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Cheap flights from St. Louis to Santo Domingo from $515

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Santo Domingo departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from St. Louis to Santo Domingo

Cheap round-trip flights

American Airlines Logo
5:02 pm - 11:35 amSTL-SDQ
16h 33m1 stop
American Airlines Logo
8:50 am - 9:48 pmSDQ-STL
14h 58m1 stop
$515American Airlines
Find Deal
mar., ene. 6 - mar., ene. 20
Delta Logo
6:00 am - 2:15 pmSTL-SDQ
6h 15m1 stop
Delta Logo
7:05 am - 8:39 pmSDQ-STL
15h 34m2 stops
$519Delta
Find Deal
mié., ene. 21 - mar., ene. 27
American Airlines Logo
5:28 am - 3:20 pmSTL-SDQ
8h 52m1 stop
American Airlines Logo
4:20 pm - 11:59 pmSDQ-STL
8h 39m1 stop
$525American Airlines
Find Deal
vie., sep. 5 - lun., sep. 8
American Airlines Logo
5:28 am - 3:20 pmSTL-SDQ
8h 52m1 stop
American Airlines Logo
12:15 pm - 11:48 pmSDQ-STL
12h 33m2 stops
$529American Airlines
Find Deal
vie., sep. 5 - lun., sep. 8
Frontier Logo
2:36 pm - 12:32 amSTL-SDQ
8h 56m1 stop
Frontier Logo
1:22 pm - 11:47 pmSDQ-STL
11h 25m2 stops
$597Frontier
Find Deal
jue., ago. 14 - lun., ago. 18
Delta Logo
6:00 am - 2:20 pmSTL-SDQ
6h 20m1 stop
Delta Logo
3:40 pm - 8:39 pmSDQ-STL
6h 59m1 stop
$870Delta
Find Deal
lun., dic. 29 - lun., ene. 12
Frontier Logo
3:40 pm - 10:11 amSTL-SDQ
16h 31m1 stop
Frontier Logo
7:55 pm - 10:46 pmSDQ-STL
28h 51m1 stop
$928Frontier
Find Deal
dom., dic. 28 - dom., ene. 4
United Airlines Logo
9:17 am - 1:50 amSTL-SDQ
15h 33m2 stops
United Airlines Logo
3:20 pm - 11:44 pmSDQ-STL
9h 24m1 stop
$1,009United Airlines
Find Deal
jue., ago. 28 - dom., ago. 31
United Airlines Logo
5:20 pm - 1:50 amSTL-SDQ
7h 30m1 stop
United Airlines Logo
3:20 pm - 11:44 pmSDQ-STL
9h 24m1 stop
$1,099United Airlines
Find Deal
jue., ago. 14 - lun., ago. 18
Spirit Airlines Logo
12:20 pm - 3:06 amSTL-SDQ
12h 46m1 stop
Spirit Airlines Logo
4:44 am - 11:01 amSDQ-STL
8h 17m1 stop
$1,403Spirit Airlines
Find Deal
dom., dic. 28 - sáb., ene. 3

United Airlines flights from St. Louis to Santo Domingo

Our best United Airlines deals on St. Louis to Santo Domingo flight tickets
United Airlines
Aug 28
STL9:17 amLambert-St Louis
15h 33m
2 stops
SDQ1:50 amSanto Domingo Las Americas
Aug 31
SDQ3:20 pmSanto Domingo Las Americas
9h 24m
1 stop
STL11:44 pmLambert-St Louis
$1,009
Find similar
United Airlines
Aug 14
STL5:20 pmLambert-St Louis
7h 30m
1 stop
SDQ1:50 amSanto Domingo Las Americas
Aug 18
SDQ3:20 pmSanto Domingo Las Americas
9h 24m
1 stop
STL11:44 pmLambert-St Louis
$1,099
Find similar
United Airlines
Aug 28
STL5:22 pmLambert-St Louis
7h 28m
1 stop
SDQ1:50 amSanto Domingo Las Americas
Aug 31
SDQ3:20 pmSanto Domingo Las Americas
9h 24m
1 stop
STL11:44 pmLambert-St Louis
$1,165
Find similar

