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Cheap flights from San Francisco to Panama City from $206

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Panama City departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Panama City

Cheap round-trip flights

Avianca Logo
12:05 am - 10:25 amSFO-PTY
8h 20m1 stop
Avianca Logo
3:25 am - 10:45 pmPTY-SFO
21h 20m2 stops
$489Avianca
Find Deal
lun., sep. 8 - lun., sep. 15
Avianca Logo
11:10 pm - 10:20 amSFO-PTY
8h 10m1 stop
Avianca Logo
3:35 pm - 9:50 pmPTY-SFO
9h 15m1 stop
$492Avianca
Find Deal
sáb., nov. 8 - vie., nov. 14
Avianca Logo
12:05 am - 9:10 pmSFO-PTY
19h 05m2 stops
Avianca Logo
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
$493Avianca
Find Deal
vie., oct. 3 - dom., oct. 12
Avianca Logo
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
Avianca Logo
2:55 am - 10:50 pmPTY-SFO
21h 55m2 stops
$494Avianca
Find Deal
jue., oct. 23 - sáb., oct. 25
Avianca Logo
1:35 am - 2:50 pmSFO-PTY
10h 15m1 stop
Avianca Logo
9:45 am - 9:50 pmPTY-SFO
15h 05m2 stops
$495Avianca
Find Deal
mar., ene. 20 - jue., ene. 22
Avianca Logo
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
Avianca Logo
3:20 am - 10:45 pmPTY-SFO
21h 25m2 stops
$499Avianca
Find Deal
dom., sep. 21 - sáb., sep. 27
Avianca Logo
1:20 pm - 2:00 pmSFO-PTY
21h 40m2 stops
Avianca Logo
9:45 am - 9:50 pmPTY-SFO
15h 05m2 stops
$501Avianca
Find Deal
sáb., nov. 29 - mar., dic. 9
Avianca Logo
2:20 pm - 4:30 pmSFO-PTY
24h 10m2 stops
Avianca Logo
2:55 pm - 1:00 pmPTY-SFO
24h 05m2 stops
$502Avianca
Find Deal
jue., oct. 23 - lun., oct. 27
Logo
7:10 pm - 10:25 amSFO-PTY
13h 15m2 stops
Logo
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
$572
Find Deal
mar., sep. 9 - mar., sep. 16
Copa Airlines Logo
12:42 am - 10:46 amSFO-PTY
7h 04mnonstop
Copa Airlines Logo
6:27 pm - 11:20 pmPTY-SFO
7h 53mnonstop
$637Copa Airlines
Find Deal
mar., ene. 20 - jue., ene. 22

Avianca flights from San Francisco to Panama City

Our best Avianca deals on San Francisco to Panama City flight tickets
Avianca
Sep 8
SFO12:05 amSan Francisco
8h 20m
1 stop
PTY10:25 amPanama City Tocumen Intl
Sep 15
PTY3:25 amPanama City Tocumen Intl
21h 20m
2 stops
SFO10:45 pmSan Francisco
$489
Find similar
Avianca
Nov 8
SFO11:10 pmSan Francisco
8h 10m
1 stop
PTY10:20 amPanama City Tocumen Intl
Nov 14
PTY3:35 pmPanama City Tocumen Intl
9h 15m
1 stop
SFO9:50 pmSan Francisco
$492
Find similar
Avianca
Oct 3
SFO12:05 amSan Francisco
19h 05m
2 stops
PTY9:10 pmPanama City Tocumen Intl
Oct 12
PTY3:40 pmPanama City Tocumen Intl
9h 05m
1 stop
SFO10:45 pmSan Francisco
$493
Find similar

Copa Airlines flights from San Francisco to Panama City

Our best Copa Airlines deals on San Francisco to Panama City flight tickets
Copa Airlines
Jan 20
SFO12:42 amSan Francisco
7h 04m
PTY10:46 amPanama City Tocumen Intl
Jan 22
PTY6:27 pmPanama City Tocumen Intl
7h 53m
SFO11:20 pmSan Francisco
$637
Find similar
Copa Airlines
Sep 2
SFO1:30 amSan Francisco
7h 11m
PTY10:41 amPanama City Tocumen Intl
Sep 22
PTY5:50 pmPanama City Tocumen Intl
7h 35m
SFO11:25 pmSan Francisco
$920
Find similar
Copa Airlines
Sep 2
SFO1:30 amSan Francisco
7h 11m
PTY10:41 amPanama City Tocumen Intl
Sep 5
PTY5:50 pmPanama City Tocumen Intl
7h 35m
SFO11:25 pmSan Francisco
$1,003
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 28, 2025.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

