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Cheap flights from Chicago to Santiago from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:35 am - 12:32 amORD-SCL
13h 57m1 stop
Copa Airlines Logo
4:20 am - 1:24 amSCL-ORD
22h 04m1 stop
$722Copa Airlines
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Fri, Apr 3 - Sat, Apr 11
LATAM Airlines Logo
1:55 pm - 6:55 amORD-SCL
14h 00m1 stop
LATAM Airlines Logo
11:30 pm - 5:45 pmSCL-ORD
21h 15m1 stop
$724LATAM Airlines
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Thu, Jan 15 - Mon, Jan 19
Multiple Airlines Logo
1:00 am - 2:40 pmORD-SCL
34h 40m3 stops
Multiple Airlines Logo
3:45 pm - 11:06 pmSCL-ORD
33h 21m3 stops
$725Multiple Airlines
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Wed, Mar 4 - Sun, Mar 15
Multiple Airlines Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Multiple Airlines Logo
12:40 am - 6:15 pmSCL-ORD
20h 35m2 stops
$726Multiple Airlines
Find Deal
Sat, Feb 28 - Fri, Mar 6
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$728Avianca
Find Deal
Sun, Jan 4 - Mon, Jan 19
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
7:25 am - 8:20 pmSCL-ORD
15h 55m1 stop
$730Avianca
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Fri, Feb 27 - Sat, Mar 7
Multiple Airlines Logo
5:15 am - 2:40 pmORD-SCL
30h 25m2 stops
Multiple Airlines Logo
7:35 am - 8:09 amSCL-ORD
27h 34m3 stops
$731Multiple Airlines
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Wed, Jan 14 - Wed, Jan 21
LATAM Airlines Logo
1:23 pm - 6:55 amORD-SCL
14h 32m1 stop
LATAM Airlines Logo
11:10 pm - 12:06 pmSCL-ORD
15h 56m1 stop
$732LATAM Airlines
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Fri, Dec 5 - Fri, Dec 12
Delta Logo
10:53 am - 7:00 amMDW-SCL
17h 07m1 stop
Delta Logo
11:15 pm - 12:01 pmSCL-MDW
14h 46m1 stop
$739Delta
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Wed, Mar 4 - Sun, Mar 15
Delta Logo
9:34 am - 7:00 amMDW-SCL
18h 26m2 stops
Delta Logo
11:15 pm - 12:35 pmSCL-MDW
15h 20m2 stops
$744Delta
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Thu, Mar 5 - Sun, Mar 15

Copa Airlines flights from Chicago to Santiago

Our best Copa Airlines deals on Chicago to Santiago flight tickets
Copa Airlines
Apr 3
ORD8:35 amChicago O'Hare Intl
13h 57m
1 stop
SCL12:32 amSantiago Arturo Merino Benitez
Apr 11
SCL4:20 amSantiago Arturo Merino Benitez
22h 04m
1 stop
ORD1:24 amChicago O'Hare Intl
$722
Find similar
Copa Airlines
Jan 24
ORD7:35 amChicago O'Hare Intl
13h 57m
1 stop
SCL12:32 amSantiago Arturo Merino Benitez
Feb 4
SCL1:46 amSantiago Arturo Merino Benitez
13h 45m
1 stop
ORD12:31 pmChicago O'Hare Intl
$742
Find similar
Copa Airlines
Nov 24
ORD6:56 amChicago O'Hare Intl
13h 45m
1 stop
SCL11:41 pmSantiago Arturo Merino Benitez
Dec 3
SCL1:29 amSantiago Arturo Merino Benitez
14h 23m
1 stop
ORD12:52 pmChicago O'Hare Intl
$752
Find similar

United Airlines flights from Chicago to Santiago

Our best United Airlines deals on Chicago to Santiago flight tickets
United Airlines
Nov 19
ORD12:45 pmChicago O'Hare Intl
17h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 1
SCL10:45 pmSantiago Arturo Merino Benitez
13h 26m
1 stop
ORD9:11 amChicago O'Hare Intl
$764
Find similar
United Airlines
Nov 21
ORD9:08 pmChicago O'Hare Intl
32h 42m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 2
SCL10:45 pmSantiago Arturo Merino Benitez
13h 27m
1 stop
ORD9:12 amChicago O'Hare Intl
$774
Find similar
United Airlines
Dec 23
ORD9:23 pmChicago O'Hare Intl
32h 27m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 29
SCL10:45 pmSantiago Arturo Merino Benitez
28h 29m
1 stop
ORD12:14 amChicago O'Hare Intl
$783
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momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 4/3

8:35 am-12:32 am

1 stop13h 57m

Santiago Arturo Merino Benitez

Sat 4/11

4:20 am-1:24 am

1 stop22h 04m

$722

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 1/15

1:55 pm-6:55 am

1 stop14h 00m

Santiago Arturo Merino Benitez

Mon 1/19

11:30 pm-5:45 pm

1 stop21h 15m

$724

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 3/4

1:00 am-2:40 pm

3 stops34h 40m

Santiago Arturo Merino Benitez

Sun 3/15

3:45 pm-11:06 pm

3 stops33h 21m

$725

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 2/28

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Fri 3/6

12:40 am-6:15 pm

2 stops20h 35m

$726

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 1/4

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Mon 1/19

1:35 am-8:20 pm

1 stop21h 45m

$728

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 2/27

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Sat 3/7

7:25 am-8:20 pm

1 stop15h 55m

$730

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 1/14

5:15 am-2:40 pm

2 stops30h 25m

Santiago Arturo Merino Benitez

Wed 1/21

7:35 am-8:09 am

3 stops27h 34m

$731

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 12/5

1:23 pm-6:55 am

1 stop14h 32m

Santiago Arturo Merino Benitez

Fri 12/12

11:10 pm-12:06 pm

1 stop15h 56m

$732

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Wed 3/4

10:53 am-7:00 am

1 stop17h 07m

Santiago Arturo Merino Benitez

Sun 3/15

11:15 pm-12:01 pm

1 stop14h 46m

$739

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 3/5

9:34 am-7:00 am

2 stops18h 26m

Santiago Arturo Merino Benitez

Sun 3/15

11:15 pm-12:35 pm

2 stops15h 20m

$744

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $665. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $704.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $852 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 31% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of November 2025, prices for Chicago to Santiago flights are approximately 26% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Direct flights

None
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
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  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 13h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,444 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,475 reviews
Search Avianca flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,016 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $667Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,875 reviews
Search LATAM Airlines flights
DeltaPriceFrom $699Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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