Latest deals
When to book
FAQs
Price Alerts

Cheap flights from Prague to Chicago from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Prague to Chicago departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Prague to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 4:29 pm
PRG
-
MDW
17h 29m
2 stops
Delta Logo
9:31 am - 8:20 am
MDW
-
PRG
15h 49m
2 stops
$795Delta
Wed, Apr 15 - Wed, May 6
Delta Logo
8:55 am - 5:37 pm
PRG
-
MDW
15h 42m
2 stops
Delta Logo
10:43 am - 8:20 am
MDW
-
PRG
14h 37m
2 stops
$796Delta
Tue, Feb 17 - Tue, Apr 14
Delta Logo
8:55 am - 5:37 pm
PRG
-
MDW
15h 42m
2 stops
Delta Logo
1:29 pm - 10:50 am
MDW
-
PRG
14h 21m
2 stops
$797Delta
Thu, Feb 19 - Wed, Mar 4
Delta Logo
8:55 am - 10:31 pm
PRG
-
MDW
19h 36m
2 stops
Delta Logo
1:10 pm - 8:20 am
MDW
-
PRG
12h 10m
2 stops
$808Delta
Thu, Mar 19 - Sat, Apr 4
Delta Logo
6:00 am - 6:40 pm
PRG
-
MDW
19h 40m
2 stops
Delta Logo
1:22 pm - 8:20 am
MDW
-
PRG
11h 58m
2 stops
$837Delta
Wed, Feb 18 - Sat, May 16
Delta Logo
6:30 am - 5:54 pm
PRG
-
MDW
17h 24m
2 stops
Delta Logo
1:10 pm - 1:45 pm
MDW
-
PRG
17h 35m
2 stops
$843Delta
Fri, Mar 13 - Sun, Mar 29
Delta Logo
8:55 am - 6:40 pm
PRG
-
MDW
16h 45m
2 stops
Delta Logo
1:29 pm - 10:50 am
MDW
-
PRG
14h 21m
2 stops
$902Delta
Thu, Feb 19 - Wed, Mar 4
Delta Logo
6:00 am - 5:58 pm
PRG
-
MDW
18h 58m
2 stops
Delta Logo
5:59 pm - 5:30 pm
MDW
-
PRG
16h 31m
2 stops
$921Delta
Thu, Apr 30 - Sat, Jul 11
Delta Logo
6:00 am - 5:22 pm
PRG
-
MDW
17h 22m
2 stops
Delta Logo
12:47 pm - 8:25 am
MDW
-
PRG
13h 38m
2 stops
$1,021Delta
Thu, Mar 19 - Thu, Mar 26
Delta Logo
6:00 am - 5:56 pm
PRG
-
MDW
18h 56m
2 stops
Delta Logo
1:22 pm - 8:20 am
MDW
-
PRG
11h 58m
2 stops
$1,050Delta
Tue, May 26 - Fri, May 29

Delta flights from Prague to Chicago Midway Airport

Our best Delta deals on Prague to Chicago Midway Airport flight tickets
Delta
Apr 15
PRG6:00 amVáclav Havel Prague
17h 29m
2 stops
MDW4:29 pmChicago Midway
May 6
MDW9:31 amChicago Midway
15h 49m
2 stops
PRG8:20 amVáclav Havel Prague
$795
Delta
Feb 17
PRG8:55 amVáclav Havel Prague
15h 42m
2 stops
MDW5:37 pmChicago Midway
Apr 14
MDW10:43 amChicago Midway
14h 37m
2 stops
PRG8:20 amVáclav Havel Prague
$796
Delta
Feb 19
PRG8:55 amVáclav Havel Prague
15h 42m
2 stops
MDW5:37 pmChicago Midway
Mar 4
MDW1:29 pmChicago Midway
14h 21m
2 stops
PRG10:50 amVáclav Havel Prague
$797

momondo Fare Finder

 
Customize your flight search to find flights from Prague to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Prague to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Wed 4/15

6:00 am-4:29 pm

2 stops17h 29m

Chicago Midway

Wed 5/6

9:31 am-8:20 am

2 stops15h 49m

$795

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Tue 2/17

8:55 am-5:37 pm

2 stops15h 42m

Chicago Midway

Tue 4/14

10:43 am-8:20 am

2 stops14h 37m

$796

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Thu 2/19

8:55 am-5:37 pm

2 stops15h 42m

Chicago Midway

Wed 3/4

1:29 pm-10:50 am

2 stops14h 21m

$797

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Thu 3/19

8:55 am-10:31 pm

2 stops19h 36m

Chicago Midway

Sat 4/4

1:10 pm-8:20 am

2 stops12h 10m

$808

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Wed 2/18

6:00 am-6:40 pm

2 stops19h 40m

Chicago Midway

Sat 5/16

1:22 pm-8:20 am

2 stops11h 58m

$837

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Fri 3/13

6:30 am-5:54 pm

2 stops17h 24m

Chicago Midway

Sun 3/29

1:10 pm-1:45 pm

2 stops17h 35m

$843

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Thu 2/19

8:55 am-6:40 pm

2 stops16h 45m

Chicago Midway

Wed 3/4

1:29 pm-10:50 am

2 stops14h 21m

$902

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Thu 4/30

6:00 am-5:58 pm

2 stops18h 58m

Chicago Midway

Sat 7/11

5:59 pm-5:30 pm

2 stops16h 31m

$921

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Thu 3/19

6:00 am-5:22 pm

2 stops17h 22m

Chicago Midway

Thu 3/26

12:47 pm-8:25 am

2 stops13h 38m

$1,021

PragueChicago

PRG - MDW

PRGMDW

Václav Havel Prague

Tue 5/26

6:00 am-5:56 pm

2 stops18h 56m

Chicago Midway

Fri 5/29

1:22 pm-8:20 am

2 stops11h 58m

$1,050

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

When to book flights from Prague to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Prague to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Prague to Chicago Midway Airport (PRG to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Prague to Chicago Midway Airport

Fastest flight time

16h 46m

Direct flights

None
The fastest flight from Prague to Chicago Midway Airport takes 16h 46m
There are no direct flights from Prague to Chicago Midway Airport. There are no popular flight routes from Prague to Chicago Midway Airport.
Search flight deals

  • How far is Václav Havel Prague to Chicago Midway by plane?

    There are 4541.4 mi between Václav Havel Prague and Chicago Midway. Flights usually cover this in 16h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Václav Havel Prague Airport to Chicago Midway Airport?

    Prices for flights from Václav Havel Prague Airport to Chicago Midway Airport were last updated today.

  • How old do you have to be to fly from Václav Havel Prague Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Václav Havel Prague Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • How do I get Price Alerts for flights from Prague to Chicago Midway Airport?

    Search flight deals from Prague to Chicago Midway Airport. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Prague to Chicago Midway Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Prague to Chicago?

It is quick and easy to find Prague to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Prague to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Prague with this policy.

How can momondo help me find flights from Prague to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Prague to Chicago.

I’m not ready to book a flight from Prague to Chicago right now. Can momondo alert me if prices change?

Price alerts on flights to Chicago from Prague are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Chicago Midway Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 3/5
Thu 3/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chicago