Cheap flights from Chicago to Santiago from $301

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 9/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

 Logo
6:56 am - 2:46 amORD-SCL
18h 50m2 stops
 Logo
11:29 am - 4:10 pmSCL-ORD
29h 41m2 stops
Tue, Aug 19 - Tue, Aug 26
 Logo
6:56 am - 4:15 amORD-SCL
20h 19m2 stops
 Logo
2:30 pm - 10:22 pmSCL-ORD
32h 52m2 stops
Thu, Aug 21 - Thu, Aug 28
 Logo
6:56 am - 4:15 amORD-SCL
20h 19m2 stops
 Logo
2:30 pm - 11:59 pmSCL-ORD
34h 29m3 stops
Thu, Aug 21 - Thu, Aug 28
 Logo
10:27 am - 11:20 amORD-SCL
22h 53m2 stops
 Logo
12:55 am - 1:15 pmSCL-ORD
14h 20m1 stop
Mon, Sep 15 - Tue, Sep 30
Avianca Logo
2:05 pm - 2:20 pmORD-SCL
21h 15m1 stop
Avianca Logo
12:45 am - 12:15 pmSCL-ORD
14h 30m1 stop
$678Avianca
Find Deal
Tue, Nov 11 - Thu, Nov 20
Avianca Logo
2:35 pm - 4:15 amORD-SCL
12h 40m1 stop
Avianca Logo
11:55 pm - 1:15 pmSCL-ORD
14h 20m1 stop
$715Avianca
Find Deal
Sat, Aug 23 - Sat, Aug 30
LATAM Airlines Logo
6:00 am - 7:00 amMDW-SCL
22h 00m1 stop
LATAM Airlines Logo
11:15 pm - 9:51 amSCL-MDW
13h 36m1 stop
$838LATAM Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 21
LATAM Airlines Logo
10:35 am - 4:30 amMDW-SCL
14h 55m2 stops
LATAM Airlines Logo
8:50 pm - 9:51 amSCL-MDW
16h 01m2 stops
$839LATAM Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 21
Delta Logo
10:35 am - 7:00 amMDW-SCL
17h 25m1 stop
Delta Logo
12:30 am - 4:23 pmSCL-MDW
18h 53m2 stops
$844Delta
Find Deal
Mon, Nov 10 - Thu, Nov 20
Delta Logo
10:35 am - 7:00 amMDW-SCL
17h 25m2 stops
Delta Logo
11:15 pm - 9:21 amSCL-MDW
13h 06m1 stop
$848Delta
Find Deal
Sat, Nov 22 - Mon, Dec 22

LATAM Airlines flights from Chicago to Santiago

Our best LATAM Airlines deals on Chicago to Santiago flight tickets
LATAM Airlines
Nov 11
MDW6:00 amChicago Midway
22h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Nov 21
SCL11:15 pmSantiago Arturo Merino Benitez
13h 36m
1 stop
MDW9:51 amChicago Midway
LATAM Airlines
Nov 11
MDW10:35 amChicago Midway
14h 55m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
Nov 21
SCL8:50 pmSantiago Arturo Merino Benitez
16h 01m
2 stops
MDW9:51 amChicago Midway
LATAM Airlines
Nov 10
MDW1:05 pmChicago Midway
14h 55m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Nov 21
SCL8:50 pmSantiago Arturo Merino Benitez
16h 01m
2 stops
MDW9:51 amChicago Midway

Avianca flights from Chicago to Santiago

Our best Avianca deals on Chicago to Santiago flight tickets
Avianca
Nov 11
ORD2:05 pmChicago O'Hare Intl
21h 15m
1 stop
SCL2:20 pmSantiago Arturo Merino Benitez
Nov 20
SCL12:45 amSantiago Arturo Merino Benitez
14h 30m
1 stop
ORD12:15 pmChicago O'Hare Intl
Avianca
Aug 23
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
Aug 30
SCL11:55 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
Avianca
Sep 14
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Sep 30
SCL12:55 amSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl

See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Chicago to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $684. If you don’t want to visit Santiago in April, then you should wait until October to fly from Chicago, when ticket prices are also cheap, with an average price of $803.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $862 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago for as low as $712 on momondo.

How have Chicago to Santiago flight prices changed over time?

As of July 2025, prices for Chicago to Santiago flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santiago (CHI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santiago

Best Price Found

$301

Fastest flight time

12h 35m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Chicago in the past 72 hours is $301. The best round-trip flight deal from Chicago to Santiago found on momondo in the last 72 hours is $606.
The fastest flight from Chicago to Santiago takes 12h 35m
There are no direct flights from Chicago to Santiago. Popular non-direct routes for this connection are Chicago O'Hare Intl Airport - Santiago Arturo Merino Benitez Airport and Chicago Midway Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is Chicago to Santiago Arturo Merino Benitez by plane?

    The distance between Chicago and Santiago Arturo Merino Benitez is about 5311.0 mi. 12h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago to Santiago?


Best airlines flying from Chicago to Santiago

Compare and see reviews for airlines that fly from Chicago to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $512Free CancellationRating
6.7
2,374 reviews
Search Avianca flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.5
1,474 reviews
Search Copa Airlines flights
DeltaPriceFrom $698Free CancellationRating
8.0
7,952 reviews
Search Delta flights
Air CanadaPriceFrom $707Free CancellationRating
7.1
9,692 reviews
Search Air Canada flights
LATAM AirlinesPriceFrom $734Free CancellationRating
7.5
1,807 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $750Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $782Free CancellationRating
7.4
8,846 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

It is quick and easy to find Chicago to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Flights from Chicago to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Santiago?

momondo helps you find the best flight between Chicago and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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Tue 7/15
Tue 7/22

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