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Cheap flights from South Carolina to Prague from $344

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Prague departing on 11/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Prague

Cheap round-trip flights

Enter your travel dates to find the best prices.
British Airways Logo
6:24 pm - 5:05 pm
CLT
-
PRG
16h 41m
2 stops
British Airways Logo
6:30 am - 5:42 pm
PRG
-
CLT
17h 12m
2 stops
$704British Airways
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
11:20 pm - 10:50 pm
CLT
-
PRG
17h 30m
1 stop
American Airlines Logo
10:15 am - 9:55 pm
PRG
-
CLT
17h 40m
1 stop
$707American Airlines
Mon, Aug 17 - Tue, Aug 25
Multiple Airlines Logo
1:02 pm - 11:10 am
CLT
-
PRG
16h 08m
2 stops
Multiple Airlines Logo
10:55 am - 2:20 pm
PRG
-
CLT
33h 25m
1 stop
$712Multiple Airlines
Tue, Aug 25 - Sat, Nov 21
KLM Logo
6:02 am - 9:00 am
CLT
-
PRG
20h 58m
1 stop
KLM Logo
11:00 am - 10:58 pm
PRG
-
CLT
17h 58m
1 stop
$715KLM
Wed, Aug 12 - Wed, Aug 19
Multiple Airlines Logo
1:15 pm - 9:05 am
CLT
-
PRG
14h 50m
2 stops
Multiple Airlines Logo
8:55 am - 6:16 pm
PRG
-
CLT
15h 21m
2 stops
$716Multiple Airlines
Wed, Oct 28 - Mon, Nov 2
Scandinavian Airlines Logo
4:30 pm - 2:20 pm
CHS
-
PRG
15h 50m
2 stops
Scandinavian Airlines Logo
10:25 am - 8:42 pm
PRG
-
CHS
16h 17m
2 stops
$719Scandinavian Airlines
Mon, Nov 2 - Tue, Nov 10
Scandinavian Airlines Logo
5:10 pm - 6:40 pm
CAE
-
PRG
19h 30m
2 stops
Scandinavian Airlines Logo
8:50 pm - 11:54 pm
PRG
-
CAE
33h 04m
2 stops
$719Scandinavian Airlines
Wed, Nov 11 - Sun, Nov 15
Delta Logo
6:45 am - 9:00 am
CLT
-
PRG
20h 15m
2 stops
Delta Logo
11:00 am - 11:57 pm
PRG
-
CLT
18h 57m
2 stops
$719Delta
Wed, Aug 12 - Wed, Aug 19
Delta Logo
5:25 pm - 5:05 pm
CHS
-
PRG
17h 40m
2 stops
Delta Logo
6:00 am - 8:42 pm
PRG
-
CHS
20h 42m
2 stops
$810Delta
Sat, Nov 7 - Wed, Nov 11
KLM Logo
5:35 pm - 9:00 am
SAV
-
PRG
33h 25m
1 stop
KLM Logo
11:00 am - 9:39 pm
PRG
-
SAV
16h 39m
1 stop
$848KLM
Sat, Sep 12 - Wed, Sep 16

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American Airlines flights from South Carolina to Prague

Our best American Airlines deals on South Carolina to Prague flight tickets
American Airlines
Aug 17
CLT11:20 pmCharlotte Douglas
17h 30m
1 stop
PRG10:50 pmVáclav Havel Prague
Aug 25
PRG10:15 amVáclav Havel Prague
17h 40m
1 stop
CLT9:55 pmCharlotte Douglas
$707
American Airlines
Aug 17
CLT8:15 pmCharlotte Douglas
14h 45m
1 stop
PRG5:00 pmVáclav Havel Prague
Aug 25
PRG10:15 amVáclav Havel Prague
14h 35m
2 stops
CLT6:50 pmCharlotte Douglas
$711
American Airlines
Aug 12
CLT11:20 pmCharlotte Douglas
17h 35m
1 stop
PRG10:55 pmVáclav Havel Prague
Aug 19
PRG6:30 amVáclav Havel Prague
15h 12m
2 stops
CLT3:42 pmCharlotte Douglas
$725

