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Cheap flights from Charleston to Santo Domingo from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santo Domingo departing on 7/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
5:27 pm - 11:59 pm
CHS
-
SDQ
6h 32m
1 stop
JetBlue Logo
5:01 am - 4:47 pm
SDQ
-
CHS
11h 46m
1 stop
$380JetBlue
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
6:00 am - 6:44 pm
CHS
-
SDQ
12h 44m
1 stop
American Airlines Logo
2:00 pm - 11:54 pm
SDQ
-
CHS
9h 54m
1 stop
$388American Airlines
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
7:48 pm - 9:25 am
CHS
-
SDQ
13h 37m
2 stops
American Airlines Logo
2:00 pm - 11:54 pm
SDQ
-
CHS
9h 54m
1 stop
$393American Airlines
Thu, Aug 20 - Mon, Aug 24
Delta Logo
5:25 pm - 1:35 am
CHS
-
SDQ
7h 10m
1 stop
Delta Logo
8:45 pm - 11:00 am
SDQ
-
CHS
15h 15m
1 stop
$424Delta
Mon, Nov 23 - Fri, Jan 22
American Airlines Logo
7:48 pm - 1:22 pm
CHS
-
SDQ
17h 34m
2 stops
American Airlines Logo
10:27 am - 11:54 pm
SDQ
-
CHS
13h 27m
2 stops
$429American Airlines
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
6:00 am - 3:24 pm
CHS
-
SDQ
9h 24m
1 stop
American Airlines Logo
2:00 pm - 11:54 pm
SDQ
-
CHS
9h 54m
1 stop
$438American Airlines
Sun, Sep 6 - Tue, Sep 8
American Airlines Logo
1:07 pm - 9:25 am
CHS
-
SDQ
20h 18m
2 stops
American Airlines Logo
4:24 pm - 11:16 am
SDQ
-
CHS
18h 52m
2 stops
$443American Airlines
Sun, Sep 6 - Tue, Sep 8
Delta Logo
2:30 pm - 1:35 am
CHS
-
SDQ
10h 05m
1 stop
Delta Logo
8:45 pm - 11:00 am
SDQ
-
CHS
15h 15m
1 stop
$460Delta
Tue, Nov 24 - Fri, Jan 22
Delta Logo
1:00 pm - 1:35 am
CHS
-
SDQ
11h 35m
2 stops
Delta Logo
8:45 pm - 3:39 pm
SDQ
-
CHS
19h 54m
2 stops
$465Delta
Mon, Nov 23 - Fri, Jan 22
Delta Logo
5:25 pm - 1:35 am
CHS
-
SDQ
7h 10m
1 stop
Delta Logo
8:45 pm - 1:46 pm
SDQ
-
CHS
18h 01m
1 stop
$507Delta
Mon, Nov 23 - Wed, Jan 20

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Delta flights from Charleston to Santo Domingo

Our best Delta deals on Charleston to Santo Domingo flight tickets
Delta
Nov 23
CHS5:25 pmCharleston
7h 10m
1 stop
SDQ1:35 amSanto Domingo Las Americas
Jan 22
SDQ8:45 pmSanto Domingo Las Americas
15h 15m
1 stop
CHS11:00 amCharleston
$424
Delta
Nov 24
CHS2:30 pmCharleston
10h 05m
1 stop
SDQ1:35 amSanto Domingo Las Americas
Jan 22
SDQ8:45 pmSanto Domingo Las Americas
15h 15m
1 stop
CHS11:00 amCharleston
$460
Delta
Nov 23
CHS1:00 pmCharleston
11h 35m
2 stops
SDQ1:35 amSanto Domingo Las Americas
Jan 22
SDQ8:45 pmSanto Domingo Las Americas
19h 54m
2 stops
CHS3:39 pmCharleston
$465

