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Cheap flights from Chicago to Santiago from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
10:40 am - 5:35 amORD-SCL
16h 55m2 stops
LATAM Airlines Logo
10:30 pm - 12:44 pmSCL-ORD
16h 14m1 stop
$733LATAM Airlines
Find Deal
Sun, Mar 15 - Fri, Mar 27
Multiple Airlines Logo
5:00 am - 10:39 amORD-SCL
26h 39m2 stops
Multiple Airlines Logo
1:35 am - 8:09 amSCL-ORD
33h 34m2 stops
$737Multiple Airlines
Find Deal
Fri, Jan 2 - Sat, Jan 24
LATAM Airlines Logo
10:40 am - 5:55 amORD-SCL
17h 15m1 stop
LATAM Airlines Logo
11:55 pm - 5:37 pmSCL-ORD
19h 42m1 stop
$739LATAM Airlines
Find Deal
Fri, Mar 13 - Tue, Mar 31
LATAM Airlines Logo
10:40 am - 5:35 amORD-SCL
16h 55m2 stops
LATAM Airlines Logo
11:25 pm - 4:39 pmSCL-ORD
19h 14m2 stops
$741LATAM Airlines
Find Deal
Sun, Mar 15 - Thu, Mar 26
LATAM Airlines Logo
10:48 am - 7:40 amMDW-SCL
17h 52m1 stop
LATAM Airlines Logo
11:15 pm - 10:44 pmSCL-MDW
26h 29m1 stop
$742LATAM Airlines
Find Deal
Sun, Feb 8 - Sun, Feb 15
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$743Avianca
Find Deal
Sun, Dec 14 - Tue, Dec 23
Delta Logo
9:30 am - 7:00 amMDW-SCL
19h 30m2 stops
Delta Logo
11:15 pm - 12:35 pmSCL-MDW
15h 20m2 stops
$744Delta
Find Deal
Mon, Mar 9 - Sun, Mar 22
Delta Logo
9:48 am - 5:35 amORD-SCL
16h 47m2 stops
Delta Logo
11:15 pm - 8:38 pmSCL-ORD
23h 23m2 stops
$744Delta
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Fri, Mar 6 - Mon, Mar 16
Copa Airlines Logo
8:35 am - 3:14 amORD-SCL
17h 39m1 stop
Copa Airlines Logo
12:16 am - 1:46 pmSCL-ORD
14h 30m1 stop
$745Copa Airlines
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Sat, May 9 - Fri, May 15
United Airlines Logo
4:00 pm - 8:50 amORD-SCL
13h 50m1 stop
United Airlines Logo
10:45 pm - 9:26 pmSCL-ORD
25h 41m1 stop
$748United Airlines
Find Deal
Sun, Jan 4 - Sun, Jan 25

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Mar 15
ORD10:40 amChicago O'Hare Intl
16h 55m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 27
SCL10:30 pmSantiago Arturo Merino Benitez
16h 14m
1 stop
ORD12:44 pmChicago O'Hare Intl
$733
Find similar
LATAM Airlines
Mar 13
ORD10:40 amChicago O'Hare Intl
17h 15m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 31
SCL11:55 pmSantiago Arturo Merino Benitez
19h 42m
1 stop
ORD5:37 pmChicago O'Hare Intl
$739
Find similar
LATAM Airlines
Mar 15
ORD10:40 amChicago O'Hare Intl
16h 55m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 26
SCL11:25 pmSantiago Arturo Merino Benitez
19h 14m
2 stops
ORD4:39 pmChicago O'Hare Intl
$741
Find similar

United Airlines flights from Chicago to Santiago

Our best United Airlines deals on Chicago to Santiago flight tickets
United Airlines
Jan 4
ORD4:00 pmChicago O'Hare Intl
13h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 25
SCL10:45 pmSantiago Arturo Merino Benitez
25h 41m
1 stop
ORD9:26 pmChicago O'Hare Intl
$748
Find similar
United Airlines
Dec 6
ORD4:45 pmChicago O'Hare Intl
13h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 9
SCL10:45 pmSantiago Arturo Merino Benitez
21h 18m
1 stop
ORD5:03 pmChicago O'Hare Intl
$764
Find similar
United Airlines
Mar 7
ORD2:10 pmChicago O'Hare Intl
15h 40m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 18
SCL9:45 pmSantiago Arturo Merino Benitez
15h 25m
1 stop
ORD11:10 amChicago O'Hare Intl
$789
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 3/15

10:40 am-5:35 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Fri 3/27

10:30 pm-12:44 pm

1 stop16h 14m

$733

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 1/2

5:00 am-10:39 am

2 stops26h 39m

Santiago Arturo Merino Benitez

Sat 1/24

1:35 am-8:09 am

2 stops33h 34m

$737

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 3/13

10:40 am-5:55 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Tue 3/31

11:55 pm-5:37 pm

1 stop19h 42m

$739

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 3/15

10:40 am-5:35 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Thu 3/26

11:25 pm-4:39 pm

2 stops19h 14m

$741

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 2/8

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

Sun 2/15

11:15 pm-10:44 pm

1 stop26h 29m

$742

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 12/14

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Tue 12/23

1:35 am-8:20 pm

1 stop21h 45m

$743

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 3/9

9:30 am-7:00 am

2 stops19h 30m

Santiago Arturo Merino Benitez

Sun 3/22

11:15 pm-12:35 pm

2 stops15h 20m

$744

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 3/6

9:48 am-5:35 am

2 stops16h 47m

Santiago Arturo Merino Benitez

Mon 3/16

11:15 pm-8:38 pm

2 stops23h 23m

$744

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 5/9

8:35 am-3:14 am

1 stop17h 39m

Santiago Arturo Merino Benitez

Fri 5/15

12:16 am-1:46 pm

1 stop14h 30m

$745

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 1/4

4:00 pm-8:50 am

1 stop13h 50m

Santiago Arturo Merino Benitez

Sun 1/25

10:45 pm-9:26 pm

1 stop25h 41m

$748

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $665. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $745.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $850 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 31% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of November 2025, prices for Chicago to Santiago flights are approximately 25% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Direct flights

None
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
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  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,463 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,477 reviews
Search Avianca flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,028 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $667Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,882 reviews
Search LATAM Airlines flights
DeltaPriceFrom $699Free CancellationRating
7.9
8,002 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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