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Cheap flights from Des Moines to the Czech Republic from $434

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 8/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to the Czech Republic

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:21 pm - 8:55 am
DSM
-
PRG
12h 34m
2 stops
Multiple Airlines Logo
12:30 pm - 10:52 am
PRG
-
DSM
29h 22m
2 stops
$772Multiple Airlines
Wed, Aug 12 - Wed, Aug 19
United Airlines Logo
11:32 am - 8:55 am
DSM
-
PRG
14h 23m
2 stops
United Airlines Logo
12:30 pm - 12:20 pm
PRG
-
DSM
30h 50m
2 stops
$776United Airlines
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
1:55 pm - 1:15 pm
DSM
-
PRG
16h 20m
2 stops
American Airlines Logo
10:30 am - 10:06 pm
PRG
-
DSM
18h 36m
2 stops
$790American Airlines
Wed, Aug 12 - Wed, Aug 19
KLM Logo
5:30 pm - 5:40 pm
DSM
-
PRG
17h 10m
2 stops
KLM Logo
6:35 pm - 2:04 pm
PRG
-
DSM
26h 29m
2 stops
$792KLM
Tue, Aug 11 - Tue, Aug 18
Delta Logo
5:30 pm - 9:40 pm
DSM
-
PRG
21h 10m
2 stops
Delta Logo
2:30 pm - 2:04 pm
PRG
-
DSM
30h 34m
2 stops
$796Delta
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
7:49 pm - 5:05 pm
DSM
-
PRG
14h 16m
2 stops
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
$817American Airlines
Wed, Aug 12 - Wed, Aug 19
Lufthansa Logo
3:20 pm - 8:55 am
DSM
-
PRG
34h 35m
2 stops
Lufthansa Logo
4:40 pm - 9:23 pm
PRG
-
DSM
35h 43m
2 stops
$822Lufthansa
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
5:10 pm - 4:25 pm
DSM
-
PRG
16h 15m
2 stops
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
$830American Airlines
Tue, Aug 11 - Tue, Aug 18
Multiple Airlines Logo
10:59 am - 9:00 am
DSM
-
PRG
15h 01m
2 stops
Multiple Airlines Logo
6:00 am - 5:11 pm
PRG
-
DSM
18h 11m
2 stops
$831Multiple Airlines
Thu, Aug 13 - Thu, Aug 20
American Airlines Logo
1:07 pm - 8:15 am
DSM
-
PRG
12h 08m
1 stop
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
$833American Airlines
Thu, Aug 13 - Thu, Aug 20

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United Airlines flights from Des Moines to Czech Republic

Our best United Airlines deals on Des Moines to Czech Republic flight tickets
United Airlines
Aug 12
DSM11:32 amDes Moines
14h 23m
2 stops
PRG8:55 amVáclav Havel Prague
Aug 19
PRG12:30 pmVáclav Havel Prague
30h 50m
2 stops
DSM12:20 pmDes Moines
$776
United Airlines
Aug 15
DSM6:00 amDes Moines
45h 50m
3 stops
PRG10:50 amVáclav Havel Prague
Aug 22
PRG1:20 pmVáclav Havel Prague
52h 06m
2 stops
DSM10:26 amDes Moines
$867
United Airlines
Aug 14
DSM1:21 pmDes Moines
16h 19m
2 stops
PRG12:40 pmVáclav Havel Prague
Aug 23
PRG12:30 pmVáclav Havel Prague
34h 49m
2 stops
DSM4:19 pmDes Moines
$876

American Airlines flights from Des Moines to Czech Republic

Our best American Airlines deals on Des Moines to Czech Republic flight tickets
American Airlines
Aug 12
DSM1:55 pmDes Moines
16h 20m
2 stops
PRG1:15 pmVáclav Havel Prague
Aug 19
PRG10:30 amVáclav Havel Prague
18h 36m
2 stops
DSM10:06 pmDes Moines
$790
American Airlines
Aug 12
DSM7:49 pmDes Moines
14h 16m
2 stops
PRG5:05 pmVáclav Havel Prague
Aug 19
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
$817
American Airlines
Aug 11
DSM5:10 pmDes Moines
16h 15m
2 stops
PRG4:25 pmVáclav Havel Prague
Aug 18
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
$830

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Des Moines to the Czech Republic that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

1:21 pm-8:55 am

2 stops12h 34m

Václav Havel Prague

Wed 8/19

12:30 pm-10:52 am

2 stops29h 22m

$772

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

11:32 am-8:55 am

2 stops14h 23m

Václav Havel Prague

Wed 8/19

12:30 pm-12:20 pm

2 stops30h 50m

$776

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

1:55 pm-1:15 pm

2 stops16h 20m

Václav Havel Prague

Wed 8/19

10:30 am-10:06 pm

2 stops18h 36m

$790

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 8/11

5:30 pm-5:40 pm

2 stops17h 10m

Václav Havel Prague

Tue 8/18

6:35 pm-2:04 pm

2 stops26h 29m

$792

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

5:30 pm-9:40 pm

2 stops21h 10m

Václav Havel Prague

Wed 8/19

2:30 pm-2:04 pm

2 stops30h 34m

$796

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

7:49 pm-5:05 pm

2 stops14h 16m

Václav Havel Prague

Wed 8/19

10:15 am-10:06 pm

1 stop18h 51m

$817

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sat 8/15

3:20 pm-8:55 am

2 stops34h 35m

Václav Havel Prague

Sat 8/22

4:40 pm-9:23 pm

2 stops35h 43m

$822

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 8/11

5:10 pm-4:25 pm

2 stops16h 15m

Václav Havel Prague

Tue 8/18

10:15 am-10:06 pm

1 stop18h 51m

$830

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/13

10:59 am-9:00 am

2 stops15h 01m

Václav Havel Prague

Thu 8/20

6:00 am-5:11 pm

2 stops18h 11m

$831
Quickest round-trip

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/13

1:07 pm-8:15 am

1 stop12h 08m

Václav Havel Prague

Thu 8/20

10:15 am-10:06 pm

1 stop18h 51m

$833

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to the Czech Republic from

How to get the cheapest flight ticket from Des Moines to Czech Republic

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Czech Republic flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Czech Republic flight.

Cheap Des Moines to Czech Republic flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Czech Republic

Fastest flight time

12h 34m

Direct flights

None
The fastest flight from Des Moines to Czech Republic takes 12h 34m
There are no direct flights from Des Moines to Czech Republic. There are no popular flight routes from Des Moines to Czech Republic.
Search flight deals

Frequently asked questions about flying from Des Moines to the Czech Republic

  • When did momondo last update prices for flights from Des Moines Airport to Czech Republic?

    Prices for flights from Des Moines Airport to Czech Republic are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Czech Republic?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Czech Republic.

  • What documentation or ID do you need to fly to Czech Republic?

    The travel and health documents required for your trip to Czech Republic can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Czech Republic. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Czech Republic?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Czech Republic for you.

Can I find flights from Des Moines to Czech Republic with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Czech Republic flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Czech Republic?

momondo provides multiple filters to help you find the best flight to Czech Republic from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Czech Republic right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Czech Republic from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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