Cheap flights from Buffalo to Chicago from $104

The month of February is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Buffalo averaging around $325.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $453. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Buffalo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $593.

Flying to Chicago O'Hare Intl Airport from Buffalo in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $462 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $692. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Buffalo to Chicago O'Hare Intl for the best Buffalo - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $365 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Buffalo for as low as $223 on momondo.

There are 4 cabin classes available to choose from on Buffalo to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 36% on your flight if you consider stops on a Buffalo to Chicago O'Hare Intl Airport flight.

As of November 2026, prices for Buffalo to Chicago O'Hare Intl Airport flights are approximately 125% more expensive when compared to flights at the same time last year.

As of November 2026, 31 flights take off from Buffalo and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 11:00AM, with 68% of daily flights taking off at noon.

As of November 2026, there are 217 flights per week flying from Buffalo to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Fri, with 15% of flights taking off on this day.