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Cheap flights from San Antonio to Santo Domingo from $242

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Santo Domingo departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Antonio to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 1:29 pm
SAT
-
SDQ
6h 29m
1 stop
Spirit Airlines Logo
2:24 pm - 11:49 pm
SDQ
-
SAT
10h 25m
1 stop
$470Spirit Airlines
Sat, May 2 - Sat, Jun 27
Spirit Airlines Logo
10:22 am - 1:29 pm
SAT
-
SDQ
26h 07m
1 stop
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
$481Spirit Airlines
Tue, Apr 14 - Sun, Apr 19
Spirit Airlines Logo
1:22 pm - 1:38 am
SAT
-
SDQ
11h 16m
2 stops
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
$487Spirit Airlines
Fri, Apr 10 - Thu, Apr 16
Spirit Airlines Logo
10:22 am - 1:15 pm
SAT
-
SDQ
25h 53m
1 stop
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
$498Spirit Airlines
Fri, Apr 10 - Thu, Apr 16
Multiple Airlines Logo
10:22 am - 4:29 pm
SAT
-
SDQ
29h 07m
2 stops
Multiple Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
$512Multiple Airlines
Tue, Apr 14 - Sun, Apr 19
Spirit Airlines Logo
1:22 pm - 1:29 pm
SAT
-
SDQ
23h 07m
3 stops
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
$523Spirit Airlines
Tue, Apr 14 - Sun, Apr 19
Spirit Airlines Logo
6:00 am - 1:19 pm
SAT
-
SDQ
6h 19m
1 stop
Spirit Airlines Logo
2:24 pm - 11:49 pm
SDQ
-
SAT
10h 25m
1 stop
$559Spirit Airlines
Mon, Aug 17 - Thu, Aug 27
American Airlines Logo
5:01 am - 3:24 pm
SAT
-
SDQ
9h 23m
1 stop
American Airlines Logo
8:00 am - 5:45 pm
SDQ
-
SAT
10h 45m
2 stops
$563American Airlines
Mon, Aug 3 - Thu, Oct 29
Spirit Airlines Logo
6:00 am - 1:19 pm
SAT
-
SDQ
6h 19m
1 stop
Spirit Airlines Logo
2:24 pm - 11:49 pm
SDQ
-
SAT
10h 25m
1 stop
$564Spirit Airlines
Thu, Jun 18 - Sun, Jun 21
Delta Logo
5:20 am - 1:12 pm
SAT
-
SDQ
6h 52m
1 stop
Delta Logo
2:49 pm - 10:31 pm
SDQ
-
SAT
8h 42m
1 stop
$571Delta
Mon, May 4 - Mon, May 11

Delta flights from San Antonio to Santo Domingo

Our best Delta deals on San Antonio to Santo Domingo flight tickets
Delta
May 4
SAT5:20 amSan Antonio
6h 52m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
May 11
SDQ2:49 pmSanto Domingo Las Americas
8h 42m
1 stop
SAT10:31 pmSan Antonio
$571
Delta
May 12
SAT5:25 amSan Antonio
6h 59m
1 stop
SDQ1:24 pmSanto Domingo Las Americas
May 16
SDQ2:48 pmSanto Domingo Las Americas
10h 56m
1 stop
SAT12:44 amSan Antonio
$572
Delta
May 4
SAT1:15 pmSan Antonio
10h 02m
1 stop
SDQ12:17 amSanto Domingo Las Americas
May 11
SDQ6:05 amSanto Domingo Las Americas
15h 23m
2 stops
SAT8:28 pmSan Antonio
$575

American Airlines flights from San Antonio to Santo Domingo

Our best American Airlines deals on San Antonio to Santo Domingo flight tickets
American Airlines
Aug 3
SAT5:01 amSan Antonio
9h 23m
1 stop
SDQ3:24 pmSanto Domingo Las Americas
Oct 29
SDQ8:00 amSanto Domingo Las Americas
10h 45m
2 stops
SAT5:45 pmSan Antonio
$563
American Airlines
Jun 1
SAT6:18 pmSan Antonio
17h 57m
1 stop
SDQ1:15 pmSanto Domingo Las Americas
Aug 22
SDQ4:25 pmSanto Domingo Las Americas
8h 00m
1 stop
SAT11:25 pmSan Antonio
$585
American Airlines
Jun 10
SAT6:15 pmSan Antonio
20h 03m
1 stop
SDQ3:18 pmSanto Domingo Las Americas
Sep 30
SDQ1:35 pmSanto Domingo Las Americas
9h 29m
2 stops
SAT10:04 pmSan Antonio
$589

