What airlines fly to Panama?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama from Chicago according to our data. Copa Airlines is the first choice among our users, with 78% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to Panama on average per week?

As of July 2025, there are 18 flights per week flying from Chicago to Panama. The most common day of the week flights depart is Wed, with 33% of flights taking off on this day.

What is the cheapest airline that flies from Chicago to Panama?

Avianca, American Airlines, and United Airlines are the most popular carriers operating from Chicago to Panama

How many flights depart from Chicago to Panama on average per day?

The number of flights available between Chicago and Panama is 2 per day as of July 2025. The most frequent departure time is 7:00AM, with 62% of daily flights leaving at noon.

When did momondo last update prices for flights from Chicago to Panama?

Prices for flights from Chicago to Panama refresh daily.

How many operators does momondo search for flights from Chicago to Panama?

As of July 2025, there are 5 operators available to choose from for flights from Chicago to Panama.

How old do you have to be to fly from Chicago to Panama?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$194 Cheap Flights from Chicago to Panama in 2025

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Find the cheapest flights from Chicago to Panama

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

2:35 pm - 12:10 amORD-PTY

9h 35m1 stop

3:19 am - 1:15 pmPTY-ORD

9h 56m1 stop

$446Avianca

Find Deal

Thu, Oct 23 - Sun, Oct 26

3:07 pm - 8:35 pmORD-PTY

5h 28mnonstop

6:45 pm - 12:21 amPTY-ORD

5h 36mnonstop

$451Copa Airlines

Find Deal

Thu, Oct 2 - Sun, Oct 5

9:05 pm - 6:37 pmORD-PTY

21h 32m1 stop

3:30 pm - 7:50 amPTY-ORD

16h 20m1 stop

$456United Airlines

Find Deal

Thu, Oct 2 - Sun, Oct 12

2:35 pm - 12:45 amORD-PTY

10h 10m1 stop

10:05 pm - 1:15 pmPTY-ORD

15h 10m1 stop

$458Avianca

Find Deal

Fri, Sep 12 - Fri, Sep 19

2:07 pm - 7:50 amORD-DAV

16h 43m1 stop

8:32 am - 12:05 amDAV-ORD

16h 33m1 stop

$461Copa Airlines

Find Deal

Wed, Nov 5 - Mon, Nov 10

9:05 pm - 2:14 pmORD-PTY

17h 09m1 stop

10:00 am - 10:41 pmPTY-ORD

12h 41m1 stop

$465United Airlines

Find Deal

Fri, Sep 12 - Sun, Sep 21

6:00 am - 1:52 pmMDW-PTY

6h 52m1 stop

8:05 am - 9:44 pmPTY-MDW

14h 39m1 stop

$465Delta

Find Deal

Wed, Nov 19 - Sun, Nov 23

7:05 am - 2:31 pmORD-PTY

7h 26m1 stop

3:31 pm - 8:43 amPTY-ORD

17h 12m2 stops

$470American Airlines

Find Deal

Fri, Sep 12 - Fri, Sep 19

5:00 am - 2:31 pmORD-PTY

9h 31m1 stop

3:31 pm - 9:29 amPTY-ORD

17h 58m2 stops

$475American Airlines

Find Deal

Thu, Oct 2 - Sun, Oct 5

6:46 pm - 12:55 pmMDW-PTY

18h 09m1 stop

2:10 pm - 12:28 pmPTY-MDW

22h 18m2 stops

$478Delta

Find Deal

Fri, Sep 26 - Mon, Sep 29

Avianca flights from Chicago to Panama

Our best Avianca deals on Chicago to Panama flight tickets

Avianca

Oct 23

ORD2:35 pmChicago O'Hare Intl

9h 35m

1 stop

PTY12:10 amPanama City Tocumen Intl

Oct 26

PTY3:19 amPanama City Tocumen Intl

9h 56m

1 stop

ORD1:15 pmChicago O'Hare Intl

$446

Find similar

Avianca

Sep 12

ORD2:35 pmChicago O'Hare Intl

10h 10m

1 stop

PTY12:45 amPanama City Tocumen Intl

Sep 19

PTY10:05 pmPanama City Tocumen Intl

15h 10m

1 stop

ORD1:15 pmChicago O'Hare Intl

$458

Find similar

Avianca

Oct 8

ORD2:35 pmChicago O'Hare Intl

10h 10m

1 stop

PTY12:45 amPanama City Tocumen Intl

Oct 12

PTY3:20 amPanama City Tocumen Intl

9h 55m

1 stop