American Airlines flights from Charleston to Santo Domingo

Our best American Airlines deals on Charleston to Santo Domingo flight tickets
American Airlines
Aug 20
CHS6:00 amCharleston
12h 44m
1 stop
SDQ6:44 pmSanto Domingo Las Americas
Aug 24
SDQ2:00 pmSanto Domingo Las Americas
9h 54m
1 stop
CHS11:54 pmCharleston
$388
American Airlines
Aug 20
CHS7:48 pmCharleston
13h 37m
2 stops
SDQ9:25 amSanto Domingo Las Americas
Aug 24
SDQ2:00 pmSanto Domingo Las Americas
9h 54m
1 stop
CHS11:54 pmCharleston
$393
American Airlines
Aug 20
CHS7:48 pmCharleston
17h 34m
2 stops
SDQ1:22 pmSanto Domingo Las Americas
Aug 24
SDQ10:27 amSanto Domingo Las Americas
13h 27m
2 stops
CHS11:54 pmCharleston
$429

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Charleston to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/20

5:27 pm-11:59 pm

1 stop6h 32m

Santo Domingo Las Americas

Mon 8/24

5:01 am-4:47 pm

1 stop11h 46m

$380

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/20

6:00 am-6:44 pm

1 stop12h 44m

Santo Domingo Las Americas

Mon 8/24

2:00 pm-11:54 pm

1 stop9h 54m

$388

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/20

7:48 pm-9:25 am

2 stops13h 37m

Santo Domingo Las Americas

Mon 8/24

2:00 pm-11:54 pm

1 stop9h 54m

$393

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 11/23

5:25 pm-1:35 am

1 stop7h 10m

Santo Domingo Las Americas

Fri 1/22

8:45 pm-11:00 am

1 stop15h 15m

$424

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 8/20

7:48 pm-1:22 pm

2 stops17h 34m

Santo Domingo Las Americas

Mon 8/24

10:27 am-11:54 pm

2 stops13h 27m

$429

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 9/6

6:00 am-3:24 pm

1 stop9h 24m

Santo Domingo Las Americas

Tue 9/8

2:00 pm-11:54 pm

1 stop9h 54m

$438

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sun 9/6

1:07 pm-9:25 am

2 stops20h 18m

Santo Domingo Las Americas

Tue 9/8

4:24 pm-11:16 am

2 stops18h 52m

$443

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Tue 11/24

2:30 pm-1:35 am

1 stop10h 05m

Santo Domingo Las Americas

Fri 1/22

8:45 pm-11:00 am

1 stop15h 15m

$460

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 11/23

1:00 pm-1:35 am

2 stops11h 35m

Santo Domingo Las Americas

Fri 1/22

8:45 pm-3:39 pm

2 stops19h 54m

$465

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Mon 11/23

5:25 pm-1:35 am

1 stop7h 10m

Santo Domingo Las Americas

Wed 1/20

8:45 pm-1:46 pm

1 stop18h 01m

$507

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Charleston to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in November, then you should wait until January to fly from Charleston, when ticket prices are also cheap, with an average price of $398.

Can stopping save me money on Charleston to Santo Domingo flights?

You could potentially save up to 23% on your flight if you consider stops on a Charleston to Santo Domingo flight.

How have Charleston to Santo Domingo flight prices changed over time?

When to book flights from Charleston to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santo Domingo (CHS to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santo Domingo

Fastest flight time

6h 44m

Direct flights

None
The fastest flight from Charleston to Santo Domingo takes 6h 44m
There are no direct flights from Charleston to Santo Domingo. There are no popular flight routes from Charleston to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Charleston to Santo Domingo

  • How far is Charleston to Santo Domingo Las Americas by plane?

    There are 1165.2 mi between Charleston and Santo Domingo Las Americas. By plane, this route typically takes 6h 44m.

  • When did momondo last update prices for flights from Charleston Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Charleston Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Charleston Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Charleston to Santo Domingo?

Best airlines flying from Charleston to Santo Domingo

Compare and see reviews for airlines that fly from Charleston to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $332Free CancellationRating
7.1
11,741 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santo Domingo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Santo Domingo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Charleston with this policy.

How can momondo help me find flights from Charleston to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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