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Cheap flights from Charlotte to Panama from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charlotte to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
10:25 am - 8:35 pm
CLT
-
PTY
11h 10m
1 stop
Copa Airlines Logo
10:29 pm - 9:44 am
PTY
-
CLT
10h 15m
1 stop
$533Copa Airlines
Fri, Aug 21 - Fri, Aug 28
Copa Airlines Logo
11:00 am - 7:31 pm
CLT
-
PTY
9h 31m
1 stop
Copa Airlines Logo
3:41 pm - 10:52 am
PTY
-
CLT
18h 11m
1 stop
$538Copa Airlines
Tue, Oct 20 - Wed, Oct 28
Copa Airlines Logo
6:00 am - 8:35 pm
CLT
-
PTY
15h 35m
1 stop
Copa Airlines Logo
10:29 pm - 9:44 am
PTY
-
CLT
10h 15m
1 stop
$539Copa Airlines
Sun, Sep 6 - Fri, Sep 18
Copa Airlines Logo
7:00 am - 7:31 pm
CLT
-
PTY
13h 31m
1 stop
Copa Airlines Logo
3:41 pm - 1:50 pm
PTY
-
CLT
21h 09m
2 stops
$542Copa Airlines
Tue, Oct 20 - Wed, Oct 28
United Airlines Logo
7:00 am - 7:31 pm
CLT
-
PTY
13h 31m
1 stop
United Airlines Logo
9:45 am - 11:59 pm
PTY
-
CLT
13h 14m
2 stops
$543United Airlines
Mon, Sep 28 - Thu, Oct 1
Copa Airlines Logo
7:55 pm - 8:35 pm
CLT
-
PTY
24h 40m
1 stop
Copa Airlines Logo
10:29 pm - 9:44 am
PTY
-
CLT
11h 15m
1 stop
$552Copa Airlines
Thu, Nov 26 - Mon, Nov 30
United Airlines Logo
7:00 am - 7:31 pm
CLT
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 10:54 am
PTY
-
CLT
18h 24m
1 stop
$569United Airlines
Fri, Sep 4 - Thu, Sep 10
United Airlines Logo
5:36 pm - 7:31 pm
CLT
-
PTY
26h 55m
2 stops
United Airlines Logo
3:30 pm - 5:17 pm
PTY
-
CLT
24h 47m
2 stops
$573United Airlines
Sun, Sep 6 - Fri, Sep 18
American Airlines Logo
9:30 pm - 12:39 pm
CLT
-
PTY
16h 09m
1 stop
American Airlines Logo
1:39 pm - 9:55 am
PTY
-
CLT
19h 16m
1 stop
$580American Airlines
Mon, Aug 17 - Sat, Aug 22
American Airlines Logo
8:19 pm - 1:36 pm
CLT
-
PTY
17h 17m
1 stop
American Airlines Logo
2:50 pm - 6:29 am
PTY
-
CLT
15h 39m
2 stops
$583American Airlines
Thu, Nov 26 - Sat, Dec 5

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United Airlines flights from Charlotte to Panama

Our best United Airlines deals on Charlotte to Panama flight tickets
United Airlines
Sep 28
CLT10:25 amCharlotte Douglas
10h 06m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Oct 1
PTY10:00 amPanama City Tocumen Intl
23h 08m
2 stops
CLT10:08 amCharlotte Douglas
$543
United Airlines
Sep 4
CLT7:00 amCharlotte Douglas
13h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Sep 10
PTY3:30 pmPanama City Tocumen Intl
18h 24m
1 stop
CLT10:54 amCharlotte Douglas
$569
United Airlines
Sep 6
CLT5:36 pmCharlotte Douglas
26h 55m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Sep 18
PTY3:30 pmPanama City Tocumen Intl
24h 47m
2 stops
CLT5:17 pmCharlotte Douglas
$573