ORD1:15 pmChicago O'Hare Intl

$478

Find similar

United Airlines flights from Chicago to Panama

Our best United Airlines deals on Chicago to Panama flight tickets

United Airlines

Oct 2

ORD9:05 pmChicago O'Hare Intl

21h 32m

1 stop

PTY6:37 pmPanama City Tocumen Intl

Oct 12

PTY3:30 pmPanama City Tocumen Intl

16h 20m

1 stop

ORD7:50 amChicago O'Hare Intl

$456

Find similar

United Airlines

Sep 12

ORD9:05 pmChicago O'Hare Intl

17h 09m

1 stop

PTY2:14 pmPanama City Tocumen Intl

Sep 21

PTY10:00 amPanama City Tocumen Intl

12h 41m

1 stop

ORD10:41 pmChicago O'Hare Intl

$465

Find similar

United Airlines

Aug 27

ORD7:00 amChicago O'Hare Intl

11h 37m

1 stop

PTY6:37 pmPanama City Tocumen Intl

Dec 31

PTY4:41 pmPanama City Tocumen Intl

16h 06m

1 stop

ORD7:47 amChicago O'Hare Intl

$534

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Sun 10/26

3:19 am-1:15 pm

1 stop9h 56m

$446

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sun 10/5

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

9:05 pm-6:37 pm

1 stop21h 32m

Panama City Tocumen Intl

Sun 10/12

3:30 pm-7:50 am

1 stop16h 20m

$456

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

2:35 pm-12:45 am

1 stop10h 10m

Panama City Tocumen Intl

Fri 9/19

10:05 pm-1:15 pm

1 stop15h 10m

$458

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Wed 11/5

2:07 pm-7:50 am

1 stop16h 43m

David Enrique Malek

Mon 11/10

8:32 am-12:05 am

1 stop16h 33m

$461

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

9:05 pm-2:14 pm

1 stop17h 09m

Panama City Tocumen Intl

Sun 9/21

10:00 am-10:41 pm

1 stop12h 41m

$465

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 11/19

6:00 am-1:52 pm

1 stop6h 52m

Panama City Tocumen Intl

Sun 11/23

8:05 am-9:44 pm

1 stop14h 39m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

7:05 am-2:31 pm

1 stop7h 26m

Panama City Tocumen Intl

Fri 9/19

3:31 pm-8:43 am

2 stops17h 12m

$470

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

5:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Sun 10/5

3:31 pm-9:29 am

2 stops17h 58m

$475

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 9/26

6:46 pm-12:55 pm

1 stop18h 09m

Panama City Tocumen Intl

Mon 9/29

2:10 pm-12:28 pm

2 stops22h 18m

$478

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How to get the cheapest flight ticket from Chicago to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Chicago, with most prices found around $464. If you don’t want to visit Panama in November, then you should wait until September to fly from Chicago, when ticket prices are also cheap, with an average price of $503.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Chicago. The lowest ticket price found for a Tuesday departure recently was $538. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago to Panama for around $623.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Chicago to Panama when you can find flight prices for as low as $517. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $594 per ticket.

What is the cheapest Chicago to Panama flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $579 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Chicago for as low as $514 on momondo.

What cabin class options are available on Chicago to Panama flights?

There are 3 cabin classes available to choose from on Chicago to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama flights?

You could potentially save up to 90% on your flight if you consider stops on a Chicago to Panama flight.

