What airlines fly to Panama?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Panama from Charlotte according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Charlotte Douglas to Panama?

United Airlines and Delta are the most popular carriers operating from Charlotte Douglas to Panama

When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

As of September 2026, there are 3 operators available to choose from for flights from Charlotte Douglas Airport to Panama.

How old do you have to be to fly from Charlotte Douglas Airport to Panama?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$177 Cheap Flights from Charlotte to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charlotte to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:48 am - 8:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

13h 14m1 stop Newark

10:00 am - 9:07 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

11h 07m1 stop Newark

$409United Airlines

Mon, Nov 23 - Mon, Dec 7

8:10 am - 8:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

11h 52m2 stops Chicago O'Hare Intl Newark

10:00 am - 10:22 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

24h 22m2 stops Newark Washington, D.C. Dulles Intl

$413United Airlines

Mon, Nov 23 - Mon, Dec 7

8:10 am - 8:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

11h 52m2 stops Chicago O'Hare Intl Newark

10:00 am - 9:07 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

11h 07m1 stop Newark

$413United Airlines

Mon, Nov 23 - Mon, Dec 7

6:45 am - 12:59 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 14m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:54 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 30m1 stop Atlanta Hartsfield-Jackson

$589Delta

Tue, Oct 20 - Fri, Oct 23

7:40 am - 1:59 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

6h 19m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:57 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 28m1 stop Atlanta Hartsfield-Jackson

$589Delta

Sat, Nov 7 - Tue, Nov 10

6:30 am - 2:03 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 33m1 stop Atlanta Hartsfield-Jackson

8:00 am - 11:56 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

15h 56m1 stop Atlanta Hartsfield-Jackson

$589Delta

Tue, Dec 8 - Tue, Dec 22

6:00 am - 1:26 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 26m1 stop Miami

2:26 pm - 6:32 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

16h 06m2 stops Miami Washington, D.C. Reagan-National

$613American Airlines

Fri, Jan 29 - Tue, Feb 2

6:00 am - 3:55 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

9h 55m1 stop Miami

2:26 pm - 8:35 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

18h 09m1 stop Miami

$620American Airlines

Fri, Jan 29 - Tue, Feb 2

6:00 am - 8:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

14h 02m1 stop Newark

4:41 pm - 9:59 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

29h 18m1 stop Houston George Bush Intcntl

$620Copa Airlines

Tue, Nov 10 - Sun, Nov 15

6:30 am - 5:12 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

10h 42m1 stop Houston George Bush Intcntl

8:55 am - 9:52 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

12h 57m1 stop Houston George Bush Intcntl

$658Copa Airlines

Thu, Jan 21 - Tue, Jan 26

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 7:31 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

14h 31m2 stops Washington, D.C. Dulles Intl Newark

9:45 am - 11:56 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

13h 11m2 stops Newark Washington, D.C. Dulles Intl

$633United Airlines

Sat, Oct 3 - Mon, Oct 19

9:54 am - 7:31 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

10h 37m1 stop Newark

3:30 pm - 2:20 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

21h 50m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$633United Airlines

Sat, Oct 3 - Mon, Oct 19

7:00 am - 7:31 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

13h 31m1 stop Newark

9:45 am - 9:06 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

22h 21m1 stop Newark

$637United Airlines

Sat, Oct 3 - Mon, Oct 19

5:30 am - 12:58 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

8h 28m1 stop Atlanta Hartsfield-Jackson

2:23 pm - 11:59 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 36m1 stop Atlanta Hartsfield-Jackson

$648Delta

Fri, Oct 2 - Mon, Oct 5

7:07 am - 12:16 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

6h 09m1 stop Miami

2:02 pm - 8:25 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

17h 23m1 stop Miami

$755American Airlines

Fri, Oct 2 - Mon, Oct 12

10:44 pm - 1:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

15h 18m1 stop Miami

2:02 pm - 8:25 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

17h 23m1 stop Miami

$758American Airlines

Mon, Oct 5 - Mon, Oct 12

5:20 am - 12:16 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 56m1 stop Miami

2:02 pm - 6:27 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

15h 25m2 stops Miami Washington, D.C. Reagan-National

$763American Airlines

Fri, Oct 2 - Mon, Oct 5

6:45 am - 6:37 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

12h 52m1 stop Houston George Bush Intcntl

9:45 am - 9:15 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

10h 30m1 stop Newark

$774Copa Airlines

Sat, Oct 3 - Mon, Oct 5

7:07 am - 12:16 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

6h 09m1 stop Miami

2:02 pm - 7:55 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

16h 53m2 stops Miami Washington, D.C. Reagan-National

$915GOL

Sat, Oct 3 - Mon, Oct 5

9:59 pm - 5:00 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

20h 01m2 stops Miami Bogotá El Dorado

5:30 am - 7:55 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

25h 25m3 stops San Salvador El Salvador Intl Miami Philadelphia

$918Multiple Airlines

Fri, Oct 2 - Sun, Oct 4

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Delta flights from Charlotte to Panama

