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Cheap flights from South Carolina to Prague from $320

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Prague departing on 11/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Prague

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:53 pm - 9:05 amCHS-PRG
14h 12m2 stops
Multiple Airlines Logo
6:00 am - 5:06 pmPRG-CHS
17h 06m2 stops
$499Multiple Airlines
Find Deal
Sat, Dec 6 - Sat, Dec 13
Lufthansa Logo
10:51 am - 4:05 pmGSP-PRG
23h 14m2 stops
Lufthansa Logo
7:25 am - 7:29 pmPRG-GSP
18h 04m2 stops
$500Lufthansa
Find Deal
Mon, Jan 12 - Tue, Jan 20
United Airlines Logo
10:51 am - 4:05 pmGSP-PRG
23h 14m2 stops
United Airlines Logo
10:25 am - 8:47 pmPRG-GSP
16h 22m2 stops
$506United Airlines
Find Deal
Sun, Jan 11 - Mon, Jan 19
United Airlines Logo
2:50 pm - 4:05 pmCHS-PRG
19h 15m2 stops
United Airlines Logo
7:25 am - 2:48 pmPRG-CHS
37h 23m2 stops
$506United Airlines
Find Deal
Wed, Dec 31 - Sun, Jan 18
Scandinavian Airlines Logo
2:10 pm - 8:25 pmCLT-PRG
24h 15m2 stops
Scandinavian Airlines Logo
10:25 am - 10:00 pmPRG-CLT
17h 35m2 stops
$510Scandinavian Airlines
Find Deal
Thu, Feb 19 - Thu, Feb 26
Scandinavian Airlines Logo
6:00 am - 9:45 amCLT-PRG
21h 45m2 stops
Scandinavian Airlines Logo
10:25 am - 10:12 pmPRG-CLT
17h 47m2 stops
$532Scandinavian Airlines
Find Deal
Wed, Feb 4 - Tue, Feb 10
Air Canada Logo
9:30 am - 12:45 pmCLT-PRG
21h 15m2 stops
Air Canada Logo
6:10 am - 9:00 pmPRG-CLT
20h 50m2 stops
$673Air Canada
Find Deal
Wed, Apr 1 - Wed, Apr 8
Delta Logo
8:15 am - 11:40 amCLT-PRG
21h 25m2 stops
Delta Logo
2:30 pm - 6:13 pmPRG-CLT
33h 43m2 stops
$675Delta
Find Deal
Wed, Dec 31 - Mon, Jan 12
Delta Logo
12:23 pm - 10:50 amCHS-PRG
16h 27m2 stops
Delta Logo
2:30 pm - 11:58 pmPRG-CHS
15h 28m2 stops
$687Delta
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Thu, Jan 1 - Sat, Jan 17
Air Canada Logo
11:49 am - 1:05 pmGSP-PRG
19h 16m3 stops
Air Canada Logo
7:25 am - 11:48 pmPRG-GSP
22h 23m3 stops
$704Air Canada
Find Deal
Mon, Jan 12 - Tue, Jan 20

Lufthansa flights from South Carolina to Prague

Our best Lufthansa deals on South Carolina to Prague flight tickets
Lufthansa
Jan 12
GSP10:51 amGreenville
23h 14m
2 stops
PRG4:05 pmVáclav Havel Prague
Jan 20
PRG7:25 amVáclav Havel Prague
18h 04m
2 stops
GSP7:29 pmGreenville
$500
Find similar
Lufthansa
Mar 16
CLT7:50 pmCharlotte Douglas
15h 15m
1 stop
PRG4:05 pmVáclav Havel Prague
Mar 24
PRG6:15 amVáclav Havel Prague
16h 40m
1 stop
CLT5:55 pmCharlotte Douglas
$626
Find similar
Lufthansa
Mar 16
CLT7:40 pmCharlotte Douglas
15h 25m
2 stops
PRG4:05 pmVáclav Havel Prague
Mar 24
PRG6:15 amVáclav Havel Prague
16h 40m
1 stop
CLT5:55 pmCharlotte Douglas
$630
Find similar

