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Cheap flights from South Carolina to Prague from $297

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Prague departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from South Carolina to Prague

Cheap round-trip flights

Scandinavian Airlines Logo
1:15 pm - 9:45 amCLT-PRG
14h 30m2 stops
Scandinavian Airlines Logo
3:00 pm - 10:23 pmPRG-CLT
37h 23m2 stops
$513Scandinavian Airlines
Find Deal
Thu, Feb 19 - Thu, Feb 26
Scandinavian Airlines Logo
10:00 am - 9:45 amCLT-PRG
17h 45m2 stops
Scandinavian Airlines Logo
10:25 am - 11:54 pmPRG-CLT
19h 29m2 stops
$535Scandinavian Airlines
Find Deal
Sat, Jan 31 - Mon, Feb 9
Multiple Airlines Logo
6:00 am - 8:15 pmCLT-PRG
32h 15m3 stops
Multiple Airlines Logo
7:20 pm - 6:36 pmPRG-CLT
29h 16m3 stops
$551Multiple Airlines
Find Deal
Tue, Oct 21 - Tue, Nov 4
Lufthansa Logo
6:40 pm - 12:55 pmCLT-PRG
12h 15m1 stop
Lufthansa Logo
6:15 am - 4:55 pmPRG-CLT
16h 40m1 stop
$586Lufthansa
Find Deal
Sun, Oct 19 - Tue, Nov 4
Lufthansa Logo
10:25 am - 9:40 amCLT-PRG
17h 15m2 stops
Lufthansa Logo
6:15 am - 4:55 pmPRG-CLT
16h 40m1 stop
$587Lufthansa
Find Deal
Tue, Oct 21 - Tue, Nov 4
Multiple Airlines Logo
8:52 am - 3:40 pmCLT-PRG
24h 48m2 stops
Multiple Airlines Logo
7:20 pm - 6:36 pmPRG-CLT
29h 16m3 stops
$604Multiple Airlines
Find Deal
Thu, Oct 23 - Thu, Nov 6
American Airlines Logo
11:35 pm - 11:35 pmCLT-PRG
18h 00m1 stop
American Airlines Logo
6:45 am - 6:55 pmPRG-CLT
18h 10m1 stop
$609American Airlines
Find Deal
Tue, Oct 21 - Tue, Nov 4
Delta Logo
5:25 pm - 5:05 pmCLT-PRG
17h 40m2 stops
Delta Logo
6:00 am - 8:14 pmPRG-CLT
20h 14m2 stops
$613Delta
Find Deal
Tue, Nov 4 - Tue, Nov 11
Delta Logo
1:45 pm - 5:35 pmGSP-PRG
21h 50m2 stops
Delta Logo
6:00 am - 9:25 pmPRG-GSP
21h 25m2 stops
$625Delta
Find Deal
Wed, Nov 5 - Wed, Nov 12
American Airlines Logo
4:18 pm - 6:05 pmCAE-PRG
19h 47m2 stops
American Airlines Logo
10:30 am - 9:47 pmPRG-CAE
17h 17m2 stops
$674American Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13

Scandinavian Airlines flights from South Carolina to Prague

Our best Scandinavian Airlines deals on South Carolina to Prague flight tickets
Scandinavian Airlines
Feb 19
CLT1:15 pmCharlotte Douglas
14h 30m
2 stops
PRG9:45 amVáclav Havel Prague
Feb 26
PRG3:00 pmVáclav Havel Prague
37h 23m
2 stops
CLT10:23 pmCharlotte Douglas
$513
Find similar
Scandinavian Airlines
Jan 31
CLT10:00 amCharlotte Douglas
17h 45m
2 stops
PRG9:45 amVáclav Havel Prague
Feb 9
PRG10:25 amVáclav Havel Prague
19h 29m
2 stops
CLT11:54 pmCharlotte Douglas
$535
Find similar
Scandinavian Airlines
Oct 24
CLT10:02 amCharlotte Douglas
42h 43m
2 stops
PRG10:45 amVáclav Havel Prague
Oct 31
PRG10:25 amVáclav Havel Prague
16h 22m
2 stops
CLT9:47 pmCharlotte Douglas
$539
Find similar

