Cheap flights from Santiago to Cusco from $102

In general, March is the cheapest month to fly from Santiago to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $275. If you aren’t able to travel to Cusco during the month of March, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $285.

The cheapest day to depart from Santiago to Cusco is on a Monday when prices can be found for as low as $335. The most expensive day to fly to Cusco is Friday, with ticket prices averaging around $808.

According to our data, the cheapest time of day to fly to Cusco is in the morning. momondo users have found flights departing from Santiago to Cusco in the morning for as low as $340. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Cusco is in the evening when prices are around $622.

Fly from Santiago Arturo Merino Benitez to Cusco Velazco Astete for the best Santiago Arturo Merino Benitez - Cusco Velazco Astete flight prices

You are more likely to see cheaper flights to Cusco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $306 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Santiago for as low as $267 on momondo.

There are 2 cabin classes available to choose from on Santiago to Cusco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Santiago to Cusco.

As of November 2026, prices for Santiago to Cusco flights are approximately 11% more expensive when compared to flights at the same time last year.

Historically, on average around 16% of flights between Santiago and Cusco have experienced a delay on any given week. The average delay length over the past 12 months has been 110 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 16% of their flights experiencing any sort of delay.