How long does it take to fly to Santiago?

On average, it takes 12h 06m to fly from South Carolina to Santiago if you fly out of Charleston (the most popular airport in South Carolina) and into Santiago (the most popular airport in Santiago). If you’re flying out of Greenville and into Santiago, then the flight time is around 19h 55m.

What is the cheapest airline that flies from South Carolina to Santiago Arturo Merino Benitez?

American Airlines and United Airlines are the most popular carriers operating from South Carolina to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

LATAM Airlines, American Airlines and Delta are the top three most popular airlines that fly to Santiago from South Carolina according to our data. LATAM Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport?

Prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from South Carolina to Santiago Arturo Merino Benitez Airport?

There are 3 operators available for flights from South Carolina to Santiago Arturo Merino Benitez Airport as of October 2026.

How old do you have to be to fly from South Carolina to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$474 Cheap Flights from South Carolina to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 8:35 amCHS Charleston-SCL Santiago Arturo Merino Benitez

23h 35m1 stop Dallas/Fort Worth

11:15 pm - 1:04 pmSCL Santiago Arturo Merino Benitez-CHS Charleston

15h 49m1 stop Dallas/Fort Worth

$1,126American Airlines

Fri, Jan 29 - Mon, Feb 1

12:20 pm - 9:25 amCHS Charleston-SCL Santiago Arturo Merino Benitez

19h 05m2 stops Charlotte Douglas Miami

10:30 pm - 3:48 pmSCL Santiago Arturo Merino Benitez-CHS Charleston

19h 18m2 stops Miami Washington, D.C. Reagan-National

$1,130American Airlines

Fri, Jan 29 - Mon, Feb 1

12:20 pm - 9:25 amCHS Charleston-SCL Santiago Arturo Merino Benitez

19h 05m2 stops Charlotte Douglas Miami

11:15 pm - 3:08 pmSCL Santiago Arturo Merino Benitez-CHS Charleston

17h 53m2 stops Dallas/Fort Worth Charlotte Douglas

$1,130American Airlines

Fri, Jan 29 - Mon, Feb 1

4:58 pm - 8:50 amCHS Charleston-SCL Santiago Arturo Merino Benitez

13h 52m1 stop Houston George Bush Intcntl

10:45 pm - 4:12 pmSCL Santiago Arturo Merino Benitez-CHS Charleston

19h 27m1 stop Houston George Bush Intcntl

$1,156United Airlines

Sat, Feb 20 - Tue, Mar 9

6:49 am - 8:50 amGSP Greenville-SCL Santiago Arturo Merino Benitez

24h 01m1 stop Houston George Bush Intcntl

10:45 pm - 4:34 pmSCL Santiago Arturo Merino Benitez-GSP Greenville

19h 49m1 stop Houston George Bush Intcntl

$1,156United Airlines

Thu, Nov 26 - Thu, Dec 17

5:12 pm - 8:50 amGSP Greenville-SCL Santiago Arturo Merino Benitez

13h 38m1 stop Houston George Bush Intcntl

10:45 pm - 4:34 pmSCL Santiago Arturo Merino Benitez-GSP Greenville

19h 49m1 stop Houston George Bush Intcntl

$1,156United Airlines

Wed, Nov 25 - Thu, Dec 17

3:42 pm - 6:40 amGSP Greenville-SCL Santiago Arturo Merino Benitez

12h 58m1 stop Atlanta Hartsfield-Jackson

6:05 pm - 6:49 pmSCL Santiago Arturo Merino Benitez-GSP Greenville

26h 44m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,166LATAM Airlines

Wed, Feb 24 - Sun, Mar 7

12:00 pm - 5:20 amGSP Greenville-SCL Santiago Arturo Merino Benitez

15h 20m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

6:05 pm - 11:37 pmSCL Santiago Arturo Merino Benitez-GSP Greenville

31h 32m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,166LATAM Airlines

Wed, Feb 24 - Sun, Mar 7

6:00 am - 6:55 amCHS Charleston-SCL Santiago Arturo Merino Benitez

22h 55m1 stop New York John F Kennedy Intl

11:10 pm - 6:54 pmSCL Santiago Arturo Merino Benitez-CHS Charleston

21h 44m1 stop Atlanta Hartsfield-Jackson

$1,176Delta

Sat, Feb 20 - Tue, Mar 9

5:03 pm - 3:00 pmCHS Charleston-SCL Santiago Arturo Merino Benitez

19h 57m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:25 pm - 10:13 amSCL Santiago Arturo Merino Benitez-CHS Charleston

15h 48m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,206Delta

Fri, Jan 15 - Sun, Jan 24

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American Airlines flights from South Carolina to Santiago

