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Cheap flights from South Carolina to Santiago de los Caballeros from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Santiago de los Caballeros departing on 3/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:55 am - 3:35 pm
CLT
-
STI
8h 40m
1 stop
Spirit Airlines Logo
3:41 pm - 11:56 pm
STI
-
CLT
8h 15m
1 stop
$256Spirit Airlines
Tue, Mar 3 - Tue, Mar 10
Spirit Airlines Logo
1:20 pm - 1:49 am
CLT
-
STI
12h 29m
1 stop
Spirit Airlines Logo
3:43 pm - 12:38 am
STI
-
CLT
8h 55m
1 stop
$263Spirit Airlines
Tue, Mar 17 - Tue, Mar 24
Spirit Airlines Logo
6:00 am - 2:35 pm
CLT
-
STI
8h 35m
1 stop
Spirit Airlines Logo
3:28 pm - 12:38 am
STI
-
CLT
9h 10m
1 stop
$269Spirit Airlines
Mon, Mar 23 - Tue, Mar 31
Spirit Airlines Logo
1:20 pm - 1:49 am
CLT
-
STI
12h 29m
1 stop
Spirit Airlines Logo
3:43 pm - 12:38 am
STI
-
CLT
8h 55m
1 stop
$273Spirit Airlines
Mon, Mar 16 - Mon, Mar 23
Spirit Airlines Logo
6:00 am - 2:35 pm
CLT
-
STI
8h 35m
1 stop
Spirit Airlines Logo
2:46 am - 8:21 am
STI
-
CLT
5h 35m
1 stop
$283Spirit Airlines
Thu, Mar 19 - Wed, Mar 25
Multiple Airlines Logo
6:37 pm - 3:35 pm
CLT
-
STI
19h 58m
1 stop
Multiple Airlines Logo
4:40 pm - 1:54 pm
STI
-
CLT
22h 14m
1 stop
$298Multiple Airlines
Fri, Feb 20 - Wed, Feb 25
Multiple Airlines Logo
11:00 am - 3:35 pm
CLT
-
STI
27h 35m
1 stop
Multiple Airlines Logo
4:40 pm - 1:54 pm
STI
-
CLT
22h 14m
1 stop
$301Multiple Airlines
Thu, Feb 19 - Wed, Feb 25
American Airlines Logo
6:00 am - 12:30 pm
CHS
-
STI
6h 30m
1 stop
American Airlines Logo
7:00 am - 11:55 pm
STI
-
CHS
16h 55m
2 stops
$319American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
8:13 pm - 9:30 pm
CHS
-
STI
24h 17m
1 stop
American Airlines Logo
1:30 pm - 11:59 pm
STI
-
CHS
10h 29m
1 stop
$322American Airlines
Thu, Mar 5 - Thu, Mar 12
Delta Logo
7:45 am - 12:30 am
GSP
-
STI
16h 45m
2 stops
Delta Logo
8:50 pm - 4:13 pm
STI
-
GSP
19h 23m
2 stops
$563Delta
Wed, Jul 8 - Mon, Jul 13

Spirit Airlines flights from South Carolina to Santiago de los Caballeros

Our best Spirit Airlines deals on South Carolina to Santiago de los Caballeros flight tickets
Spirit Airlines
Mar 3
CLT5:55 amCharlotte Douglas
8h 40m
1 stop
STI3:35 pmSantiago de los Caballeros
Mar 10
STI3:41 pmSantiago de los Caballeros
8h 15m
1 stop
CLT11:56 pmCharlotte Douglas
$256
Spirit Airlines
Mar 17
CLT1:20 pmCharlotte Douglas
12h 29m
1 stop
STI1:49 amSantiago de los Caballeros
Mar 24
STI3:43 pmSantiago de los Caballeros
8h 55m
1 stop
CLT12:38 amCharlotte Douglas
$263
Spirit Airlines
Mar 16
CLT9:00 pmCharlotte Douglas
4h 49m
1 stop
STI1:49 amSantiago de los Caballeros
Mar 21
STI2:46 amSantiago de los Caballeros
5h 35m
1 stop
CLT8:21 amCharlotte Douglas
$273

