Cheap flights from Santiago to Madrid from $325

The month of March is, on average, the cheapest month to fly to Madrid from Santiago, with most prices found around $757. If you don’t want to visit Madrid in March, then you should wait until November to fly from Santiago, when ticket prices are also cheap, with an average price of $808.

The cheapest day to depart on your flight to Madrid is on a Sunday when prices can be found for as low as $982. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Friday is $1,302.

Flying to Madrid from Santiago in the morning is the least expensive time of day to depart. momondo users have found prices as low as $1,061 when looking at flights departing in the morning. Flights to Madrid are more costly in the afternoon, with an average ticket price of $1,183. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Santiago Arturo Merino Benitez to Madrid Barajas for the best Santiago Arturo Merino Benitez - Madrid Barajas flight prices

You are more likely to see cheaper flights to Madrid from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $988 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Santiago for as low as $785 on momondo.

There are 3 cabin classes available to choose from on Santiago to Madrid flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Santiago to Madrid.

As of August 2026, prices for Santiago to Madrid flights are approximately 10% cheaper when compared to flights at the same time last year.

KLM and Iberia are the most popular carriers operating from Santiago Arturo Merino Benitez to Madrid Barajas

Iberia, LATAM Airlines and Avianca are the top three most popular airlines that fly to Madrid from Santiago according to our data. Iberia is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Madrid. Keep in mind that there are 4 different airlines that fly to Madrid on a routine basis, so you have a few additional options to choose from.

Historically, on average around 10% of flights between Santiago and Madrid have experienced a delay on any given week. The average delay length over the past 12 months has been 146 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

Bogotá (BOG) was the most common stop: 89% of momondo users choosing 1-stop flights on this route connected there.

Flights via Bogotá (BOG) offer the lowest average round-trip price of $843.

Flights connecting via Paris (CDG) have the shortest average one-way travel time: 17h 00m.

Paris (CDG) has the shortest average layover time for this route: 1h 00m.

As of August 2026, there are 12 flights per day flying from Santiago to Madrid. The most common time of day flights depart is 10:00AM, with 66% of flights taking off at noon.

As of August 2026, there are 84 flights per week flying from Santiago to Madrid. The most common day of the week flights depart is Sun, with 18% of flights taking off on this day.