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Cheap flights from Chicago to Santiago from $286

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:21 am - 7:00 am
MDW
-
SCL
16h 39m2 stops
Delta Logo
11:10 pm - 9:53 am
SCL
-
MDW
13h 43m1 stop
$655Delta
Mon, Jan 12 - Mon, Jan 26
LATAM Airlines Logo
11:19 am - 12:40 pm
ORD
-
SCL
24h 21m3 stops
LATAM Airlines Logo
11:00 pm - 5:41 pm
SCL
-
ORD
19h 41m2 stops
$655LATAM Airlines
Thu, Apr 16 - Sat, May 2
Multiple Airlines Logo
6:05 pm - 6:40 am
ORD
-
SCL
33h 35m2 stops
Multiple Airlines Logo
12:35 pm - 11:22 am
SCL
-
ORD
25h 47m2 stops
$664Multiple Airlines
Mon, Jan 5 - Mon, Jan 26
Multiple Airlines Logo
9:23 am - 12:15 pm
ORD
-
SCL
23h 52m3 stops
Multiple Airlines Logo
11:24 am - 5:52 pm
SCL
-
ORD
33h 28m3 stops
$670Multiple Airlines
Mon, Jan 19 - Wed, Feb 4
LATAM Airlines Logo
10:53 am - 7:40 am
MDW
-
SCL
17h 47m1 stop
LATAM Airlines Logo
11:10 pm - 9:56 am
SCL
-
MDW
13h 46m1 stop
$672LATAM Airlines
Mon, Feb 16 - Mon, Mar 2
Multiple Airlines Logo
6:05 pm - 10:15 pm
ORD
-
SCL
25h 10m2 stops
Multiple Airlines Logo
9:05 pm - 10:38 pm
SCL
-
ORD
28h 33m3 stops
$675Multiple Airlines
Mon, Jan 5 - Mon, Jan 26
Copa Airlines Logo
2:13 pm - 6:00 am
ORD
-
SCL
12h 47m1 stop
Copa Airlines Logo
12:28 pm - 12:24 am
SCL
-
ORD
14h 56m1 stop
$678Copa Airlines
Thu, Jan 15 - Fri, Jan 23
LATAM Airlines Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m1 stop
LATAM Airlines Logo
8:40 pm - 10:29 pm
SCL
-
MDW
27h 49m1 stop
$678LATAM Airlines
Thu, Mar 19 - Sun, Mar 29
LATAM Airlines Logo
5:38 pm - 7:40 am
MDW
-
SCL
12h 02m1 stop
LATAM Airlines Logo
10:35 am - 9:55 am
SCL
-
MDW
25h 20m2 stops
$680LATAM Airlines
Fri, Mar 13 - Sat, Mar 21
Delta Logo
10:48 am - 7:40 am
MDW
-
SCL
17h 52m1 stop
Delta Logo
8:40 pm - 9:51 am
SCL
-
MDW
14h 11m1 stop
$757Delta
Thu, Jan 29 - Wed, Apr 29

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Apr 16
ORD11:19 amChicago O'Hare Intl
24h 21m
3 stops
SCL12:40 pmSantiago Arturo Merino Benitez
May 2
SCL11:00 pmSantiago Arturo Merino Benitez
19h 41m
2 stops
ORD5:41 pmChicago O'Hare Intl
$655
Find similar
LATAM Airlines
Feb 16
MDW10:53 amChicago Midway
17h 47m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 2
SCL11:10 pmSantiago Arturo Merino Benitez
13h 46m
1 stop
MDW9:56 amChicago Midway
$672
Find similar
LATAM Airlines
Mar 19
MDW12:47 pmChicago Midway
16h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 29
SCL8:40 pmSantiago Arturo Merino Benitez
27h 49m
1 stop
MDW10:29 pmChicago Midway
$678
Find similar

Delta flights from Chicago to Santiago

Our best Delta deals on Chicago to Santiago flight tickets
Delta
Jan 12
MDW11:21 amChicago Midway
16h 39m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Jan 26
SCL11:10 pmSantiago Arturo Merino Benitez
13h 43m
1 stop
MDW9:53 amChicago Midway
$655
Find similar
Delta
Jan 29
MDW10:48 amChicago Midway
17h 52m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 29
SCL8:40 pmSantiago Arturo Merino Benitez
14h 11m
1 stop
MDW9:51 amChicago Midway
$757
Find similar
Delta
Jan 30
MDW6:00 amChicago Midway
22h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 29
SCL8:40 pmSantiago Arturo Merino Benitez
14h 11m
1 stop
MDW9:51 amChicago Midway
$761
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 1/12

11:21 am-7:00 am

2 stops16h 39m

Santiago Arturo Merino Benitez

Mon 1/26

11:10 pm-9:53 am

1 stop13h 43m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 4/16

11:19 am-12:40 pm

3 stops24h 21m

Santiago Arturo Merino Benitez

Sat 5/2

11:00 pm-5:41 pm

2 stops19h 41m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/5

6:05 pm-6:40 am

2 stops33h 35m

Santiago Arturo Merino Benitez

Mon 1/26

12:35 pm-11:22 am

2 stops25h 47m

$664

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/19

9:23 am-12:15 pm

3 stops23h 52m

Santiago Arturo Merino Benitez

Wed 2/4

11:24 am-5:52 pm

3 stops33h 28m

$670

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 2/16

10:53 am-7:40 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Mon 3/2

11:10 pm-9:56 am

1 stop13h 46m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/5

6:05 pm-10:15 pm

2 stops25h 10m

Santiago Arturo Merino Benitez

Mon 1/26

9:05 pm-10:38 pm

3 stops28h 33m

$675

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 1/15

2:13 pm-6:00 am

1 stop12h 47m

Santiago Arturo Merino Benitez

Fri 1/23

12:28 pm-12:24 am

1 stop14h 56m

$678

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 3/19

12:47 pm-7:40 am

1 stop16h 53m

Santiago Arturo Merino Benitez

Sun 3/29

8:40 pm-10:29 pm

1 stop27h 49m

$678

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Fri 3/13

5:38 pm-7:40 am

1 stop12h 02m

Santiago Arturo Merino Benitez

Sat 3/21

10:35 am-9:55 am

2 stops25h 20m

$680

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 1/29

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

Wed 4/29

8:40 pm-9:51 am

1 stop14h 11m

$757

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $659. If you don’t want to visit Santiago in September, then you should wait until April to fly from Chicago, when ticket prices are also cheap, with an average price of $775.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $870 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $673 on momondo.

Can stopping save me money on Chicago to Santiago flights?

You could potentially save up to 26% on your flight if you consider stops on a Chicago to Santiago flight.

How have Chicago to Santiago flight prices changed over time?

As of December 2025, prices for Chicago to Santiago flights are approximately 52% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Fastest flight time

12h 22m

Direct flights

None
The fastest flight from Chicago to Santiago takes 12h 22m
There are no direct flights from Chicago to Santiago. There are no popular flight routes from Chicago to Santiago.
Search flight deals

  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?

Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,514 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,478 reviews
Search Avianca flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,090 reviews
Search United Airlines flights
DeltaPriceFrom $626Free CancellationRating
7.9
8,009 reviews
Search Delta flights
Copa AirlinesPriceFrom $638Free CancellationRating
7.6
1,555 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $639Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

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