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Cheap flights from Charlotte to Panama from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Charlotte to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:48 pm - 2:15 pm
CLT
-
PTY
26h 27m
2 stops
Multiple Airlines Logo
10:10 am - 11:43 am
PTY
-
CLT
24h 33m
2 stops
$443Multiple Airlines
Sun, May 17 - Wed, May 20
Multiple Airlines Logo
6:30 am - 12:35 am
CLT
-
PTY
19h 05m
2 stops
Multiple Airlines Logo
3:10 pm - 11:43 am
PTY
-
CLT
19h 33m
2 stops
$447Multiple Airlines
Thu, Apr 30 - Thu, May 7
Multiple Airlines Logo
6:30 am - 1:55 am
CLT
-
PTY
20h 25m
3 stops
Multiple Airlines Logo
3:10 pm - 11:43 am
PTY
-
CLT
19h 33m
2 stops
$448Multiple Airlines
Thu, Apr 30 - Thu, May 7
American Airlines Logo
10:25 pm - 2:20 pm
CLT
-
PTY
16h 55m
1 stop
American Airlines Logo
3:20 pm - 11:52 pm
PTY
-
CLT
7h 32m
1 stop
$449American Airlines
Thu, Sep 3 - Tue, Sep 8
Multiple Airlines Logo
12:48 pm - 10:30 am
CLT
-
PTY
22h 42m
3 stops
Multiple Airlines Logo
10:10 am - 11:43 am
PTY
-
CLT
24h 33m
2 stops
$455Multiple Airlines
Sun, May 17 - Wed, May 20
Multiple Airlines Logo
12:48 pm - 7:20 pm
CLT
-
PTY
7h 32m
1 stop
Multiple Airlines Logo
8:10 am - 5:13 pm
PTY
-
CLT
8h 03m
1 stop
$458Multiple Airlines
Thu, May 7 - Thu, May 28
Multiple Airlines Logo
6:30 am - 3:54 pm
CLT
-
PTY
10h 24m
1 stop
Multiple Airlines Logo
9:33 pm - 11:43 am
PTY
-
CLT
13h 10m
1 stop
$466Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
2:28 pm - 8:35 pm
CLT
-
PTY
7h 07m
1 stop
Multiple Airlines Logo
9:33 pm - 8:18 am
PTY
-
CLT
9h 45m
1 stop
$472Multiple Airlines
Mon, Apr 20 - Sat, Apr 25
Delta Logo
5:30 am - 1:02 pm
CLT
-
PTY
8h 32m
1 stop
Delta Logo
2:15 pm - 11:53 pm
PTY
-
CLT
8h 38m
1 stop
$474Delta
Wed, May 6 - Thu, May 28
Multiple Airlines Logo
7:00 am - 12:35 am
CLT
-
PTY
18h 35m
2 stops
Multiple Airlines Logo
10:10 am - 8:37 pm
PTY
-
CLT
33h 27m
2 stops
$476Multiple Airlines
Mon, Apr 13 - Fri, Apr 17

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets
American Airlines
Sep 3
CLT10:25 pmCharlotte Douglas
16h 55m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Sep 8
PTY3:20 pmPanama City Tocumen Intl
7h 32m
1 stop
CLT11:52 pmCharlotte Douglas
$449
American Airlines
Sep 6
CLT5:17 amCharlotte Douglas
10h 03m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Sep 18
PTY3:40 pmPanama City Tocumen Intl
14h 28m
1 stop
CLT7:08 amCharlotte Douglas
$479
American Airlines
Sep 6
CLT10:25 pmCharlotte Douglas
16h 55m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Sep 18
PTY3:40 pmPanama City Tocumen Intl
13h 47m
2 stops
CLT6:27 amCharlotte Douglas
$483

Delta flights from Charlotte to Panama

Our best Delta deals on Charlotte to Panama flight tickets
Delta
May 6
CLT6:46 amCharlotte Douglas
7h 16m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Jun 1
PTY2:15 pmPanama City Tocumen Intl
8h 38m
1 stop
CLT11:53 pmCharlotte Douglas
$474
Delta
May 6
CLT6:46 amCharlotte Douglas
7h 16m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 27
PTY2:15 pmPanama City Tocumen Intl
19h 50m
1 stop
CLT11:05 amCharlotte Douglas
$480
Delta
May 12
CLT9:41 amCharlotte Douglas
28h 09m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 28
PTY2:15 pmPanama City Tocumen Intl
8h 38m
1 stop
CLT11:53 pmCharlotte Douglas
$481

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 5/17

12:48 pm-2:15 pm

2 stops26h 27m

Panama City Tocumen Intl

Wed 5/20

10:10 am-11:43 am

2 stops24h 33m

$443

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/30

6:30 am-12:35 am

2 stops19h 05m

Panama City Tocumen Intl

Thu 5/7

3:10 pm-11:43 am

2 stops19h 33m

$447

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/30

6:30 am-1:55 am

3 stops20h 25m

Panama City Tocumen Intl

Thu 5/7

3:10 pm-11:43 am

2 stops19h 33m

$448

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 9/3

10:25 pm-2:20 pm

1 stop16h 55m

Panama City Tocumen Intl

Tue 9/8

3:20 pm-11:52 pm

1 stop7h 32m

$449

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 5/17

12:48 pm-10:30 am

3 stops22h 42m

Panama City Tocumen Intl

Wed 5/20

10:10 am-11:43 am

2 stops24h 33m

$455
Quickest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 5/7

12:48 pm-7:20 pm

1 stop7h 32m

Panama City Tocumen Intl

Thu 5/28

8:10 am-5:13 pm

1 stop8h 03m

$458

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/30

6:30 am-3:54 pm

1 stop10h 24m

Panama City Tocumen Intl

Sun 5/3

9:33 pm-11:43 am

1 stop13h 10m

$466

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 4/20

2:28 pm-8:35 pm

1 stop7h 07m

Panama City Tocumen Intl

Sat 4/25

9:33 pm-8:18 am

1 stop9h 45m

$472

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 5/6

5:30 am-1:02 pm

1 stop8h 32m

Panama City Tocumen Intl

Thu 5/28

2:15 pm-11:53 pm

1 stop8h 38m

$474

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 4/13

7:00 am-12:35 am

2 stops18h 35m

Panama City Tocumen Intl

Fri 4/17

10:10 am-8:37 pm

2 stops33h 27m

$476

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $492. If you don’t want to visit Panama in September, then you should wait until May to fly from Charlotte, when ticket prices are also cheap, with an average price of $503.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $564 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $288 on momondo.

Can stopping save me money on Charlotte to Panama flights?

You could potentially save up to 51% on your flight if you consider stops on a Charlotte to Panama flight.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Fastest flight time

6h 04m

Direct flights

None
The fastest flight from Charlotte to Panama takes 6h 04m
There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.
Search flight deals

Frequently asked questions about flying from Charlotte to Panama

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

    Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

  • How old do you have to be to fly from Charlotte Douglas Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $431Free CancellationRating
7.9
8,369 reviews
Search Delta flights
American AirlinesPriceFrom $435Free CancellationRating
7.1
11,549 reviews
Search American Airlines flights
United AirlinesPriceFrom $467Free CancellationRating
7.4
9,533 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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