What airlines fly to Panama?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama from Denver according to our data. Copa Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How many flights depart from Denver to Panama on average per day?

The number of flights available between Denver and Panama is 1 per day as of November 2025. The most frequent departure time is 9:00PM, with 100% of daily flights leaving in the evening.

How many flights depart from Denver to Panama on average per week?

As of November 2025, 10 flights take off from Denver and land in Panama each week. The most common flight departure day for this route is Wed, with 20% of weekly flights taking off on this day.

When did momondo last update prices for flights from Denver Intl Airport to Panama?

Prices for flights from Denver Intl Airport to Panama were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Panama?

There are 4 operators available for flights from Denver Intl Airport to Panama as of November 2025.

How old do you have to be to fly from Denver Intl Airport to Panama?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$255 Cheap Flights from Denver to Panama in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Denver to Panama

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:38 pm - 5:33 amDEN-PTY

5h 55mnonstop

12:56 pm - 5:16 pmPTY-DEN

6h 20mnonstop

$548Copa Airlines

Find Deal

sáb., ene. 17 - mié., ene. 28

9:06 pm - 4:07 pmDEN-PTY

18h 01m1 stop

3:30 pm - 11:48 pmPTY-DEN

9h 18m1 stop

$550United Airlines

Find Deal

sáb., mar. 21 - lun., mar. 30

3:17 pm - 1:27 pmDEN-PTY

20h 10m2 stops

4:50 pm - 12:02 pmPTY-DEN

21h 12m2 stops

$552American Airlines

Find Deal

lun., ene. 26 - lun., feb. 2

5:58 pm - 2:22 pmDEN-PTY

19h 24m2 stops

1:39 pm - 11:40 amPTY-DEN

23h 01m2 stops

$554American Airlines

Find Deal

mié., mar. 11 - lun., mar. 16

11:26 pm - 1:50 pmDEN-PTY

12h 24m1 stop

2:50 pm - 11:59 pmPTY-DEN

11h 09m1 stop

$557American Airlines

Find Deal

vie., feb. 20 - mar., feb. 24

11:26 pm - 3:15 pmDEN-PTY

13h 49m1 stop

1:44 pm - 8:20 amPTY-DEN

19h 36m2 stops

$559American Airlines

Find Deal

vie., feb. 27 - dom., mar. 8

3:59 pm - 1:50 pmDEN-PTY

19h 51m2 stops

2:50 pm - 9:30 amPTY-DEN

20h 40m2 stops

$561American Airlines

Find Deal

vie., feb. 20 - sáb., feb. 28

12:30 am - 1:55 pmDEN-PTY

11h 25m1 stop

3:20 pm - 10:50 pmPTY-DEN

9h 30m1 stop

$563Delta

Find Deal

lun., ene. 19 - mar., ene. 27

11:59 pm - 10:40 amDEN-PTY

8h 41m1 stop

9:33 pm - 12:19 pmPTY-DEN

16h 46m2 stops

$564Multiple Airlines

Find Deal

vie., ene. 16 - vie., ene. 23

5:29 pm - 1:27 pmDEN-PTY

17h 58m2 stops

5:00 pm - 12:02 pmPTY-DEN

21h 02m2 stops

$567American Airlines

Find Deal

mar., ene. 13 - sáb., ene. 17

American Airlines flights from Denver to Panama

Our best American Airlines deals on Denver to Panama flight tickets

American Airlines

Jan 26

DEN3:17 pmDenver Intl

20h 10m

2 stops

PTY1:27 pmPanama City Tocumen Intl

Feb 2

PTY4:50 pmPanama City Tocumen Intl

21h 12m

2 stops

DEN12:02 pmDenver Intl

$552

Find similar

American Airlines

Mar 11

DEN5:58 pmDenver Intl

19h 24m

2 stops

PTY2:22 pmPanama City Tocumen Intl

Mar 16

PTY1:39 pmPanama City Tocumen Intl

23h 01m

2 stops

DEN11:40 amDenver Intl

$554

Find similar

American Airlines

Feb 20

DEN11:26 pmDenver Intl

12h 24m

1 stop

PTY1:50 pmPanama City Tocumen Intl

Feb 24

PTY2:50 pmPanama City Tocumen Intl

11h 09m

1 stop

DEN11:59 pmDenver Intl

$557

Find similar

Copa Airlines flights from Denver to Panama

Our best Copa Airlines deals on Denver to Panama flight tickets

Copa Airlines

Jan 17

DEN9:38 pmDenver Intl

5h 55m

PTY5:33 amPanama City Tocumen Intl

Jan 28

PTY12:56 pmPanama City Tocumen Intl

6h 20m

DEN5:16 pmDenver Intl

$548

Find similar

Copa Airlines

Jan 13

DEN9:38 pmDenver Intl

5h 55m

PTY5:33 amPanama City Tocumen Intl

Jan 22

PTY12:56 pmPanama City Tocumen Intl

6h 20m

DEN5:16 pmDenver Intl

$574

Find similar

Copa Airlines

Jan 26

DEN9:38 pmDenver Intl

5h 55m

PTY5:33 amPanama City Tocumen Intl

Jan 28

PTY12:56 pmPanama City Tocumen Intl

6h 20m

DEN5:16 pmDenver Intl

$596

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

sáb. 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

mié. 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

sáb. 3/21

9:06 pm-4:07 pm

1 stop18h 01m

Panama City Tocumen Intl

lun. 3/30

3:30 pm-11:48 pm

1 stop9h 18m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

lun. 1/26

3:17 pm-1:27 pm

2 stops20h 10m

Panama City Tocumen Intl

lun. 2/2

4:50 pm-12:02 pm

2 stops21h 12m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 3/11

5:58 pm-2:22 pm

2 stops19h 24m

Panama City Tocumen Intl

lun. 3/16

1:39 pm-11:40 am

2 stops23h 01m

$554

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 2/20

11:26 pm-1:50 pm

1 stop12h 24m

Panama City Tocumen Intl

mar. 2/24

2:50 pm-11:59 pm

1 stop11h 09m

$557

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 2/27

11:26 pm-3:15 pm

1 stop13h 49m

Panama City Tocumen Intl

dom. 3/8

1:44 pm-8:20 am

2 stops19h 36m

$559

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 2/20

3:59 pm-1:50 pm

2 stops19h 51m

Panama City Tocumen Intl

sáb. 2/28

2:50 pm-9:30 am

2 stops20h 40m

$561

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

lun. 1/19

12:30 am-1:55 pm

1 stop11h 25m

Panama City Tocumen Intl

mar. 1/27

3:20 pm-10:50 pm

1 stop9h 30m

$563

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 1/16

11:59 pm-10:40 am

1 stop8h 41m

Panama City Tocumen Intl

vie. 1/23

9:33 pm-12:19 pm

2 stops16h 46m

$564

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 1/13

5:29 pm-1:27 pm

2 stops17h 58m

Panama City Tocumen Intl

sáb. 1/17

5:00 pm-12:02 pm

