What airlines fly to Santiago?

LATAM Airlines, Delta and American Airlines are the top three most popular airlines that fly to Santiago from South Carolina according to our data. LATAM Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Santiago Arturo Merino Benitez?

LATAM Airlines and American Airlines are the most popular carriers operating from South Carolina to Santiago Arturo Merino Benitez

How long does it take to fly to Santiago?

On average, it takes 14h 39m to fly from South Carolina to Santiago if you fly out of Charleston (the most popular airport in South Carolina) and into Santiago (the most popular airport in Santiago). If you’re flying out of Greenville and into Santiago, then the flight time is around 19h 58m.

When did momondo last update prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport?

Prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from South Carolina to Santiago Arturo Merino Benitez Airport?

There are 3 operators available for flights from South Carolina to Santiago Arturo Merino Benitez Airport as of April 2026.

How old do you have to be to fly from South Carolina to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$314 Cheap Flights from South Carolina to Santiago in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:12 am - 1:30 pm

CLT

SCL

30h 18m

3 stops

3:35 am - 12:03 pm

SCL

CLT

32h 28m

3 stops

$670Multiple Airlines

Wed, May 13 - Tue, May 19

7:12 am - 1:30 pm

CLT

SCL

30h 18m

3 stops

3:35 am - 12:03 pm

SCL

CLT

32h 28m

3 stops

$673Multiple Airlines

Wed, May 13 - Tue, May 19

7:12 am - 1:30 pm

CLT

SCL

30h 18m

3 stops

3:35 am - 12:03 pm

SCL

CLT

32h 28m

3 stops

$690Multiple Airlines

Wed, May 13 - Tue, May 19

7:59 pm - 8:15 am

CHS

SCL

11h 16m

1 stop

12:00 am - 6:54 pm

SCL

CHS

19h 54m

2 stops

$856LATAM Airlines

Mon, Oct 5 - Mon, Oct 12

5:55 pm - 7:15 am

CHS

SCL

13h 20m

1 stop

11:05 pm - 11:57 pm

SCL

CHS

24h 52m

2 stops

$875LATAM Airlines

Sat, Aug 15 - Sun, Aug 23

11:06 am - 6:50 am

CHS

SCL

19h 44m

2 stops

8:30 pm - 2:37 pm

SCL

CHS

18h 07m

2 stops

$880American Airlines

Thu, Aug 13 - Wed, Aug 26

8:00 pm - 6:50 am

GSP

SCL

10h 50m

1 stop

8:30 pm - 6:10 pm

SCL

GSP

21h 40m

1 stop

$975American Airlines

Wed, Jul 22 - Sun, Aug 16

11:43 am - 6:25 am

SAV

SCL

18h 42m

1 stop

8:40 pm - 4:11 pm

SCL

SAV

19h 31m

1 stop

$1,155Delta

Thu, Jun 4 - Thu, Jun 11

7:00 am - 1:50 am

SAV

SCL

18h 50m

2 stops

12:43 am - 6:22 pm

SCL

SAV

17h 39m

2 stops

$1,203United Airlines

Tue, Jun 23 - Mon, Jul 27

7:00 am - 5:03 am

SAV

SCL

22h 03m

2 stops

11:22 am - 9:53 pm

SCL

SAV

34h 31m

2 stops

$1,378United Airlines

Mon, Aug 24 - Wed, Aug 26

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Delta flights from South Carolina to Santiago

