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You can purchase a ticket from Lille Lesquin to Brussels Bruxelles-National within the week and expect to pay $4 or more one-way.
The quickest bus available from Lille Lesquin will take 1h 40m to arrive in Brussels Bruxelles-National. The time it takes to travel between these two locations can vary by up to 0h 03m, depending on whether your bus has stops or different departure times. BlaBlaBus is one of the fastest options available.
Some of the buses offering service from Lille Lesquin to Brussels Bruxelles-National are FlixBus and BlaBlaBus. FlixBus has recently been found to be the cheapest option available at $8 round-trip.
While Brussels Bruxelles-National is 65.0 mi from Lille Lesquin, the distance by bus is longer and depends on the route taken. The bus takes 1h 40m, normally.