2 stops21h 02m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Denver, with most prices found around $542. If you don’t want to visit Panama in August, then you should wait until May to fly from Denver, when ticket prices are also cheap, with an average price of $592.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Denver. The lowest ticket price found for a Tuesday departure recently was $484. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Panama for around $637.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Denver to Panama when you can find flight prices for as low as $599. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $733 per ticket.

What is the cheapest Denver Intl to Panama flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $652 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Denver for as low as $564 on momondo.

What cabin class options are available on Denver Intl to Panama flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama.

Cheap Denver to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama

Best Price Found	$197
Fastest flight time	5h 45m
Direct flights	Every day
Airports in Panama	1 airport

The best one-way flight to Panama from Denver in the past 72 hours is $197. The best round-trip flight deal from Denver to Panama found on momondo in the last 72 hours is $452.

The fastest flight from Denver to Panama takes 5h 45m

Direct flights go from Denver to Panama every day.

There is 1 airport near Panama: Panama City Tocumen Intl (PTY)

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to Panama?
Prices for flights from Denver Intl Airport to Panama were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Panama?
There are 4 operators available for flights from Denver Intl Airport to Panama as of November 2025.
How old do you have to be to fly from Denver Intl Airport to Panama?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Denver to Panama?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Denver to Panama is Boeing 737-800 (61.33% of total bookings). The next most popular plane models are Boeing 737 MAX 8 (33.70%), Boeing 737 MAX 9 (3.31%), and Boeing 737-900 (1.10%).

Best airlines flying from Denver to Panama

Compare and see reviews for airlines that fly from Denver to Panama with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $492	Free Cancellation	Rating 7.6 1,569 reviews	Search Copa Airlines flights
Delta	PriceFrom $527	Free Cancellation	Rating 7.9 7,998 reviews	Search Delta flights
American Airlines	PriceFrom $527	Free Cancellation	Rating 7.2 11,038 reviews	Search American Airlines flights
United Airlines	PriceFrom $527	Free Cancellation	Rating 7.4 9,046 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Panama with flexible booking policies on momondo?

Flights from Denver to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to Panama?

momondo helps you find the best flight between Denver and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Denver and alert you when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

vie. 12/26

vie. 1/2

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Flights to Panama Cityfrom $242

Flights to Bocas del Torofrom $631

Flights to Davidfrom $359

Flights to Changuinola

Cheap flights from Denver to Panama from $255

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama departing on 12/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Denver to Panama

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from Denver to Panama

Our best American Airlines deals on Denver to Panama flight tickets

Copa Airlines flights from Denver to Panama

Our best Copa Airlines deals on Denver to Panama flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Denver to Panama that are best for you.

See travel insights to Panama from

How to get the cheapest flight ticket from Denver to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Denver, with most prices found around $542. If you don’t want to visit Panama in August, then you should wait until May to fly from Denver, when ticket prices are also cheap, with an average price of $592.

What is the cheapest day to depart on your flight to Panama?

What is the cheapest time of day to depart on your flight to Panama?

What is the cheapest Denver Intl to Panama flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama flight prices

How far in advance should I book a flight to Panama?

What cabin class options are available on Denver Intl to Panama flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama.

What airlines fly to Panama?

How many flights depart from Denver to Panama on average per day?

The number of flights available between Denver and Panama is 1 per day as of November 2025. The most frequent departure time is 9:00PM, with 100% of daily flights leaving in the evening.

How many flights depart from Denver to Panama on average per week?

As of November 2025, 10 flights take off from Denver and land in Panama each week. The most common flight departure day for this route is Wed, with 20% of weekly flights taking off on this day.

Cheap Denver to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama

Best Price Found

Fastest flight time

Direct flights

Airports in Panama

When did momondo last update prices for flights from Denver Intl Airport to Panama?

How many operators does momondo search for flights from Denver Intl Airport to Panama?

How old do you have to be to fly from Denver Intl Airport to Panama?

What documentation or ID do you need to fly to Panama?

What is the most popular plane model from Denver to Panama?

Best airlines flying from Denver to Panama

Compare and see reviews for airlines that fly from Denver to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama?

Can I find flights from Denver to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Denver to Panama?

I’m not ready to book a flight from Denver to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo