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Cheap flights from Chicago to Santiago from $264

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 2/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:48 am - 6:55 amORD-SCL
16h 07m1 stop
Multiple Airlines Logo
9:10 pm - 6:36 pmSCL-ORD
24h 26m2 stops
$686Multiple Airlines
Find Deal
lun., nov. 24 - mer., déc. 3
LATAM Airlines Logo
11:19 am - 7:00 amORD-SCL
16h 41m2 stops
LATAM Airlines Logo
11:30 pm - 12:43 pmSCL-ORD
16h 13m1 stop
$687LATAM Airlines
Find Deal
jeu., nov. 27 - sam., déc. 6
Air Canada Logo
7:15 am - 7:00 amORD-SCL
20h 45m1 stop
Air Canada Logo
8:55 pm - 9:13 amSCL-ORD
15h 18m1 stop
$691Air Canada
Find Deal
sam., janv. 24 - jeu., févr. 5
United Airlines Logo
2:21 pm - 8:50 amORD-SCL
15h 29m1 stop
United Airlines Logo
10:45 pm - 9:11 amSCL-ORD
13h 26m1 stop
$695United Airlines
Find Deal
mer., nov. 19 - lun., déc. 1
Air Canada Logo
5:52 pm - 7:00 amORD-SCL
34h 08m1 stop
Air Canada Logo
8:55 pm - 10:05 pmSCL-ORD
28h 10m1 stop
$696Air Canada
Find Deal
lun., janv. 19 - jeu., janv. 29
Delta Logo
6:27 pm - 7:40 amORD-SCL
34h 13m1 stop
Delta Logo
11:10 pm - 10:14 amSCL-ORD
14h 04m1 stop
$703Delta
Find Deal
sam., nov. 22 - sam., déc. 13
United Airlines Logo
9:08 pm - 8:50 amORD-SCL
32h 42m1 stop
United Airlines Logo
10:45 pm - 11:11 amSCL-ORD
15h 26m1 stop
$704United Airlines
Find Deal
ven., nov. 21 - ven., déc. 12
Delta Logo
11:21 am - 6:10 amMDW-SCL
15h 49m1 stop
Delta Logo
8:15 am - 10:26 pmSCL-MDW
17h 11m2 stops
$714Delta
Find Deal
lun., janv. 12 - lun., janv. 26
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$723Avianca
Find Deal
mar., janv. 27 - lun., févr. 9
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
7:25 am - 8:20 pmSCL-ORD
15h 55m1 stop
$737Avianca
Find Deal
lun., janv. 19 - lun., janv. 26

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Nov 27
ORD11:19 amChicago O'Hare Intl
16h 41m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Dec 6
SCL11:30 pmSantiago Arturo Merino Benitez
16h 13m
1 stop
ORD12:43 pmChicago O'Hare Intl
$687
Find similar
LATAM Airlines
Nov 18
MDW12:47 pmChicago Midway
15h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 25
SCL11:10 pmSantiago Arturo Merino Benitez
15h 42m
1 stop
MDW11:52 amChicago Midway
$690
Find similar
LATAM Airlines
Nov 14
MDW12:47 pmChicago Midway
15h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 3
SCL11:10 pmSantiago Arturo Merino Benitez
15h 45m
1 stop
MDW11:55 amChicago Midway
$695
Find similar

Delta flights from Chicago to Santiago

Our best Delta deals on Chicago to Santiago flight tickets
Delta
Nov 22
ORD6:27 pmChicago O'Hare Intl
34h 13m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 13
SCL11:10 pmSantiago Arturo Merino Benitez
14h 04m
1 stop
ORD10:14 amChicago O'Hare Intl
$703
Find similar
Delta
Jan 12
MDW11:21 amChicago Midway
15h 49m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
Jan 26
SCL8:15 amSantiago Arturo Merino Benitez
17h 11m
2 stops
MDW10:26 pmChicago Midway
$714
Find similar
Delta
Jan 27
MDW9:34 amChicago Midway
19h 06m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Feb 10
SCL6:30 pmSantiago Arturo Merino Benitez
20h 31m
2 stops
MDW12:01 pmChicago Midway
$719
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octobre 30, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

lun. 11/24

11:48 am-6:55 am

1 stop16h 07m

Santiago Arturo Merino Benitez

mer. 12/3

9:10 pm-6:36 pm

2 stops24h 26m

$686

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

jeu. 11/27

11:19 am-7:00 am

2 stops16h 41m

Santiago Arturo Merino Benitez

sam. 12/6

11:30 pm-12:43 pm

1 stop16h 13m

$687

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

sam. 1/24

7:15 am-7:00 am

1 stop20h 45m

Santiago Arturo Merino Benitez

jeu. 2/5

8:55 pm-9:13 am

1 stop15h 18m

$691

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mer. 11/19

2:21 pm-8:50 am

1 stop15h 29m

Santiago Arturo Merino Benitez

lun. 12/1

10:45 pm-9:11 am

1 stop13h 26m

$695

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

lun. 1/19

5:52 pm-7:00 am

1 stop34h 08m

Santiago Arturo Merino Benitez

jeu. 1/29

8:55 pm-10:05 pm

1 stop28h 10m

$696

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

sam. 11/22

6:27 pm-7:40 am

1 stop34h 13m

Santiago Arturo Merino Benitez

sam. 12/13

11:10 pm-10:14 am

1 stop14h 04m

$703

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

ven. 11/21

9:08 pm-8:50 am

1 stop32h 42m

Santiago Arturo Merino Benitez

ven. 12/12

10:45 pm-11:11 am

1 stop15h 26m

$704

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

lun. 1/12

11:21 am-6:10 am

1 stop15h 49m

Santiago Arturo Merino Benitez

lun. 1/26

8:15 am-10:26 pm

2 stops17h 11m

$714

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mar. 1/27

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

lun. 2/9

1:35 am-8:20 pm

1 stop21h 45m

$723

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

lun. 1/19

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

lun. 1/26

7:25 am-8:20 pm

1 stop15h 55m

$737

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $665. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $704.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $866 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 31% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of October 2025, prices for Chicago to Santiago flights are approximately 40% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Direct flights

None
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
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  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $564Free CancellationRating
6.6
2,467 reviews
Search Avianca flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,873 reviews
Search LATAM Airlines flights
DeltaPriceFrom $699Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $703Free CancellationRating
7.2
11,035 reviews
Search American Airlines flights
Air CanadaPriceFrom $707Free CancellationRating
7.1
10,381 reviews
Search Air Canada flights
United AirlinesPriceFrom $748Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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