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Cheap flights from Buffalo to Santiago de los Caballeros from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santiago de los Caballeros departing on 12/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:15 am - 11:54 pmBUF-STI
11h 39m1 stop
Delta Logo
8:11 pm - 10:37 amSTI-BUF
15h 26m1 stop
$360Delta
Find Deal
dom., mar. 1 - jue., mar. 5
JetBlue Logo
3:25 pm - 4:31 amBUF-STI
12h 06m1 stop
JetBlue Logo
9:25 am - 9:36 pmSTI-BUF
13h 11m1 stop
$367JetBlue
Find Deal
vie., ene. 16 - lun., ene. 26
JetBlue Logo
12:45 pm - 8:39 pmBUF-STI
6h 54m1 stop
JetBlue Logo
4:51 am - 11:50 amSTI-BUF
7h 59m1 stop
$392JetBlue
Find Deal
dom., mar. 1 - mié., mar. 4
American Airlines Logo
6:08 am - 9:03 pmBUF-STI
13h 55m2 stops
American Airlines Logo
8:00 am - 12:07 amSTI-BUF
17h 07m2 stops
$406American Airlines
Find Deal
dom., mar. 1 - jue., mar. 5
American Airlines Logo
7:00 am - 8:03 pmBUF-STI
13h 03m2 stops
American Airlines Logo
3:35 pm - 9:09 amSTI-BUF
17h 34m2 stops
$471American Airlines
Find Deal
jue., abr. 2 - lun., abr. 13
American Airlines Logo
11:00 am - 12:13 pmBUF-STI
25h 13m2 stops
American Airlines Logo
7:00 am - 11:26 pmSTI-BUF
17h 26m2 stops
$482American Airlines
Find Deal
vie., oct. 31 - vie., nov. 14
American Airlines Logo
11:52 am - 12:13 pmBUF-STI
24h 21m2 stops
American Airlines Logo
7:00 am - 10:49 pmSTI-BUF
16h 49m2 stops
$484American Airlines
Find Deal
vie., oct. 31 - vie., nov. 14
JetBlue Logo
3:25 pm - 4:31 amBUF-STI
12h 06m1 stop
JetBlue Logo
4:10 am - 1:50 pmSTI-BUF
10h 40m1 stop
$488JetBlue
Find Deal
vie., ene. 16 - dom., ene. 25
United Airlines Logo
6:00 am - 12:57 pmBUF-STI
6h 57m1 stop
United Airlines Logo
2:07 pm - 10:37 pmSTI-BUF
8h 30m1 stop
$528United Airlines
Find Deal
jue., abr. 2 - lun., abr. 13
United Airlines Logo
6:00 am - 1:53 pmBUF-STI
7h 53m1 stop
United Airlines Logo
4:00 pm - 6:46 pmSTI-BUF
27h 46m2 stops
$594United Airlines
Find Deal
vie., oct. 31 - vie., nov. 14

Delta flights from Buffalo to Santiago de los Caballeros

Our best Delta deals on Buffalo to Santiago de los Caballeros flight tickets
Delta
Mar 1
BUF11:15 amBuffalo
11h 39m
1 stop
STI11:54 pmSantiago de los Caballeros
Mar 5
STI8:11 pmSantiago de los Caballeros
15h 26m
1 stop
BUF10:37 amBuffalo
$360
Find similar
Delta
Apr 3
BUF7:00 amBuffalo
11h 16m
1 stop
STI6:16 pmSantiago de los Caballeros
Apr 16
STI1:30 pmSantiago de los Caballeros
10h 26m
1 stop
BUF11:56 pmBuffalo
$522
Find similar
Delta
Oct 31
BUF11:15 amBuffalo
7h 51m
1 stop
STI7:06 pmSantiago de los Caballeros
Nov 14
STI2:31 pmSantiago de los Caballeros
10h 28m
1 stop
BUF11:59 pmBuffalo
$531
Find similar