American Airlines flights from St. Louis to Santo Domingo

Our best American Airlines deals on St. Louis to Santo Domingo flight tickets
American Airlines
Jan 6
STL5:02 pmLambert-St Louis
16h 33m
1 stop
SDQ11:35 amSanto Domingo Las Americas
Jan 20
SDQ8:50 amSanto Domingo Las Americas
14h 58m
1 stop
STL9:48 pmLambert-St Louis
$515
Find similar
American Airlines
Sep 5
STL5:28 amLambert-St Louis
8h 52m
1 stop
SDQ3:20 pmSanto Domingo Las Americas
Sep 8
SDQ4:20 pmSanto Domingo Las Americas
8h 39m
1 stop
STL11:59 pmLambert-St Louis
$525
Find similar
American Airlines
Sep 5
STL5:28 amLambert-St Louis
8h 52m
1 stop
SDQ3:20 pmSanto Domingo Las Americas
Sep 8
SDQ12:15 pmSanto Domingo Las Americas
12h 33m
2 stops
STL11:48 pmLambert-St Louis
$529
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 4, 2025.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

mar. 1/6

5:02 pm-11:35 am

1 stop16h 33m

Santo Domingo Las Americas

mar. 1/20

8:50 am-9:48 pm

1 stop14h 58m

$515

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

mié. 1/21

6:00 am-2:15 pm

1 stop6h 15m

Santo Domingo Las Americas

mar. 1/27

7:05 am-8:39 pm

2 stops15h 34m

$519

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

vie. 9/5

5:28 am-3:20 pm

1 stop8h 52m

Santo Domingo Las Americas

lun. 9/8

4:20 pm-11:59 pm

1 stop8h 39m

$525

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

vie. 9/5

5:28 am-3:20 pm

1 stop8h 52m

Santo Domingo Las Americas

lun. 9/8

12:15 pm-11:48 pm

2 stops12h 33m

$529

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

jue. 8/14

2:36 pm-12:32 am

1 stop8h 56m

Santo Domingo Las Americas

lun. 8/18

1:22 pm-11:47 pm

2 stops11h 25m

$597

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

lun. 12/29

6:00 am-2:20 pm

1 stop6h 20m

Santo Domingo Las Americas

lun. 1/12

3:40 pm-8:39 pm

1 stop6h 59m

$870

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

dom. 12/28

3:40 pm-10:11 am

1 stop16h 31m

Santo Domingo Las Americas

dom. 1/4

7:55 pm-10:46 pm

1 stop28h 51m

$928

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

jue. 8/28

9:17 am-1:50 am

2 stops15h 33m

Santo Domingo Las Americas

dom. 8/31

3:20 pm-11:44 pm

1 stop9h 24m

$1,009

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

jue. 8/14

5:20 pm-1:50 am

1 stop7h 30m

Santo Domingo Las Americas

lun. 8/18

3:20 pm-11:44 pm

1 stop9h 24m

$1,099

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

dom. 12/28

12:20 pm-3:06 am

1 stop12h 46m

Santo Domingo Las Americas

sáb. 1/3

4:44 am-11:01 am

1 stop8h 17m

$1,403

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from St. Louis to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until March to fly from St. Louis, when ticket prices are also cheap, with an average price of $534.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $486. The most expensive day to fly to Santo Domingo is Friday, with ticket prices averaging around $765.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $445. Try not to purchase tickets in the morning because they tend to be around $610. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from St. Louis to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santo Domingo (STL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santo Domingo

Best Price Found

$515

Fastest flight time

6h 15m

Direct flights

None

Airports in Santo Domingo

1 airport
The best flight deal from St. Louis to Santo Domingo found on momondo in the last 72 hours is $515
The fastest flight from St. Louis to Santo Domingo takes 6h 15m
There are no direct flights from St. Louis to Santo Domingo. Popular non-direct route for this connection is Lambert-St Louis Airport - Santo Domingo Las Americas Airport.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
Search flight deals

  • How far is Lambert-St Louis to Santo Domingo Las Americas by plane?

    The straight-line distance from Lambert-St Louis to Santo Domingo Las Americas is 1847.1 mi. A reasonable flight in good conditions will take 6h 15m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from St. Louis to Santo Domingo?

Best airlines flying from St. Louis to Santo Domingo

Compare and see reviews for airlines that fly from St. Louis to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $371Free CancellationRating
5.8
3,232 reviews
Search Frontier flights
DeltaPriceFrom $423Free CancellationRating
8.0
7,987 reviews
Search Delta flights
American AirlinesPriceFrom $462Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Why should I use momondo to find a flight deal from St. Louis to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from St. Louis to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from St. Louis to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from St. Louis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from St. Louis to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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