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Cheap flights from Charlotte to Panama from $172

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charlotte to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:45 pm - 12:46 pm
CLT
-
PTY
17h 01m
1 stop
American Airlines Logo
1:49 pm - 10:57 pm
PTY
-
CLT
8h 08m
1 stop
$409American Airlines
Mon, May 11 - Tue, May 19
American Airlines Logo
8:45 pm - 12:46 pm
CLT
-
PTY
17h 01m
1 stop
American Airlines Logo
1:49 pm - 6:26 am
PTY
-
CLT
15h 37m
2 stops
$413American Airlines
Mon, May 11 - Tue, May 19
American Airlines Logo
8:45 pm - 12:46 pm
CLT
-
PTY
17h 01m
1 stop
American Airlines Logo
1:49 pm - 10:57 pm
PTY
-
CLT
8h 08m
1 stop
$419American Airlines
Mon, Apr 13 - Fri, Apr 17
American Airlines Logo
8:45 pm - 12:46 pm
CLT
-
PTY
17h 01m
1 stop
American Airlines Logo
1:49 pm - 6:26 am
PTY
-
CLT
15h 37m
2 stops
$423American Airlines
Mon, May 11 - Tue, May 19
American Airlines Logo
5:05 am - 12:46 pm
CLT
-
PTY
8h 41m
1 stop
American Airlines Logo
1:49 pm - 10:57 pm
PTY
-
CLT
8h 08m
1 stop
$429American Airlines
Sun, May 10 - Fri, May 15
American Airlines Logo
6:15 am - 12:40 pm
CLT
-
PTY
7h 25m
1 stop
American Airlines Logo
1:49 pm - 10:57 pm
PTY
-
CLT
8h 08m
1 stop
$434American Airlines
Wed, Apr 1 - Wed, Apr 15
Multiple Airlines Logo
7:00 am - 10:30 am
CLT
-
PTY
28h 30m
3 stops
Multiple Airlines Logo
2:55 pm - 12:07 pm
PTY
-
CLT
20h 12m
2 stops
$438Multiple Airlines
Fri, Mar 20 - Wed, Mar 25
American Airlines Logo
6:10 am - 12:46 pm
CLT
-
PTY
7h 36m
1 stop
American Airlines Logo
1:49 pm - 6:26 am
PTY
-
CLT
15h 37m
2 stops
$443American Airlines
Sat, Apr 18 - Tue, Apr 21
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
19h 00m
2 stops
Multiple Airlines Logo
5:50 pm - 12:07 pm
PTY
-
CLT
17h 17m
2 stops
$447Multiple Airlines
Tue, Mar 10 - Tue, Mar 17
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
19h 00m
2 stops
Multiple Airlines Logo
5:50 pm - 12:07 pm
PTY
-
CLT
17h 17m
2 stops
$448Multiple Airlines
Tue, Mar 10 - Tue, Mar 17

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets
American Airlines
May 11
CLT8:45 pmCharlotte Douglas
17h 01m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 19
PTY1:49 pmPanama City Tocumen Intl
8h 08m
1 stop
CLT10:57 pmCharlotte Douglas
$409
American Airlines
May 11
CLT8:45 pmCharlotte Douglas
17h 01m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 19
PTY1:49 pmPanama City Tocumen Intl
15h 37m
2 stops
CLT6:26 amCharlotte Douglas
$413
American Airlines
Apr 13
CLT8:45 pmCharlotte Douglas
17h 01m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 17
PTY1:49 pmPanama City Tocumen Intl
8h 08m
1 stop
CLT10:57 pmCharlotte Douglas
$419

Delta flights from Charlotte to Panama

Our best Delta deals on Charlotte to Panama flight tickets
Delta
Feb 24
CLT5:25 amCharlotte Douglas
8h 25m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 11
PTY2:28 pmPanama City Tocumen Intl
17h 12m
1 stop
CLT8:40 amCharlotte Douglas
$459
Delta
Mar 1
CLT6:59 pmCharlotte Douglas
18h 51m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 11
PTY2:28 pmPanama City Tocumen Intl
17h 12m
1 stop
CLT8:40 amCharlotte Douglas
$465
Delta
Feb 24
CLT5:25 amCharlotte Douglas
8h 25m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 13
PTY2:28 pmPanama City Tocumen Intl
17h 12m
1 stop
CLT8:40 amCharlotte Douglas
$600

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 5/11

8:45 pm-12:46 pm

1 stop17h 01m

Panama City Tocumen Intl

Tue 5/19

1:49 pm-10:57 pm

1 stop8h 08m

$409

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 5/11

8:45 pm-12:46 pm

1 stop17h 01m

Panama City Tocumen Intl

Tue 5/19

1:49 pm-6:26 am

2 stops15h 37m

$413

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 4/13

8:45 pm-12:46 pm

1 stop17h 01m

Panama City Tocumen Intl

Fri 4/17

1:49 pm-10:57 pm

1 stop8h 08m

$419

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 5/11

8:45 pm-12:46 pm

1 stop17h 01m

Panama City Tocumen Intl

Tue 5/19

1:49 pm-6:26 am

2 stops15h 37m

$423

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 5/10

5:05 am-12:46 pm

1 stop8h 41m

Panama City Tocumen Intl

Fri 5/15

1:49 pm-10:57 pm

1 stop8h 08m

$429

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 4/1

6:15 am-12:40 pm

1 stop7h 25m

Panama City Tocumen Intl

Wed 4/15

1:49 pm-10:57 pm

1 stop8h 08m

$434

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 3/20

7:00 am-10:30 am

3 stops28h 30m

Panama City Tocumen Intl

Wed 3/25

2:55 pm-12:07 pm

2 stops20h 12m

$438

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 4/18

6:10 am-12:46 pm

1 stop7h 36m

Panama City Tocumen Intl

Tue 4/21

1:49 pm-6:26 am

2 stops15h 37m

$443

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 3/10

7:00 am-1:00 am

2 stops19h 00m

Panama City Tocumen Intl

Tue 3/17

5:50 pm-12:07 pm

2 stops17h 17m

$447

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 3/10

7:00 am-1:00 am

2 stops19h 00m

Panama City Tocumen Intl

Tue 3/17

5:50 pm-12:07 pm

2 stops17h 17m

$448

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $496. If you don’t want to visit Panama in September, then you should wait until October to fly from Charlotte, when ticket prices are also cheap, with an average price of $508.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $569 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $310 on momondo.

Can stopping save me money on Charlotte to Panama flights?

You could potentially save up to 62% on your flight if you consider stops on a Charlotte to Panama flight.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Fastest flight time

6h 55m

Direct flights

None
The fastest flight from Charlotte to Panama takes 6h 55m
There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.
Search flight deals

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

    Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

  • How old do you have to be to fly from Charlotte Douglas Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $435Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights
DeltaPriceFrom $447Free CancellationRating
7.9
8,186 reviews
Search Delta flights
United AirlinesPriceFrom $467Free CancellationRating
7.4
9,283 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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