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Cheap flights from Santiago to Santa Cruz de la Sierra from $214

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santa Cruz de la Sierra departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
8:50 pm - 4:35 am
SCL
-
VVI
8h 45m1 stop
LATAM Airlines Logo
10:43 am - 2:45 pm
VVI
-
SCL
3h 02mnonstop
$430LATAM Airlines
Wed, Feb 11 - Sun, Feb 15
LATAM Airlines Logo
4:33 am - 6:40 am
SCL
-
VVI
3h 07mnonstop
LATAM Airlines Logo
10:43 am - 2:45 pm
VVI
-
SCL
3h 02mnonstop
$472LATAM Airlines
Tue, Feb 10 - Sun, Feb 15
LATAM Airlines Logo
3:45 pm - 4:35 am
SCL
-
VVI
13h 50m2 stops
LATAM Airlines Logo
10:43 am - 2:45 pm
VVI
-
SCL
3h 02mnonstop
$502LATAM Airlines
Wed, Feb 11 - Sun, Feb 15
Multiple Airlines Logo
6:30 pm - 8:10 am
SCL
-
VVI
14h 40m2 stops
Multiple Airlines Logo
11:15 am - 3:17 pm
VVI
-
SCL
3h 02mnonstop
$537Multiple Airlines
Mon, Jan 19 - Sat, Jan 24
Multiple Airlines Logo
4:50 am - 5:00 pm
SCL
-
VVI
13h 10m1 stop
Multiple Airlines Logo
8:00 am - 12:15 pm
VVI
-
SCL
3h 15mnonstop
$549Multiple Airlines
Thu, Feb 12 - Mon, Feb 16
Multiple Airlines Logo
3:00 pm - 8:10 am
SCL
-
VVI
18h 10m2 stops
Multiple Airlines Logo
6:55 pm - 3:30 pm
VVI
-
SCL
19h 35m1 stop
$603Multiple Airlines
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
6:32 am - 10:28 am
SCL
-
VVI
4h 56mnonstop
Multiple Airlines Logo
9:50 pm - 5:30 pm
VVI
-
SCL
18h 40m2 stops
$604Multiple Airlines
Sat, Jan 3 - Sat, Jan 10
Multiple Airlines Logo
1:35 am - 4:30 am
SCL
-
VVI
27h 55m2 stops
Multiple Airlines Logo
8:00 am - 12:15 pm
VVI
-
SCL
3h 15mnonstop
$624Multiple Airlines
Thu, Feb 12 - Mon, Feb 16
LATAM Airlines Logo
6:32 am - 10:28 am
SCL
-
VVI
4h 56mnonstop
LATAM Airlines Logo
5:25 am - 5:55 pm
VVI
-
SCL
11h 30m1 stop
$642LATAM Airlines
Sat, Dec 20 - Sat, Jan 3
Multiple Airlines Logo
6:30 pm - 8:10 am
SCL
-
VVI
14h 40m2 stops
Multiple Airlines Logo
5:25 am - 5:25 pm
VVI
-
SCL
11h 00m1 stop
$648Multiple Airlines
Mon, Jan 19 - Sat, Jan 24

LATAM Airlines flights from Santiago to Santa Cruz de la Sierra

Our best LATAM Airlines deals on Santiago to Santa Cruz de la Sierra flight tickets
LATAM Airlines
Feb 11
SCL8:50 pmSantiago Arturo Merino Benitez
8h 45m
1 stop
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Feb 15
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL2:45 pmSantiago Arturo Merino Benitez
$430
Find similar
LATAM Airlines
Feb 10
SCL4:33 amSantiago Arturo Merino Benitez
3h 07m
VVI6:40 amSanta Cruz de la Sierra Viru Viru Intl
Feb 15
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL2:45 pmSantiago Arturo Merino Benitez
$472
Find similar
LATAM Airlines
Feb 11
SCL3:45 pmSantiago Arturo Merino Benitez
13h 50m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Feb 15
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL2:45 pmSantiago Arturo Merino Benitez
$502
Find similar