lun. 9/8

12:05 am-10:25 am

1 stop8h 20m

Panama City Tocumen Intl

lun. 9/15

3:25 am-10:45 pm

2 stops21h 20m

$489

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

sáb. 11/8

11:10 pm-10:20 am

1 stop8h 10m

Panama City Tocumen Intl

vie. 11/14

3:35 pm-9:50 pm

1 stop9h 15m

$492

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

vie. 10/3

12:05 am-9:10 pm

2 stops19h 05m

Panama City Tocumen Intl

dom. 10/12

3:40 pm-10:45 pm

1 stop9h 05m

$493

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

jue. 10/23

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

sáb. 10/25

2:55 am-10:50 pm

2 stops21h 55m

$494

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 1/20

1:35 am-2:50 pm

1 stop10h 15m

Panama City Tocumen Intl

jue. 1/22

9:45 am-9:50 pm

2 stops15h 05m

$495

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

dom. 9/21

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

sáb. 9/27

3:20 am-10:45 pm

2 stops21h 25m

$499

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

sáb. 11/29

1:20 pm-2:00 pm

2 stops21h 40m

Panama City Tocumen Intl

mar. 12/9

9:45 am-9:50 pm

2 stops15h 05m

$501

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

jue. 10/23

2:20 pm-4:30 pm

2 stops24h 10m

Panama City Tocumen Intl

lun. 10/27

2:55 pm-1:00 pm

2 stops24h 05m

$502

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 9/9

7:10 pm-10:25 am

2 stops13h 15m

Panama City Tocumen Intl

mar. 9/16

3:40 pm-10:45 pm

1 stop9h 05m

$572

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 1/20

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

jue. 1/22

6:27 pm-11:20 pm

Nonstop7h 53m

$637

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Francisco to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from San Francisco to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $593. If you’re not able to fly to Panama City in August, then May is your next best option. Flight prices from San Francisco to Panama City during May average around $608.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $620. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $756. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from San Francisco to Panama City during this time can be as low as $498. Try not to purchase tickets in the morning because they tend to be around $723. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Francisco to Panama City Tocumen Intl flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $662 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Francisco for as low as $603 on momondo.

What cabin class options are available on San Francisco to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on San Francisco to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama City flights?

You could potentially save up to 1% on your flight if you consider stops on a San Francisco to Panama City flight.

How have San Francisco to Panama City flight prices changed over time?

As of August 2025, prices for San Francisco to Panama City flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Panama City (SFO to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama City

Best Price Found

$235

Fastest flight time

7h 04m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Francisco in the past 72 hours is $235. The best round-trip flight deal from San Francisco to Panama City found on momondo in the last 72 hours is $492.
The fastest flight from San Francisco to Panama City takes 7h 04m
Direct flights go from San Francisco to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is San Francisco to Panama City Tocumen Intl by plane?

    The distance between San Francisco and Panama City Tocumen Intl is about 3322.3 mi. A reasonable flight in good conditions will take 7h 04m.

  • When did momondo last update prices for flights from San Francisco Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Francisco Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Francisco to Panama City?

  • What is the most popular airline from San Francisco to Panama City?

Best airlines flying from San Francisco to Panama City

Compare and see reviews for airlines that fly from San Francisco to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $387Free CancellationRating
7.9
7,977 reviews
Search Delta flights
AviancaPriceFrom $400Free CancellationRating
6.7
2,420 reviews
Search Avianca flights
Copa AirlinesPriceFrom $503Free CancellationRating
7.5
1,517 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $533Free CancellationRating
7.4
8,944 reviews
Search United Airlines flights
American AirlinesPriceFrom $544Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Copa Airlines Flights From San Francisco to Panama City

    Copa Airlines is one of the most popular airlines flying from San Francisco to Panama City, operating 12 flights/week on average for this route. A good Copa Airlines flight deal for San Francisco to Panama City starts from $503 round-trip, up to an average price of $647. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From San Francisco to Panama City

    $533 is the best United Airlines flight deal from San Francisco to Panama City found on momondo over the last 72 hours. The average United Airlines ticket price found was closer to $702, however, with flight time and availability significantly affecting the price. United Airlines (7.4/10 from 8,944 user reviews) flies into Panama City from San Francisco 14 times in an average week so prices can vary.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Panama City for you.

Can I find flights from San Francisco to Panama City with flexible booking policies on momondo?

Flights from San Francisco to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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