KLM flights from South Carolina to Prague

Our best KLM deals on South Carolina to Prague flight tickets
KLM
Aug 12
CLT6:02 amCharlotte Douglas
20h 58m
1 stop
PRG9:00 amVáclav Havel Prague
Aug 19
PRG11:00 amVáclav Havel Prague
17h 58m
1 stop
CLT10:58 pmCharlotte Douglas
$715
KLM
Aug 25
CLT1:17 pmCharlotte Douglas
13h 03m
2 stops
PRG8:20 amVáclav Havel Prague
Dec 12
PRG6:00 amVáclav Havel Prague
18h 16m
2 stops
CLT6:16 pmCharlotte Douglas
$732
KLM
Jul 30
CLT6:02 amCharlotte Douglas
20h 58m
1 stop
PRG9:00 amVáclav Havel Prague
Aug 13
PRG11:00 amVáclav Havel Prague
13h 51m
1 stop
CLT6:51 pmCharlotte Douglas
$736

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:24 pm-5:05 pm

2 stops16h 41m

Václav Havel Prague

Wed 8/19

6:30 am-5:42 pm

2 stops17h 12m

$704

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 8/17

11:20 pm-10:50 pm

1 stop17h 30m

Václav Havel Prague

Tue 8/25

10:15 am-9:55 pm

1 stop17h 40m

$707

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 8/25

1:02 pm-11:10 am

2 stops16h 08m

Václav Havel Prague

Sat 11/21

10:55 am-2:20 pm

1 stop33h 25m

$712

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:02 am-9:00 am

1 stop20h 58m

Václav Havel Prague

Wed 8/19

11:00 am-10:58 pm

1 stop17h 58m

$715
Quickest round-trip

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 10/28

1:15 pm-9:05 am

2 stops14h 50m

Václav Havel Prague

Mon 11/2

8:55 am-6:16 pm

2 stops15h 21m

$716

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Mon 11/2

4:30 pm-2:20 pm

2 stops15h 50m

Václav Havel Prague

Tue 11/10

10:25 am-8:42 pm

2 stops16h 17m

$719

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Wed 11/11

5:10 pm-6:40 pm

2 stops19h 30m

Václav Havel Prague

Sun 11/15

8:50 pm-11:54 pm

2 stops33h 04m

$719

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:45 am-9:00 am

2 stops20h 15m

Václav Havel Prague

Wed 8/19

11:00 am-11:57 pm

2 stops18h 57m

$719

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Sat 11/7

5:25 pm-5:05 pm

2 stops17h 40m

Václav Havel Prague

Wed 11/11

6:00 am-8:42 pm

2 stops20h 42m

$810

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Sat 9/12

5:35 pm-9:00 am

1 stop33h 25m

Václav Havel Prague

Wed 9/16

11:00 am-9:39 pm

1 stop16h 39m

$848

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Prague from

How to get the cheapest flight ticket from South Carolina to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Prague?

In general, April is the cheapest month to fly from South Carolina to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Prague during the month of April, then departing from South Carolina during the month February is also very affordable. Most momondo users find prices during this month for around $0.

Can stopping save me money on South Carolina to Prague flights?

You could potentially save up to 62% on your flight if you consider stops on a South Carolina to Prague flight.

Cheap South Carolina to Prague flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Prague

Fastest flight time

12h 00m

Direct flights

None
The fastest flight from South Carolina to Prague takes 12h 00m
There are no direct flights from South Carolina to Prague. There are no popular flight routes from South Carolina to Prague.
Search flight deals

Frequently asked questions about flying from South Carolina to Prague

  • When did momondo last update prices for flights from South Carolina to Václav Havel Prague Airport?

    Prices for flights from South Carolina to Václav Havel Prague Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Václav Havel Prague Airport?

  • How old do you have to be to fly from South Carolina to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The necessary travel and health documents for your Václav Havel Prague Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Prague

Compare and see reviews for airlines that fly from South Carolina to Prague with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $485Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
United AirlinesPriceFrom $627Free CancellationRating
7.4
9,796 reviews
Search United Airlines flights

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Prague?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Prague for you.

Can I find flights from South Carolina to Prague with flexible booking policies on momondo?

Flights from South Carolina to Prague with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from South Carolina to Prague?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Prague.

I’m not ready to book a flight from South Carolina to Prague right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Prague flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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