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from San Antonio to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Sat 5/2

6:00 am-1:29 pm

1 stop6h 29m

Santo Domingo Las Americas

Sat 6/27

2:24 pm-11:49 pm

1 stop10h 25m

$470

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Tue 4/14

10:22 am-1:29 pm

1 stop26h 07m

Santo Domingo Las Americas

Sun 4/19

2:35 pm-11:51 pm

1 stop10h 16m

$481

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Fri 4/10

1:22 pm-1:38 am

2 stops11h 16m

Santo Domingo Las Americas

Thu 4/16

2:35 pm-11:51 pm

1 stop10h 16m

$487

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Fri 4/10

10:22 am-1:15 pm

1 stop25h 53m

Santo Domingo Las Americas

Thu 4/16

2:35 pm-11:51 pm

1 stop10h 16m

$498

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Tue 4/14

10:22 am-4:29 pm

2 stops29h 07m

Santo Domingo Las Americas

Sun 4/19

2:35 pm-11:51 pm

1 stop10h 16m

$512

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Tue 4/14

1:22 pm-1:29 pm

3 stops23h 07m

Santo Domingo Las Americas

Sun 4/19

2:35 pm-11:51 pm

1 stop10h 16m

$523

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Mon 8/17

6:00 am-1:19 pm

1 stop6h 19m

Santo Domingo Las Americas

Thu 8/27

2:24 pm-11:49 pm

1 stop10h 25m

$559

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Mon 8/3

5:01 am-3:24 pm

1 stop9h 23m

Santo Domingo Las Americas

Thu 10/29

8:00 am-5:45 pm

2 stops10h 45m

$563

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Thu 6/18

6:00 am-1:19 pm

1 stop6h 19m

Santo Domingo Las Americas

Sun 6/21

2:24 pm-11:49 pm

1 stop10h 25m

$564
Quickest round-trip

San AntonioSanto Domingo

SAT - SDQ

SATSDQ

San Antonio

Mon 5/4

5:20 am-1:12 pm

1 stop6h 52m

Santo Domingo Las Americas

Mon 5/11

2:49 pm-10:31 pm

1 stop8h 42m

$571

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Antonio to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Antonio and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in March, then you should wait until November to fly from San Antonio, when ticket prices are also cheap, with an average price of $459.

How have San Antonio to Santo Domingo flight prices changed over time?

When to book flights from San Antonio to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Santo Domingo (SAT to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Santo Domingo

Fastest flight time

6h 19m

Direct flights

None
The fastest flight from San Antonio to Santo Domingo takes 6h 19m
There are no direct flights from San Antonio to Santo Domingo. There are no popular flight routes from San Antonio to Santo Domingo.
Search flight deals

  • How far is San Antonio to Santo Domingo Las Americas by plane?

    A flight from San Antonio to Santo Domingo Las Americas will travel around 1947.2 mi. A reasonable flight in good conditions will take 6h 19m.

  • When did momondo last update prices for flights from San Antonio Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Antonio Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Antonio Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Antonio Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Santo Domingo?

Best airlines flying from San Antonio to Santo Domingo

Compare and see reviews for airlines that fly from San Antonio to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $211Free CancellationRating
7.9
8,366 reviews
Search Delta flights
Spirit AirlinesPriceFrom $329Free CancellationRating
6.3
8,570 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $426Free CancellationRating
7.1
11,545 reviews
Search American Airlines flights
JetBluePriceFrom $450Free CancellationRating
7.2
2,905 reviews
Search JetBlue flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Why should I use momondo to find a flight deal from San Antonio to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Antonio to Santo Domingo for you.

Can I find flights from San Antonio to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from San Antonio with this policy.

How can momondo help me find flights from San Antonio to Santo Domingo?

Once all potential San Antonio to Santo Domingo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Antonio to Santo Domingo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santo Domingo, momondo offers a useful price alert feature which will track prices for flights to Santo Domingo from San Antonio and alert you when they change.

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