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Cheap flights from Chicago to Santiago from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:20 pm - 3:20 pm
ORD
-
SCL
14h 00m1 stop
Multiple Airlines Logo
4:20 am - 12:53 am
SCL
-
ORD
23h 33m3 stops
$551Multiple Airlines
mié., mar. 4 - jue., mar. 5
Multiple Airlines Logo
10:20 pm - 3:20 pm
ORD
-
SCL
14h 00m1 stop
Multiple Airlines Logo
4:20 am - 9:53 am
SCL
-
ORD
32h 33m2 stops
$558Multiple Airlines
mié., mar. 4 - jue., mar. 5
Multiple Airlines Logo
7:35 am - 8:15 am
ORD
-
SCL
21h 40m2 stops
Multiple Airlines Logo
1:35 am - 9:53 am
SCL
-
ORD
34h 18m3 stops
$569Multiple Airlines
vie., mar. 6 - jue., mar. 12
United Airlines Logo
5:45 am - 8:50 am
ORD
-
SCL
24h 05m1 stop
United Airlines Logo
9:45 pm - 5:05 pm
SCL
-
ORD
21h 20m1 stop
$597United Airlines
mar., mar. 3 - mié., mar. 11
American Airlines Logo
4:49 pm - 9:00 am
ORD
-
SCL
13h 11m1 stop
American Airlines Logo
10:35 pm - 11:06 am
SCL
-
ORD
15h 31m1 stop
$600American Airlines
jue., ene. 29 - dom., feb. 8
American Airlines Logo
1:35 pm - 9:00 am
ORD
-
SCL
16h 25m2 stops
American Airlines Logo
10:35 pm - 11:35 am
SCL
-
ORD
16h 00m2 stops
$602American Airlines
mar., ene. 27 - mar., feb. 10
Delta Logo
6:00 am - 7:40 am
MDW
-
SCL
22h 40m1 stop
Delta Logo
10:10 pm - 12:29 pm
SCL
-
MDW
16h 19m2 stops
$644Delta
lun., mar. 2 - dom., mar. 15
LATAM Airlines Logo
10:48 am - 7:40 am
MDW
-
SCL
17h 52m1 stop
LATAM Airlines Logo
11:10 pm - 9:54 am
SCL
-
MDW
13h 44m1 stop
$649LATAM Airlines
dom., feb. 8 - mar., feb. 24
Delta Logo
5:40 pm - 7:40 am
MDW
-
SCL
12h 00m1 stop
Delta Logo
6:30 pm - 12:02 pm
SCL
-
MDW
19h 32m2 stops
$651Delta
lun., mar. 9 - mié., mar. 25
LATAM Airlines Logo
10:48 am - 7:40 am
MDW
-
SCL
17h 52m1 stop
LATAM Airlines Logo
11:10 pm - 9:54 am
SCL
-
MDW
13h 44m1 stop
$675LATAM Airlines
jue., feb. 5 - jue., feb. 12

Delta flights from Chicago to Santiago

Our best Delta deals on Chicago to Santiago flight tickets
Delta
Mar 2
MDW6:00 amChicago Midway
22h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 15
SCL10:10 pmSantiago Arturo Merino Benitez
16h 19m
2 stops
MDW12:29 pmChicago Midway
$644
Delta
Mar 9
MDW12:47 pmChicago Midway
16h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 25
SCL10:10 pmSantiago Arturo Merino Benitez
13h 46m
1 stop
MDW9:56 amChicago Midway
$651
Delta
Mar 9
MDW1:10 pmChicago Midway
16h 30m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Mar 19
SCL10:30 pmSantiago Arturo Merino Benitez
20h 25m
2 stops
MDW4:55 pmChicago Midway
$656

Avianca flights from Chicago to Santiago

Our best Avianca deals on Chicago to Santiago flight tickets
Avianca
Mar 16
ORD11:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Mar 21
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD9:20 pmChicago O'Hare Intl
$605
Avianca
Apr 29
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
May 18
SCL11:55 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$629
Avianca
Mar 4
ORD10:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Mar 6
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD8:20 pmChicago O'Hare Intl
$638

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 3/4

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

jue. 3/5

4:20 am-12:53 am

3 stops23h 33m

$551

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 3/4

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

jue. 3/5

4:20 am-9:53 am

2 stops32h 33m

$558

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

vie. 3/6

7:35 am-8:15 am

2 stops21h 40m

Santiago Arturo Merino Benitez

jue. 3/12

1:35 am-9:53 am

3 stops34h 18m

$569

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mar. 3/3

5:45 am-8:50 am

1 stop24h 05m

Santiago Arturo Merino Benitez

mié. 3/11

9:45 pm-5:05 pm

1 stop21h 20m

$597

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

jue. 1/29

4:49 pm-9:00 am

1 stop13h 11m

Santiago Arturo Merino Benitez

dom. 2/8

10:35 pm-11:06 am

1 stop15h 31m

$600

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mar. 1/27

1:35 pm-9:00 am

2 stops16h 25m

Santiago Arturo Merino Benitez

mar. 2/10

10:35 pm-11:35 am

2 stops16h 00m

$602

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

lun. 3/2

6:00 am-7:40 am

1 stop22h 40m

Santiago Arturo Merino Benitez

dom. 3/15

10:10 pm-12:29 pm

2 stops16h 19m

$644

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

dom. 2/8

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

mar. 2/24

11:10 pm-9:54 am

1 stop13h 44m

$649

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

lun. 3/9

5:40 pm-7:40 am

1 stop12h 00m

Santiago Arturo Merino Benitez

mié. 3/25

6:30 pm-12:02 pm

2 stops19h 32m

$651

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

jue. 2/5

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

jue. 2/12

11:10 pm-9:54 am

1 stop13h 44m

$675

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $659. If you don’t want to visit Santiago in September, then you should wait until January to fly from Chicago, when ticket prices are also cheap, with an average price of $717.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $850 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 45% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of January 2026, prices for Chicago to Santiago flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Fastest flight time

12h 40m

Direct flights

None
The fastest flight from Chicago to Santiago takes 12h 40m
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
Search flight deals

  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,603 reviews
Search Air Canada flights
AviancaPriceFrom $558Free CancellationRating
6.6
2,492 reviews
Search Avianca flights
Copa AirlinesPriceFrom $615Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,143 reviews
Search United Airlines flights
DeltaPriceFrom $626Free CancellationRating
7.9
8,032 reviews
Search Delta flights
American AirlinesPriceFrom $630Free CancellationRating
7.2
11,097 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $637Free CancellationRating
7.5
1,901 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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