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Cheap flights from St. Louis to Santo Domingo from $214

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Santo Domingo departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 10:46 pm
STL
-
SDQ
14h 46m
1 stop
United Airlines Logo
3:20 pm - 11:38 pm
SDQ
-
STL
9h 18m
1 stop
$600United Airlines
Tue, Sep 15 - Tue, Sep 22
American Airlines Logo
5:15 am - 5:29 pm
STL
-
SDQ
10h 14m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
SDQ
-
STL
10h 49m
1 stop
$600American Airlines
Fri, Jan 29 - Wed, Feb 3
American Airlines Logo
6:00 am - 5:29 pm
STL
-
SDQ
9h 29m
2 stops
American Airlines Logo
3:10 pm - 11:58 pm
SDQ
-
STL
10h 48m
2 stops
$605American Airlines
Fri, Jan 29 - Wed, Feb 3
American Airlines Logo
8:13 am - 10:26 pm
STL
-
SDQ
12h 13m
2 stops
American Airlines Logo
3:00 pm - 10:44 pm
SDQ
-
STL
9h 44m
1 stop
$605American Airlines
Fri, Jan 29 - Wed, Feb 3
Delta Logo
7:05 am - 2:40 pm
STL
-
SDQ
5h 35m
1 stop
Delta Logo
7:30 am - 8:37 pm
SDQ
-
STL
15h 07m
2 stops
$705Delta
Sat, Nov 28 - Sat, Feb 6
Delta Logo
7:05 am - 2:40 pm
STL
-
SDQ
5h 35m
1 stop
Delta Logo
3:40 pm - 8:49 pm
SDQ
-
STL
7h 09m
1 stop
$740Delta
Sat, Nov 28 - Sat, Feb 6
Delta Logo
6:00 am - 1:28 pm
STL
-
SDQ
6h 28m
1 stop
Delta Logo
2:53 pm - 11:42 pm
SDQ
-
STL
9h 49m
1 stop
$750Delta
Wed, Aug 19 - Tue, Sep 15
United Airlines Logo
6:00 am - 10:46 pm
STL
-
SDQ
15h 46m
1 stop
United Airlines Logo
5:00 am - 9:56 pm
SDQ
-
STL
17h 56m
1 stop
$820United Airlines
Mon, Oct 26 - Fri, Oct 30
United Airlines Logo
7:30 am - 10:46 pm
STL
-
SDQ
14h 16m
2 stops
United Airlines Logo
3:18 pm - 9:03 am
SDQ
-
STL
18h 45m
1 stop
$825United Airlines
Mon, Oct 26 - Fri, Oct 30
United Airlines Logo
7:30 am - 10:46 pm
STL
-
SDQ
14h 16m
2 stops
United Airlines Logo
5:00 am - 4:51 pm
SDQ
-
STL
12h 51m
2 stops
$825United Airlines
Mon, Oct 26 - Fri, Oct 30

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American Airlines flights from St. Louis to Santo Domingo

Our best American Airlines deals on St. Louis to Santo Domingo flight tickets
American Airlines
Sep 15
STL6:00 amLambert-St Louis
11h 34m
2 stops
SDQ6:34 pmSanto Domingo Las Americas
Sep 22
SDQ2:15 pmSanto Domingo Las Americas
8h 34m
1 stop
STL9:49 pmLambert-St Louis
$605
American Airlines
Aug 27
STL5:42 pmLambert-St Louis
18h 18m
1 stop
SDQ1:00 pmSanto Domingo Las Americas
Sep 10
SDQ2:15 pmSanto Domingo Las Americas
10h 44m
1 stop
STL11:59 pmLambert-St Louis
$620
American Airlines
Aug 27
STL3:25 pmLambert-St Louis
17h 00m
2 stops
SDQ9:25 amSanto Domingo Las Americas
Sep 10
SDQ4:20 pmSanto Domingo Las Americas
8h 39m
1 stop
STL11:59 pmLambert-St Louis
$625

