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Cheap flights from Charlotte to Panama from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 12/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charlotte to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
18h 00m2 stops
Multiple Airlines Logo
5:50 pm - 12:22 pm
PTY
-
CLT
18h 32m2 stops
$417Multiple Airlines
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
10:34 am - 1:00 am
CLT
-
PTY
14h 26m2 stops
Multiple Airlines Logo
2:55 pm - 12:22 pm
PTY
-
CLT
21h 27m2 stops
$437Multiple Airlines
Thu, Jan 1 - Wed, Feb 4
Multiple Airlines Logo
7:00 am - 12:40 am
CLT
-
PTY
17h 40m2 stops
Multiple Airlines Logo
2:55 pm - 12:22 pm
PTY
-
CLT
21h 27m2 stops
$443Multiple Airlines
Mon, Feb 2 - Fri, Feb 6
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
18h 00m2 stops
Multiple Airlines Logo
2:55 pm - 12:20 pm
PTY
-
CLT
21h 25m2 stops
$453Multiple Airlines
Thu, Feb 5 - Thu, Feb 12
United Airlines Logo
6:33 am - 2:45 pm
CLT
-
PTY
8h 12m1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
CLT
13h 04m1 stop
$468United Airlines
Wed, Mar 4 - Mon, Mar 9
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
18h 00m2 stops
Multiple Airlines Logo
2:55 am - 6:48 pm
PTY
-
CLT
15h 53m2 stops
$469Multiple Airlines
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
6:00 am - 12:40 am
CLT
-
PTY
18h 40m2 stops
Multiple Airlines Logo
5:50 pm - 12:22 pm
PTY
-
CLT
18h 32m2 stops
$470Multiple Airlines
Wed, Jan 21 - Sat, Jan 31
Multiple Airlines Logo
7:00 am - 12:40 am
CLT
-
PTY
17h 40m2 stops
Multiple Airlines Logo
5:50 pm - 12:22 pm
PTY
-
CLT
18h 32m2 stops
$471Multiple Airlines
Mon, Jan 19 - Wed, Jan 21
American Airlines Logo
5:00 am - 3:15 pm
CLT
-
PTY
10h 15m1 stop
American Airlines Logo
4:05 pm - 6:37 am
PTY
-
CLT
14h 32m2 stops
$472American Airlines
Fri, Feb 27 - Thu, Mar 5
United Airlines Logo
4:45 pm - 5:07 pm
CLT
-
PTY
24h 22m1 stop
United Airlines Logo
4:41 pm - 10:47 am
PTY
-
CLT
18h 06m1 stop
$477United Airlines
Sun, Feb 8 - Thu, Feb 12

United Airlines flights from Charlotte to Panama

Our best United Airlines deals on Charlotte to Panama flight tickets
United Airlines
Mar 4
CLT6:33 amCharlotte Douglas
8h 12m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Mar 9
PTY7:55 amPanama City Tocumen Intl
13h 04m
1 stop
CLT9:59 pmCharlotte Douglas
$468
Find similar
United Airlines
Feb 8
CLT4:45 pmCharlotte Douglas
24h 22m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Feb 12
PTY4:41 pmPanama City Tocumen Intl
18h 06m
1 stop
CLT10:47 amCharlotte Douglas
$477
Find similar
United Airlines
Feb 15
CLT11:34 amCharlotte Douglas
27h 11m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 28
PTY4:41 pmPanama City Tocumen Intl
18h 06m
1 stop
CLT10:47 amCharlotte Douglas
$497
Find similar

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets
American Airlines
Feb 27
CLT5:00 amCharlotte Douglas
10h 15m
1 stop
PTY3:15 pmPanama City Tocumen Intl
Mar 5
PTY4:05 pmPanama City Tocumen Intl
14h 32m
2 stops
CLT6:37 amCharlotte Douglas
$472
Find similar
American Airlines
Jan 29
CLT5:15 amCharlotte Douglas
8h 12m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 2
PTY4:50 pmPanama City Tocumen Intl
14h 41m
2 stops
CLT7:31 amCharlotte Douglas
$532
Find similar
American Airlines
Jan 24
CLT10:17 pmCharlotte Douglas
15h 10m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 31
PTY5:00 pmPanama City Tocumen Intl
16h 19m
1 stop
CLT9:19 amCharlotte Douglas
$552
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 1/22

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 1/25

5:50 pm-12:22 pm

2 stops18h 32m

$417

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 1/1

10:34 am-1:00 am

2 stops14h 26m

Panama City Tocumen Intl

Wed 2/4

2:55 pm-12:22 pm

2 stops21h 27m

$437

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 2/2

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

Fri 2/6

2:55 pm-12:22 pm

2 stops21h 27m

$443

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 2/5

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Thu 2/12

2:55 pm-12:20 pm

2 stops21h 25m

$453

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 3/4

6:33 am-2:45 pm

1 stop8h 12m

Panama City Tocumen Intl

Mon 3/9

7:55 am-9:59 pm

1 stop13h 04m

$468

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 1/22

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 1/25

2:55 am-6:48 pm

2 stops15h 53m

$469

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 1/21

6:00 am-12:40 am

2 stops18h 40m

Panama City Tocumen Intl

Sat 1/31

5:50 pm-12:22 pm

2 stops18h 32m

$470

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 1/19

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

Wed 1/21

5:50 pm-12:22 pm

2 stops18h 32m

$471

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 2/27

5:00 am-3:15 pm

1 stop10h 15m

Panama City Tocumen Intl

Thu 3/5

4:05 pm-6:37 am

2 stops14h 32m

$472

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 2/8

4:45 pm-5:07 pm

1 stop24h 22m

Panama City Tocumen Intl

Thu 2/12

4:41 pm-10:47 am

1 stop18h 06m

$477

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $496. If you don’t want to visit Panama in September, then you should wait until May to fly from Charlotte, when ticket prices are also cheap, with an average price of $507.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Charlotte. The lowest ticket price found for a Wednesday departure recently was $502. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to Panama for around $650.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Charlotte to Panama when you can find flight prices for as low as $478. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $844 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $565 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $312 on momondo.

Can stopping save me money on Charlotte to Panama flights?

You could potentially save up to 69% on your flight if you consider stops on a Charlotte to Panama flight.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Fastest flight time

8h 12m

Direct flights

None
The fastest flight from Charlotte to Panama takes 8h 12m
There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.
Search flight deals

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

    Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

  • How old do you have to be to fly from Charlotte Douglas Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $435Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
United AirlinesPriceFrom $453Free CancellationRating
7.4
9,102 reviews
Search United Airlines flights
DeltaPriceFrom $465Free CancellationRating
7.9
8,014 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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