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Cheap flights from Charlotte to Panama from $158

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Charlotte to Panama

Cheap round-trip flights

United Airlines Logo
6:45 am - 1:45 pmCLT-PTY
8h 00m1 stop
United Airlines Logo
8:55 am - 9:36 pmPTY-CLT
12h 41m1 stop
$399United Airlines
Find Deal
Wed, Oct 29 - Wed, Nov 5
United Airlines Logo
6:45 am - 7:38 pmCLT-PTY
12h 53m1 stop
United Airlines Logo
8:55 am - 9:36 pmPTY-CLT
12h 41m1 stop
$403United Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
American Airlines Logo
9:06 pm - 2:03 pmCLT-PTY
17h 57m1 stop
American Airlines Logo
3:15 pm - 10:30 amPTY-CLT
18h 15m1 stop
$404American Airlines
Find Deal
Thu, Oct 9 - Wed, Oct 15
Logo
1:51 pm - 8:37 pmCLT-PTY
7h 46m1 stop
Logo
10:25 am - 6:34 pmPTY-CLT
7h 09m1 stop
$408
Find Deal
Fri, Oct 17 - Mon, Oct 20
American Airlines Logo
9:06 pm - 2:03 pmCLT-PTY
17h 57m1 stop
American Airlines Logo
3:15 pm - 6:26 amPTY-CLT
14h 11m2 stops
$409American Airlines
Find Deal
Thu, Oct 9 - Wed, Oct 15
Delta Logo
9:47 am - 2:12 pmCLT-PTY
28h 25m1 stop
Delta Logo
3:37 pm - 8:41 amPTY-CLT
17h 04m1 stop
$410Delta
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Sun, Nov 9 - Mon, Nov 17
Delta Logo
6:15 am - 12:56 pmCLT-PTY
7h 41m1 stop
Delta Logo
2:21 pm - 11:50 pmPTY-CLT
8h 29m1 stop
$415Delta
Find Deal
Sat, Oct 25 - Tue, Oct 28
American Airlines Logo
5:16 am - 2:03 pmCLT-PTY
9h 47m1 stop
American Airlines Logo
3:15 pm - 7:50 amPTY-CLT
15h 35m2 stops
$420American Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28
United Airlines Logo
6:45 am - 7:38 pmCLT-PTY
12h 53m1 stop
United Airlines Logo
8:55 am - 9:36 pmPTY-CLT
12h 41m1 stop
$423United Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 21
Logo
10:19 am - 9:10 pmCLT-PTY
11h 51m2 stops
Logo
2:55 am - 8:59 pmPTY-CLT
17h 04m2 stops
$449
Find Deal
Sat, Oct 18 - Sat, Oct 25

United Airlines flights from Charlotte to Panama

Our best United Airlines deals on Charlotte to Panama flight tickets
United Airlines
Oct 29
CLT6:45 amCharlotte Douglas
8h 00m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Nov 5
PTY8:55 amPanama City Tocumen Intl
12h 41m
1 stop
CLT9:36 pmCharlotte Douglas
$399
Find similar
United Airlines
Nov 11
CLT6:45 amCharlotte Douglas
12h 53m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Nov 18
PTY8:55 amPanama City Tocumen Intl
12h 41m
1 stop
CLT9:36 pmCharlotte Douglas
$403
Find similar
United Airlines
Nov 11
CLT6:45 amCharlotte Douglas
12h 53m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Nov 21
PTY8:55 amPanama City Tocumen Intl
12h 41m
1 stop
CLT9:36 pmCharlotte Douglas
$423
Find similar

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets
American Airlines
Oct 9
CLT9:06 pmCharlotte Douglas
17h 57m
1 stop
PTY2:03 pmPanama City Tocumen Intl
Oct 15
PTY3:15 pmPanama City Tocumen Intl
18h 15m
1 stop
CLT10:30 amCharlotte Douglas
$404
Find similar
American Airlines
Oct 9
CLT9:06 pmCharlotte Douglas
17h 57m
1 stop
PTY2:03 pmPanama City Tocumen Intl
Oct 15
PTY3:15 pmPanama City Tocumen Intl
14h 11m
2 stops
CLT6:26 amCharlotte Douglas
$409
Find similar
American Airlines
Sep 26
CLT5:18 amCharlotte Douglas
10h 13m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Sep 27
PTY3:31 pmPanama City Tocumen Intl
14h 55m
1 stop
CLT7:26 amCharlotte Douglas
$415
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 10/29

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Wed 11/5

8:55 am-9:36 pm

1 stop12h 41m

$399

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 11/11

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

Tue 11/18

8:55 am-9:36 pm

1 stop12h 41m

$403

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 10/9

9:06 pm-2:03 pm

1 stop17h 57m

Panama City Tocumen Intl

Wed 10/15

3:15 pm-10:30 am

1 stop18h 15m

$404

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 10/17

1:51 pm-8:37 pm

1 stop7h 46m

Panama City Tocumen Intl

Mon 10/20

10:25 am-6:34 pm

1 stop7h 09m

$408

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 10/9

9:06 pm-2:03 pm

1 stop17h 57m

Panama City Tocumen Intl

Wed 10/15

3:15 pm-6:26 am

2 stops14h 11m

$409

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 11/9

9:47 am-2:12 pm

1 stop28h 25m

Panama City Tocumen Intl

Mon 11/17

3:37 pm-8:41 am

1 stop17h 04m

$410

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 10/25

6:15 am-12:56 pm

1 stop7h 41m

Panama City Tocumen Intl

Tue 10/28

2:21 pm-11:50 pm

1 stop8h 29m

$415

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 10/25

5:16 am-2:03 pm

1 stop9h 47m

Panama City Tocumen Intl

Tue 10/28

3:15 pm-7:50 am

2 stops15h 35m

$420

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 11/11

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

Fri 11/21

8:55 am-9:36 pm

1 stop12h 41m

$423

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 10/18

10:19 am-9:10 pm

2 stops11h 51m

Panama City Tocumen Intl

Sat 10/25

2:55 am-8:59 pm

2 stops17h 04m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $510. If you don’t want to visit Panama in October, then you should wait until May to fly from Charlotte, when ticket prices are also cheap, with an average price of $511.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Charlotte. The lowest ticket price found for a Wednesday departure recently was $502. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to Panama for around $650.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Charlotte to Panama when you can find flight prices for as low as $478. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $844 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $577 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $459 on momondo.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Direct flights

None
There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.
Search flight deals

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

    Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

  • How old do you have to be to fly from Charlotte Douglas Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $436Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
American AirlinesPriceFrom $441Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $465Free CancellationRating
7.9
7,956 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

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