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Cheap flights from Chicago to Santiago from $303

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:29 pm - 7:40 am
MDW
-
SCL
15h 11m2 stops
Delta Logo
11:10 pm - 12:46 pm
SCL
-
MDW
16h 36m2 stops
$655Delta
Tue, Jan 27 - Wed, Feb 11
Delta Logo
8:55 am - 5:55 am
ORD
-
SCL
19h 00m2 stops
Delta Logo
10:10 pm - 4:43 pm
SCL
-
ORD
20h 33m2 stops
$655Delta
Tue, Mar 10 - Tue, Mar 17
Multiple Airlines Logo
10:20 pm - 3:20 pm
ORD
-
SCL
14h 00m1 stop
Multiple Airlines Logo
9:05 pm - 6:16 pm
SCL
-
ORD
24h 11m2 stops
$661Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
LATAM Airlines Logo
10:48 am - 7:40 am
MDW
-
SCL
17h 52m1 stop
LATAM Airlines Logo
11:10 pm - 5:45 pm
SCL
-
MDW
21h 35m1 stop
$670LATAM Airlines
Tue, Jan 27 - Wed, Feb 11
LATAM Airlines Logo
5:25 pm - 7:00 am
MDW
-
SCL
12h 35m1 stop
LATAM Airlines Logo
8:40 pm - 9:51 am
SCL
-
MDW
14h 11m1 stop
$672LATAM Airlines
Fri, May 15 - Sat, May 23
Multiple Airlines Logo
6:57 pm - 10:15 pm
ORD
-
SCL
24h 18m2 stops
Multiple Airlines Logo
9:05 pm - 6:16 pm
SCL
-
ORD
24h 11m2 stops
$672Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
LATAM Airlines Logo
10:49 am - 7:40 am
MDW
-
SCL
18h 51m1 stop
LATAM Airlines Logo
8:40 pm - 10:29 pm
SCL
-
MDW
27h 49m1 stop
$678LATAM Airlines
Thu, Mar 19 - Sun, Mar 29
LATAM Airlines Logo
9:43 am - 7:40 am
ORD
-
SCL
19h 57m1 stop
LATAM Airlines Logo
8:40 pm - 6:46 pm
SCL
-
ORD
24h 06m1 stop
$678LATAM Airlines
Thu, Mar 19 - Sun, Mar 29
Avianca Logo
11:20 pm - 3:20 pm
ORD
-
SCL
14h 00m1 stop
Avianca Logo
7:25 am - 9:20 pm
SCL
-
ORD
15h 55m1 stop
$679Avianca
Wed, Mar 11 - Sat, Mar 21
LATAM Airlines Logo
10:53 am - 7:40 am
MDW
-
SCL
17h 47m1 stop
LATAM Airlines Logo
7:15 am - 12:02 pm
SCL
-
MDW
30h 47m3 stops
$680LATAM Airlines
Tue, Mar 3 - Wed, Mar 25

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Jan 27
MDW10:48 amChicago Midway
17h 52m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Feb 11
SCL11:10 pmSantiago Arturo Merino Benitez
21h 35m
1 stop
MDW5:45 pmChicago Midway
$670
Find similar
LATAM Airlines
May 15
MDW5:25 pmChicago Midway
12h 35m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
May 23
SCL8:40 pmSantiago Arturo Merino Benitez
14h 11m
1 stop
MDW9:51 amChicago Midway
$672
Find similar
LATAM Airlines
Mar 19
MDW12:47 pmChicago Midway
16h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 29
SCL8:40 pmSantiago Arturo Merino Benitez
27h 49m
1 stop
MDW10:29 pmChicago Midway
$678
Find similar

Avianca flights from Chicago to Santiago

Our best Avianca deals on Chicago to Santiago flight tickets
Avianca
Mar 11
ORD11:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Mar 21
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD9:20 pmChicago O'Hare Intl
$679
Find similar
Avianca
Feb 13
ORD10:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Feb 21
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD8:20 pmChicago O'Hare Intl
$701
Find similar
Avianca
Feb 20
ORD10:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Feb 23
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD8:20 pmChicago O'Hare Intl
$716
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 7, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

1:29 pm-7:40 am

2 stops15h 11m

Santiago Arturo Merino Benitez

Wed 2/11

11:10 pm-12:46 pm

2 stops16h 36m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 3/10

8:55 am-5:55 am

2 stops19h 00m

Santiago Arturo Merino Benitez

Tue 3/17

10:10 pm-4:43 pm

2 stops20h 33m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 1/18

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Sun 1/25

9:05 pm-6:16 pm

2 stops24h 11m

$661

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

Wed 2/11

11:10 pm-5:45 pm

1 stop21h 35m

$670

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Fri 5/15

5:25 pm-7:00 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Sat 5/23

8:40 pm-9:51 am

1 stop14h 11m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 1/18

6:57 pm-10:15 pm

2 stops24h 18m

Santiago Arturo Merino Benitez

Sun 1/25

9:05 pm-6:16 pm

2 stops24h 11m

$672

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 3/19

10:49 am-7:40 am

1 stop18h 51m

Santiago Arturo Merino Benitez

Sun 3/29

8:40 pm-10:29 pm

1 stop27h 49m

$678

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 3/19

9:43 am-7:40 am

1 stop19h 57m

Santiago Arturo Merino Benitez

Sun 3/29

8:40 pm-6:46 pm

1 stop24h 06m

$678

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 3/11

11:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Sat 3/21

7:25 am-9:20 pm

1 stop15h 55m

$679

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 3/3

10:53 am-7:40 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Wed 3/25

7:15 am-12:02 pm

3 stops30h 47m

$680

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $659. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $775.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $870 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 26% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of December 2025, prices for Chicago to Santiago flights are approximately 52% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Fastest flight time

12h 02m

Direct flights

None
The fastest flight from Chicago to Santiago takes 12h 02m
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
Search flight deals

  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,512 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,477 reviews
Search Avianca flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,076 reviews
Search United Airlines flights
DeltaPriceFrom $626Free CancellationRating
7.9
8,013 reviews
Search Delta flights
American AirlinesPriceFrom $639Free CancellationRating
7.2
11,044 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.6
1,555 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

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