:56 am - 9:12 pm
DSM
-
GYE
12h 16m
2 stops
American Airlines Logo
6:05 am - 11:49 pm
GYE
-
DSM
17h 44m
2 stops
$718American Airlines
Fri, May 1 - Fri, May 8
American Airlines Logo
6:00 am - 9:12 pm
DSM
-
GYE
15h 12m
2 stops
American Airlines Logo
6:05 am - 9:54 pm
GYE
-
DSM
15h 49m
2 stops
$727American Airlines
Sat, May 2 - Sat, May 9
United Airlines Logo
8:20 am - 5:31 pm
DSM
-
GYE
33h 11m
2 stops
United Airlines Logo
2:43 pm - 2:17 pm
GYE
-
DSM
47h 34m
2 stops
$840United Airlines
Mon, Apr 27 - Thu, Apr 30
American Airlines Logo
1:41 pm - 1:34 pm
DSM
-
GYE
23h 53m
2 stops
American Airlines Logo
8:00 am - 11:55 pm
GYE
-
DSM
15h 55m
2 stops
$890American Airlines
Fri, Jul 31 - Mon, Aug 17
United Airlines Logo
8:20 am - 5:31 pm
DSM
-
GYE
33h 11m
2 stops
United Airlines Logo
8:28 am - 2:17 pm
GYE
-
DSM
29h 49m
2 stops
$898United Airlines
Mon, Apr 27 - Thu, Apr 30

United Airlines flights from Des Moines to Guayaquil

Our best United Airlines deals on Des Moines to Guayaquil flight tickets
United Airlines
Apr 27
DSM8:20 amDes Moines
33h 11m
2 stops
GYE5:31 pmGuayaquil Jose Joaquin de Olmedo
Apr 30
GYE2:43 pmGuayaquil Jose Joaquin de Olmedo
47h 34m
2 stops
DSM2:17 pmDes Moines
$840
United Airlines
Apr 27
DSM8:20 amDes Moines
33h 11m
2 stops
GYE5:31 pmGuayaquil Jose Joaquin de Olmedo
Apr 30
GYE8:28 amGuayaquil Jose Joaquin de Olmedo
29h 49m
2 stops
DSM2:17 pmDes Moines
$898

American Airlines flights from Des Moines to Guayaquil

Our best American Airlines deals on Des Moines to Guayaquil flight tickets
American Airlines
May 1
DSM8:56 amDes Moines
12h 16m
2 stops
GYE9:12 pmGuayaquil Jose Joaquin de Olmedo
May 8
GYE6:05 amGuayaquil Jose Joaquin de Olmedo
17h 44m
2 stops
DSM11:49 pmDes Moines
$718
American Airlines
May 2
DSM6:00 amDes Moines
15h 12m
2 stops
GYE9:12 pmGuayaquil Jose Joaquin de Olmedo
May 9
GYE6:05 amGuayaquil Jose Joaquin de Olmedo
15h 49m
2 stops
DSM9:54 pmDes Moines
$727
American Airlines
Jul 31
DSM1:41 pmDes Moines
23h 53m
2 stops
GYE1:34 pmGuayaquil Jose Joaquin de Olmedo
Aug 17
GYE8:00 amGuayaquil Jose Joaquin de Olmedo
15h 55m
2 stops
DSM11:55 pmDes Moines
$890

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Des Moines to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 5/1

8:56 am-9:12 pm

2 stops12h 16m

Guayaquil Jose Joaquin de Olmedo

Fri 5/8

6:05 am-11:49 pm

2 stops17h 44m

$718

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 5/2

6:00 am-9:12 pm

2 stops15h 12m

Guayaquil Jose Joaquin de Olmedo

Sat 5/9

6:05 am-9:54 pm

2 stops15h 49m

$727

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 4/27

8:20 am-5:31 pm

2 stops33h 11m

Guayaquil Jose Joaquin de Olmedo

Thu 4/30

2:43 pm-2:17 pm

2 stops47h 34m

$840

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 7/31

1:41 pm-1:34 pm

2 stops23h 53m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

8:00 am-11:55 pm

2 stops15h 55m

$890

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 4/27

8:20 am-5:31 pm

2 stops33h 11m

Guayaquil Jose Joaquin de Olmedo

Thu 4/30

8:28 am-2:17 pm

2 stops29h 49m

$898
Cheapest one-way
Quickest one-way

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 8/5

6:00 am-7:37 pm

2 stops13h 37m

$426

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 8/5

6:00 am-7:37 pm

2 stops13h 37m

$428

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 8/5

6:00 am-7:37 pm

2 stops13h 37m

$429

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 8/5

6:00 am-7:37 pm

2 stops13h 37m

$430

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 8/5

6:00 am-8:53 pm

3 stops38h 53m

$616

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Des Moines to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Guayaquil Jose Joaquin de Olmedo?

United Airlines is the most popular carrier operating from Des Moines to Guayaquil Jose Joaquin de Olmedo

When to book flights from Des Moines to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Guayaquil (DSM to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guayaquil

Fastest flight time

16h 35m

Direct flights

None
The fastest flight from Des Moines to Guayaquil takes 16h 35m
There are no direct flights from Des Moines to Guayaquil. There are no popular flight routes from Des Moines to Guayaquil.
Search flight deals

  • How far is Des Moines to Guayaquil Jose Joaquin de Olmedo by plane?

    Des Moines and Guayaquil Jose Joaquin de Olmedo are 3143.1 mi apart from one another. Flights usually cover this in 16h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from Des Moines.

Can I find flights from Des Moines to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Guayaquil?

momondo helps you find the best flight between Des Moines and Guayaquil by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Guayaquil right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Guayaquil flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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