Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Santiago de los Caballeros from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Santiago de los Caballeros departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:05 am - 5:33 pmCHS  Charleston-STI Santiago de los Caballeros
11h 28m1 stop New York John F Kennedy Intl
Delta Logo
7:05 pm - 12:12 pmSTI  Santiago de los Caballeros-CHS Charleston
17h 07m1 stop New York John F Kennedy Intl
$364Delta
Tue, Oct 27 - Fri, Oct 30
Delta Logo
6:05 am - 5:33 pmCHS  Charleston-STI Santiago de los Caballeros
11h 28m1 stop New York John F Kennedy Intl
Delta Logo
7:05 pm - 12:12 pmSTI  Santiago de los Caballeros-CHS Charleston
17h 07m1 stop New York John F Kennedy Intl
$364Delta
Wed, Oct 28 - Fri, Oct 30
American Airlines Logo
7:00 am - 2:15 pmCHS  Charleston-STI Santiago de los Caballeros
7h 15m1 stop Miami
American Airlines Logo
3:15 pm - 9:47 amSTI  Santiago de los Caballeros-CHS Charleston
18h 32m2 stops Miami Charlotte Douglas
$410American Airlines
Wed, Sep 23 - Wed, Sep 30
American Airlines Logo
7:41 pm - 2:15 pmCHS  Charleston-STI Santiago de los Caballeros
18h 34m2 stops Charlotte Douglas Miami
American Airlines Logo
3:15 pm - 9:47 amSTI  Santiago de los Caballeros-CHS Charleston
18h 32m2 stops Miami Charlotte Douglas
$410American Airlines
Wed, Sep 23 - Wed, Sep 30
JetBlue Logo
6:50 am - 2:45 pmCLT  Charlotte Douglas-STI Santiago de los Caballeros
7h 55m1 stop Fort Lauderdale
JetBlue Logo
3:55 pm - 11:05 pmSTI  Santiago de los Caballeros-CLT Charlotte Douglas
7h 10m1 stop Fort Lauderdale
$495JetBlue
Sat, Oct 10 - Sun, Oct 18
JetBlue Logo
9:00 am - 3:33 pmCLT  Charlotte Douglas-STI Santiago de los Caballeros
5h 33m1 stop Fort Lauderdale
JetBlue Logo
4:43 pm - 11:05 pmSTI  Santiago de los Caballeros-CLT Charlotte Douglas
7h 22m1 stop Fort Lauderdale
$498JetBlue
Mon, Nov 9 - Thu, Nov 12
Multiple Airlines Logo
7:30 am - 1:27 pmCLT  Charlotte Douglas-STI Santiago de los Caballeros
5h 57m1 stop Fort Lauderdale
Multiple Airlines Logo
1:43 pm - 4:38 pmSTI  Santiago de los Caballeros-CLT Charlotte Douglas
26h 55m1 stop Philadelphia
$509Multiple Airlines
Sun, Sep 13 - Sat, Oct 10
United Airlines Logo
9:54 am - 10:52 pmCLT  Charlotte Douglas-STI Santiago de los Caballeros
12h 58m1 stop Newark
United Airlines Logo
6:00 am - 4:35 pmSTI  Santiago de los Caballeros-CLT Charlotte Douglas
10h 35m1 stop Newark
$618United Airlines
Wed, Sep 23 - Wed, Sep 30
United Airlines Logo
8:29 pm - 12:57 pmGSP  Greenville-STI Santiago de los Caballeros
16h 28m1 stop Newark
United Airlines Logo
2:07 pm - 11:15 pmSTI  Santiago de los Caballeros-GSP Greenville
9h 08m1 stop Newark
$625United Airlines
Mon, Sep 14 - Mon, Sep 21
Multiple Airlines Logo
8:55 am - 12:55 pmCLT  Charlotte Douglas-STI Santiago de los Caballeros
51h 00m2 stops Toronto Pearson Intl Providenciales
Multiple Airlines Logo
1:30 pm - 4:26 pmSTI  Santiago de los Caballeros-CLT Charlotte Douglas
51h 56m2 stops Providenciales Toronto Pearson Intl
$1,614Multiple Airlines
Tue, Dec 22 - Mon, Jan 4

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from South Carolina to Santiago de los Caballeros

Our best American Airlines deals on South Carolina to Santiago de los Caballeros flight tickets
American Airlines
Sep 23
CHS7:41 pmCharleston
18h 34m
2 stops
STI2:15 pmSantiago de los Caballeros
Sep 30
STI3:15 pmSantiago de los Caballeros
18h 32m
2 stops
CHS9:47 amCharleston
$410
American Airlines
Oct 14
CHS7:04 pmCharleston
19h 08m
2 stops
STI2:12 pmSantiago de los Caballeros
Oct 17
STI3:12 pmSantiago de los Caballeros
17h 22m
2 stops
CHS8:34 amCharleston
$415
American Airlines
Sep 30
CHS5:22 pmCharleston
20h 53m
2 stops
STI2:15 pmSantiago de los Caballeros
Oct 3
STI3:15 pmSantiago de los Caballeros
21h 34m
2 stops
CHS12:49 pmCharleston
$522

