Cheap flights from San Antonio to Santiago from $335

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Santiago departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:10 pm - 9:00 am
SAT
-
SCL
12h 50m1 stop
American Airlines Logo
10:30 pm - 4:45 pm
SCL
-
SAT
21h 15m1 stop
$714American Airlines
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
10:32 am - 9:00 am
SAT
-
SCL
19h 28m2 stops
American Airlines Logo
10:30 pm - 4:45 pm
SCL
-
SAT
21h 15m1 stop
$718American Airlines
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
10:32 am - 9:00 am
SAT
-
SCL
19h 28m2 stops
American Airlines Logo
10:30 pm - 12:18 pm
SCL
-
SAT
16h 48m1 stop
$719American Airlines
Tue, Jan 20 - Mon, Feb 2
LATAM Airlines Logo
5:20 am - 7:40 am
SAT
-
SCL
23h 20m1 stop
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$744LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
LATAM Airlines Logo
10:45 am - 7:40 am
SAT
-
SCL
17h 55m1 stop
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$747LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
LATAM Airlines Logo
1:40 pm - 7:40 am
SAT
-
SCL
15h 00m1 stop
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$748LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
Delta Logo
8:00 am - 7:40 am
SAT
-
SCL
20h 40m1 stop
Delta Logo
11:10 pm - 5:22 pm
SCL
-
SAT
21h 12m1 stop
$754Delta
Tue, Jan 20 - Sun, Feb 1
LATAM Airlines Logo
4:29 pm - 2:05 pm
SAT
-
SCL
18h 36m2 stops
LATAM Airlines Logo
4:35 am - 12:38 am
SCL
-
SAT
23h 03m2 stops
$756LATAM Airlines
Tue, Jan 20 - Sat, Jan 31
LATAM Airlines Logo
4:29 pm - 2:05 pm
SAT
-
SCL
18h 36m2 stops
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$757LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
Multiple Airlines Logo
10:35 am - 10:39 am
SAT
-
SCL
21h 04m2 stops
Multiple Airlines Logo
12:35 pm - 9:40 am
SCL
-
SAT
24h 05m2 stops
$759Multiple Airlines
Fri, Jan 23 - Fri, Jan 30

American Airlines flights from San Antonio to Santiago

Our best American Airlines deals on San Antonio to Santiago flight tickets
American Airlines
Jan 20
SAT7:00 amSan Antonio
22h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 2
SCL10:30 pmSantiago Arturo Merino Benitez
23h 56m
1 stop
SAT7:26 pmSan Antonio
American Airlines
Jan 20
SAT9:30 amSan Antonio
20h 30m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 2
SCL10:30 pmSantiago Arturo Merino Benitez
20h 15m
1 stop
SAT3:45 pmSan Antonio
American Airlines
Mar 5
SAT9:15 amSan Antonio
19h 40m
1 stop
SCL7:55 amSantiago Arturo Merino Benitez
Mar 14
SCL10:15 pmSantiago Arturo Merino Benitez
26h 52m
1 stop
SAT11:07 pmSan Antonio

LATAM Airlines flights from San Antonio to Santiago

Our best LATAM Airlines deals on San Antonio to Santiago flight tickets
LATAM Airlines
Jan 20
SAT10:45 amSan Antonio
27h 40m
2 stops
SCL5:25 pmSantiago Arturo Merino Benitez
Feb 1
SCL4:35 amSantiago Arturo Merino Benitez
23h 03m
2 stops
SAT12:38 amSan Antonio
LATAM Airlines
Jan 20
SAT5:20 amSan Antonio
23h 20m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Feb 1
SCL10:15 pmSantiago Arturo Merino Benitez
29h 23m
2 stops
SAT12:38 amSan Antonio
LATAM Airlines
Jan 20
SAT4:29 pmSan Antonio
12h 11m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Feb 1
SCL10:15 pmSantiago Arturo Merino Benitez
29h 23m
2 stops
SAT12:38 amSan Antonio

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

5:10 pm-9:00 am

1 stop12h 50m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-4:45 pm

1 stop21h 15m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:32 am-9:00 am

2 stops19h 28m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-4:45 pm

1 stop21h 15m

$718

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:32 am-9:00 am

2 stops19h 28m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-12:18 pm

1 stop16h 48m

$719

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

5:20 am-7:40 am

1 stop23h 20m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$744

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:45 am-7:40 am

1 stop17h 55m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$747

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

1:40 pm-7:40 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$748

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

8:00 am-7:40 am

1 stop20h 40m

Santiago Arturo Merino Benitez

Sun 2/1

11:10 pm-5:22 pm

1 stop21h 12m

$754

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

4:29 pm-2:05 pm

2 stops18h 36m

Santiago Arturo Merino Benitez

Sat 1/31

4:35 am-12:38 am

2 stops23h 03m

$756

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

4:29 pm-2:05 pm

2 stops18h 36m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$757

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Fri 1/23

10:35 am-10:39 am

2 stops21h 04m

Santiago Arturo Merino Benitez

Fri 1/30

12:35 pm-9:40 am

2 stops24h 05m

$759

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from San Antonio to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from San Antonio to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $778. If you don’t want to visit Santiago in September, then you should wait until November to fly from San Antonio, when ticket prices are also cheap, with an average price of $814.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $742. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,335.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from San Antonio to Santiago when you can find flight prices for as low as $792. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,081 per ticket.

When to book flights from San Antonio to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Santiago (SAT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Santiago

Fastest flight time

15h 00m

Direct flights

None
The fastest flight from San Antonio to Santiago takes 15h 00m
There are no direct flights from San Antonio to Santiago. There are no popular flight routes from San Antonio to Santiago.
  • How far is San Antonio to Santiago Arturo Merino Benitez by plane?

    The distance between San Antonio and Santiago Arturo Merino Benitez is about 4706.7 mi. Typically, this will take 15h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Santiago?

Best airlines flying from San Antonio to Santiago

Compare and see reviews for airlines that fly from San Antonio to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $566Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
DeltaPriceFrom $753Free CancellationRating
7.9
8,009 reviews
Search Delta flights
American AirlinesPriceFrom $753Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $753Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Antonio to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from San Antonio to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Antonio to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Antonio to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Antonio to Santiago.

I’m not ready to book a flight from San Antonio to Santiago right now. Can momondo alert me if prices change?

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1 adult
Sat 1/10
Sat 1/17

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