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Cheap flights from Charleston to Santo Domingo from $154

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santo Domingo departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charleston to Santo Domingo

Cheap round-trip flights

Spirit Airlines Logo
8:44 pm - 2:56 pmCHS-SDQ
18h 12m2 stops
Spirit Airlines Logo
3:47 pm - 9:25 amSDQ-CHS
17h 38m1 stop
$373Spirit Airlines
Find Deal
Wed, Oct 15 - Sat, Oct 25
JetBlue Logo
9:40 am - 1:24 pmCHS-SDQ
27h 44m1 stop
JetBlue Logo
8:10 am - 6:05 pmSDQ-CHS
9h 55m1 stop
$411JetBlue
Find Deal
Wed, Oct 15 - Sat, Oct 25
JetBlue Logo
9:40 am - 1:24 pmCHS-SDQ
27h 44m1 stop
JetBlue Logo
8:10 am - 6:05 pmSDQ-CHS
9h 55m1 stop
$428JetBlue
Find Deal
Sun, Oct 12 - Sat, Oct 25
Delta Logo
7:00 am - 6:00 pmCHS-SDQ
11h 00m1 stop
Delta Logo
2:47 pm - 11:51 pmSDQ-CHS
9h 04m1 stop
$441Delta
Find Deal
Fri, Aug 29 - Fri, Sep 5
Delta Logo
1:00 pm - 12:52 amCHS-SDQ
11h 52m2 stops
Delta Logo
6:00 am - 4:58 pmSDQ-CHS
10h 58m1 stop
$445Delta
Find Deal
Wed, Sep 3 - Fri, Sep 5
American Airlines Logo
5:45 am - 5:23 pmCHS-SDQ
10h 38m2 stops
American Airlines Logo
1:12 pm - 11:56 pmSDQ-CHS
11h 44m2 stops
$454American Airlines
Find Deal
Wed, Nov 19 - Sat, Nov 22
American Airlines Logo
6:36 pm - 9:25 amCHS-SDQ
14h 49m2 stops
American Airlines Logo
7:00 am - 12:05 amSDQ-CHS
17h 05m2 stops
$455American Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 25
Logo
8:17 pm - 11:56 amCHS-SDQ
15h 39m2 stops
Logo
5:05 pm - 10:59 pmSDQ-CHS
29h 54m3 stops
$586
Find Deal
Fri, Aug 29 - Fri, Sep 5
Logo
10:38 am - 4:00 pmCHS-SDQ
29h 22m3 stops
Logo
5:05 pm - 10:59 pmSDQ-CHS
29h 54m3 stops
$621
Find Deal
Fri, Aug 29 - Fri, Sep 5
United Airlines Logo
6:00 am - 2:10 pmCHS-SDQ
8h 10m1 stop
United Airlines Logo
1:10 pm - 11:30 pmSDQ-CHS
10h 20m1 stop
$847United Airlines
Find Deal
Sat, Aug 30 - Sat, Sep 6

Spirit Airlines flights from Charleston to Santo Domingo

Our best Spirit Airlines deals on Charleston to Santo Domingo flight tickets
Spirit Airlines
Oct 15
CHS8:44 pmCharleston
18h 12m
2 stops
SDQ2:56 pmSanto Domingo Las Americas
Oct 25
SDQ3:47 pmSanto Domingo Las Americas
17h 38m
1 stop
CHS9:25 amCharleston
$373
Find similar
Spirit Airlines
Nov 19
CHS11:40 amCharleston
29h 10m
3 stops
SDQ5:50 pmSanto Domingo Las Americas
Nov 22
SDQ6:55 pmSanto Domingo Las Americas
22h 50m
2 stops
CHS4:45 pmCharleston
$809
Find similar