Delta flights from South Carolina to Prague

Our best Delta deals on South Carolina to Prague flight tickets
Delta
Nov 4
CLT5:25 pmCharlotte Douglas
17h 40m
2 stops
PRG5:05 pmVáclav Havel Prague
Nov 11
PRG6:00 amVáclav Havel Prague
20h 14m
2 stops
CLT8:14 pmCharlotte Douglas
$613
Find similar
Delta
Nov 5
GSP1:45 pmGreenville
21h 50m
2 stops
PRG5:35 pmVáclav Havel Prague
Nov 12
PRG6:00 amVáclav Havel Prague
21h 25m
2 stops
GSP9:25 pmGreenville
$625
Find similar
Delta
Nov 12
AGS3:59 pmAugusta Bush Field
19h 06m
2 stops
PRG5:05 pmVáclav Havel Prague
Nov 16
PRG6:00 amVáclav Havel Prague
18h 51m
2 stops
AGS6:51 pmAugusta Bush Field
$663
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Thu 2/19

1:15 pm-9:45 am

2 stops14h 30m

Václav Havel Prague

Thu 2/26

3:00 pm-10:23 pm

2 stops37h 23m

$513

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sat 1/31

10:00 am-9:45 am

2 stops17h 45m

Václav Havel Prague

Mon 2/9

10:25 am-11:54 pm

2 stops19h 29m

$535

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 10/21

6:00 am-8:15 pm

3 stops32h 15m

Václav Havel Prague

Tue 11/4

7:20 pm-6:36 pm

3 stops29h 16m

$551

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 10/19

6:40 pm-12:55 pm

1 stop12h 15m

Václav Havel Prague

Tue 11/4

6:15 am-4:55 pm

1 stop16h 40m

$586

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 10/21

10:25 am-9:40 am

2 stops17h 15m

Václav Havel Prague

Tue 11/4

6:15 am-4:55 pm

1 stop16h 40m

$587

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Thu 10/23

8:52 am-3:40 pm

2 stops24h 48m

Václav Havel Prague

Thu 11/6

7:20 pm-6:36 pm

3 stops29h 16m

$604

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 10/21

11:35 pm-11:35 pm

1 stop18h 00m

Václav Havel Prague

Tue 11/4

6:45 am-6:55 pm

1 stop18h 10m

$609

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 11/4

5:25 pm-5:05 pm

2 stops17h 40m

Václav Havel Prague

Tue 11/11

6:00 am-8:14 pm

2 stops20h 14m

$613

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Wed 11/5

1:45 pm-5:35 pm

2 stops21h 50m

Václav Havel Prague

Wed 11/12

6:00 am-9:25 pm

2 stops21h 25m

$625

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Thu 11/6

4:18 pm-6:05 pm

2 stops19h 47m

Václav Havel Prague

Thu 11/13

10:30 am-9:47 pm

2 stops17h 17m

$674

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Prague from

How to get the cheapest flight ticket from South Carolina to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from South Carolina to Prague is on a Wednesday. Travelers who choose to depart for Prague on a Wednesday will often find tickets for as low as $949. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Prague for around $1,437.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the evening. momondo users have found flights departing from South Carolina to Prague in the evening for as low as $957. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $1,296. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap South Carolina to Prague flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Prague

Direct flights

None
There are no direct flights from South Carolina to Prague. There are no popular flight routes from South Carolina to Prague.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Václav Havel Prague Airport?

    Prices for flights from South Carolina to Václav Havel Prague Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Václav Havel Prague Airport?

  • How old do you have to be to fly from South Carolina to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The necessary travel and health documents for your Václav Havel Prague Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Prague

Compare and see reviews for airlines that fly from South Carolina to Prague with momondo
Airline
Rating
Free Cancellation
Price
KLMPriceFrom $692Free CancellationRating
7.8
1,387 reviews
Search KLM flights
United AirlinesPriceFrom $693Free CancellationRating
7.4
8,922 reviews
Search United Airlines flights
DeltaPriceFrom $757Free CancellationRating
7.9
7,971 reviews
Search Delta flights

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Prague?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Prague for you.

Can I find flights from South Carolina to Prague with flexible booking policies on momondo?

Flights from South Carolina to Prague with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from South Carolina to Prague?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Prague.

I’m not ready to book a flight from South Carolina to Prague right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Prague flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Prague trip

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