American Airlines flights from South Carolina to Santiago de los Caballeros

Our best American Airlines deals on South Carolina to Santiago de los Caballeros flight tickets
American Airlines
Mar 11
CHS6:00 amCharleston
6h 30m
1 stop
STI12:30 pmSantiago de los Caballeros
Mar 18
STI7:00 amSantiago de los Caballeros
16h 55m
2 stops
CHS11:55 pmCharleston
$319
American Airlines
Mar 5
CHS8:13 pmCharleston
24h 17m
1 stop
STI9:30 pmSantiago de los Caballeros
Mar 12
STI1:30 pmSantiago de los Caballeros
10h 29m
1 stop
CHS11:59 pmCharleston
$322
American Airlines
May 13
CHS6:20 pmCharleston
18h 03m
2 stops
STI12:23 pmSantiago de los Caballeros
May 17
STI1:32 pmSantiago de los Caballeros
18h 59m
2 stops
CHS8:31 amCharleston
$324

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Tue 3/3

5:55 am-3:35 pm

1 stop8h 40m

Santiago de los Caballeros

Tue 3/10

3:41 pm-11:56 pm

1 stop8h 15m

$256

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Tue 3/17

1:20 pm-1:49 am

1 stop12h 29m

Santiago de los Caballeros

Tue 3/24

3:43 pm-12:38 am

1 stop8h 55m

$263

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 3/23

6:00 am-2:35 pm

1 stop8h 35m

Santiago de los Caballeros

Tue 3/31

3:28 pm-12:38 am

1 stop9h 10m

$269

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 3/16

1:20 pm-1:49 am

1 stop12h 29m

Santiago de los Caballeros

Mon 3/23

3:43 pm-12:38 am

1 stop8h 55m

$273

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 3/19

6:00 am-2:35 pm

1 stop8h 35m

Santiago de los Caballeros

Wed 3/25

2:46 am-8:21 am

1 stop5h 35m

$283

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 2/20

6:37 pm-3:35 pm

1 stop19h 58m

Santiago de los Caballeros

Wed 2/25

4:40 pm-1:54 pm

1 stop22h 14m

$298

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 2/19

11:00 am-3:35 pm

1 stop27h 35m

Santiago de los Caballeros

Wed 2/25

4:40 pm-1:54 pm

1 stop22h 14m

$301

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/11

6:00 am-12:30 pm

1 stop6h 30m

Santiago de los Caballeros

Wed 3/18

7:00 am-11:55 pm

2 stops16h 55m

$319

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 3/5

8:13 pm-9:30 pm

1 stop24h 17m

Santiago de los Caballeros

Thu 3/12

1:30 pm-11:59 pm

1 stop10h 29m

$322

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Wed 7/8

7:45 am-12:30 am

2 stops16h 45m

Santiago de los Caballeros

Mon 7/13

8:50 pm-4:13 pm

2 stops19h 23m

$563

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from South Carolina to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Santiago de los Caballeros flights?

You could potentially save up to 33% on your flight if you consider stops on a South Carolina to Santiago de los Caballeros flight.

Cheap South Carolina to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santiago de los Caballeros

Fastest flight time

4h 49m

Direct flights

None
The fastest flight from South Carolina to Santiago de los Caballeros takes 4h 49m
There are no direct flights from South Carolina to Santiago de los Caballeros. There are no popular flight routes from South Carolina to Santiago de los Caballeros.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Santiago de los Caballeros Airport?

    Prices for flights from South Carolina to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from South Carolina to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santiago de los Caballeros

Compare and see reviews for airlines that fly from South Carolina to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $438Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Santiago de los Caballeros for you.

Can I find flights from South Carolina to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Santiago de los Caballeros?

momondo helps you find the best flight between South Carolina and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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