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Cheap flights from San Antonio to Panama from $253

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Panama departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Antonio to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:16 pm - 6:50 am
SAT
-
PTY
8h 34m
1 stop
Multiple Airlines Logo
9:26 pm - 11:00 am
PTY
-
SAT
13h 34m
1 stop
$510Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
10:16 pm - 10:26 am
SAT
-
PTY
12h 10m
1 stop
Multiple Airlines Logo
4:10 pm - 9:05 am
PTY
-
SAT
16h 55m
1 stop
$518Multiple Airlines
Fri, Apr 24 - Tue, Apr 28
Multiple Airlines Logo
10:16 pm - 5:56 am
SAT
-
PTY
7h 40m
1 stop
Multiple Airlines Logo
10:14 pm - 12:02 pm
PTY
-
SAT
13h 48m
1 stop
$577Multiple Airlines
Wed, May 6 - Wed, May 13
United Airlines Logo
7:35 am - 2:14 pm
SAT
-
PTY
6h 39m
1 stop
United Airlines Logo
3:30 pm - 10:38 pm
PTY
-
SAT
7h 08m
1 stop
$582United Airlines
Tue, Sep 1 - Thu, Sep 10
United Airlines Logo
5:30 am - 2:14 pm
SAT
-
PTY
8h 44m
1 stop
United Airlines Logo
10:00 am - 9:13 pm
PTY
-
SAT
11h 13m
1 stop
$591United Airlines
Mon, Jul 6 - Thu, Jul 16
American Airlines Logo
6:14 pm - 12:46 pm
SAT
-
PTY
18h 32m
2 stops
American Airlines Logo
1:49 pm - 11:15 pm
PTY
-
SAT
9h 26m
1 stop
$595American Airlines
Mon, May 11 - Thu, May 14
United Airlines Logo
7:35 pm - 2:14 pm
SAT
-
PTY
18h 39m
1 stop
United Airlines Logo
3:30 pm - 10:42 pm
PTY
-
SAT
7h 12m
1 stop
$598United Airlines
Wed, Jun 24 - Wed, Jul 1
Multiple Airlines Logo
10:16 pm - 2:15 pm
SAT
-
PTY
15h 59m
2 stops
Multiple Airlines Logo
4:10 pm - 11:00 am
PTY
-
SAT
18h 50m
1 stop
$601Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
American Airlines Logo
5:06 am - 2:20 pm
SAT
-
PTY
9h 14m
1 stop
American Airlines Logo
3:40 pm - 2:56 pm
PTY
-
SAT
23h 16m
2 stops
$606American Airlines
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
6:24 pm - 2:20 pm
SAT
-
PTY
19h 56m
2 stops
American Airlines Logo
3:40 pm - 10:32 am
PTY
-
SAT
18h 52m
1 stop
$607American Airlines
Tue, Sep 1 - Thu, Sep 10

American Airlines flights from San Antonio to Panama

Our best American Airlines deals on San Antonio to Panama flight tickets
American Airlines
May 11
SAT6:14 pmSan Antonio
18h 32m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 14
PTY1:49 pmPanama City Tocumen Intl
9h 26m
1 stop
SAT11:15 pmSan Antonio
$595
American Airlines
Sep 1
SAT5:06 amSan Antonio
9h 14m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Sep 10
PTY3:40 pmPanama City Tocumen Intl
23h 16m
2 stops
SAT2:56 pmSan Antonio
$606
American Airlines
Sep 1
SAT6:24 pmSan Antonio
19h 56m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Sep 10
PTY3:40 pmPanama City Tocumen Intl
18h 52m
1 stop
SAT10:32 amSan Antonio
$607

United Airlines flights from San Antonio to Panama

Our best United Airlines deals on San Antonio to Panama flight tickets
United Airlines
Sep 1
SAT7:35 amSan Antonio
6h 39m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Sep 10
PTY3:30 pmPanama City Tocumen Intl
7h 08m
1 stop
SAT10:38 pmSan Antonio
$582
United Airlines
Jul 6
SAT5:30 amSan Antonio
8h 44m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Jul 16
PTY10:00 amPanama City Tocumen Intl
11h 13m
1 stop
SAT9:13 pmSan Antonio
$591
United Airlines
Jun 24
SAT7:35 pmSan Antonio
18h 39m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Jul 1
PTY3:30 pmPanama City Tocumen Intl
7h 12m
1 stop
SAT10:42 pmSan Antonio
$598

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 4/15

10:16 pm-6:50 am

1 stop8h 34m

Panama City Tocumen Intl

Wed 4/22

9:26 pm-11:00 am

1 stop13h 34m

$510

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Fri 4/24

10:16 pm-10:26 am

1 stop12h 10m

Panama City Tocumen Intl

Tue 4/28

4:10 pm-9:05 am

1 stop16h 55m

$518

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 5/6

10:16 pm-5:56 am

1 stop7h 40m

Panama City Tocumen Intl

Wed 5/13

10:14 pm-12:02 pm

1 stop13h 48m

$577
Quickest round-trip

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 9/1

7:35 am-2:14 pm

1 stop6h 39m

Panama City Tocumen Intl

Thu 9/10

3:30 pm-10:38 pm

1 stop7h 08m

$582

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 7/6

5:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Thu 7/16

10:00 am-9:13 pm

1 stop11h 13m

$591

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 5/11

6:14 pm-12:46 pm

2 stops18h 32m

Panama City Tocumen Intl

Thu 5/14

1:49 pm-11:15 pm

1 stop9h 26m

$595

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 6/24

7:35 pm-2:14 pm

1 stop18h 39m

Panama City Tocumen Intl

Wed 7/1

3:30 pm-10:42 pm

1 stop7h 12m

$598

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 4/15

10:16 pm-2:15 pm

2 stops15h 59m

Panama City Tocumen Intl

Wed 4/22

4:10 pm-11:00 am

1 stop18h 50m

$601

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 9/1

5:06 am-2:20 pm

1 stop9h 14m

Panama City Tocumen Intl

Thu 9/10

3:40 pm-2:56 pm

2 stops23h 16m

$606

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 9/1

6:24 pm-2:20 pm

2 stops19h 56m

Panama City Tocumen Intl

Thu 9/10

3:40 pm-10:32 am

1 stop18h 52m

$607

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Antonio to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from San Antonio, with most prices found around $481. If you don’t want to visit Panama in April, then you should wait until June to fly from San Antonio, when ticket prices are also cheap, with an average price of $531.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Antonio when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $607 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Antonio for as low as $510 on momondo.

Can stopping save me money on San Antonio to Panama flights?

You could potentially save up to 43% on your flight if you consider stops on a San Antonio to Panama flight.

Cheap San Antonio to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Panama

Fastest flight time

6h 22m

Direct flights

None
The fastest flight from San Antonio to Panama takes 6h 22m
There are no direct flights from San Antonio to Panama. There are no popular flight routes from San Antonio to Panama.
Search flight deals

  • When did momondo last update prices for flights from San Antonio Airport to Panama?

    Prices for flights from San Antonio Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Antonio Airport to Panama?

  • How old do you have to be to fly from San Antonio Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Antonio to Panama

Compare and see reviews for airlines that fly from San Antonio to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $467Free CancellationRating
7.1
11,492 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,467 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Panama?

It is quick and easy to find San Antonio to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from San Antonio to Panama with flexible booking policies on momondo?

All flight searches from San Antonio to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Antonio to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Antonio to Panama.

I’m not ready to book a flight from San Antonio to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from San Antonio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama trip

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