Cheap flights from Tampa to Guatemala City from $157

The cheapest month to fly to Guatemala City from Tampa is in January. Flight prices, which tend to average around $271, are often lower during this time because this is during the off-season. If you’re not able to fly to Guatemala City in January, then February is your next best option. Flight prices from Tampa to Guatemala City during February average around $304.

You are more likely to see cheaper flights to Guatemala City from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Guatemala City for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guatemala City from Tampa for as low as $332 on momondo.

You could potentially save up to 41% on your flight if you consider stops on a Tampa to Guatemala City flight.

As of August 2026, prices for Tampa to Guatemala City flights are approximately 19% more expensive when compared to flights at the same time last year.

United Airlines, Delta, and JetBlue are the most popular carriers operating from Tampa to Guatemala City La Aurora

Copa Airlines, American Airlines and Frontier are the top three most popular airlines that fly to Guatemala City from Tampa according to our data. Copa Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Guatemala City. Keep in mind that there are 7 different airlines that fly to Guatemala City on a routine basis, so you have a few additional options to choose from.

Houston (IAH) was the most common stop: 34% of momondo users choosing 1-stop flights on this route connected there.

Flights via Fort Lauderdale (FLL) offer the lowest average round-trip price of $370.

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 6h 00m.

Panama City (PTY) has the shortest average layover time for this route: 1h 17m.