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Cheap flights from Denver to Panama from $202

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:49 pm - 8:37 pm
DEN
-
PTY
19h 48m
1 stop
Multiple Airlines Logo
10:05 pm - 8:00 pm
PTY
-
DEN
22h 55m
2 stops
$504Multiple Airlines
Wed, Apr 1 - Fri, Apr 10
Multiple Airlines Logo
6:00 am - 8:50 am
DEN
-
PTY
25h 50m
2 stops
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$520Multiple Airlines
Sun, Mar 8 - Mon, Mar 16
Multiple Airlines Logo
7:35 am - 2:00 pm
DEN
-
PTY
29h 25m
2 stops
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$521Multiple Airlines
Tue, Mar 10 - Mon, Mar 16
Multiple Airlines Logo
6:00 am - 8:50 am
DEN
-
PTY
25h 50m
2 stops
Multiple Airlines Logo
10:26 am - 11:04 pm
PTY
-
DEN
13h 38m
1 stop
$528Multiple Airlines
Sun, Mar 8 - Tue, Mar 17
Multiple Airlines Logo
4:38 pm - 1:00 am
DEN
-
PTY
31h 22m
2 stops
Multiple Airlines Logo
9:33 pm - 9:40 am
PTY
-
DEN
13h 07m
1 stop
$529Multiple Airlines
Mon, Mar 9 - Tue, Mar 31
Multiple Airlines Logo
4:38 pm - 1:00 am
DEN
-
PTY
31h 22m
2 stops
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$539Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Avianca Logo
8:11 pm - 10:30 am
DEN
-
PTY
13h 19m
2 stops
Avianca Logo
3:50 pm - 6:15 pm
PTY
-
DEN
27h 25m
2 stops
$541Avianca
Mon, Apr 27 - Fri, May 1
Multiple Airlines Logo
11:35 am - 6:55 pm
DEN
-
PTY
29h 20m
2 stops
Multiple Airlines Logo
3:50 pm - 10:50 am
PTY
-
DEN
21h 00m
2 stops
$543Multiple Airlines
Tue, Feb 3 - Sun, Feb 8
Multiple Airlines Logo
5:59 pm - 6:55 pm
DEN
-
PTY
22h 56m
2 stops
Multiple Airlines Logo
3:50 pm - 10:50 am
PTY
-
DEN
21h 00m
2 stops
$545Multiple Airlines
Sat, Jan 31 - Sun, Feb 8
Multiple Airlines Logo
11:25 pm - 4:06 pm
DEN
-
PTY
14h 41m
1 stop
Multiple Airlines Logo
7:50 pm - 9:11 am
PTY
-
DEN
39h 21m
2 stops
$546Multiple Airlines
Sat, Feb 14 - Sun, Mar 1

American Airlines flights from Denver to Panama

Our best American Airlines deals on Denver to Panama flight tickets
American Airlines
Apr 19
DEN2:13 pmDenver Intl
21h 23m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 25
PTY1:49 pmPanama City Tocumen Intl
23h 20m
2 stops
DEN12:09 pmDenver Intl
$575
American Airlines
May 13
DEN11:30 pmDenver Intl
12h 06m
1 stop
PTY12:36 pmPanama City Tocumen Intl
May 17
PTY1:49 pmPanama City Tocumen Intl
19h 37m
2 stops
DEN8:26 amDenver Intl
$580
American Airlines
Apr 9
DEN3:59 pmDenver Intl
19h 37m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 19
PTY1:49 pmPanama City Tocumen Intl
21h 07m
2 stops
DEN9:56 amDenver Intl
$587

Copa Airlines flights from Denver to Panama

Our best Copa Airlines deals on Denver to Panama flight tickets
Copa Airlines
May 13
DEN10:51 pmDenver Intl
5h 42m
PTY5:33 amPanama City Tocumen Intl
May 17
PTY12:56 pmPanama City Tocumen Intl
6h 29m
DEN6:25 pmDenver Intl
$571
Copa Airlines
Apr 27
DEN10:51 pmDenver Intl
5h 42m
PTY5:33 amPanama City Tocumen Intl
May 2
PTY12:56 pmPanama City Tocumen Intl
6h 29m
DEN6:25 pmDenver Intl
$576
Copa Airlines
Mar 21
DEN9:06 pmDenver Intl
15h 39m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Mar 26
PTY3:41 pmPanama City Tocumen Intl
15h 59m
1 stop
DEN6:40 amDenver Intl
$582

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/1

11:49 pm-8:37 pm

1 stop19h 48m

Panama City Tocumen Intl

Fri 4/10

10:05 pm-8:00 pm

2 stops22h 55m

$504

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 3/8

6:00 am-8:50 am

2 stops25h 50m

Panama City Tocumen Intl

Mon 3/16

9:33 pm-8:26 am

1 stop11h 53m

$520

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/10

7:35 am-2:00 pm

2 stops29h 25m

Panama City Tocumen Intl

Mon 3/16

9:33 pm-8:26 am

1 stop11h 53m

$521

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 3/8

6:00 am-8:50 am

2 stops25h 50m

Panama City Tocumen Intl

Tue 3/17

10:26 am-11:04 pm

1 stop13h 38m

$528

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 3/9

4:38 pm-1:00 am

2 stops31h 22m

Panama City Tocumen Intl

Tue 3/31

9:33 pm-9:40 am

1 stop13h 07m

$529

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 3/9

4:38 pm-1:00 am

2 stops31h 22m

Panama City Tocumen Intl

Mon 3/16

9:33 pm-8:26 am

1 stop11h 53m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 4/27

8:11 pm-10:30 am

2 stops13h 19m

Panama City Tocumen Intl

Fri 5/1

3:50 pm-6:15 pm

2 stops27h 25m

$541

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 2/3

11:35 am-6:55 pm

2 stops29h 20m

Panama City Tocumen Intl

Sun 2/8

3:50 pm-10:50 am

2 stops21h 00m

$543

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/31

5:59 pm-6:55 pm

2 stops22h 56m

Panama City Tocumen Intl

Sun 2/8

3:50 pm-10:50 am

2 stops21h 00m

$545

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/14

11:25 pm-4:06 pm

1 stop14h 41m

Panama City Tocumen Intl

Sun 3/1

7:50 pm-9:11 am

2 stops39h 21m

$546

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Denver to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Denver, with most prices found around $550. If you don’t want to visit Panama in August, then you should wait until May to fly from Denver, when ticket prices are also cheap, with an average price of $551.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Denver. The lowest ticket price found for a Tuesday departure recently was $519. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Panama for around $620.

What is the cheapest Denver Intl to Panama flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $634 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Denver for as low as $558 on momondo.

What cabin class options are available on Denver Intl to Panama flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama flights?

You could potentially save up to 18% on your flight if you consider stops on a Denver to Panama flight.

Cheap Denver to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama

Best Price Found

$262

Fastest flight time

5h 41m

Direct flights

Every day

Airports in Panama

21 airports
The best one-way flight to Panama from Denver in the past 72 hours is $262. The best round-trip flight deal from Denver to Panama found on momondo in the last 72 hours is $444.
The fastest flight from Denver to Panama takes 5h 41m
Direct flights go from Denver to Panama every day.
There are 21 airports in Panama. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • When did momondo last update prices for flights from Denver Intl Airport to Panama?

    Prices for flights from Denver Intl Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama?

  • How old do you have to be to fly from Denver Intl Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama?

Best airlines flying from Denver to Panama

Compare and see reviews for airlines that fly from Denver to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $456Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $473Free CancellationRating
7.2
11,168 reviews
Search American Airlines flights
DeltaPriceFrom $527Free CancellationRating
7.9
8,087 reviews
Search Delta flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,189 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Panama with flexible booking policies on momondo?

Flights from Denver to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to Panama?

momondo helps you find the best flight between Denver and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Denver and alert you when they change.

An easier way to manage your Panama trip

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