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Cheap flights from Buffalo to Santiago de los Caballeros from $318

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santiago de los Caballeros departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Buffalo to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:51 am - 12:50 amBUF-STI
11h 59m1 stop
Delta Logo
6:38 am - 2:58 pmSTI-BUF
9h 20m1 stop
$360Delta
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Sun, Jan 25 - Wed, Jan 28
JetBlue Logo
3:25 pm - 4:32 amBUF-STI
12h 07m1 stop
JetBlue Logo
12:12 pm - 8:18 pmSTI-BUF
9h 06m1 stop
$366JetBlue
Find Deal
Sun, Jan 25 - Wed, Jan 28
American Airlines Logo
6:05 am - 9:46 pmBUF-STI
14h 41m2 stops
American Airlines Logo
6:00 am - 9:06 pmSTI-BUF
16h 06m2 stops
$406American Airlines
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Sun, Jan 25 - Wed, Jan 28
JetBlue Logo
6:10 am - 2:16 pmBUF-STI
7h 06m1 stop
JetBlue Logo
12:12 pm - 8:18 pmSTI-BUF
9h 06m1 stop
$508JetBlue
Find Deal
Fri, Jan 2 - Thu, Jan 8
American Airlines Logo
7:15 pm - 2:24 pmBUF-STI
18h 09m2 stops
American Airlines Logo
6:00 am - 10:55 pmSTI-BUF
17h 55m2 stops
$657American Airlines
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Fri, Jan 2 - Thu, Jan 8
JetBlue Logo
11:04 am - 10:15 amBUF-STI
22h 11m2 stops
JetBlue Logo
12:12 pm - 8:18 pmSTI-BUF
9h 06m1 stop
$717JetBlue
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Wed, Dec 31 - Tue, Jan 6
American Airlines Logo
5:26 pm - 2:24 pmBUF-STI
19h 58m2 stops
American Airlines Logo
6:00 am - 10:55 pmSTI-BUF
17h 55m2 stops
$726American Airlines
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Wed, Dec 31 - Tue, Jan 6
JetBlue Logo
6:10 am - 8:32 pmBUF-STI
13h 22m1 stop
JetBlue Logo
12:12 pm - 8:18 pmSTI-BUF
9h 06m1 stop
$736JetBlue
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Wed, Dec 31 - Tue, Jan 6
United Airlines Logo
6:00 am - 2:53 pmBUF-STI
7h 53m1 stop
United Airlines Logo
4:00 pm - 10:55 pmSTI-BUF
7h 55m1 stop
$1,031United Airlines
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Tue, Dec 16 - Mon, Dec 22
JetBlue Logo
5:00 pm - 2:13 amBUF-STI
8h 13m1 stop
JetBlue Logo
11:25 am - 11:43 pmSTI-BUF
13h 18m1 stop
$1,216JetBlue
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Tue, Dec 16 - Mon, Dec 22

American Airlines flights from Buffalo to Santiago de los Caballeros

Our best American Airlines deals on Buffalo to Santiago de los Caballeros flight tickets
American Airlines
Jan 25
BUF6:05 amBuffalo
14h 41m
2 stops
STI9:46 pmSantiago de los Caballeros
Jan 28
STI6:00 amSantiago de los Caballeros
16h 06m
2 stops
BUF9:06 pmBuffalo
$406
Find similar
American Airlines
Jan 2
BUF7:15 pmBuffalo
18h 09m
2 stops
STI2:24 pmSantiago de los Caballeros
Jan 8
STI6:00 amSantiago de los Caballeros
17h 55m
2 stops
BUF10:55 pmBuffalo
$657
Find similar
American Airlines
Dec 31
BUF5:26 pmBuffalo
19h 58m
2 stops
STI2:24 pmSantiago de los Caballeros
Jan 6
STI6:00 amSantiago de los Caballeros
17h 55m
2 stops
BUF10:55 pmBuffalo
$726
Find similar

