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Cheap flights from Santiago to Cusco from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Cusco departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santiago to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Sky Airline Logo
8:20 pm - 7:45 am
SCL
-
CUZ
12h 25m
1 stop
Sky Airline Logo
9:40 pm - 1:30 pm
CUZ
-
SCL
14h 50m
1 stop
$242Sky Airline
Mon, Apr 6 - Sun, Apr 12
LATAM Airlines Logo
10:25 pm - 6:15 am
SCL
-
CUZ
9h 50m
1 stop
LATAM Airlines Logo
5:00 am - 3:00 pm
CUZ
-
SCL
8h 00m
1 stop
$246LATAM Airlines
Mon, Mar 23 - Tue, Mar 31
LATAM Airlines Logo
2:40 pm - 5:10 pm
SCL
-
CUZ
3h 30mnonstop
LATAM Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
$247LATAM Airlines
Mon, Apr 6 - Sat, Apr 11
Sky Airline Logo
1:35 am - 5:55 pm
SCL
-
CUZ
18h 20m
2 stops
Sky Airline Logo
9:45 pm - 10:15 pm
CUZ
-
SCL
22h 30m
1 stop
$248Sky Airline
Thu, Mar 12 - Fri, Mar 20
LATAM Airlines Logo
3:45 pm - 5:15 pm
SCL
-
CUZ
3h 30mnonstop
LATAM Airlines Logo
9:30 am - 2:45 pm
CUZ
-
SCL
3h 15mnonstop
$250LATAM Airlines
Fri, Mar 13 - Fri, Mar 20
LATAM Airlines Logo
4:50 pm - 11:25 pm
SCL
-
CUZ
7h 35m
1 stop
LATAM Airlines Logo
2:40 pm - 7:00 pm
CUZ
-
SCL
3h 20mnonstop
$252LATAM Airlines
Mon, Apr 6 - Sun, Apr 12
Sky Airline Logo
5:50 am - 6:25 am
SCL
-
CUZ
26h 35m
1 stop
Sky Airline Logo
9:45 pm - 2:40 pm
CUZ
-
SCL
14h 55m
1 stop
$254Sky Airline
Fri, Mar 13 - Fri, Mar 20
JetSMART Logo
4:56 am - 11:00 am
SCL
-
CUZ
7h 04m
1 stop
JetSMART Logo
7:55 am - 5:11 pm
CUZ
-
SCL
8h 16m
1 stop
$255JetSMART
Fri, May 29 - Sat, Jun 6
JetSMART Logo
4:56 am - 11:05 am
SCL
-
CUZ
7h 09m
1 stop
JetSMART Logo
8:25 am - 5:11 pm
CUZ
-
SCL
7h 46m
1 stop
$256JetSMART
Mon, Jun 22 - Fri, Jun 26
LATAM Airlines Logo
10:25 pm - 6:55 am
SCL
-
CUZ
10h 30m
1 stop
LATAM Airlines Logo
9:30 am - 2:50 pm
CUZ
-
SCL
3h 20mnonstop
$257LATAM Airlines
Mon, Mar 23 - Tue, Mar 31

LATAM Airlines flights from Santiago to Cusco

Our best LATAM Airlines deals on Santiago to Cusco flight tickets
LATAM Airlines
Mar 23
SCL10:25 pmSantiago Arturo Merino Benitez
9h 50m
1 stop
CUZ6:15 amCusco Velazco Astete
Mar 31
CUZ5:00 amCusco Velazco Astete
8h 00m
1 stop
SCL3:00 pmSantiago Arturo Merino Benitez
$246
LATAM Airlines
Apr 6
SCL2:40 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:10 pmCusco Velazco Astete
Apr 11
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
$247
LATAM Airlines
Mar 13
SCL3:45 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:15 pmCusco Velazco Astete
Mar 20
CUZ9:30 amCusco Velazco Astete
3h 15m
SCL2:45 pmSantiago Arturo Merino Benitez
$250

JetSMART flights from Santiago to Cusco

Our best JetSMART deals on Santiago to Cusco flight tickets
JetSMART
May 29
SCL4:56 amSantiago Arturo Merino Benitez
7h 04m
1 stop
CUZ11:00 amCusco Velazco Astete
Jun 6
CUZ7:55 amCusco Velazco Astete
8h 16m
1 stop
SCL5:11 pmSantiago Arturo Merino Benitez
$255
JetSMART
Jun 22
SCL4:56 amSantiago Arturo Merino Benitez
7h 09m
1 stop
CUZ11:05 amCusco Velazco Astete
Jun 26
CUZ8:25 amCusco Velazco Astete
7h 46m
1 stop
SCL5:11 pmSantiago Arturo Merino Benitez
$256
JetSMART
Jun 26
SCL3:11 pmSantiago Arturo Merino Benitez
7h 39m
1 stop
CUZ9:50 pmCusco Velazco Astete
Jul 3
CUZ4:57 pmCusco Velazco Astete
10h 17m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
$262

