Known as "The Pearl of the Mississippi," Muscatine, Iowa, is a beloved destination. The Merrill Hotel is a AAA 4-star hotel, ranked the "No. 2 Hotel" in Iowa according to US News and World Report. Muscatine is a beloved destination, one where the pace is genteel, and the sunsets are unequaled—at least in the eyes of Mark Twain. Here, nestled along the banks of the Mississippi River. Within our doors, travelers will find sophisticated interiors, a curated art collection, and sumptuous accommodations designed with an eye towards luxury. Benefiting from a superb location on West Mississippi Drive near charming boutiques, dining, and museums, our hotel provides an inspired vantage point from which to wander. Discover complimentary Wi-Fi, cotton-rich linens, and stunning views in our guest rooms and suites, many of which overlook the Mississippi River. Dine at Maxwell's On The River, where new classic American food + drink are expertly crafted.