JetBlue flights from Buffalo to Santiago de los Caballeros

Our best JetBlue deals on Buffalo to Santiago de los Caballeros flight tickets
JetBlue
Jan 25
BUF3:25 pmBuffalo
12h 07m
1 stop
STI4:32 amSantiago de los Caballeros
Jan 28
STI12:12 pmSantiago de los Caballeros
9h 06m
1 stop
BUF8:18 pmBuffalo
$366
Find similar
JetBlue
Jan 2
BUF6:10 amBuffalo
7h 06m
1 stop
STI2:16 pmSantiago de los Caballeros
Jan 8
STI12:12 pmSantiago de los Caballeros
9h 06m
1 stop
BUF8:18 pmBuffalo
$508
Find similar
JetBlue
Dec 31
BUF11:04 amBuffalo
22h 11m
2 stops
STI10:15 amSantiago de los Caballeros
Jan 6
STI12:12 pmSantiago de los Caballeros
9h 06m
1 stop
BUF8:18 pmBuffalo
$717
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 1/25

11:51 am-12:50 am

1 stop11h 59m

Santiago de los Caballeros

Wed 1/28

6:38 am-2:58 pm

1 stop9h 20m

$360

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 1/25

3:25 pm-4:32 am

1 stop12h 07m

Santiago de los Caballeros

Wed 1/28

12:12 pm-8:18 pm

1 stop9h 06m

$366

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Sun 1/25

6:05 am-9:46 pm

2 stops14h 41m

Santiago de los Caballeros

Wed 1/28

6:00 am-9:06 pm

2 stops16h 06m

$406

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 1/2

6:10 am-2:16 pm

1 stop7h 06m

Santiago de los Caballeros

Thu 1/8

12:12 pm-8:18 pm

1 stop9h 06m

$508

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Fri 1/2

7:15 pm-2:24 pm

2 stops18h 09m

Santiago de los Caballeros

Thu 1/8

6:00 am-10:55 pm

2 stops17h 55m

$657

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Wed 12/31

11:04 am-10:15 am

2 stops22h 11m

Santiago de los Caballeros

Tue 1/6

12:12 pm-8:18 pm

1 stop9h 06m

$717

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Wed 12/31

5:26 pm-2:24 pm

2 stops19h 58m

Santiago de los Caballeros

Tue 1/6

6:00 am-10:55 pm

2 stops17h 55m

$726

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Wed 12/31

6:10 am-8:32 pm

1 stop13h 22m

Santiago de los Caballeros

Tue 1/6

12:12 pm-8:18 pm

1 stop9h 06m

$736

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Tue 12/16

6:00 am-2:53 pm

1 stop7h 53m

Santiago de los Caballeros

Mon 12/22

4:00 pm-10:55 pm

1 stop7h 55m

$1,031

BuffaloSantiago de los Caballeros

BUF - STI

BUFSTI

Buffalo

Tue 12/16

5:00 pm-2:13 am

1 stop8h 13m

Santiago de los Caballeros

Mon 12/22

11:25 am-11:43 pm

1 stop13h 18m

$1,216

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Buffalo to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Buffalo is in September. Flight prices, which tend to average around $443, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of September, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $452.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Buffalo to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $463. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Buffalo to Santiago de los Caballeros for around $1,251.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Buffalo to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $463. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $664 per ticket.

When to book flights from Buffalo to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santiago de los Caballeros (BUF to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santiago de los Caballeros

Fastest flight time

7h 53m

Direct flights

None
The fastest flight from Buffalo to Santiago de los Caballeros takes 7h 53m
There are no direct flights from Buffalo to Santiago de los Caballeros. There are no popular flight routes from Buffalo to Santiago de los Caballeros.
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  • How far is Buffalo to Santiago de los Caballeros by plane?

    A flight from Buffalo to Santiago de los Caballeros will travel around 1686.6 mi. In terms of flight time, this usually takes a little over 7h 06m.

  • When did momondo last update prices for flights from Buffalo Airport to Santiago de los Caballeros Airport?

    Prices for flights from Buffalo Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Buffalo Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santiago de los Caballeros?

Best airlines flying from Buffalo to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Buffalo to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $416Free CancellationRating
7.2
2,905 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from Buffalo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Buffalo to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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