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 4/6

8:20 pm-7:45 am

1 stop12h 25m

Cusco Velazco Astete

Sun 4/12

9:40 pm-1:30 pm

1 stop14h 50m

$242

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 3/23

10:25 pm-6:15 am

1 stop9h 50m

Cusco Velazco Astete

Tue 3/31

5:00 am-3:00 pm

1 stop8h 00m

$246

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 4/6

2:40 pm-5:10 pm

Nonstop3h 30m

Cusco Velazco Astete

Sat 4/11

9:30 am-1:50 pm

Nonstop3h 20m

$247

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 3/12

1:35 am-5:55 pm

2 stops18h 20m

Cusco Velazco Astete

Fri 3/20

9:45 pm-10:15 pm

1 stop22h 30m

$248

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 3/13

3:45 pm-5:15 pm

Nonstop3h 30m

Cusco Velazco Astete

Fri 3/20

9:30 am-2:45 pm

Nonstop3h 15m

$250

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 4/6

4:50 pm-11:25 pm

1 stop7h 35m

Cusco Velazco Astete

Sun 4/12

2:40 pm-7:00 pm

Nonstop3h 20m

$252

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 3/13

5:50 am-6:25 am

1 stop26h 35m

Cusco Velazco Astete

Fri 3/20

9:45 pm-2:40 pm

1 stop14h 55m

$254

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 5/29

4:56 am-11:00 am

1 stop7h 04m

Cusco Velazco Astete

Sat 6/6

7:55 am-5:11 pm

1 stop8h 16m

$255

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 6/22

4:56 am-11:05 am

1 stop7h 09m

Cusco Velazco Astete

Fri 6/26

8:25 am-5:11 pm

1 stop7h 46m

$256

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 3/23

10:25 pm-6:55 am

1 stop10h 30m

Cusco Velazco Astete

Tue 3/31

9:30 am-2:50 pm

Nonstop3h 20m

$257

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Santiago to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Cusco?

What is the cheapest month to fly to Cusco?

In general, November is the cheapest month to fly from Santiago to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $255. If you aren’t able to travel to Cusco during the month of November, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $264.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart from Santiago to Cusco is on a Tuesday when prices can be found for as low as $288. The most expensive day to fly to Cusco is Wednesday, with ticket prices averaging around $569.

What is the cheapest time of day to depart on your flight to Cusco?

According to our data, the cheapest time of day to fly to Cusco is at noon. momondo users have found flights departing from Santiago to Cusco at noon for as low as $312. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Cusco is in the evening when prices are around $569.

What is the cheapest Santiago Arturo Merino Benitez to Cusco Velazco Astete flight route?

Fly from Santiago Arturo Merino Benitez to Cusco Velazco Astete for the best Santiago Arturo Merino Benitez - Cusco Velazco Astete flight prices

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $281 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Santiago for as low as $259 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Cusco flights?

No. A direct flight is the cheapest option for a flight between Santiago to Cusco.

How have Santiago to Cusco flight prices changed over time?

As of January 2026, prices for Santiago to Cusco flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Cusco (SCL to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Cusco

Best Price Found

$150

Fastest flight time

3h 30m

Direct flights

Every day

Airports in Cusco

1 airport
The best one-way flight to Cusco from Santiago in the past 72 hours is $150. The best round-trip flight deal from Santiago to Cusco found on momondo in the last 72 hours is $402.
The fastest flight from Santiago to Cusco takes 3h 30m
Direct flights go from Santiago to Cusco every day.
There is 1 airport in Cusco. From Santiago there are direct flights to Cusco Velazco Astete (CUZ).
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Cusco Velazco Astete by plane?

    Cusco Velazco Astete is 1377.5 mi away from Santiago Arturo Merino Benitez. By plane, this route typically takes 3h 30m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The necessary travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Cusco?

  • What is the most popular airline from Santiago to Cusco?

Best airlines flying from Santiago to Cusco

Compare and see reviews for airlines that fly from Santiago to Cusco with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $207Free CancellationRating
7.5
1,917 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santiago to Cusco

    The lowest priced LATAM Airlines flight from Santiago to Cusco from the last 72 hours was $207. Generally, LATAM Airlines has 7 flights on this route every week with an average price of $328. LATAM Airlines is rated 7.5/10 by our users.

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Cusco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Cusco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Cusco with flexible booking policies on momondo?

momondo does allow users to show only those flights to Cusco from Santiago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago to Cusco?

Once all potential Santiago to Cusco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santiago to Cusco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Cusco from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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