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Cheap flights from Santiago to Cusco from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Cusco departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Cusco

Cheap round-trip flights

Sky Airline Logo
11:05 pm - 6:45 amSCL-CUZ
9h 40m1 stop
Sky Airline Logo
7:30 am - 10:15 pmCUZ-SCL
12h 45m1 stop
$260Sky Airline
Find Deal
Mon, Mar 2 - Mon, Mar 9
Sky Airline Logo
1:35 am - 7:45 pmSCL-CUZ
20h 10m2 stops
Sky Airline Logo
11:40 am - 10:15 pmCUZ-SCL
8h 35m1 stop
$264Sky Airline
Find Deal
Tue, Dec 9 - Mon, Dec 15
Sky Airline Logo
1:30 am - 5:50 pmSCL-CUZ
18h 20m2 stops
Sky Airline Logo
11:40 am - 10:15 pmCUZ-SCL
8h 35m1 stop
$265Sky Airline
Find Deal
Wed, Nov 19 - Wed, Dec 3
Sky Airline Logo
1:30 am - 4:05 pmSCL-CUZ
16h 35m2 stops
Sky Airline Logo
8:45 pm - 12:15 pmCUZ-SCL
13h 30m2 stops
$266Sky Airline
Find Deal
Mon, Mar 2 - Tue, Mar 10
Multiple Airlines Logo
1:45 am - 7:55 pmSCL-CUZ
20h 10m2 stops
Multiple Airlines Logo
4:42 pm - 5:01 amCUZ-SCL
10h 19m1 stop
$273Multiple Airlines
Find Deal
Mon, Oct 13 - Tue, Oct 21
LATAM Airlines Logo
4:35 am - 11:10 amSCL-CUZ
8h 35m1 stop
LATAM Airlines Logo
6:50 am - 3:30 pmCUZ-SCL
6h 40m1 stop
$279LATAM Airlines
Find Deal
Sun, Mar 1 - Mon, Mar 9
LATAM Airlines Logo
3:45 pm - 5:15 pmSCL-CUZ
3h 30mnonstop
LATAM Airlines Logo
7:35 am - 5:20 pmCUZ-SCL
7h 45m1 stop
$282LATAM Airlines
Find Deal
Mon, Mar 2 - Mon, Mar 9
JetSMART Logo
5:59 am - 12:56 pmSCL-CUZ
8h 57m1 stop
JetSMART Logo
4:00 pm - 5:14 amCUZ-SCL
11h 14m1 stop
$283JetSMART
Find Deal
Thu, Dec 4 - Tue, Dec 9
Multiple Airlines Logo
1:35 am - 7:55 pmSCL-CUZ
20h 20m2 stops
Multiple Airlines Logo
12:05 am - 3:30 pmCUZ-SCL
13h 25m1 stop
$289Multiple Airlines
Find Deal
Tue, Oct 21 - Mon, Oct 27
JetSMART Logo
5:55 am - 3:24 pmSCL-CUZ
11h 29m1 stop
JetSMART Logo
4:00 pm - 5:14 amCUZ-SCL
11h 14m1 stop
$292JetSMART
Find Deal
Sat, Dec 6 - Tue, Dec 9

LATAM Airlines flights from Santiago to Cusco

Our best LATAM Airlines deals on Santiago to Cusco flight tickets
LATAM Airlines
Mar 1
SCL4:35 amSantiago Arturo Merino Benitez
8h 35m
1 stop
CUZ11:10 amCusco Velazco Astete
Mar 9
CUZ6:50 amCusco Velazco Astete
6h 40m
1 stop
SCL3:30 pmSantiago Arturo Merino Benitez
$279
Find similar
LATAM Airlines
Mar 2
SCL3:45 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:15 pmCusco Velazco Astete
Mar 9
CUZ7:35 amCusco Velazco Astete
7h 45m
1 stop
SCL5:20 pmSantiago Arturo Merino Benitez
$282
Find similar
LATAM Airlines
Mar 1
SCL4:35 amSantiago Arturo Merino Benitez
8h 35m
1 stop
CUZ11:10 amCusco Velazco Astete
Mar 9
CUZ9:30 amCusco Velazco Astete
3h 15m
SCL2:45 pmSantiago Arturo Merino Benitez
$298
Find similar

Sky Airline flights from Santiago to Cusco

Our best Sky Airline deals on Santiago to Cusco flight tickets
Sky Airline
Mar 2
SCL11:05 pmSantiago Arturo Merino Benitez
9h 40m
1 stop
CUZ6:45 amCusco Velazco Astete
Mar 9
CUZ7:30 amCusco Velazco Astete
12h 45m
1 stop
SCL10:15 pmSantiago Arturo Merino Benitez
$260
Find similar
Sky Airline
Dec 9
SCL1:35 amSantiago Arturo Merino Benitez
20h 10m
2 stops
CUZ7:45 pmCusco Velazco Astete
Dec 15
CUZ11:40 amCusco Velazco Astete
8h 35m
1 stop
SCL10:15 pmSantiago Arturo Merino Benitez
$264
Find similar
Sky Airline
Sep 26
SCL1:35 amSantiago Arturo Merino Benitez
21h 20m
2 stops
CUZ8:55 pmCusco Velazco Astete
Oct 4
CUZ9:30 pmCusco Velazco Astete
15h 15m
1 stop
SCL2:45 pmSantiago Arturo Merino Benitez
$265
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 3/2