JetBlue flights from Charleston to Santo Domingo

Our best JetBlue deals on Charleston to Santo Domingo flight tickets
JetBlue
Oct 15
CHS9:40 amCharleston
27h 44m
1 stop
SDQ1:24 pmSanto Domingo Las Americas
Oct 25
SDQ8:10 amSanto Domingo Las Americas
9h 55m
1 stop
CHS6:05 pmCharleston
$411
Find similar
JetBlue
Oct 12
CHS9:40 amCharleston
27h 44m
1 stop
SDQ1:24 pmSanto Domingo Las Americas
Oct 25
SDQ8:10 amSanto Domingo Las Americas
9h 55m
1 stop
CHS6:05 pmCharleston
$428
Find similar
JetBlue
Nov 19
CHS10:40 amCharleston
20h 50m
2 stops
SDQ8:30 amSanto Domingo Las Americas
Nov 21
SDQ4:18 amSanto Domingo Las Americas
13h 34m
1 stop
CHS4:52 pmCharleston
$484
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 10/15

8:44 pm-2:56 pm

2 stops18h 12m

Santo Domingo Las Americas

Sat 10/25

3:47 pm-9:25 am

1 stop17h 38m

$373

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 10/15

9:40 am-1:24 pm

1 stop27h 44m

Santo Domingo Las Americas

Sat 10/25

8:10 am-6:05 pm

1 stop9h 55m

$411

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 10/12

9:40 am-1:24 pm

1 stop27h 44m

Santo Domingo Las Americas

Sat 10/25

8:10 am-6:05 pm

1 stop9h 55m

$428

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 8/29

7:00 am-6:00 pm

1 stop11h 00m

Santo Domingo Las Americas

Fri 9/5

2:47 pm-11:51 pm

1 stop9h 04m

$441

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 9/3

1:00 pm-12:52 am

2 stops11h 52m

Santo Domingo Las Americas

Fri 9/5

6:00 am-4:58 pm

1 stop10h 58m

$445

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 11/19

5:45 am-5:23 pm

2 stops10h 38m

Santo Domingo Las Americas

Sat 11/22

1:12 pm-11:56 pm

2 stops11h 44m

$454

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 10/12

6:36 pm-9:25 am

2 stops14h 49m

Santo Domingo Las Americas

Sat 10/25

7:00 am-12:05 am

2 stops17h 05m

$455

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 8/29

8:17 pm-11:56 am

2 stops15h 39m

Santo Domingo Las Americas

Fri 9/5

5:05 pm-10:59 pm

3 stops29h 54m

$586

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 8/29

10:38 am-4:00 pm

3 stops29h 22m

Santo Domingo Las Americas

Fri 9/5

5:05 pm-10:59 pm

3 stops29h 54m

$621

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sat 8/30

6:00 am-2:10 pm

1 stop8h 10m

Santo Domingo Las Americas

Sat 9/6

1:10 pm-11:30 pm

1 stop10h 20m

$847

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Charleston to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until January to fly from Charleston, when ticket prices are also cheap, with an average price of $463.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $391. The most expensive day to fly to Santo Domingo is Monday, with ticket prices averaging around $760.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is at noon when flights can be purchased for as low as $257. Try not to purchase tickets in the afternoon because they tend to be around $637. Of course, these prices can vary depending on the time of year and what airport you fly to.

How have Charleston to Santo Domingo flight prices changed over time?

When to book flights from Charleston to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santo Domingo (CHS to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santo Domingo

Best Price Found

$154

Fastest flight time

8h 10m

Direct flights

None

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Charleston in the past 72 hours is $154. The best round-trip flight deal from Charleston to Santo Domingo found on momondo in the last 72 hours is $373.
The fastest flight from Charleston to Santo Domingo takes 8h 10m
There are no direct flights from Charleston to Santo Domingo. Popular non-direct route for this connection is Charleston Airport - Santo Domingo Las Americas Airport.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
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  • How far is Charleston to Santo Domingo Las Americas by plane?

    There are 1165.2 mi between Charleston and Santo Domingo Las Americas. By plane, this route typically takes 8h 10m.

  • When did momondo last update prices for flights from Charleston Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Charleston Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Charleston Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Charleston to Santo Domingo?

Best airlines flying from Charleston to Santo Domingo

Compare and see reviews for airlines that fly from Charleston to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $320Free CancellationRating
8.0
7,983 reviews
Search Delta flights
American AirlinesPriceFrom $410Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santo Domingo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Santo Domingo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Charleston with this policy.

How can momondo help me find flights from Charleston to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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