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Cheap flights from Portland, Maine to Santo Domingo from $292

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santo Domingo departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Portland, Maine to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 7:10 pmPWM  Portland-SDQ Santo Domingo Las Americas
12h 10m1 stop New York John F Kennedy Intl
Delta Logo
3:00 pm - 11:55 pmSDQ  Santo Domingo Las Americas-PWM Portland
9h 55m1 stop New York John F Kennedy Intl
$491Delta
Wed, Nov 11 - Sun, Nov 15
Delta Logo
12:50 pm - 1:35 amPWM  Portland-SDQ Santo Domingo Las Americas
11h 45m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl
Delta Logo
3:00 pm - 11:55 pmSDQ  Santo Domingo Las Americas-PWM Portland
9h 55m1 stop New York John F Kennedy Intl
$530Delta
Wed, Nov 11 - Sun, Nov 15
United Airlines Logo
9:45 am - 11:46 pmPWM  Portland-SDQ Santo Domingo Las Americas
13h 01m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
4:18 pm - 1:52 pmSDQ  Santo Domingo Las Americas-PWM Portland
22h 34m2 stops Newark Chicago O'Hare Intl
$567United Airlines
Tue, Feb 2 - Fri, Feb 5
United Airlines Logo
6:00 am - 3:06 pmPWM  Portland-SDQ Santo Domingo Las Americas
8h 06m1 stop Newark
United Airlines Logo
2:53 pm - 1:38 pmSDQ  Santo Domingo Las Americas-PWM Portland
23h 45m1 stop Newark
$569United Airlines
Tue, Feb 2 - Fri, Feb 5
United Airlines Logo
9:45 am - 11:46 pmPWM  Portland-SDQ Santo Domingo Las Americas
13h 01m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
4:18 pm - 1:52 pmSDQ  Santo Domingo Las Americas-PWM Portland
22h 34m2 stops Newark Chicago O'Hare Intl
$587United Airlines
Tue, Feb 2 - Fri, Feb 5
United Airlines Logo
6:00 am - 3:06 pmPWM  Portland-SDQ Santo Domingo Las Americas
8h 06m1 stop Newark
United Airlines Logo
2:53 pm - 1:38 pmSDQ  Santo Domingo Las Americas-PWM Portland
23h 45m1 stop Newark
$589United Airlines
Tue, Feb 2 - Fri, Feb 5
Delta Logo
12:50 pm - 1:35 amPWM  Portland-SDQ Santo Domingo Las Americas
11h 45m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl
