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Cheap flights from St. Louis to Santo Domingo from $247

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Santo Domingo departing on 7/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:08 pm - 10:53 am
STL
-
SDQ
13h 45m
2 stops
Frontier Logo
12:18 pm - 8:57 am
SDQ
-
STL
45h 39m
2 stops
$545Frontier
Wed, Jul 15 - Wed, Jul 22
Frontier Logo
3:41 pm - 11:03 am
STL
-
SDQ
18h 22m
2 stops
Frontier Logo
12:18 pm - 8:57 am
SDQ
-
STL
45h 39m
2 stops
$554Frontier
Thu, Jul 9 - Wed, Jul 15
American Airlines Logo
6:43 am - 9:25 pm
STL
-
SDQ
13h 42m
2 stops
American Airlines Logo
7:40 pm - 10:24 am
SDQ
-
STL
15h 44m
1 stop
$595American Airlines
Wed, Jul 15 - Wed, Jul 22
Frontier Logo
8:08 pm - 11:06 am
STL
-
SDQ
13h 58m
2 stops
Frontier Logo
12:21 pm - 12:14 am
SDQ
-
STL
12h 53m
2 stops
$609Frontier
Fri, Sep 4 - Tue, Sep 8
American Airlines Logo
5:48 pm - 12:57 pm
STL
-
SDQ
18h 09m
1 stop
American Airlines Logo
1:57 pm - 11:32 pm
SDQ
-
STL
10h 35m
1 stop
$610American Airlines
Mon, Jul 6 - Mon, Jul 13
American Airlines Logo
6:13 pm - 9:27 am
STL
-
SDQ
14h 14m
2 stops
American Airlines Logo
1:57 pm - 11:32 pm
SDQ
-
STL
10h 35m
1 stop
$615American Airlines
Mon, Jul 6 - Mon, Jul 13
Frontier Logo
3:41 pm - 11:03 am
STL
-
SDQ
18h 22m
2 stops
Frontier Logo
12:18 pm - 8:57 am
SDQ
-
STL
45h 39m
2 stops
$622Frontier
Sun, Aug 9 - Sat, Aug 15
Frontier Logo
3:33 pm - 11:06 am
STL
-
SDQ
42h 33m
2 stops
Frontier Logo
12:21 pm - 9:40 am
SDQ
-
STL
22h 19m
2 stops
$625Frontier
Fri, Sep 4 - Tue, Sep 8
American Airlines Logo
5:00 am - 1:22 pm
STL
-
SDQ
7h 22m
1 stop
American Airlines Logo
2:22 pm - 10:40 pm
SDQ
-
STL
9h 18m
1 stop
$640American Airlines
Fri, Sep 4 - Tue, Sep 8
American Airlines Logo
5:00 am - 1:22 pm
STL
-
SDQ
7h 22m
1 stop
American Airlines Logo
4:24 pm - 10:20 am
SDQ
-
STL
18h 56m
2 stops
$645American Airlines
Fri, Sep 4 - Tue, Sep 8

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American Airlines flights from St. Louis to Santo Domingo

Our best American Airlines deals on St. Louis to Santo Domingo flight tickets
American Airlines
Jul 15
STL6:43 amLambert-St Louis
13h 42m
2 stops
SDQ9:25 pmSanto Domingo Las Americas
Jul 22
SDQ7:40 pmSanto Domingo Las Americas
15h 44m
1 stop
STL10:24 amLambert-St Louis
$595
American Airlines
Sep 4
STL5:00 amLambert-St Louis
7h 22m
1 stop
SDQ1:22 pmSanto Domingo Las Americas
Sep 8
SDQ2:22 pmSanto Domingo Las Americas
9h 18m
1 stop
STL10:40 pmLambert-St Louis
$640
American Airlines
Sep 4
STL5:00 amLambert-St Louis
7h 22m
1 stop
SDQ1:22 pmSanto Domingo Las Americas
Sep 8
SDQ4:24 pmSanto Domingo Las Americas
18h 56m
2 stops
STL10:20 amLambert-St Louis
$645