Delta flights from St. Louis to Santo Domingo

Our best Delta deals on St. Louis to Santo Domingo flight tickets
Delta
Nov 28
STL7:05 amLambert-St Louis
5h 35m
1 stop
SDQ2:40 pmSanto Domingo Las Americas
Feb 6
SDQ7:30 amSanto Domingo Las Americas
15h 07m
2 stops
STL8:37 pmLambert-St Louis
$705
Delta
Nov 28
STL7:05 amLambert-St Louis
5h 35m
1 stop
SDQ2:40 pmSanto Domingo Las Americas
Feb 6
SDQ3:40 pmSanto Domingo Las Americas
7h 09m
1 stop
STL8:49 pmLambert-St Louis
$740
Delta
Aug 18
STL6:00 amLambert-St Louis
6h 28m
1 stop
SDQ1:28 pmSanto Domingo Las Americas
Sep 17
SDQ2:53 pmSanto Domingo Las Americas
9h 49m
1 stop
STL11:42 pmLambert-St Louis
$750

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 9/15

7:00 am-10:46 pm

1 stop14h 46m

Santo Domingo Las Americas

Tue 9/22

3:20 pm-11:38 pm

1 stop9h 18m

$600

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 1/29

5:15 am-5:29 pm

1 stop10h 14m

Santo Domingo Las Americas

Wed 2/3

3:10 pm-11:59 pm

1 stop10h 49m

$600

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 1/29

6:00 am-5:29 pm

2 stops9h 29m

Santo Domingo Las Americas

Wed 2/3

3:10 pm-11:58 pm

2 stops10h 48m

$605

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 1/29

8:13 am-10:26 pm

2 stops12h 13m

Santo Domingo Las Americas

Wed 2/3

3:00 pm-10:44 pm

1 stop9h 44m

$605

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sat 11/28

7:05 am-2:40 pm

1 stop5h 35m

Santo Domingo Las Americas

Sat 2/6

7:30 am-8:37 pm

2 stops15h 07m

$705
Quickest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sat 11/28

7:05 am-2:40 pm

1 stop5h 35m

Santo Domingo Las Americas

Sat 2/6

3:40 pm-8:49 pm

1 stop7h 09m

$740

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 8/19

6:00 am-1:28 pm

1 stop6h 28m

Santo Domingo Las Americas

Tue 9/15

2:53 pm-11:42 pm

1 stop9h 49m

$750

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 10/26

6:00 am-10:46 pm

1 stop15h 46m

Santo Domingo Las Americas

Fri 10/30

5:00 am-9:56 pm

1 stop17h 56m

$820

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 10/26

7:30 am-10:46 pm

2 stops14h 16m

Santo Domingo Las Americas

Fri 10/30

3:18 pm-9:03 am

1 stop18h 45m

$825

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 10/26

7:30 am-10:46 pm

2 stops14h 16m

Santo Domingo Las Americas

Fri 10/30

5:00 am-4:51 pm

2 stops12h 51m

$825

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from St. Louis to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from $600 to $670.
The lowest price recently found on this route was $600.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until February to fly from St. Louis, when ticket prices are also cheap, with an average price of $580.

Can stopping save me money on St. Louis to Santo Domingo flights?

You could potentially save up to 5% on your flight if you consider stops on a St. Louis to Santo Domingo flight.

When to book flights from St. Louis to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santo Domingo (STL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santo Domingo

Fastest flight time

13h 26m

Direct flights

None
The fastest flight from St. Louis to Santo Domingo takes 13h 26m
There are no direct flights from St. Louis to Santo Domingo. There are no popular flight routes from St. Louis to Santo Domingo.
Search flight deals

Frequently asked questions about flying from St. Louis to Santo Domingo

  • How far is Lambert-St Louis to Santo Domingo Las Americas by plane?

    The straight-line distance from Lambert-St Louis to Santo Domingo Las Americas is 1847.1 mi. A reasonable flight in good conditions will take 13h 26m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from St. Louis to Santo Domingo?

Best airlines flying from St. Louis to Santo Domingo

Compare and see reviews for airlines that fly from St. Louis to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $524Free CancellationRating
7.8
8,483 reviews
Search Delta flights
American AirlinesPriceFrom $529Free CancellationRating
7.1
11,845 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from St. Louis to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from St. Louis to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from St. Louis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from St. Louis to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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