BoA flights from Santiago to Santa Cruz de la Sierra

Our best BoA deals on Santiago to Santa Cruz de la Sierra flight tickets
BoA
Jan 19
SCL1:10 pmSantiago Arturo Merino Benitez
3h 15m
VVI3:25 pmSanta Cruz de la Sierra Viru Viru Intl
Jan 24
VVI8:00 amSanta Cruz de la Sierra Viru Viru Intl
3h 15m
SCL12:15 pmSantiago Arturo Merino Benitez
$727
Find similar
BoA
Jan 3
SCL1:10 pmSantiago Arturo Merino Benitez
3h 15m
VVI3:25 pmSanta Cruz de la Sierra Viru Viru Intl
Jan 10
VVI8:00 amSanta Cruz de la Sierra Viru Viru Intl
3h 15m
SCL12:15 pmSantiago Arturo Merino Benitez
$939
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Wed 2/11

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 2/15

10:43 am-2:45 pm

Nonstop3h 02m

$430

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Tue 2/10

4:33 am-6:40 am

Nonstop3h 07m

Santa Cruz de la Sierra Viru Viru Intl

Sun 2/15

10:43 am-2:45 pm

Nonstop3h 02m

$472

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Wed 2/11

3:45 pm-4:35 am

2 stops13h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sun 2/15

10:43 am-2:45 pm

Nonstop3h 02m

$502

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 1/19

6:30 pm-8:10 am

2 stops14h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

11:15 am-3:17 pm

Nonstop3h 02m

$537

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 2/12

4:50 am-5:00 pm

1 stop13h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/16

8:00 am-12:15 pm

Nonstop3h 15m

$549

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Fri 2/13

3:00 pm-8:10 am

2 stops18h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/16

6:55 pm-3:30 pm

1 stop19h 35m

$603

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 1/3

6:32 am-10:28 am

Nonstop4h 56m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/10

9:50 pm-5:30 pm

2 stops18h 40m

$604

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 2/12

1:35 am-4:30 am

2 stops27h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/16

8:00 am-12:15 pm

Nonstop3h 15m

$624

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 12/20

6:32 am-10:28 am

Nonstop4h 56m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/3

5:25 am-5:55 pm

1 stop11h 30m

$642

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 1/19

6:30 pm-8:10 am

2 stops14h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

5:25 am-5:25 pm

1 stop11h 00m

$648

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Santiago to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Santa Cruz de la Sierra?

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from Santiago is in October. Flight prices, which tend to average around $379, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in October, then you should wait until August to fly from Santiago, when ticket prices are also cheap, with an average price of $386.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the afternoon is the cheapest time of day to fly from Santiago to Santa Cruz de la Sierra when you can find flight prices for as low as $475. Flying to Santa Cruz de la Sierra in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the evening are often more expensive with an average ticket price of $524.

What is the cheapest Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flight route?

Fly from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl for the best Santiago Arturo Merino Benitez - Santa Cruz de la Sierra Viru Viru Intl flight prices

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around $406 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from Santiago for as low as $348 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flights?

There is only 1 cabin class available to choose from on Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Santa Cruz de la Sierra flights?

No. A direct flight is the cheapest option for a flight between Santiago to Santa Cruz de la Sierra.

How have Santiago to Santa Cruz de la Sierra flight prices changed over time?

As of December 2025, prices for Santiago to Santa Cruz de la Sierra flights are approximately 19% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santa Cruz de la Sierra (SCL to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santa Cruz de la Sierra

Fastest flight time

4h 56m

Direct flights

Tue, Wed and Sun

Airports in Santa Cruz de la Sierra

1 airport
The fastest flight from Santiago to Santa Cruz de la Sierra takes 4h 56m
Direct flights go from Santiago to Santa Cruz de la Sierra on Tuesday, Wednesday and Sunday. There are no airlines offering direct flights.
There is 1 airport near Santa Cruz de la Sierra: Santa Cruz de la Sierra Viru Viru Intl (VVI)
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl by plane?

    There are 1175.2 mi between Santiago Arturo Merino Benitez and Santa Cruz de la Sierra Viru Viru Intl. 3h 07m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Santiago to Santa Cruz de la Sierra?

  • What is the most popular airline from Santiago to Santa Cruz de la Sierra?

Best airlines flying from Santiago to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Santiago to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $248Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santa Cruz de la Sierra?

Finding the right flight to Santa Cruz de la Sierra from Santiago is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Cruz de la Sierra quick and easy, saving you time and money.

Can I find flights from Santiago to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Cruz de la Sierra from Santiago with this policy.

How can momondo help me find flights from Santiago to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from Santiago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santiago to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to Santa Cruz de la Sierra flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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