United Airlines flights from South Carolina to Prague

Our best United Airlines deals on South Carolina to Prague flight tickets
United Airlines
Jan 11
GSP10:51 amGreenville
23h 14m
2 stops
PRG4:05 pmVáclav Havel Prague
Jan 19
PRG10:25 amVáclav Havel Prague
16h 22m
2 stops
GSP8:47 pmGreenville
$506
Find similar
United Airlines
Jan 5
CHS7:45 pmCharleston
35h 20m
2 stops
PRG1:05 pmVáclav Havel Prague
Jan 15
PRG7:35 amVáclav Havel Prague
16h 24m
2 stops
CHS5:59 pmCharleston
$597
Find similar
United Airlines
Jan 6
CLT6:50 pmCharlotte Douglas
15h 15m
1 stop
PRG4:05 pmVáclav Havel Prague
Jan 15
PRG1:45 pmVáclav Havel Prague
33h 10m
1 stop
CLT4:55 pmCharlotte Douglas
$663
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 9, 2025.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Sat 12/6

12:53 pm-9:05 am

2 stops14h 12m

Václav Havel Prague

Sat 12/13

6:00 am-5:06 pm

2 stops17h 06m

$499

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Mon 1/12

10:51 am-4:05 pm

2 stops23h 14m

Václav Havel Prague

Tue 1/20

7:25 am-7:29 pm

2 stops18h 04m

$500

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Sun 1/11

10:51 am-4:05 pm

2 stops23h 14m

Václav Havel Prague

Mon 1/19

10:25 am-8:47 pm

2 stops16h 22m

$506

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Wed 12/31

2:50 pm-4:05 pm

2 stops19h 15m

Václav Havel Prague

Sun 1/18

7:25 am-2:48 pm

2 stops37h 23m

$506

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Thu 2/19

2:10 pm-8:25 pm

2 stops24h 15m

Václav Havel Prague

Thu 2/26

10:25 am-10:00 pm

2 stops17h 35m

$510

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 2/4

6:00 am-9:45 am

2 stops21h 45m

Václav Havel Prague

Tue 2/10

10:25 am-10:12 pm

2 stops17h 47m

$532

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/1

9:30 am-12:45 pm

2 stops21h 15m

Václav Havel Prague

Wed 4/8

6:10 am-9:00 pm

2 stops20h 50m

$673

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 12/31

8:15 am-11:40 am

2 stops21h 25m

Václav Havel Prague

Mon 1/12

2:30 pm-6:13 pm

2 stops33h 43m

$675

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Thu 1/1

12:23 pm-10:50 am

2 stops16h 27m

Václav Havel Prague

Sat 1/17

2:30 pm-11:58 pm

2 stops15h 28m

$687

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Mon 1/12

11:49 am-1:05 pm

3 stops19h 16m

Václav Havel Prague

Tue 1/20

7:25 am-11:48 pm

3 stops22h 23m

$704

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Prague from

How to get the cheapest flight ticket from South Carolina to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from South Carolina to Prague is on a Wednesday. Travelers who choose to depart for Prague on a Wednesday will often find tickets for as low as $949. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Prague for around $1,437.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the evening. momondo users have found flights departing from South Carolina to Prague in the evening for as low as $957. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $1,296. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on South Carolina to Prague flights?

You could potentially save up to 41% on your flight if you consider stops on a South Carolina to Prague flight.

Cheap South Carolina to Prague flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Prague

Direct flights

None
There are no direct flights from South Carolina to Prague. There are no popular flight routes from South Carolina to Prague.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Václav Havel Prague Airport?

    Prices for flights from South Carolina to Václav Havel Prague Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Václav Havel Prague Airport?

  • How old do you have to be to fly from South Carolina to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The necessary travel and health documents for your Václav Havel Prague Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Prague

Compare and see reviews for airlines that fly from South Carolina to Prague with momondo
Airline
Rating
Free Cancellation
Price
KLMPriceFrom $692Free CancellationRating
7.7
1,409 reviews
Search KLM flights
United AirlinesPriceFrom $693Free CancellationRating
7.4
9,014 reviews
Search United Airlines flights
DeltaPriceFrom $735Free CancellationRating
7.9
8,000 reviews
Search Delta flights

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Prague?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Prague for you.

Can I find flights from South Carolina to Prague with flexible booking policies on momondo?

Flights from South Carolina to Prague with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from South Carolina to Prague?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Prague.

I’m not ready to book a flight from South Carolina to Prague right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Prague flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Prague trip

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