Our best American Airlines deals on South Carolina to Santiago flight tickets

American Airlines

Jan 29

CHS7:00 amCharleston

23h 35m

1 stop

SCL8:35 amSantiago Arturo Merino Benitez

Feb 1

SCL11:15 pmSantiago Arturo Merino Benitez

15h 49m

1 stop

CHS1:04 pmCharleston

$1,126

American Airlines

Jan 29

CHS12:20 pmCharleston

19h 05m

2 stops

SCL9:25 amSantiago Arturo Merino Benitez

Feb 1

SCL11:15 pmSantiago Arturo Merino Benitez

17h 53m

2 stops

CHS3:08 pmCharleston

$1,130

American Airlines

Mar 1

GSP2:23 pmGreenville

15h 22m

1 stop

SCL7:45 amSantiago Arturo Merino Benitez

Mar 31

SCL9:35 pmSantiago Arturo Merino Benitez

18h 56m

2 stops

GSP3:31 pmGreenville

$1,160

LATAM Airlines flights from South Carolina to Santiago

Our best LATAM Airlines deals on South Carolina to Santiago flight tickets

LATAM Airlines

Feb 24

GSP3:42 pmGreenville

12h 58m

1 stop

SCL6:40 amSantiago Arturo Merino Benitez

Mar 7

SCL6:05 pmSantiago Arturo Merino Benitez

26h 44m

2 stops

GSP6:49 pmGreenville

$1,166

LATAM Airlines

Jan 15

CHS11:00 amCharleston

17h 40m

1 stop

SCL6:40 amSantiago Arturo Merino Benitez

Jan 24

SCL4:35 pmSantiago Arturo Merino Benitez

27h 42m

2 stops

CHS6:17 pmCharleston

$1,186

LATAM Airlines

Feb 24

GSP3:42 pmGreenville

12h 58m

1 stop

SCL6:40 amSantiago Arturo Merino Benitez

Mar 7

SCL11:10 pmSantiago Arturo Merino Benitez

12h 15m

1 stop

GSP9:25 amGreenville

$1,196

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Fri 1/29

7:00 am-8:35 am

1 stop23h 35m

Santiago Arturo Merino Benitez

Mon 2/1

11:15 pm-1:04 pm

1 stop15h 49m

$1,126

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Fri 1/29

12:20 pm-9:25 am

2 stops19h 05m

Santiago Arturo Merino Benitez

Mon 2/1

10:30 pm-3:48 pm

2 stops19h 18m

$1,130

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Fri 1/29

12:20 pm-9:25 am

2 stops19h 05m

Santiago Arturo Merino Benitez

Mon 2/1

11:15 pm-3:08 pm

2 stops17h 53m

$1,130

Quickest round-trip

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Sat 2/20

4:58 pm-8:50 am

1 stop13h 52m

Santiago Arturo Merino Benitez

Tue 3/9

10:45 pm-4:12 pm

1 stop19h 27m

$1,156

GreenvilleSantiago

GSP Greenville - SCL Santiago Arturo Merino Benitez

GSPSCL

Greenville

Thu 11/26

6:49 am-8:50 am

1 stop24h 01m

Santiago Arturo Merino Benitez

Thu 12/17

10:45 pm-4:34 pm

1 stop19h 49m

$1,156

GreenvilleSantiago

GSP Greenville - SCL Santiago Arturo Merino Benitez

GSPSCL

Greenville

Wed 11/25

5:12 pm-8:50 am

1 stop13h 38m

Santiago Arturo Merino Benitez

Thu 12/17

10:45 pm-4:34 pm

1 stop19h 49m

$1,156

GreenvilleSantiago

GSP Greenville - SCL Santiago Arturo Merino Benitez

GSPSCL

Greenville

Wed 2/24

3:42 pm-6:40 am

1 stop12h 58m

Santiago Arturo Merino Benitez

Sun 3/7

6:05 pm-6:49 pm

2 stops26h 44m

$1,166

GreenvilleSantiago

GSP Greenville - SCL Santiago Arturo Merino Benitez

GSPSCL

Greenville

Wed 2/24

12:00 pm-5:20 am

2 stops15h 20m

Santiago Arturo Merino Benitez

Sun 3/7

6:05 pm-11:37 pm

2 stops31h 32m

$1,166

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Sat 2/20

6:00 am-6:55 am

1 stop22h 55m

Santiago Arturo Merino Benitez

Tue 3/9

11:10 pm-6:54 pm

1 stop21h 44m

$1,176

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Fri 1/15

5:03 pm-3:00 pm

2 stops19h 57m

Santiago Arturo Merino Benitez

Sun 1/24

8:25 pm-10:13 am

2 stops15h 48m

$1,206

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from South Carolina to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you don’t want to visit Santiago in October, then you should wait until March to fly from South Carolina, when ticket prices are also cheap, with an average price of $844.

Cheap South Carolina to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santiago

Best Price Found	$474
Fastest flight time	12h 16m
Direct flights	None

The best one-way flight to Santiago from South Carolina in the past 72 hours is $474. The best round-trip flight deal from South Carolina to Santiago found on momondo in the last 72 hours is $1,126.

The fastest flight from South Carolina to Santiago takes 12h 16m

There are no direct flights from South Carolina to Santiago. There are no popular flight routes from South Carolina to Santiago.

Search flight deals

Frequently asked questions about flying from South Carolina to Santiago

When did momondo last update prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport?
Prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Santiago Arturo Merino Benitez Airport?
There are 3 operators available for flights from South Carolina to Santiago Arturo Merino Benitez Airport as of October 2026.
How old do you have to be to fly from South Carolina to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santiago

Compare and see reviews for airlines that fly from South Carolina to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $704	Free Cancellation	Rating 7.0 12,210 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $745	Free Cancellation	Rating 7.4 1,970 reviews	Search LATAM Airlines flights
Delta	PriceFrom $763	Free Cancellation	Rating 7.8 8,694 reviews	Search Delta flights

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Why should I use momondo to find a flight deal from South Carolina to Santiago?

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Can I find flights from South Carolina to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Santiago?

momondo helps you find the best flight between South Carolina and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from South Carolina and alert you when they change.