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Cheap flights from Buffalo to Santiago de los Caballeros from $321

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santiago de los Caballeros departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Buffalo to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:45 pm - 3:20 am
BUF
-
STI
6h 35m1 stop
JetBlue Logo
9:35 am - 6:49 pm
STI
-
BUF
10h 14m1 stop
$321JetBlue
Mon, Feb 2 - Thu, Feb 5
JetBlue Logo
3:25 pm - 4:31 am
BUF
-
STI
12h 06m1 stop
JetBlue Logo
11:16 am - 9:09 pm
STI
-
BUF
10h 53m1 stop
$328JetBlue
Sun, Feb 8 - Thu, Feb 12
United Airlines Logo
8:30 am - 11:51 pm
BUF
-
STI
14h 21m2 stops
United Airlines Logo
12:52 pm - 11:44 pm
STI
-
BUF
11h 52m2 stops
$402United Airlines
Sun, Feb 8 - Thu, Feb 12
United Airlines Logo
8:30 am - 11:51 pm
BUF
-
STI
14h 21m2 stops
United Airlines Logo
6:00 am - 8:29 pm
STI
-
BUF
15h 29m2 stops
$451United Airlines
Mon, Feb 2 - Thu, Feb 5
JetBlue Logo
8:50 am - 6:48 pm
BUF
-
STI
8h 58m1 stop
JetBlue Logo
11:53 pm - 10:35 am
STI
-
BUF
11h 42m1 stop
$707JetBlue
Fri, Dec 26 - Tue, Dec 30
American Airlines Logo
5:22 pm - 2:24 pm
BUF
-
STI
20h 02m2 stops
American Airlines Logo
6:00 am - 11:32 pm
STI
-
BUF
18h 32m2 stops
$717American Airlines
Fri, Dec 26 - Tue, Dec 30
United Airlines Logo
7:48 pm - 2:53 pm
BUF
-
STI
18h 05m2 stops
United Airlines Logo
4:00 pm - 10:55 pm
STI
-
BUF
7h 55m1 stop
$935United Airlines
Fri, Dec 26 - Tue, Dec 30
American Airlines Logo
6:00 am - 5:27 pm
BUF
-
STI
10h 27m3 stops
American Airlines Logo
3:24 pm - 11:32 pm
STI
-
BUF
9h 08m2 stops
$2,755American Airlines
Fri, Dec 26 - Tue, Dec 30

United Airlines flights from Buffalo to Santiago de los Caballeros

Our best United Airlines deals on Buffalo to Santiago de los Caballeros flight tickets
United Airlines
Feb 8
BUF8:30 amBuffalo
14h 21m
2 stops
STI11:51 pmSantiago de los Caballeros
Feb 12
STI12:52 pmSantiago de los Caballeros
11h 52m
2 stops
BUF11:44 pmBuffalo
$402
Find similar
United Airlines
Feb 2
BUF8:30 amBuffalo
14h 21m
2 stops
STI11:51 pmSantiago de los Caballeros
Feb 5
STI6:00 amSantiago de los Caballeros
15h 29m
2 stops
BUF8:29 pmBuffalo
$451
Find similar
United Airlines
Dec 26
BUF7:48 pmBuffalo
18h 05m
2 stops
STI2:53 pmSantiago de los Caballeros
Dec 30
STI4:00 pmSantiago de los Caballeros
7h 55m
1 stop
BUF10:55 pmBuffalo
$935
Find similar

JetBlue flights from Buffalo to Santiago de los Caballeros

Our best JetBlue deals on Buffalo to Santiago de los Caballeros flight tickets
JetBlue
Feb 2
BUF7:45 pmBuffalo
6h 35m
1 stop
STI3:20 amSantiago de los Caballeros
Feb 5
STI9:35 amSantiago de los Caballeros
10h 14m
1 stop
BUF6:49 pmBuffalo
$321
Find similar
JetBlue
Feb 8
BUF3:25 pmBuffalo
12h 06m
1 stop
STI4:31 amSantiago de los Caballeros
Feb 12
STI11:16 amSantiago de los Caballeros
10h 53m
1 stop
BUF9:09 pmBuffalo
$328
Find similar
JetBlue
Dec 26
BUF8:50 amBuffalo
8h 58m
1 stop
STI6:48 pmSantiago de los Caballeros
Dec 30
STI11:53 pmSantiago de los Caballeros
11h 42m
1 stop
BUF10:35 amBuffalo
$707
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Mon 2/2

7:45 pm-3:20 am

1 stop6h 35m

Santiago de los Caballeros

Thu 2/5

9:35 am-6:49 pm

1 stop10h 14m

$321

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 2/8

3:25 pm-4:31 am

1 stop12h 06m

Santiago de los Caballeros

Thu 2/12

11:16 am-9:09 pm

1 stop10h 53m

$328

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 2/8

8:30 am-11:51 pm

2 stops14h 21m

Santiago de los Caballeros

Thu 2/12

12:52 pm-11:44 pm

2 stops11h 52m

$402

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Mon 2/2

8:30 am-11:51 pm

2 stops14h 21m

Santiago de los Caballeros

Thu 2/5

6:00 am-8:29 pm

2 stops15h 29m

$451

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 12/26

8:50 am-6:48 pm

1 stop8h 58m

Santiago de los Caballeros

Tue 12/30

11:53 pm-10:35 am

1 stop11h 42m

$707

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 12/26

5:22 pm-2:24 pm

2 stops20h 02m

Santiago de los Caballeros

Tue 12/30

6:00 am-11:32 pm

2 stops18h 32m

$717

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 12/26

7:48 pm-2:53 pm

2 stops18h 05m

Santiago de los Caballeros

Tue 12/30

4:00 pm-10:55 pm

1 stop7h 55m

$935

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 12/26

6:00 am-5:27 pm

3 stops10h 27m

Santiago de los Caballeros

Tue 12/30

3:24 pm-11:32 pm

2 stops9h 08m

$2,755

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Buffalo to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Buffalo is in September. Flight prices, which tend to average around $443, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of September, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $452.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Buffalo to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $463. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Buffalo to Santiago de los Caballeros for around $1,251.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Buffalo to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $463. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $664 per ticket.

When to book flights from Buffalo to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santiago de los Caballeros (BUF to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santiago de los Caballeros

Fastest flight time

6h 35m

Direct flights

None
The fastest flight from Buffalo to Santiago de los Caballeros takes 6h 35m
There are no direct flights from Buffalo to Santiago de los Caballeros. There are no popular flight routes from Buffalo to Santiago de los Caballeros.
Search flight deals

  • How far is Buffalo to Santiago de los Caballeros by plane?

    A flight from Buffalo to Santiago de los Caballeros will travel around 1686.6 mi. In terms of flight time, this usually takes a little over 6h 35m.

  • When did momondo last update prices for flights from Buffalo Airport to Santiago de los Caballeros Airport?

    Prices for flights from Buffalo Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Buffalo Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santiago de los Caballeros?

Best airlines flying from Buffalo to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Buffalo to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $416Free CancellationRating
7.2
2,898 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from Buffalo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Buffalo to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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