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Cheap flights from Chicago to Santiago from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 10/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago to Santiago (CHI-SCL)

Cheap round-trip flights

Logo
9:06 pm - 3:35 amORD-SCL
28h 29m2 stops
Logo
4:25 pm - 9:22 amSCL-ORD
18h 57m2 stops
$532
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Mon, Oct 20 - Mon, Oct 27
Logo
3:36 pm - 3:35 amORD-SCL
33h 59m3 stops
Logo
4:25 pm - 9:22 amSCL-ORD
18h 57m2 stops
$546
Find Deal
Mon, Oct 20 - Mon, Oct 27
Avianca Logo
2:35 pm - 2:25 pmORD-SCL
21h 50m1 stop
Avianca Logo
3:30 pm - 1:15 pmSCL-ORD
23h 45m1 stop
$690Avianca
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Fri, Oct 17 - Tue, Oct 21
Air Canada Logo
7:15 am - 7:00 amORD-SCL
20h 45m1 stop
Air Canada Logo
8:55 pm - 1:01 pmSCL-ORD
19h 06m1 stop
$691Air Canada
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Tue, Jan 27 - Tue, Feb 10
Avianca Logo
2:35 pm - 5:15 amORD-SCL
12h 40m1 stop
Avianca Logo
12:55 am - 1:15 pmSCL-ORD
14h 20m1 stop
$707Avianca
Find Deal
Tue, Sep 9 - Sun, Sep 21
Air Canada Logo
7:15 am - 7:00 amORD-SCL
20h 45m1 stop
Air Canada Logo
8:35 am - 2:55 pmSCL-ORD
33h 20m1 stop
$729Air Canada
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Sat, Feb 14 - Sun, Feb 22
LATAM Airlines Logo
1:05 pm - 6:50 amORD-SCL
15h 45m2 stops
LATAM Airlines Logo
11:30 pm - 5:45 pmSCL-ORD
20h 15m2 stops
$731LATAM Airlines
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Wed, Sep 24 - Tue, Sep 30
LATAM Airlines Logo
10:35 am - 5:35 amMDW-SCL
16h 00m2 stops
LATAM Airlines Logo
11:15 pm - 12:01 pmSCL-MDW
15h 46m1 stop
$757LATAM Airlines
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Tue, Jan 27 - Tue, Feb 10
Delta Logo
10:47 am - 7:40 amMDW-SCL
17h 53m1 stop
Delta Logo
9:30 pm - 9:51 amSCL-MDW
15h 21m1 stop
$784Delta
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Thu, Nov 27 - Mon, Dec 8
Delta Logo
9:30 am - 7:00 amMDW-SCL
18h 30m2 stops
Delta Logo
11:15 pm - 12:01 pmSCL-MDW
15h 46m1 stop
$788Delta
Find Deal
Tue, Jan 27 - Tue, Feb 10

Avianca flights from Chicago to Santiago

Our best Avianca deals on Chicago to Santiago flight tickets
Avianca
Oct 17
ORD2:35 pmChicago O'Hare Intl
21h 50m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Oct 21
SCL3:30 pmSantiago Arturo Merino Benitez
23h 45m
1 stop
ORD1:15 pmChicago O'Hare Intl
$690
Find similar
Avianca
Sep 9
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Sep 21
SCL12:55 amSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$707
Find similar
Avianca
Oct 26
ORD11:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Nov 10
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD8:20 pmChicago O'Hare Intl
$717
Find similar

Air Canada flights from Chicago to Santiago

Our best Air Canada deals on Chicago to Santiago flight tickets
Air Canada
Jan 27
ORD7:15 amChicago O'Hare Intl
20h 45m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 10
SCL8:55 pmSantiago Arturo Merino Benitez
19h 06m
1 stop
ORD1:01 pmChicago O'Hare Intl
$691
Find similar
Air Canada
Feb 14
ORD7:15 amChicago O'Hare Intl
20h 45m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 22
SCL8:35 amSantiago Arturo Merino Benitez
33h 20m
1 stop
ORD2:55 pmChicago O'Hare Intl
$729
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 10/20

9:06 pm-3:35 am

2 stops28h 29m

Santiago Arturo Merino Benitez

Mon 10/27

4:25 pm-9:22 am

2 stops18h 57m

$532

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 10/20

3:36 pm-3:35 am

3 stops33h 59m

Santiago Arturo Merino Benitez

Mon 10/27

4:25 pm-9:22 am

2 stops18h 57m

$546

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 10/17

2:35 pm-2:25 pm

1 stop21h 50m

Santiago Arturo Merino Benitez

Tue 10/21

3:30 pm-1:15 pm

1 stop23h 45m

$690

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 1/27

7:15 am-7:00 am

1 stop20h 45m

Santiago Arturo Merino Benitez

Tue 2/10

8:55 pm-1:01 pm

1 stop19h 06m

$691

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 9/9

2:35 pm-5:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Sun 9/21

12:55 am-1:15 pm

1 stop14h 20m

$707

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 2/14

7:15 am-7:00 am

1 stop20h 45m

Santiago Arturo Merino Benitez

Sun 2/22

8:35 am-2:55 pm

1 stop33h 20m

$729

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 9/24

1:05 pm-6:50 am

2 stops15h 45m

Santiago Arturo Merino Benitez

Tue 9/30

11:30 pm-5:45 pm

2 stops20h 15m

$731

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

10:35 am-5:35 am

2 stops16h 00m

Santiago Arturo Merino Benitez

Tue 2/10

11:15 pm-12:01 pm

1 stop15h 46m

$757

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 11/27

10:47 am-7:40 am

1 stop17h 53m

Santiago Arturo Merino Benitez

Mon 12/8

9:30 pm-9:51 am

1 stop15h 21m

$784

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

9:30 am-7:00 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Tue 2/10

11:15 pm-12:01 pm

1 stop15h 46m

$788

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $684. If you don’t want to visit Santiago in April, then you should wait until September to fly from Chicago, when ticket prices are also cheap, with an average price of $799.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $868 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $775 on momondo.

How have Chicago to Santiago flight prices changed over time?

As of August 2025, prices for Chicago to Santiago flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Direct flights

None
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
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  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 11h 56m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $511Free CancellationRating
7.5
1,517 reviews
Search Copa Airlines flights
AviancaPriceFrom $539Free CancellationRating
6.7
2,420 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $694Free CancellationRating
7.5
1,842 reviews
Search LATAM Airlines flights
DeltaPriceFrom $698Free CancellationRating
7.9
7,977 reviews
Search Delta flights
Air CanadaPriceFrom $707Free CancellationRating
7.1
10,000 reviews
Search Air Canada flights
American AirlinesPriceFrom $750Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $782Free CancellationRating
7.4
8,944 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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