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Cheap flights from San Antonio to Santiago from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Santiago departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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LATAM Airlines Logo
2:48 pm - 7:40 amSAT-SCL
13h 52m1 stop
LATAM Airlines Logo
10:35 am - 12:34 amSCL-SAT
16h 59m2 stops
$704LATAM Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Delta Logo
6:30 am - 5:35 amSAT-SCL
20h 05m1 stop
Delta Logo
11:15 pm - 3:21 pmSCL-SAT
19h 06m1 stop
$714Delta
Find Deal
Tue, Jan 20 - Mon, Feb 2
LATAM Airlines Logo
2:10 pm - 7:00 amSAT-SCL
13h 50m1 stop
LATAM Airlines Logo
10:15 pm - 11:33 pmSCL-SAT
28h 18m2 stops
$715LATAM Airlines
Find Deal
Thu, Jan 22 - Sun, Feb 1
LATAM Airlines Logo
4:25 pm - 5:25 pmSAT-SCL
22h 00m2 stops
LATAM Airlines Logo
10:15 pm - 11:33 pmSCL-SAT
28h 18m2 stops
$716LATAM Airlines
Find Deal
Tue, Jan 20 - Sun, Feb 1
LATAM Airlines Logo
6:20 pm - 9:35 pmSAT-SCL
25h 15m3 stops
LATAM Airlines Logo
11:15 pm - 11:30 amSCL-SAT
14h 15m1 stop
$719LATAM Airlines
Find Deal
Sun, Mar 8 - Mon, Mar 16
American Airlines Logo
1:08 pm - 9:05 amSAT-SCL
16h 57m2 stops
American Airlines Logo
10:15 pm - 2:16 pmSCL-SAT
19h 01m2 stops
$720American Airlines
Find Deal
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
1:08 pm - 9:05 amSAT-SCL
16h 57m2 stops
American Airlines Logo
10:15 pm - 2:16 pmSCL-SAT
19h 01m2 stops
$721American Airlines
Find Deal
Tue, Jan 20 - Mon, Feb 2
Delta Logo
6:20 pm - 7:00 amSAT-SCL
34h 40m1 stop
Delta Logo
5:15 am - 12:14 amSCL-SAT
20h 59m2 stops
$723Delta
Find Deal
Sun, Mar 8 - Mon, Mar 16
United Airlines Logo
4:30 pm - 8:50 amSAT-SCL
61h 20m2 stops
United Airlines Logo
10:45 pm - 1:04 pmSCL-SAT
17h 19m1 stop
$775United Airlines
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Sat, Nov 8 - Fri, Nov 14
United Airlines Logo
9:45 am - 8:50 amSAT-SCL
20h 05m1 stop
United Airlines Logo
10:45 pm - 8:48 amSCL-SAT
13h 03m1 stop
$884United Airlines
Find Deal
Wed, Nov 19 - Sat, Nov 29

United Airlines flights from San Antonio to Santiago

Our best United Airlines deals on San Antonio to Santiago flight tickets
United Airlines
Nov 8
SAT4:30 pmSan Antonio
61h 20m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Nov 14
SCL10:45 pmSantiago Arturo Merino Benitez
17h 19m
1 stop
SAT1:04 pmSan Antonio
$775
Find similar
United Airlines
Nov 19
SAT9:45 amSan Antonio
20h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Nov 29
SCL10:45 pmSantiago Arturo Merino Benitez
13h 03m
1 stop
SAT8:48 amSan Antonio
$884
Find similar

American Airlines flights from San Antonio to Santiago

Our best American Airlines deals on San Antonio to Santiago flight tickets
American Airlines
Jan 20
SAT1:08 pmSan Antonio
16h 57m
2 stops
SCL9:05 amSantiago Arturo Merino Benitez
Feb 2
SCL10:15 pmSantiago Arturo Merino Benitez
19h 01m
2 stops
SAT2:16 pmSan Antonio
$720
Find similar
American Airlines
Jan 20
SAT1:08 pmSan Antonio
16h 57m
2 stops
SCL9:05 amSantiago Arturo Merino Benitez
Feb 2
SCL10:15 pmSantiago Arturo Merino Benitez
19h 01m
2 stops
SAT2:16 pmSan Antonio
$721
Find similar
American Airlines
Nov 6
SAT8:34 amSan Antonio
20h 21m
1 stop
SCL7:55 amSantiago Arturo Merino Benitez
Nov 30
SCL11:15 pmSantiago Arturo Merino Benitez
26h 40m
1 stop
SAT10:55 pmSan Antonio
$811
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 12/4

2:48 pm-7:40 am

1 stop13h 52m

Santiago Arturo Merino Benitez

Thu 12/11

10:35 am-12:34 am

2 stops16h 59m

$704

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Mon 2/2

11:15 pm-3:21 pm

1 stop19h 06m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

2:10 pm-7:00 am

1 stop13h 50m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-11:33 pm

2 stops28h 18m

$715

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

4:25 pm-5:25 pm

2 stops22h 00m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-11:33 pm

2 stops28h 18m

$716

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 3/8

6:20 pm-9:35 pm

3 stops25h 15m

Santiago Arturo Merino Benitez

Mon 3/16

11:15 pm-11:30 am

1 stop14h 15m

$719

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

1:08 pm-9:05 am

2 stops16h 57m

Santiago Arturo Merino Benitez

Mon 2/2

10:15 pm-2:16 pm

2 stops19h 01m

$720

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

1:08 pm-9:05 am

2 stops16h 57m

Santiago Arturo Merino Benitez

Mon 2/2

10:15 pm-2:16 pm

2 stops19h 01m

$721

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 3/8

6:20 pm-7:00 am

1 stop34h 40m

Santiago Arturo Merino Benitez

Mon 3/16

5:15 am-12:14 am

2 stops20h 59m

$723

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 11/8

4:30 pm-8:50 am

2 stops61h 20m

Santiago Arturo Merino Benitez

Fri 11/14

10:45 pm-1:04 pm

1 stop17h 19m

$775

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 11/19

9:45 am-8:50 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Sat 11/29

10:45 pm-8:48 am

1 stop13h 03m

$884

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from San Antonio to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from San Antonio to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $778. If you don’t want to visit Santiago in September, then you should wait until January to fly from San Antonio, when ticket prices are also cheap, with an average price of $802.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $742. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,335.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from San Antonio to Santiago when you can find flight prices for as low as $792. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,081 per ticket.

When to book flights from San Antonio to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Santiago (SAT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Santiago

Direct flights

None
There are no direct flights from San Antonio to Santiago. There are no popular flight routes from San Antonio to Santiago.
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  • How far is San Antonio to Santiago Arturo Merino Benitez by plane?

    The distance between San Antonio and Santiago Arturo Merino Benitez is about 4706.7 mi. Typically, this will take 13h 40m by plane in normal conditions.

  • When did momondo last update prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Santiago?

Best airlines flying from San Antonio to Santiago

Compare and see reviews for airlines that fly from San Antonio to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $566Free CancellationRating
7.4
8,988 reviews
Search United Airlines flights
DeltaPriceFrom $753Free CancellationRating
7.9
7,980 reviews
Search Delta flights
American AirlinesPriceFrom $753Free CancellationRating
7.2
11,028 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $753Free CancellationRating
7.5
1,869 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Antonio to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from San Antonio to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Antonio to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Antonio to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Antonio to Santiago.

I’m not ready to book a flight from San Antonio to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from San Antonio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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