Our best Delta deals on Charlotte to Panama flight tickets

Delta

Nov 7

CLT7:40 amCharlotte Douglas

6h 19m

1 stop

PTY1:59 pmPanama City Tocumen Intl

Nov 10

PTY3:29 pmPanama City Tocumen Intl

8h 28m

1 stop

CLT11:57 pmCharlotte Douglas

$589

Delta

Nov 7

CLT7:40 amCharlotte Douglas

6h 19m

1 stop

PTY1:59 pmPanama City Tocumen Intl

Nov 10

PTY3:29 pmPanama City Tocumen Intl

8h 28m

1 stop

CLT11:57 pmCharlotte Douglas

$591

Delta

Oct 29

CLT6:45 amCharlotte Douglas

7h 14m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Nov 5

PTY3:24 pmPanama City Tocumen Intl

8h 30m

1 stop

CLT11:54 pmCharlotte Douglas

$595

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets

American Airlines

Feb 5

CLT6:00 amCharlotte Douglas

9h 55m

1 stop

PTY3:55 pmPanama City Tocumen Intl

Feb 14

PTY4:04 pmPanama City Tocumen Intl

8h 11m

1 stop

CLT12:15 amCharlotte Douglas

$644

American Airlines

Feb 24

CLT8:45 pmCharlotte Douglas

16h 36m

1 stop

PTY1:21 pmPanama City Tocumen Intl

Feb 28

PTY4:04 pmPanama City Tocumen Intl

17h 10m

1 stop

CLT9:14 amCharlotte Douglas

$649

American Airlines

Oct 2

CLT7:07 amCharlotte Douglas

6h 09m

1 stop

PTY12:16 pmPanama City Tocumen Intl

Oct 12

PTY2:02 pmPanama City Tocumen Intl

17h 23m

1 stop

CLT8:25 amCharlotte Douglas

$755

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Mon 11/23

6:48 am-8:02 pm

1 stop13h 14m

Panama City Tocumen Intl

Mon 12/7

10:00 am-9:07 pm

1 stop11h 07m

$409

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Mon 11/23

8:10 am-8:02 pm

2 stops11h 52m

Panama City Tocumen Intl

Mon 12/7

10:00 am-10:22 am

2 stops24h 22m

$413

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Mon 11/23

8:10 am-8:02 pm

2 stops11h 52m

Panama City Tocumen Intl

Mon 12/7

10:00 am-9:07 pm

1 stop11h 07m

$413

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Tue 10/20

6:45 am-12:59 pm

1 stop7h 14m

Panama City Tocumen Intl

Fri 10/23

2:24 pm-11:54 pm

1 stop8h 30m

$589

Quickest round-trip

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Sat 11/7

7:40 am-1:59 pm

1 stop6h 19m

Panama City Tocumen Intl

Tue 11/10

3:29 pm-11:57 pm

1 stop8h 28m

$589

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Tue 12/8

6:30 am-2:03 pm

1 stop7h 33m

Panama City Tocumen Intl

Tue 12/22

8:00 am-11:56 pm

1 stop15h 56m

$589

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Fri 1/29

6:00 am-1:26 pm

1 stop7h 26m

Panama City Tocumen Intl

Tue 2/2

2:26 pm-6:32 am

2 stops16h 06m

$613

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Fri 1/29

6:00 am-3:55 pm

1 stop9h 55m

Panama City Tocumen Intl

Tue 2/2

2:26 pm-8:35 am

1 stop18h 09m

$620

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Tue 11/10

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Sun 11/15

4:41 pm-9:59 pm

1 stop29h 18m

$620

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Thu 1/21

6:30 am-5:12 pm

1 stop10h 42m

Panama City Tocumen Intl

Tue 1/26

8:55 am-9:52 pm

1 stop12h 57m

$658

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $541. If you don’t want to visit Panama in April, then you should wait until May to fly from Charlotte, when ticket prices are also cheap, with an average price of $577.

How far in advance should I book a flight from Charlotte to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $657 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $520 on momondo.

Can stopping save me money on Charlotte to Panama flights?

You could potentially save up to 32% on your flight if you consider stops on a Charlotte to Panama flight.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Best Price Found	$177
Fastest flight time	7h 14m
Direct flights	None

The best one-way flight to Panama from Charlotte in the past 72 hours is $177. The best round-trip flight deal from Charlotte to Panama found on momondo in the last 72 hours is $409.

The fastest flight from Charlotte to Panama takes 7h 14m

There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.

Search flight deals

Frequently asked questions about flying from Charlotte to Panama

When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?
Prices for flights from Charlotte Douglas Airport to Panama refresh daily.
How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?
As of September 2026, there are 3 operators available to choose from for flights from Charlotte Douglas Airport to Panama.
How old do you have to be to fly from Charlotte Douglas Airport to Panama?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $431	Free Cancellation	Rating 7.8 8,608 reviews	Search Delta flights
United Airlines	PriceFrom $467	Free Cancellation	Rating 7.4 10,261 reviews	Search United Airlines flights
American Airlines	PriceFrom $487	Free Cancellation	Rating 7.0 12,097 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

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Popular cities in Panama

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Cheap flights from Charlotte to Panama from $177

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 12/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Charlotte to Panama

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Delta flights from Charlotte to Panama

Our best Delta deals on Charlotte to Panama flight tickets

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets

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Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

What is the cheapest month to fly to Panama?

How far in advance should I book a flight from Charlotte to Panama?

Can stopping save me money on Charlotte to Panama flights?

What is the cheapest airline that flies from Charlotte Douglas to Panama?

What airlines fly to Panama?

Cheap Charlotte to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Charlotte to Panama

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Charlotte flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year