American Airlines flights from Charlotte to Panama

Our best American Airlines deals on Charlotte to Panama flight tickets
American Airlines
Aug 17
CLT9:30 pmCharlotte Douglas
16h 09m
1 stop
PTY12:39 pmPanama City Tocumen Intl
Aug 22
PTY1:39 pmPanama City Tocumen Intl
19h 16m
1 stop
CLT9:55 amCharlotte Douglas
$580
American Airlines
Aug 17
CLT10:32 pmCharlotte Douglas
15h 07m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Aug 22
PTY1:39 pmPanama City Tocumen Intl
19h 16m
1 stop
CLT9:55 amCharlotte Douglas
$585
American Airlines
Aug 13
CLT5:20 amCharlotte Douglas
8h 19m
1 stop
PTY12:39 pmPanama City Tocumen Intl
Aug 20
PTY1:39 pmPanama City Tocumen Intl
18h 01m
1 stop
CLT8:40 amCharlotte Douglas
$589

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 8/21

10:25 am-8:35 pm

1 stop11h 10m

Panama City Tocumen Intl

Fri 8/28

10:29 pm-9:44 am

1 stop10h 15m

$533

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 10/20

11:00 am-7:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Wed 10/28

3:41 pm-10:52 am

1 stop18h 11m

$538

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 9/6

6:00 am-8:35 pm

1 stop15h 35m

Panama City Tocumen Intl

Fri 9/18

10:29 pm-9:44 am

1 stop10h 15m

$539

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 10/20

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Wed 10/28

3:41 pm-1:50 pm

2 stops21h 09m

$542

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 9/28

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 10/1

9:45 am-11:59 pm

2 stops13h 14m

$543

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/26

7:55 pm-8:35 pm

1 stop24h 40m

Panama City Tocumen Intl

Mon 11/30

10:29 pm-9:44 am

1 stop11h 15m

$552

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 9/4

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 9/10

3:30 pm-10:54 am

1 stop18h 24m

$569

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 9/6

5:36 pm-7:31 pm

2 stops26h 55m

Panama City Tocumen Intl

Fri 9/18

3:30 pm-5:17 pm

2 stops24h 47m

$573

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 8/17

9:30 pm-12:39 pm

1 stop16h 09m

Panama City Tocumen Intl

Sat 8/22

1:39 pm-9:55 am

1 stop19h 16m

$580

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/26

8:19 pm-1:36 pm

1 stop17h 17m

Panama City Tocumen Intl

Sat 12/5

2:50 pm-6:29 am

2 stops15h 39m

$583

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charlotte to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of December is, on average, the cheapest month to fly to Panama from Charlotte, with most prices found around $221. If you don’t want to visit Panama in December, then you should wait until October to fly from Charlotte, when ticket prices are also cheap, with an average price of $395.

How far in advance should I book a flight from Charlotte to Panama?

You are more likely to see cheaper flights to Panama from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $604 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Charlotte for as low as $388 on momondo.

Can stopping save me money on Charlotte to Panama flights?

You could potentially save up to 64% on your flight if you consider stops on a Charlotte to Panama flight.

Cheap Charlotte to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Panama

Fastest flight time

6h 04m

Direct flights

None
The fastest flight from Charlotte to Panama takes 6h 04m
There are no direct flights from Charlotte to Panama. There are no popular flight routes from Charlotte to Panama.
Search flight deals

Frequently asked questions about flying from Charlotte to Panama

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Panama?

    Prices for flights from Charlotte Douglas Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Panama?

  • How old do you have to be to fly from Charlotte Douglas Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to Panama

Compare and see reviews for airlines that fly from Charlotte to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $428Free CancellationRating
7.1
11,769 reviews
Search American Airlines flights
DeltaPriceFrom $431Free CancellationRating
7.8
8,452 reviews
Search Delta flights
United AirlinesPriceFrom $467Free CancellationRating
7.4
9,926 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to Panama for you.

Can I find flights from Charlotte to Panama with flexible booking policies on momondo?

Flights from Charlotte to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to Panama?

momondo helps you find the best flight between Charlotte and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

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