Cheap flights from San Antonio to Santiago from $429

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Santiago departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:35 am - 2:40 pm
SAT
-
SCL
25h 05m2 stops
Multiple Airlines Logo
12:35 pm - 9:40 am
SCL
-
SAT
24h 05m2 stops
$695Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
10:35 am - 2:40 pm
SAT
-
SCL
25h 05m2 stops
Multiple Airlines Logo
12:35 pm - 9:40 am
SCL
-
SAT
24h 05m2 stops
$709Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Delta Logo
1:40 pm - 7:40 am
SAT
-
SCL
15h 00m1 stop
Delta Logo
11:10 pm - 12:45 pm
SCL
-
SAT
16h 35m1 stop
$714Delta
Thu, Jan 22 - Thu, Jan 29
American Airlines Logo
10:32 am - 8:15 am
SAT
-
SCL
18h 43m1 stop
American Airlines Logo
10:30 pm - 7:26 pm
SCL
-
SAT
23h 56m1 stop
$717American Airlines
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
10:32 am - 9:00 am
SAT
-
SCL
19h 28m2 stops
American Airlines Logo
10:30 pm - 4:45 pm
SCL
-
SAT
21h 15m1 stop
$718American Airlines
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
1:08 pm - 9:00 am
SAT
-
SCL
16h 52m2 stops
American Airlines Logo
11:55 pm - 4:45 pm
SCL
-
SAT
19h 50m2 stops
$719American Airlines
Tue, Jan 20 - Mon, Feb 2
American Airlines Logo
10:32 am - 9:00 am
SAT
-
SCL
19h 28m2 stops
American Airlines Logo
10:30 pm - 9:52 am
SCL
-
SAT
14h 22m1 stop
$721American Airlines
Tue, Jan 20 - Mon, Feb 2
LATAM Airlines Logo
10:45 am - 2:30 pm
SAT
-
SCL
24h 45m3 stops
LATAM Airlines Logo
8:50 am - 9:50 am
SCL
-
SAT
28h 00m2 stops
$722LATAM Airlines
Thu, Jan 22 - Thu, Jan 29
LATAM Airlines Logo
5:20 am - 7:40 am
SAT
-
SCL
23h 20m1 stop
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$744LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
LATAM Airlines Logo
10:45 am - 7:40 am
SAT
-
SCL
17h 55m1 stop
LATAM Airlines Logo
10:15 pm - 12:38 am
SCL
-
SAT
29h 23m2 stops
$747LATAM Airlines
Tue, Jan 20 - Sun, Feb 1

Delta flights from San Antonio to Santiago

Our best Delta deals on San Antonio to Santiago flight tickets
Delta
Jan 22
SAT1:40 pmSan Antonio
15h 00m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Jan 29
SCL11:10 pmSantiago Arturo Merino Benitez
16h 35m
1 stop
SAT12:45 pmSan Antonio
Delta
Mar 6
SAT6:30 amSan Antonio
21h 25m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Mar 29
SCL11:55 pmSantiago Arturo Merino Benitez
26h 37m
2 stops
SAT12:32 amSan Antonio
Delta
Mar 7
SAT12:29 pmSan Antonio
15h 26m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 29
SCL11:25 pmSantiago Arturo Merino Benitez
17h 07m
1 stop
SAT2:32 pmSan Antonio

American Airlines flights from San Antonio to Santiago

Our best American Airlines deals on San Antonio to Santiago flight tickets
American Airlines
Jan 20
SAT10:32 amSan Antonio
18h 43m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 2
SCL10:30 pmSantiago Arturo Merino Benitez
23h 56m
1 stop
SAT7:26 pmSan Antonio
American Airlines
Jan 20
SAT10:32 amSan Antonio
19h 28m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 2
SCL10:30 pmSantiago Arturo Merino Benitez
21h 15m
1 stop
SAT4:45 pmSan Antonio
American Airlines
Jan 20
SAT1:08 pmSan Antonio
16h 52m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 2
SCL11:55 pmSantiago Arturo Merino Benitez
19h 50m
2 stops
SAT4:45 pmSan Antonio

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

10:35 am-2:40 pm

2 stops25h 05m

Santiago Arturo Merino Benitez

Thu 1/29

12:35 pm-9:40 am

2 stops24h 05m

$695

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

10:35 am-2:40 pm

2 stops25h 05m

Santiago Arturo Merino Benitez

Thu 1/29

12:35 pm-9:40 am

2 stops24h 05m

$709

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

1:40 pm-7:40 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Thu 1/29

11:10 pm-12:45 pm

1 stop16h 35m

$714

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:32 am-8:15 am

1 stop18h 43m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-7:26 pm

1 stop23h 56m

$717

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:32 am-9:00 am

2 stops19h 28m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-4:45 pm

1 stop21h 15m

$718

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

1:08 pm-9:00 am

2 stops16h 52m

Santiago Arturo Merino Benitez

Mon 2/2

11:55 pm-4:45 pm

2 stops19h 50m

$719

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:32 am-9:00 am

2 stops19h 28m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-9:52 am

1 stop14h 22m

$721

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

10:45 am-2:30 pm

3 stops24h 45m

Santiago Arturo Merino Benitez

Thu 1/29

8:50 am-9:50 am

2 stops28h 00m

$722

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

5:20 am-7:40 am

1 stop23h 20m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$744

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:45 am-7:40 am

1 stop17h 55m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-12:38 am

2 stops29h 23m

$747

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from San Antonio to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from San Antonio to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $778. If you don’t want to visit Santiago in September, then you should wait until November to fly from San Antonio, when ticket prices are also cheap, with an average price of $814.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $742. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,335.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from San Antonio to Santiago when you can find flight prices for as low as $792. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,081 per ticket.

When to book flights from San Antonio to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Santiago (SAT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Santiago

Fastest flight time

15h 00m

Direct flights

None
The fastest flight from San Antonio to Santiago takes 15h 00m
There are no direct flights from San Antonio to Santiago. There are no popular flight routes from San Antonio to Santiago.
  • How far is San Antonio to Santiago Arturo Merino Benitez by plane?

    The distance between San Antonio and Santiago Arturo Merino Benitez is about 4706.7 mi. Typically, this will take 15h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Antonio Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Antonio to Santiago?

Best airlines flying from San Antonio to Santiago

Compare and see reviews for airlines that fly from San Antonio to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $566Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
DeltaPriceFrom $753Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $753Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $753Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Antonio to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from San Antonio to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Antonio to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Antonio to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Antonio to Santiago.

I’m not ready to book a flight from San Antonio to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from San Antonio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Fri 1/9
Fri 1/16

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