United Airlines flights from St. Louis to Santo Domingo

Our best United Airlines deals on St. Louis to Santo Domingo flight tickets
United Airlines
Jul 15
STL6:01 amLambert-St Louis
15h 45m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
Jul 22
SDQ3:20 pmSanto Domingo Las Americas
9h 24m
1 stop
STL11:44 pmLambert-St Louis
$661
United Airlines
Jul 13
STL5:59 pmLambert-St Louis
27h 47m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
Jul 17
SDQ6:00 amSanto Domingo Las Americas
31h 11m
3 stops
STL12:11 pmLambert-St Louis
$795
United Airlines
Oct 11
STL9:04 amLambert-St Louis
12h 42m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
Oct 16
SDQ6:00 amSanto Domingo Las Americas
16h 21m
2 stops
STL9:21 pmLambert-St Louis
$835

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 7/15

8:08 pm-10:53 am

2 stops13h 45m

Santo Domingo Las Americas

Wed 7/22

12:18 pm-8:57 am

2 stops45h 39m

$545

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Thu 7/9

3:41 pm-11:03 am

2 stops18h 22m

Santo Domingo Las Americas

Wed 7/15

12:18 pm-8:57 am

2 stops45h 39m

$554

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 7/15

6:43 am-9:25 pm

2 stops13h 42m

Santo Domingo Las Americas

Wed 7/22

7:40 pm-10:24 am

1 stop15h 44m

$595

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 9/4

8:08 pm-11:06 am

2 stops13h 58m

Santo Domingo Las Americas

Tue 9/8

12:21 pm-12:14 am

2 stops12h 53m

$609

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 7/6

5:48 pm-12:57 pm

1 stop18h 09m

Santo Domingo Las Americas

Mon 7/13

1:57 pm-11:32 pm

1 stop10h 35m

$610

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 7/6

6:13 pm-9:27 am

2 stops14h 14m

Santo Domingo Las Americas

Mon 7/13

1:57 pm-11:32 pm

1 stop10h 35m

$615

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sun 8/9

3:41 pm-11:03 am

2 stops18h 22m

Santo Domingo Las Americas

Sat 8/15

12:18 pm-8:57 am

2 stops45h 39m

$622

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 9/4

3:33 pm-11:06 am

2 stops42h 33m

Santo Domingo Las Americas

Tue 9/8

12:21 pm-9:40 am

2 stops22h 19m

$625
Quickest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 9/4

5:00 am-1:22 pm

1 stop7h 22m

Santo Domingo Las Americas

Tue 9/8

2:22 pm-10:40 pm

1 stop9h 18m

$640

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 9/4

5:00 am-1:22 pm

1 stop7h 22m

Santo Domingo Las Americas

Tue 9/8

4:24 pm-10:20 am

2 stops18h 56m

$645

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from St. Louis to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until February to fly from St. Louis, when ticket prices are also cheap, with an average price of $580.

Can stopping save me money on St. Louis to Santo Domingo flights?

You could potentially save up to 5% on your flight if you consider stops on a St. Louis to Santo Domingo flight.

When to book flights from St. Louis to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santo Domingo (STL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santo Domingo

Fastest flight time

6h 28m

Direct flights

None
The fastest flight from St. Louis to Santo Domingo takes 6h 28m
There are no direct flights from St. Louis to Santo Domingo. There are no popular flight routes from St. Louis to Santo Domingo.
Search flight deals

Frequently asked questions about flying from St. Louis to Santo Domingo

  • How far is Lambert-St Louis to Santo Domingo Las Americas by plane?

    The straight-line distance from Lambert-St Louis to Santo Domingo Las Americas is 1847.1 mi. A reasonable flight in good conditions will take 6h 28m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from St. Louis to Santo Domingo?

Best airlines flying from St. Louis to Santo Domingo

Compare and see reviews for airlines that fly from St. Louis to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $524Free CancellationRating
7.9
8,403 reviews
Search Delta flights
American AirlinesPriceFrom $529Free CancellationRating
7.1
11,654 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Why should I use momondo to find a flight deal from St. Louis to Santo Domingo?

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Can I find flights from St. Louis to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from St. Louis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from St. Louis to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

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