Delta flights from South Carolina to Santiago de los Caballeros

Our best Delta deals on South Carolina to Santiago de los Caballeros flight tickets
Delta
Oct 27
CHS6:05 amCharleston
11h 28m
1 stop
STI5:33 pmSantiago de los Caballeros
Oct 30
STI7:05 pmSantiago de los Caballeros
17h 07m
1 stop
CHS12:12 pmCharleston
$364
Delta
Oct 27
CHS6:05 amCharleston
11h 28m
1 stop
STI5:33 pmSantiago de los Caballeros
Oct 30
STI7:05 pmSantiago de los Caballeros
18h 13m
2 stops
CHS1:18 pmCharleston
$369
Delta
Sep 30
CHS6:00 amCharleston
11h 59m
1 stop
STI5:59 pmSantiago de los Caballeros
Oct 3
STI7:30 pmSantiago de los Caballeros
16h 41m
1 stop
CHS12:11 pmCharleston
$401

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSantiago de los Caballeros

CHS Charleston - STI Santiago de los Caballeros

CHSSTI

Charleston

Tue 10/27

6:05 am-5:33 pm

1 stop11h 28m

Santiago de los Caballeros

Fri 10/30

7:05 pm-12:12 pm

1 stop17h 07m

$364

CharlestonSantiago de los Caballeros

CHS Charleston - STI Santiago de los Caballeros

CHSSTI

Charleston

Wed 10/28

6:05 am-5:33 pm

1 stop11h 28m

Santiago de los Caballeros

Fri 10/30

7:05 pm-12:12 pm

1 stop17h 07m

$364

CharlestonSantiago de los Caballeros

CHS Charleston - STI Santiago de los Caballeros

CHSSTI

Charleston

Wed 9/23

7:00 am-2:15 pm

1 stop7h 15m

Santiago de los Caballeros

Wed 9/30

3:15 pm-9:47 am

2 stops18h 32m

$410

CharlestonSantiago de los Caballeros

CHS Charleston - STI Santiago de los Caballeros

CHSSTI

Charleston

Wed 9/23

7:41 pm-2:15 pm

2 stops18h 34m

Santiago de los Caballeros

Wed 9/30

3:15 pm-9:47 am

2 stops18h 32m

$410

CharlotteSantiago de los Caballeros

CLT Charlotte Douglas - STI Santiago de los Caballeros

CLTSTI

Charlotte Douglas

Sat 10/10

6:50 am-2:45 pm

1 stop7h 55m

Santiago de los Caballeros

Sun 10/18

3:55 pm-11:05 pm

1 stop7h 10m

$495
Quickest round-trip

CharlotteSantiago de los Caballeros

CLT Charlotte Douglas - STI Santiago de los Caballeros

CLTSTI

Charlotte Douglas

Mon 11/9

9:00 am-3:33 pm

1 stop5h 33m

Santiago de los Caballeros

Thu 11/12

4:43 pm-11:05 pm

1 stop7h 22m

$498

CharlotteSantiago de los Caballeros

CLT Charlotte Douglas - STI Santiago de los Caballeros

CLTSTI

Charlotte Douglas

Sun 9/13

7:30 am-1:27 pm

1 stop5h 57m

Santiago de los Caballeros

Sat 10/10

1:43 pm-4:38 pm

1 stop26h 55m

$509

CharlotteSantiago de los Caballeros

CLT Charlotte Douglas - STI Santiago de los Caballeros

CLTSTI

Charlotte Douglas

Wed 9/23

9:54 am-10:52 pm

1 stop12h 58m

Santiago de los Caballeros

Wed 9/30

6:00 am-4:35 pm

1 stop10h 35m

$618

GreenvilleSantiago de los Caballeros

GSP Greenville - STI Santiago de los Caballeros

GSPSTI

Greenville

Mon 9/14

8:29 pm-12:57 pm

1 stop16h 28m

Santiago de los Caballeros

Mon 9/21

2:07 pm-11:15 pm

1 stop9h 08m

$625

CharlotteSantiago de los Caballeros

CLT Charlotte Douglas - STI Santiago de los Caballeros

CLTSTI

Charlotte Douglas

Tue 12/22

8:55 am-12:55 pm

2 stops51h 00m

Santiago de los Caballeros

Mon 1/4

1:30 pm-4:26 pm

2 stops51h 56m

$1,614

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from South Carolina to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Santiago de los Caballeros flights?

You could potentially save up to 19% on your flight if you consider stops on a South Carolina to Santiago de los Caballeros flight.

Cheap South Carolina to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santiago de los Caballeros

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from South Carolina to Santiago de los Caballeros takes 5h 33m
There are no direct flights from South Carolina to Santiago de los Caballeros. There are no popular flight routes from South Carolina to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from South Carolina to Santiago de los Caballeros

  • When did momondo last update prices for flights from South Carolina to Santiago de los Caballeros Airport?

    Prices for flights from South Carolina to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from South Carolina to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santiago de los Caballeros

Compare and see reviews for airlines that fly from South Carolina to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.1
11,898 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Santiago de los Caballeros for you.

Can I find flights from South Carolina to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Santiago de los Caballeros?

momondo helps you find the best flight between South Carolina and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santiago de los Caballeros trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 9/9
Wed 9/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Dominican Republic