JetBlue flights from Buffalo to Santiago de los Caballeros

Our best JetBlue deals on Buffalo to Santiago de los Caballeros flight tickets
JetBlue
Jan 16
BUF3:25 pmBuffalo
12h 06m
1 stop
STI4:31 amSantiago de los Caballeros
Jan 26
STI9:25 amSantiago de los Caballeros
13h 11m
1 stop
BUF9:36 pmBuffalo
$367
Find similar
JetBlue
Mar 1
BUF12:45 pmBuffalo
6h 54m
1 stop
STI8:39 pmSantiago de los Caballeros
Mar 4
STI4:51 amSantiago de los Caballeros
7h 59m
1 stop
BUF11:50 amBuffalo
$392
Find similar
JetBlue
Jan 16
BUF3:25 pmBuffalo
12h 06m
1 stop
STI4:31 amSantiago de los Caballeros
Jan 25
STI4:10 amSantiago de los Caballeros
10h 40m
1 stop
BUF1:50 pmBuffalo
$488
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 6, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

dom. 3/1

11:15 am-11:54 pm

1 stop11h 39m

Santiago de los Caballeros

jue. 3/5

8:11 pm-10:37 am

1 stop15h 26m

$360

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

vie. 1/16

3:25 pm-4:31 am

1 stop12h 06m

Santiago de los Caballeros

lun. 1/26

9:25 am-9:36 pm

1 stop13h 11m

$367

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

dom. 3/1

12:45 pm-8:39 pm

1 stop6h 54m

Santiago de los Caballeros

mié. 3/4

4:51 am-11:50 am

1 stop7h 59m

$392

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

dom. 3/1

6:08 am-9:03 pm

2 stops13h 55m

Santiago de los Caballeros

jue. 3/5

8:00 am-12:07 am

2 stops17h 07m

$406

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

jue. 4/2

7:00 am-8:03 pm

2 stops13h 03m

Santiago de los Caballeros

lun. 4/13

3:35 pm-9:09 am

2 stops17h 34m

$471

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

vie. 10/31

11:00 am-12:13 pm

2 stops25h 13m

Santiago de los Caballeros

vie. 11/14

7:00 am-11:26 pm

2 stops17h 26m

$482

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

vie. 10/31

11:52 am-12:13 pm

2 stops24h 21m

Santiago de los Caballeros

vie. 11/14

7:00 am-10:49 pm

2 stops16h 49m

$484

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

vie. 1/16

3:25 pm-4:31 am

1 stop12h 06m

Santiago de los Caballeros

dom. 1/25

4:10 am-1:50 pm

1 stop10h 40m

$488

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

jue. 4/2

6:00 am-12:57 pm

1 stop6h 57m

Santiago de los Caballeros

lun. 4/13

2:07 pm-10:37 pm

1 stop8h 30m

$528

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

vie. 10/31

6:00 am-1:53 pm

1 stop7h 53m

Santiago de los Caballeros

vie. 11/14

4:00 pm-6:46 pm

2 stops27h 46m

$594

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Buffalo to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Buffalo is in September. Flight prices, which tend to average around $443, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of September, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $452.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Buffalo to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $463. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Buffalo to Santiago de los Caballeros for around $1,251.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Buffalo to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $463. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $664 per ticket.

When to book flights from Buffalo to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santiago de los Caballeros (BUF to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Buffalo to Santiago de los Caballeros. There are no popular flight routes from Buffalo to Santiago de los Caballeros.
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  • How far is Buffalo to Santiago de los Caballeros by plane?

    A flight from Buffalo to Santiago de los Caballeros will travel around 1686.6 mi. In terms of flight time, this usually takes a little over 6h 11m.

  • When did momondo last update prices for flights from Buffalo Airport to Santiago de los Caballeros Airport?

    Prices for flights from Buffalo Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Buffalo Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santiago de los Caballeros?

Best airlines flying from Buffalo to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Buffalo to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $426Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from Buffalo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Buffalo to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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