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Cheap flights from Chicago to Santiago from $258

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:20 am - 6:40 am
ORD
-
SCL
20h 20m2 stops
Multiple Airlines Logo
9:05 pm - 12:40 am
SCL
-
ORD
30h 35m3 stops
$617Multiple Airlines
Tue, Feb 10 - Tue, Feb 17
Delta Logo
6:30 pm - 7:40 am
ORD
-
SCL
34h 10m1 stop
Delta Logo
10:10 pm - 4:49 pm
SCL
-
ORD
20h 39m1 stop
$618Delta
Sat, Feb 28 - Tue, Mar 10
United Airlines Logo
4:50 pm - 8:50 am
ORD
-
SCL
13h 00m1 stop
United Airlines Logo
10:45 pm - 9:26 pm
SCL
-
ORD
25h 41m1 stop
$619United Airlines
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
6:34 pm - 2:35 am
ORD
-
SCL
31h 01m2 stops
Multiple Airlines Logo
11:55 pm - 1:15 pm
SCL
-
ORD
14h 20m1 stop
$620Multiple Airlines
Mon, Apr 20 - Sun, May 3
Avianca Logo
2:35 pm - 4:15 am
ORD
-
SCL
12h 40m1 stop
Avianca Logo
11:55 pm - 1:15 pm
SCL
-
ORD
14h 20m1 stop
$621Avianca
Mon, Apr 20 - Sun, May 3
Delta Logo
6:30 pm - 7:40 am
ORD
-
SCL
34h 10m1 stop
Delta Logo
11:25 pm - 4:43 pm
SCL
-
ORD
19h 18m2 stops
$622Delta
Sat, Feb 28 - Sun, Mar 15
LATAM Airlines Logo
7:00 am - 5:55 am
ORD
-
SCL
20h 55m1 stop
LATAM Airlines Logo
6:30 pm - 12:57 pm
SCL
-
ORD
20h 27m2 stops
$623LATAM Airlines
Sun, Mar 15 - Thu, Mar 26
Multiple Airlines Logo
6:34 pm - 2:35 am
ORD
-
SCL
31h 01m2 stops
Multiple Airlines Logo
11:55 pm - 1:15 pm
SCL
-
ORD
14h 20m1 stop
$625Multiple Airlines
Mon, Apr 20 - Sat, Apr 25
Avianca Logo
2:35 pm - 4:15 am
ORD
-
SCL
12h 40m1 stop
Avianca Logo
11:55 pm - 1:15 pm
SCL
-
ORD
14h 20m1 stop
$626Avianca
Tue, Apr 14 - Sat, Apr 25
LATAM Airlines Logo
12:48 pm - 7:40 am
MDW
-
SCL
15h 52m1 stop
LATAM Airlines Logo
11:25 pm - 11:59 am
SCL
-
MDW
15h 34m2 stops
$628LATAM Airlines
Tue, Jan 27 - Tue, Feb 10

Avianca flights from Chicago to Santiago

Our best Avianca deals on Chicago to Santiago flight tickets
Avianca
Apr 20
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
May 3
SCL11:55 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$621
Find similar
Avianca
Apr 14
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
Apr 24
SCL11:55 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$626
Find similar
Avianca
Apr 26
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
Apr 30
SCL11:55 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$630
Find similar

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Mar 15
ORD7:00 amChicago O'Hare Intl
20h 55m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 26
SCL6:30 pmSantiago Arturo Merino Benitez
20h 27m
2 stops
ORD12:57 pmChicago O'Hare Intl
$623
Find similar
LATAM Airlines
Jan 27
MDW12:48 pmChicago Midway
15h 52m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Feb 10
SCL11:25 pmSantiago Arturo Merino Benitez
15h 34m
2 stops
MDW11:59 amChicago Midway
$628
Find similar
LATAM Airlines
Mar 4
ORD2:46 pmChicago O'Hare Intl
13h 54m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 12
SCL11:25 pmSantiago Arturo Merino Benitez
19h 24m
2 stops
ORD4:49 pmChicago O'Hare Intl
$631
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 2/10

7:20 am-6:40 am

2 stops20h 20m

Santiago Arturo Merino Benitez

Tue 2/17

9:05 pm-12:40 am

3 stops30h 35m

$617

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 2/28

6:30 pm-7:40 am

1 stop34h 10m

Santiago Arturo Merino Benitez

Tue 3/10

10:10 pm-4:49 pm

1 stop20h 39m

$618

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 1/25

4:50 pm-8:50 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Sun 2/1

10:45 pm-9:26 pm

1 stop25h 41m

$619

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/20

6:34 pm-2:35 am

2 stops31h 01m

Santiago Arturo Merino Benitez

Sun 5/3

11:55 pm-1:15 pm

1 stop14h 20m

$620

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/20

2:35 pm-4:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Sun 5/3

11:55 pm-1:15 pm

1 stop14h 20m

$621

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 2/28

6:30 pm-7:40 am

1 stop34h 10m

Santiago Arturo Merino Benitez

Sun 3/15

11:25 pm-4:43 pm

2 stops19h 18m

$622

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 3/15

7:00 am-5:55 am

1 stop20h 55m

Santiago Arturo Merino Benitez

Thu 3/26

6:30 pm-12:57 pm

2 stops20h 27m

$623

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/20

6:34 pm-2:35 am

2 stops31h 01m

Santiago Arturo Merino Benitez

Sat 4/25

11:55 pm-1:15 pm

1 stop14h 20m

$625

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 4/14

2:35 pm-4:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Sat 4/25

11:55 pm-1:15 pm

1 stop14h 20m

$626

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

12:48 pm-7:40 am

1 stop15h 52m

Santiago Arturo Merino Benitez

Tue 2/10

11:25 pm-11:59 am

2 stops15h 34m

$628

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $659. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $775.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $871 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 26% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of December 2025, prices for Chicago to Santiago flights are approximately 52% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Fastest flight time

12h 15m

Direct flights

None
The fastest flight from Chicago to Santiago takes 12h 15m
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
Search flight deals

  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,562 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,489 reviews
Search Avianca flights
Copa AirlinesPriceFrom $615Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
DeltaPriceFrom $626Free CancellationRating
7.9
8,021 reviews
Search Delta flights
American AirlinesPriceFrom $630Free CancellationRating
7.2
11,069 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,896 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $713Free CancellationRating
7.4
9,116 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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