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Cheap flights from South Carolina to Santiago de los Caballeros from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Santiago de los Caballeros departing on 8/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:30 am - 1:27 pm
CLT
-
STI
5h 57m
1 stop
JetBlue Logo
3:49 pm - 11:20 pm
STI
-
CLT
7h 31m
1 stop
$378JetBlue
Mon, Sep 28 - Thu, Oct 1
American Airlines Logo
10:20 am - 8:03 pm
CHS
-
STI
9h 43m
2 stops
American Airlines Logo
3:15 pm - 12:49 pm
STI
-
CHS
21h 34m
2 stops
$383American Airlines
Tue, Sep 8 - Thu, Sep 10
American Airlines Logo
7:45 pm - 2:15 pm
CLT
-
STI
18h 30m
1 stop
American Airlines Logo
3:16 pm - 9:57 am
STI
-
CLT
18h 41m
1 stop
$384American Airlines
Sat, Oct 3 - Sat, Oct 10
American Airlines Logo
11:00 am - 9:07 pm
CLT
-
STI
10h 07m
1 stop
American Airlines Logo
3:35 pm - 12:08 pm
STI
-
CLT
20h 33m
1 stop
$386American Airlines
Thu, Aug 27 - Tue, Sep 8
American Airlines Logo
9:06 am - 2:15 pm
CLT
-
STI
5h 09m
1 stop
American Airlines Logo
3:15 pm - 10:59 am
STI
-
CLT
19h 44m
1 stop
$391American Airlines
Wed, Sep 16 - Sun, Sep 20
JetBlue Logo
6:30 am - 3:01 pm
CLT
-
STI
8h 31m
1 stop
JetBlue Logo
4:54 pm - 11:20 pm
STI
-
CLT
6h 26m
1 stop
$434JetBlue
Mon, Aug 24 - Mon, Aug 31
Delta Logo
6:00 am - 7:34 pm
CLT
-
STI
13h 34m
1 stop
Delta Logo
8:59 pm - 1:09 pm
STI
-
CLT
16h 10m
1 stop
$440Delta
Fri, Jul 31 - Tue, Aug 4
Delta Logo
6:00 am - 7:34 pm
CLT
-
STI
13h 34m
1 stop
Delta Logo
8:59 pm - 1:26 pm
STI
-
CLT
16h 27m
2 stops
$445Delta
Fri, Jul 31 - Tue, Aug 4
United Airlines Logo
6:20 am - 10:52 pm
GSP
-
STI
16h 32m
1 stop
United Airlines Logo
6:00 am - 11:03 pm
STI
-
GSP
17h 03m
1 stop
$850United Airlines
Sat, Aug 8 - Tue, Aug 11
United Airlines Logo
1:48 pm - 10:52 pm
CAE
-
STI
9h 04m
1 stop
United Airlines Logo
4:23 pm - 11:11 am
STI
-
CAE
18h 48m
1 stop
$919United Airlines
Wed, Aug 12 - Wed, Aug 19

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American Airlines flights from South Carolina to Santiago de los Caballeros

Our best American Airlines deals on South Carolina to Santiago de los Caballeros flight tickets
American Airlines
Sep 8
CHS10:20 amCharleston
9h 43m
2 stops
STI8:03 pmSantiago de los Caballeros
Sep 10
STI3:15 pmSantiago de los Caballeros
21h 34m
2 stops
CHS12:49 pmCharleston
$383
American Airlines
Oct 3
CLT7:45 pmCharlotte Douglas
18h 30m
1 stop
STI2:15 pmSantiago de los Caballeros
Oct 10
STI3:16 pmSantiago de los Caballeros
18h 41m
1 stop
CLT9:57 amCharlotte Douglas
$384
American Airlines
Aug 27
CLT11:00 amCharlotte Douglas
10h 07m
1 stop
STI9:07 pmSantiago de los Caballeros
Sep 8
STI3:35 pmSantiago de los Caballeros
20h 33m
1 stop
CLT12:08 pmCharlotte Douglas
$386

