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Cheap flights from Des Moines to Guayaquil from $611

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guayaquil departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Guayaquil

Cheap round-trip flights

United Airlines Logo
6:15 am - 11:37 pmDSM-GYE
17h 22m2 stops
United Airlines Logo
8:30 am - 10:28 pmGYE-DSM
37h 58m2 stops
$611United Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Logo
6:15 am - 1:46 pmDSM-GYE
31h 31m2 stops
Logo
3:35 am - 2:13 pmGYE-DSM
34h 38m2 stops
$633
Find Deal
Wed, Oct 15 - Sun, Oct 19
United Airlines Logo
6:15 am - 11:15 amDSM-GYE
29h 00m2 stops
United Airlines Logo
2:44 pm - 10:28 pmGYE-DSM
31h 44m2 stops
$635United Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 20
United Airlines Logo
6:15 am - 2:05 amDSM-GYE
19h 50m2 stops
United Airlines Logo
12:15 pm - 10:28 pmGYE-DSM
34h 13m2 stops
$636United Airlines
Find Deal
Mon, Oct 13 - Tue, Oct 21
United Airlines Logo
6:15 am - 2:05 amDSM-GYE
19h 50m2 stops
United Airlines Logo
8:30 am - 10:28 pmGYE-DSM
37h 58m2 stops
$645United Airlines
Find Deal
Thu, Oct 16 - Tue, Oct 21
United Airlines Logo
6:15 am - 1:46 pmDSM-GYE
31h 31m2 stops
United Airlines Logo
12:15 pm - 10:28 pmGYE-DSM
34h 13m2 stops
$658United Airlines
Find Deal
Sun, Oct 12 - Tue, Oct 21
United Airlines Logo
6:15 am - 2:05 amDSM-GYE
19h 50m2 stops
United Airlines Logo
2:44 pm - 10:28 pmGYE-DSM
31h 44m2 stops
$670United Airlines
Find Deal
Tue, Oct 14 - Sun, Oct 19
United Airlines Logo
6:15 am - 2:05 amDSM-GYE
19h 50m2 stops
United Airlines Logo
2:44 pm - 10:28 pmGYE-DSM
31h 44m2 stops
$680United Airlines
Find Deal
Thu, Oct 16 - Sun, Oct 19
Logo
6:15 am - 12:25 pmDSM-GYE
30h 10m2 stops
Logo
3:35 am - 10:28 pmGYE-DSM
18h 53m2 stops
$687
Find Deal
Tue, Oct 14 - Sat, Oct 18
Avianca Logo
8:00 am - 1:40 pmDSM-GYE
29h 40m2 stops
Avianca Logo
3:35 am - 9:45 pmGYE-DSM
18h 10m2 stops
$1,441Avianca
Find Deal
Sun, Sep 14 - Sat, Sep 20

United Airlines flights from Des Moines to Guayaquil

Our best United Airlines deals on Des Moines to Guayaquil flight tickets
United Airlines
Oct 14
DSM6:15 amDes Moines
17h 22m
2 stops
GYE11:37 pmGuayaquil Jose Joaquin de Olmedo
Oct 21
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
37h 58m
2 stops
DSM10:28 pmDes Moines
$611
Find similar
United Airlines
Oct 15
DSM6:15 amDes Moines
29h 00m
2 stops
GYE11:15 amGuayaquil Jose Joaquin de Olmedo
Oct 20
GYE2:44 pmGuayaquil Jose Joaquin de Olmedo
31h 44m
2 stops
DSM10:28 pmDes Moines
$635
Find similar
United Airlines
Oct 13
DSM6:15 amDes Moines
19h 50m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
Oct 21
GYE12:15 pmGuayaquil Jose Joaquin de Olmedo
34h 13m
2 stops
DSM10:28 pmDes Moines
$636
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Des Moines to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Tue 10/14

6:15 am-11:37 pm

2 stops17h 22m

Guayaquil Jose Joaquin de Olmedo

Tue 10/21

8:30 am-10:28 pm

2 stops37h 58m

$611

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 10/15

6:15 am-1:46 pm

2 stops31h 31m

Guayaquil Jose Joaquin de Olmedo

Sun 10/19

3:35 am-2:13 pm

2 stops34h 38m

$633

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 10/15

6:15 am-11:15 am

2 stops29h 00m

Guayaquil Jose Joaquin de Olmedo

Mon 10/20

2:44 pm-10:28 pm

2 stops31h 44m

$635

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 10/13

6:15 am-2:05 am

2 stops19h 50m

Guayaquil Jose Joaquin de Olmedo

Tue 10/21

12:15 pm-10:28 pm

2 stops34h 13m

$636

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Thu 10/16

6:15 am-2:05 am

2 stops19h 50m

Guayaquil Jose Joaquin de Olmedo

Tue 10/21

8:30 am-10:28 pm

2 stops37h 58m

$645

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 10/12

6:15 am-1:46 pm

2 stops31h 31m

Guayaquil Jose Joaquin de Olmedo

Tue 10/21

12:15 pm-10:28 pm

2 stops34h 13m

$658

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Tue 10/14

6:15 am-2:05 am

2 stops19h 50m

Guayaquil Jose Joaquin de Olmedo

Sun 10/19

2:44 pm-10:28 pm

2 stops31h 44m

$670

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Thu 10/16

6:15 am-2:05 am

2 stops19h 50m

Guayaquil Jose Joaquin de Olmedo

Sun 10/19

2:44 pm-10:28 pm

2 stops31h 44m

$680

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Tue 10/14

6:15 am-12:25 pm

2 stops30h 10m

Guayaquil Jose Joaquin de Olmedo

Sat 10/18

3:35 am-10:28 pm

2 stops18h 53m

$687

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 9/14

8:00 am-1:40 pm

2 stops29h 40m

Guayaquil Jose Joaquin de Olmedo

Sat 9/20

3:35 am-9:45 pm

2 stops18h 10m

$1,441

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Des Moines to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Des Moines to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $476. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $925.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $693. Flights to Guayaquil are more costly in the afternoon, with an average ticket price of $767. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Des Moines to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Guayaquil (DSM to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guayaquil

Best Price Found

$611

Fastest flight time

17h 22m

Direct flights

None

Airports in Guayaquil

1 airport
The best flight deal from Des Moines to Guayaquil found on momondo in the last 72 hours is $611
The fastest flight from Des Moines to Guayaquil takes 17h 22m
There are no direct flights from Des Moines to Guayaquil. Popular non-direct route for this connection is Des Moines Airport - Guayaquil Jose Joaquin de Olmedo Airport.
There is 1 airport near Guayaquil: Guayaquil Jose Joaquin de Olmedo (GYE)
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  • How far is Des Moines to Guayaquil Jose Joaquin de Olmedo by plane?

    Des Moines and Guayaquil Jose Joaquin de Olmedo are 3143.1 mi apart from one another. Flights usually cover this in 17h 22m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Guayaquil?

Best airlines flying from Des Moines to Guayaquil

Compare and see reviews for airlines that fly from Des Moines to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $609Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from Des Moines.

Can I find flights from Des Moines to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Guayaquil?

momondo helps you find the best flight between Des Moines and Guayaquil by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Guayaquil right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Guayaquil flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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