Cheap Chicago to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama

Best Price Found	$194
Fastest flight time	5h 28m
Direct flights	Every day
Airports in Panama	3 airports

The best one-way flight to Panama from Chicago in the past 72 hours is $194. The best round-trip flight deal from Chicago to Panama found on momondo in the last 72 hours is $446.

The fastest flight from Chicago to Panama takes 5h 28m

Direct flights go from Chicago to Panama every day.

There are 3 airports near Panama: Panama City Marcos A. Gelabert Intl (PAC), Panama City Tocumen Intl (PTY), David Enrique Malek (DAV)

Search flight deals

When did momondo last update prices for flights from Chicago to Panama?
Prices for flights from Chicago to Panama refresh daily.
How many operators does momondo search for flights from Chicago to Panama?
As of July 2025, there are 5 operators available to choose from for flights from Chicago to Panama.
How old do you have to be to fly from Chicago to Panama?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Chicago to Panama?
Based on momondo bookings for flights between Chicago and Panama, the leading plane model is Boeing 737-800, making up 54.47% of the total bookings. Other popular models include Airbus A320neo with 24.80%, Boeing 787-10 Dreamliner with 5.69%, and Boeing 737 MAX 9 with 3.86%.

Best airlines flying from Chicago to Panama

Compare and see reviews for airlines that fly from Chicago to Panama with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $339	Free Cancellation	Rating 6.7 2,388 reviews	Search Avianca flights
Copa Airlines	PriceFrom $464	Free Cancellation	Rating 7.5 1,493 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $478	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $478	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
United Airlines	PriceFrom $478	Free Cancellation	Rating 7.4 8,900 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Chicago.

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

Flights from Chicago to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Chicago.

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Panama

Popular cities in Panama

Flights to Panama Cityfrom $309

Flights to Bocas del Torofrom $593

Flights to Davidfrom $459

Flights to Changuinola

Cheap flights from Chicago to Panama from $194

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

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Filter for what you want

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Find the cheapest flights from Chicago to Panama

Cheap round-trip flights

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Cheap last minute flights

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Avianca flights from Chicago to Panama

Our best Avianca deals on Chicago to Panama flight tickets

United Airlines flights from Chicago to Panama

Our best United Airlines deals on Chicago to Panama flight tickets

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How to get the cheapest flight ticket from Chicago to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Chicago, with most prices found around $464. If you don’t want to visit Panama in November, then you should wait until September to fly from Chicago, when ticket prices are also cheap, with an average price of $503.

What is the cheapest day to depart on your flight to Panama?

What is the cheapest time of day to depart on your flight to Panama?

What is the cheapest Chicago to Panama flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama flight prices

How far in advance should I book a flight to Panama?

What cabin class options are available on Chicago to Panama flights?

There are 3 cabin classes available to choose from on Chicago to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama flights?

You could potentially save up to 90% on your flight if you consider stops on a Chicago to Panama flight.

What is the cheapest airline that flies from Chicago to Panama?

Avianca, American Airlines, and United Airlines are the most popular carriers operating from Chicago to Panama

What airlines fly to Panama?

How many flights depart from Chicago to Panama on average per day?

The number of flights available between Chicago and Panama is 2 per day as of July 2025. The most frequent departure time is 7:00AM, with 62% of daily flights leaving at noon.

How many flights depart from Chicago to Panama on average per week?

As of July 2025, there are 18 flights per week flying from Chicago to Panama. The most common day of the week flights depart is Wed, with 33% of flights taking off on this day.

Cheap Chicago to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama

Best Price Found

Fastest flight time

Direct flights

Airports in Panama

When did momondo last update prices for flights from Chicago to Panama?

How many operators does momondo search for flights from Chicago to Panama?

How old do you have to be to fly from Chicago to Panama?

What documentation or ID do you need to fly to Panama?

What is the most popular plane model from Chicago to Panama?

Best airlines flying from Chicago to Panama

Compare and see reviews for airlines that fly from Chicago to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Panama?

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo