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Cheap flights from Des Moines to the Czech Republic from $656

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 3/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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United Airlines Logo
8:00 am - 10:50 amDSM-PRG
20h 50m2 stops
United Airlines Logo
6:00 am - 5:33 pmPRG-DSM
18h 33m2 stops
$656United Airlines
Find Deal
Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
3:15 pm - 10:50 amDSM-PRG
13h 35m2 stops
United Airlines Logo
6:00 am - 9:36 pmPRG-DSM
22h 36m2 stops
$657United Airlines
Find Deal
Fri, Mar 27 - Tue, Mar 31
Lufthansa Logo
11:30 am - 4:05 pmDSM-PRG
21h 35m2 stops
Lufthansa Logo
6:10 am - 9:36 pmPRG-DSM
22h 26m2 stops
$688Lufthansa
Find Deal
Fri, May 1 - Sun, May 10
United Airlines Logo
3:15 pm - 2:05 pmDSM-PRG
15h 50m2 stops
United Airlines Logo
3:00 pm - 10:45 amPRG-DSM
25h 45m2 stops
$719United Airlines
Find Deal
Fri, Mar 6 - Sun, Mar 8
Multiple Airlines Logo
6:17 am - 8:25 amDSM-PRG
19h 08m2 stops
Multiple Airlines Logo
11:35 am - 8:44 pmPRG-DSM
16h 09m2 stops
$791Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23
Multiple Airlines Logo
10:20 am - 8:25 amDSM-PRG
15h 05m2 stops
Multiple Airlines Logo
2:30 pm - 8:02 pmPRG-DSM
36h 32m2 stops
$815Multiple Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
American Airlines Logo
6:33 am - 11:00 amDSM-PRG
21h 27m2 stops
American Airlines Logo
10:55 am - 9:52 pmPRG-DSM
16h 57m2 stops
$858American Airlines
Find Deal
Fri, Mar 6 - Sun, Mar 8
Air Canada Logo
11:35 am - 1:05 pmDSM-PRG
18h 30m3 stops
Air Canada Logo
7:25 am - 9:40 pmPRG-DSM
21h 15m3 stops
$1,404Air Canada
Find Deal
Tue, Dec 16 - Tue, Dec 23
Air Canada Logo
11:35 am - 1:05 pmDSM-PRG
18h 30m3 stops
Air Canada Logo
7:25 am - 9:40 pmPRG-DSM
21h 15m3 stops
$1,405Air Canada
Find Deal
Tue, Dec 16 - Tue, Dec 23
Lufthansa Logo
6:46 pm - 6:15 pmDSM-PRG
16h 29m2 stops
Lufthansa Logo
1:45 pm - 9:40 pmPRG-DSM
14h 55m2 stops
$1,787Lufthansa
Find Deal
Fri, Dec 19 - Sat, Dec 27

United Airlines flights from Des Moines to Czech Republic

Our best United Airlines deals on Des Moines to Czech Republic flight tickets
United Airlines
Mar 27
DSM8:00 amDes Moines
20h 50m
2 stops
PRG10:50 amVáclav Havel Prague
Mar 31
PRG6:00 amVáclav Havel Prague
18h 33m
2 stops
DSM5:33 pmDes Moines
$656
Find similar
United Airlines
Mar 27
DSM3:15 pmDes Moines
13h 35m
2 stops
PRG10:50 amVáclav Havel Prague
Mar 31
PRG6:00 amVáclav Havel Prague
22h 36m
2 stops
DSM9:36 pmDes Moines
$657
Find similar
United Airlines
Mar 6
DSM3:15 pmDes Moines
15h 50m
2 stops
PRG2:05 pmVáclav Havel Prague
Mar 8
PRG3:00 pmVáclav Havel Prague
25h 45m
2 stops
DSM10:45 amDes Moines
$719
Find similar

Lufthansa flights from Des Moines to Czech Republic

Our best Lufthansa deals on Des Moines to Czech Republic flight tickets
Lufthansa
May 1
DSM11:30 amDes Moines
21h 35m
2 stops
PRG4:05 pmVáclav Havel Prague
May 10
PRG6:10 amVáclav Havel Prague
22h 26m
2 stops
DSM9:36 pmDes Moines
$688
Find similar
Lufthansa
Dec 19
DSM6:46 pmDes Moines
16h 29m
2 stops
PRG6:15 pmVáclav Havel Prague
Dec 27
PRG1:45 pmVáclav Havel Prague
14h 55m
2 stops
DSM9:40 pmDes Moines
$1,787
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Des Moines to the Czech Republic that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 3/27

8:00 am-10:50 am

2 stops20h 50m

Václav Havel Prague

Tue 3/31

6:00 am-5:33 pm

2 stops18h 33m

$656

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 3/27

3:15 pm-10:50 am

2 stops13h 35m

Václav Havel Prague

Tue 3/31

6:00 am-9:36 pm

2 stops22h 36m

$657

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 5/1

11:30 am-4:05 pm

2 stops21h 35m

Václav Havel Prague

Sun 5/10

6:10 am-9:36 pm

2 stops22h 26m

$688

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 3/6

3:15 pm-2:05 pm

2 stops15h 50m

Václav Havel Prague

Sun 3/8

3:00 pm-10:45 am

2 stops25h 45m

$719

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/16

6:17 am-8:25 am

2 stops19h 08m

Václav Havel Prague

Tue 12/23

11:35 am-8:44 pm

2 stops16h 09m

$791

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Mon 12/15

10:20 am-8:25 am

2 stops15h 05m

Václav Havel Prague

Mon 12/22

2:30 pm-8:02 pm

2 stops36h 32m

$815

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 3/6

6:33 am-11:00 am

2 stops21h 27m

Václav Havel Prague

Sun 3/8

10:55 am-9:52 pm

2 stops16h 57m

$858

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/16

11:35 am-1:05 pm

3 stops18h 30m

Václav Havel Prague

Tue 12/23

7:25 am-9:40 pm

3 stops21h 15m

$1,404

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/16

11:35 am-1:05 pm

3 stops18h 30m

Václav Havel Prague

Tue 12/23

7:25 am-9:40 pm

3 stops21h 15m

$1,405

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/19

6:46 pm-6:15 pm

2 stops16h 29m

Václav Havel Prague

Sat 12/27

1:45 pm-9:40 pm

2 stops14h 55m

$1,787

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to the Czech Republic from

How to get the cheapest flight ticket from Des Moines to Czech Republic

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Czech Republic?

The cheapest day to depart from Des Moines to Czech Republic is on a Tuesday when prices can be found for as low as $816. The most expensive day to fly to Czech Republic is Friday, with ticket prices averaging around $1,811.

What is the cheapest time of day to depart on your flight to Czech Republic?

In the afternoon is the cheapest time of day to fly from Des Moines to Czech Republic when you can find flight prices for as low as $1,080. Flying to Czech Republic in the afternoon is an ideal time because this is during off-peak travel hours. Flights to Czech Republic are more costly in the morning, with an average ticket price of $1,157. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Des Moines to Czech Republic flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Czech Republic flight.

Cheap Des Moines to Czech Republic flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Czech Republic

Direct flights

None
There are no direct flights from Des Moines to Czech Republic. There are no popular flight routes from Des Moines to Czech Republic.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Czech Republic?

    Prices for flights from Des Moines Airport to Czech Republic are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Czech Republic?

  • How old do you have to be to fly from Des Moines Airport to Czech Republic?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Czech Republic.

  • What documentation or ID do you need to fly to Czech Republic?

    The travel and health documents required for your trip to Czech Republic can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Czech Republic. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Czech Republic

Compare and see reviews for airlines that fly from Des Moines to Czech Republic with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $597Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Czech Republic?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Czech Republic for you.

Can I find flights from Des Moines to Czech Republic with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Czech Republic flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Czech Republic?

momondo provides multiple filters to help you find the best flight to Czech Republic from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Czech Republic right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Czech Republic from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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