Our best Delta deals on South Carolina to Santiago flight tickets

Delta

Jun 25

GSP1:09 pmGreenville

18h 06m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Aug 6

SCL8:40 pmSantiago Arturo Merino Benitez

15h 33m

1 stop

GSP12:13 pmGreenville

$1,115

Delta

Jun 4

SAV11:43 amSavannah/Hilton Head

18h 42m

1 stop

SCL6:25 amSantiago Arturo Merino Benitez

Jun 11

SCL8:40 pmSantiago Arturo Merino Benitez

19h 31m

1 stop

SAV4:11 pmSavannah/Hilton Head

$1,155

Delta

May 28

GSP11:28 amGreenville

19h 47m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Jun 4

SCL8:40 pmSantiago Arturo Merino Benitez

14h 00m

1 stop

GSP10:40 amGreenville

$1,215

American Airlines flights from South Carolina to Santiago

Our best American Airlines deals on South Carolina to Santiago flight tickets

American Airlines

Apr 28

CLT11:01 amCharlotte Douglas

20h 04m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

May 27

SCL9:00 pmSantiago Arturo Merino Benitez

21h 17m

1 stop

CLT6:17 pmCharlotte Douglas

$865

American Airlines

Apr 28

CLT2:44 pmCharlotte Douglas

16h 21m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

May 27

SCL9:00 pmSantiago Arturo Merino Benitez

16h 26m

2 stops

CLT1:26 pmCharlotte Douglas

$870

American Airlines

Aug 13

CHS11:06 amCharleston

19h 44m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 26

SCL8:30 pmSantiago Arturo Merino Benitez

18h 07m

2 stops

CHS2:37 pmCharleston

$880

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 5/13

7:12 am-1:30 pm

3 stops30h 18m

Santiago Arturo Merino Benitez

Tue 5/19

3:35 am-12:03 pm

3 stops32h 28m

$670

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 5/13

7:12 am-1:30 pm

3 stops30h 18m

Santiago Arturo Merino Benitez

Tue 5/19

3:35 am-12:03 pm

3 stops32h 28m

$673

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 5/13

7:12 am-1:30 pm

3 stops30h 18m

Santiago Arturo Merino Benitez

Tue 5/19

3:35 am-12:03 pm

3 stops32h 28m

$690

Quickest round-trip

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 10/5

7:59 pm-8:15 am

1 stop11h 16m

Santiago Arturo Merino Benitez

Mon 10/12

12:00 am-6:54 pm

2 stops19h 54m

$856

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 8/15

5:55 pm-7:15 am

1 stop13h 20m

Santiago Arturo Merino Benitez

Sun 8/23

11:05 pm-11:57 pm

2 stops24h 52m

$875

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 8/13

11:06 am-6:50 am

2 stops19h 44m

Santiago Arturo Merino Benitez

Wed 8/26

8:30 pm-2:37 pm

2 stops18h 07m

$880

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 7/22

8:00 pm-6:50 am

1 stop10h 50m

Santiago Arturo Merino Benitez

Sun 8/16

8:30 pm-6:10 pm

1 stop21h 40m

$975

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Thu 6/4

11:43 am-6:25 am

1 stop18h 42m

Santiago Arturo Merino Benitez

Thu 6/11

8:40 pm-4:11 pm

1 stop19h 31m

$1,155

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Tue 6/23

7:00 am-1:50 am

2 stops18h 50m

Santiago Arturo Merino Benitez

Mon 7/27

12:43 am-6:22 pm

2 stops17h 39m

$1,203

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Mon 8/24

7:00 am-5:03 am

2 stops22h 03m

Santiago Arturo Merino Benitez

Wed 8/26

11:22 am-9:53 pm

2 stops34h 31m

$1,378

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on South Carolina to Santiago flights?

You could potentially save up to 12% on your flight if you consider stops on a South Carolina to Santiago flight.

Cheap South Carolina to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santiago

Fastest flight time	11h 16m
Direct flights	None

The fastest flight from South Carolina to Santiago takes 11h 16m

There are no direct flights from South Carolina to Santiago. There are no popular flight routes from South Carolina to Santiago.

Search flight deals

Frequently asked questions about flying from South Carolina to Santiago

When did momondo last update prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport?
Prices for flights from South Carolina to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Santiago Arturo Merino Benitez Airport?
There are 3 operators available for flights from South Carolina to Santiago Arturo Merino Benitez Airport as of April 2026.
How old do you have to be to fly from South Carolina to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santiago

Compare and see reviews for airlines that fly from South Carolina to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $562	Free Cancellation	Rating 7.4 1,908 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $703	Free Cancellation	Rating 7.1 11,605 reviews	Search American Airlines flights
Delta	PriceFrom $753	Free Cancellation	Rating 7.9 8,427 reviews	Search Delta flights

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Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Santiago?

momondo helps you find the best flight between South Carolina and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from South Carolina and alert you when they change.