Frontier flights from South Carolina to Santiago de los Caballeros

Our best Frontier deals on South Carolina to Santiago de los Caballeros flight tickets
Frontier
Jul 18
CLT10:02 pmCharlotte Douglas
11h 57m
1 stop
STI9:59 amSantiago de los Caballeros
Jul 21
STI11:14 amSantiago de los Caballeros
22h 42m
1 stop
CLT9:56 amCharlotte Douglas
$480
Frontier
Aug 5
CLT10:08 pmCharlotte Douglas
11h 51m
1 stop
STI9:59 amSantiago de los Caballeros
Aug 9
STI11:14 amSantiago de los Caballeros
22h 42m
1 stop
CLT9:56 amCharlotte Douglas
$565
Frontier
Jul 11
CLT10:02 pmCharlotte Douglas
11h 57m
1 stop
STI9:59 amSantiago de los Caballeros
Jul 14
STI11:14 amSantiago de los Caballeros
33h 53m
2 stops
CLT9:07 pmCharlotte Douglas
$856

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 30, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 9/28

7:30 am-1:27 pm

1 stop5h 57m

Santiago de los Caballeros

Thu 10/1

3:49 pm-11:20 pm

1 stop7h 31m

$378

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/8

10:20 am-8:03 pm

2 stops9h 43m

Santiago de los Caballeros

Thu 9/10

3:15 pm-12:49 pm

2 stops21h 34m

$383

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sat 10/3

7:45 pm-2:15 pm

1 stop18h 30m

Santiago de los Caballeros

Sat 10/10

3:16 pm-9:57 am

1 stop18h 41m

$384

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 8/27

11:00 am-9:07 pm

1 stop10h 07m

Santiago de los Caballeros

Tue 9/8

3:35 pm-12:08 pm

1 stop20h 33m

$386

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Wed 9/16

9:06 am-2:15 pm

1 stop5h 09m

Santiago de los Caballeros

Sun 9/20

3:15 pm-10:59 am

1 stop19h 44m

$391

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 8/24

6:30 am-3:01 pm

1 stop8h 31m

Santiago de los Caballeros

Mon 8/31

4:54 pm-11:20 pm

1 stop6h 26m

$434

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 7/31

6:00 am-7:34 pm

1 stop13h 34m

Santiago de los Caballeros

Tue 8/4

8:59 pm-1:09 pm

1 stop16h 10m

$440

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 7/31

6:00 am-7:34 pm

1 stop13h 34m

Santiago de los Caballeros

Tue 8/4

8:59 pm-1:26 pm

2 stops16h 27m

$445

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Sat 8/8

6:20 am-10:52 pm

1 stop16h 32m

Santiago de los Caballeros

Tue 8/11

6:00 am-11:03 pm

1 stop17h 03m

$850

ColumbiaSantiago de los Caballeros

CAE - STI

CAESTI

Columbia Metropolitan

Wed 8/12

1:48 pm-10:52 pm

1 stop9h 04m

Santiago de los Caballeros

Wed 8/19

4:23 pm-11:11 am

1 stop18h 48m

$919

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from South Carolina to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Santiago de los Caballeros flights?

You could potentially save up to 6% on your flight if you consider stops on a South Carolina to Santiago de los Caballeros flight.

Cheap South Carolina to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santiago de los Caballeros

Fastest flight time

4h 51m

Direct flights

None
The fastest flight from South Carolina to Santiago de los Caballeros takes 4h 51m
There are no direct flights from South Carolina to Santiago de los Caballeros. There are no popular flight routes from South Carolina to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from South Carolina to Santiago de los Caballeros

  • When did momondo last update prices for flights from South Carolina to Santiago de los Caballeros Airport?

    Prices for flights from South Carolina to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from South Carolina to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santiago de los Caballeros

Compare and see reviews for airlines that fly from South Carolina to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.1
11,762 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Santiago de los Caballeros for you.

Can I find flights from South Carolina to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Santiago de los Caballeros?

momondo helps you find the best flight between South Carolina and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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