11:05 pm-6:45 am

1 stop9h 40m

Cusco Velazco Astete

Mon 3/9

7:30 am-10:15 pm

1 stop12h 45m

$260

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 12/9

1:35 am-7:45 pm

2 stops20h 10m

Cusco Velazco Astete

Mon 12/15

11:40 am-10:15 pm

1 stop8h 35m

$264

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 11/19

1:30 am-5:50 pm

2 stops18h 20m

Cusco Velazco Astete

Wed 12/3

11:40 am-10:15 pm

1 stop8h 35m

$265

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 3/2

1:30 am-4:05 pm

2 stops16h 35m

Cusco Velazco Astete

Tue 3/10

8:45 pm-12:15 pm

2 stops13h 30m

$266

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 10/13

1:45 am-7:55 pm

2 stops20h 10m

Cusco Velazco Astete

Tue 10/21

4:42 pm-5:01 am

1 stop10h 19m

$273

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 3/1

4:35 am-11:10 am

1 stop8h 35m

Cusco Velazco Astete

Mon 3/9

6:50 am-3:30 pm

1 stop6h 40m

$279

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 3/2

3:45 pm-5:15 pm

Nonstop3h 30m

Cusco Velazco Astete

Mon 3/9

7:35 am-5:20 pm

1 stop7h 45m

$282

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 12/4

5:59 am-12:56 pm

1 stop8h 57m

Cusco Velazco Astete

Tue 12/9

4:00 pm-5:14 am

1 stop11h 14m

$283

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 10/21

1:35 am-7:55 pm

2 stops20h 20m

Cusco Velazco Astete

Mon 10/27

12:05 am-3:30 pm

1 stop13h 25m

$289

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 12/6

5:55 am-3:24 pm

1 stop11h 29m

Cusco Velazco Astete

Tue 12/9

4:00 pm-5:14 am

1 stop11h 14m

$292

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Santiago to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Cusco?

What is the cheapest month to fly to Cusco?

In general, March is the cheapest month to fly from Santiago to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $247. If you aren’t able to travel to Cusco during the month of March, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $254.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart from Santiago to Cusco is on a Saturday when prices can be found for as low as $288. The most expensive day to fly to Cusco is Friday, with ticket prices averaging around $455.

What is the cheapest time of day to depart on your flight to Cusco?

According to our data, the cheapest time of day to fly to Cusco is in the morning. momondo users have found flights departing from Santiago to Cusco in the morning for as low as $302. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Cusco is in the evening when prices are around $399.

What is the cheapest Santiago Arturo Merino Benitez to Cusco Velazco Astete flight route?

Fly from Santiago Arturo Merino Benitez to Cusco Velazco Astete for the best Santiago Arturo Merino Benitez - Cusco Velazco Astete flight prices

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $276 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Santiago for as low as $245 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Cusco flights?

You could potentially save up to 79% on your flight if you consider stops on a Santiago to Cusco flight.

How have Santiago to Cusco flight prices changed over time?

As of September 2025, prices for Santiago to Cusco flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Cusco (SCL to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Cusco

Best Price Found

$150

Fastest flight time

3h 30m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun

Airports in Cusco

1 airport
The best one-way flight to Cusco from Santiago in the past 72 hours is $150. The best round-trip flight deal from Santiago to Cusco found on momondo in the last 72 hours is $159.
The fastest flight from Santiago to Cusco takes 3h 30m
Direct flights go from Santiago to Cusco on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is LATAM Airlines.
There is 1 airport near Cusco: Cusco Velazco Astete (CUZ)
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Cusco Velazco Astete by plane?

    Cusco Velazco Astete is 1377.5 mi away from Santiago Arturo Merino Benitez. By plane, this route typically takes 3h 30m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The necessary travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Cusco?

  • What is the most popular airline from Santiago to Cusco?

Best airlines flying from Santiago to Cusco

Compare and see reviews for airlines that fly from Santiago to Cusco with momondo
Airline
Rating
Free Cancellation
Price
Sky AirlinePriceFrom $192Free CancellationRating
6.5
116 reviews
Search Sky Airline flights
LATAM AirlinesPriceFrom $217Free CancellationRating
7.5
1,849 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santiago to Cusco

    The lowest priced LATAM Airlines flight from Santiago to Cusco from the last 72 hours was $217. Generally, LATAM Airlines has 7 flights on this route every week with an average price of $328. LATAM Airlines is rated 7.5/10 by our users.

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Cusco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Cusco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Cusco with flexible booking policies on momondo?

momondo does allow users to show only those flights to Cusco from Santiago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago to Cusco?

Once all potential Santiago to Cusco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santiago to Cusco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Cusco from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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