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Cheap flights from Santiago to Santa Cruz de la Sierra from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santa Cruz de la Sierra departing on 3/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
4:33 am - 6:40 am
SCL
-
VVI
3h 07mnonstop
LATAM Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$386LATAM Airlines
mar., feb. 24 - mié., mar. 4
LATAM Airlines Logo
6:30 pm - 4:35 am
SCL
-
VVI
11h 05m
1 stop
LATAM Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$391LATAM Airlines
mié., feb. 25 - mié., mar. 4
LATAM Airlines Logo
8:50 pm - 4:35 am
SCL
-
VVI
8h 45m
1 stop
LATAM Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$393LATAM Airlines
lun., mar. 2 - mié., mar. 11
Multiple Airlines Logo
8:50 pm - 5:45 pm
SCL
-
VVI
21h 55m
2 stops
Multiple Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$408Multiple Airlines
lun., mar. 23 - mié., mar. 25
LATAM Airlines Logo
3:45 pm - 4:35 am
SCL
-
VVI
37h 50m
2 stops
LATAM Airlines Logo
10:41 am - 2:45 pm
VVI
-
SCL
3h 04mnonstop
$410LATAM Airlines
vie., mar. 6 - dom., mar. 8
Multiple Airlines Logo
6:30 pm - 10:20 am
SCL
-
VVI
16h 50m
2 stops
Multiple Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$415Multiple Airlines
mié., feb. 25 - mié., mar. 4
LATAM Airlines Logo
3:45 pm - 4:35 am
SCL
-
VVI
37h 50m
2 stops
LATAM Airlines Logo
10:41 am - 2:45 pm
VVI
-
SCL
3h 04mnonstop
$420LATAM Airlines
vie., mar. 6 - dom., mar. 8
LATAM Airlines Logo
8:50 pm - 4:35 am
SCL
-
VVI
8h 45m
1 stop
LATAM Airlines Logo
5:25 am - 3:30 pm
VVI
-
SCL
9h 05m
1 stop
$423LATAM Airlines
lun., mar. 23 - vie., mar. 27
LATAM Airlines Logo
8:50 pm - 4:35 am
SCL
-
VVI
8h 45m
1 stop
LATAM Airlines Logo
10:41 am - 2:45 pm
VVI
-
SCL
3h 04mnonstop
$428LATAM Airlines
vie., mar. 6 - dom., mar. 8
LATAM Airlines Logo
4:35 am - 4:35 am
SCL
-
VVI
25h 00m
1 stop
LATAM Airlines Logo
7:26 am - 11:27 am
VVI
-
SCL
3h 01mnonstop
$433LATAM Airlines
lun., mar. 23 - mié., mar. 25

LATAM Airlines flights from Santiago to Santa Cruz de la Sierra

Our best LATAM Airlines deals on Santiago to Santa Cruz de la Sierra flight tickets
LATAM Airlines
Feb 24
SCL4:33 amSantiago Arturo Merino Benitez
3h 07m
VVI6:40 amSanta Cruz de la Sierra Viru Viru Intl
Mar 4
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 01m
SCL11:27 amSantiago Arturo Merino Benitez
$386
LATAM Airlines
Feb 25
SCL6:30 pmSantiago Arturo Merino Benitez
11h 05m
1 stop
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 4
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 01m
SCL11:27 amSantiago Arturo Merino Benitez
$391
LATAM Airlines
Mar 2
SCL8:50 pmSantiago Arturo Merino Benitez
8h 45m
1 stop
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 11
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 01m
SCL11:27 amSantiago Arturo Merino Benitez
$393

Avianca flights from Santiago to Santa Cruz de la Sierra

Our best Avianca deals on Santiago to Santa Cruz de la Sierra flight tickets
Avianca
Mar 3
SCL4:25 pmSantiago Arturo Merino Benitez
11h 10m
1 stop
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 10
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
19h 50m
1 stop
SCL12:30 amSantiago Arturo Merino Benitez
$450
Avianca
Mar 1
SCL1:35 amSantiago Arturo Merino Benitez
26h 00m
1 stop
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 12
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
19h 50m
1 stop
SCL12:30 amSantiago Arturo Merino Benitez
$462
Avianca
Mar 2
SCL7:25 amSantiago Arturo Merino Benitez
20h 10m
1 stop
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 11
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
19h 50m
1 stop
SCL12:30 amSantiago Arturo Merino Benitez
$601

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

mar. 2/24

4:33 am-6:40 am

Nonstop3h 07m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/4

7:26 am-11:27 am

Nonstop3h 01m

$386

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

mié. 2/25

6:30 pm-4:35 am

1 stop11h 05m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/4

7:26 am-11:27 am

Nonstop3h 01m

$391

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

lun. 3/2

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/11

7:26 am-11:27 am

Nonstop3h 01m

$393

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

lun. 3/23

8:50 pm-5:45 pm

2 stops21h 55m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/25

7:26 am-11:27 am

Nonstop3h 01m

$408

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

vie. 3/6

3:45 pm-4:35 am

2 stops37h 50m

Santa Cruz de la Sierra Viru Viru Intl

dom. 3/8

10:41 am-2:45 pm

Nonstop3h 04m

$410

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

mié. 2/25

6:30 pm-10:20 am

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/4

7:26 am-11:27 am

Nonstop3h 01m

$415

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

vie. 3/6

3:45 pm-4:35 am

2 stops37h 50m

Santa Cruz de la Sierra Viru Viru Intl

dom. 3/8

10:41 am-2:45 pm

Nonstop3h 04m

$420

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

lun. 3/23

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

vie. 3/27

5:25 am-3:30 pm

1 stop9h 05m

$423

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

vie. 3/6

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

dom. 3/8

10:41 am-2:45 pm

Nonstop3h 04m

$428

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

lun. 3/23

4:35 am-4:35 am

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

mié. 3/25

7:26 am-11:27 am

Nonstop3h 01m

$433

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Santiago to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Santa Cruz de la Sierra?

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from Santiago is in October. Flight prices, which tend to average around $379, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in October, then you should wait until August to fly from Santiago, when ticket prices are also cheap, with an average price of $386.

What is the cheapest Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flight route?

Fly from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl for the best Santiago Arturo Merino Benitez - Santa Cruz de la Sierra Viru Viru Intl flight prices

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around $415 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from Santiago for as low as $348 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flights?

There is only 1 cabin class available to choose from on Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Santa Cruz de la Sierra flights?

You could potentially save up to 31% on your flight if you consider stops on a Santiago to Santa Cruz de la Sierra flight.

How have Santiago to Santa Cruz de la Sierra flight prices changed over time?

As of January 2026, prices for Santiago to Santa Cruz de la Sierra flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santa Cruz de la Sierra (SCL to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santa Cruz de la Sierra

Fastest flight time

9h 05m

Direct flights

Tue and Wed

Airports in Santa Cruz de la Sierra

1 airport
The fastest flight from Santiago to Santa Cruz de la Sierra takes 9h 05m
Direct flights go from Santiago to Santa Cruz de la Sierra on Tuesday and Wednesday. There are no airlines offering direct flights.
There is 1 airport in Santa Cruz de la Sierra. From Santiago there are direct flights to Santa Cruz de la Sierra Viru Viru Intl (VVI).
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl by plane?

    There are 1175.2 mi between Santiago Arturo Merino Benitez and Santa Cruz de la Sierra Viru Viru Intl. 9h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Santiago to Santa Cruz de la Sierra?

  • What is the most popular airline from Santiago to Santa Cruz de la Sierra?

Best airlines flying from Santiago to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Santiago to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $248Free CancellationRating
7.5
1,917 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santiago to Santa Cruz de la Sierra

    LATAM Airlines is one of the most popular airlines flying from Santiago to Santa Cruz de la Sierra, operating 1 flight/week on average for this route. A good LATAM Airlines flight deal for Santiago to Santa Cruz de la Sierra starts from $248 round-trip, up to an average price of $416. Our users have rated LATAM Airlines at 7.5/10.

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santa Cruz de la Sierra?

Finding the right flight to Santa Cruz de la Sierra from Santiago is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Cruz de la Sierra quick and easy, saving you time and money.

Can I find flights from Santiago to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Cruz de la Sierra from Santiago with this policy.

How can momondo help me find flights from Santiago to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from Santiago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santiago to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to Santa Cruz de la Sierra flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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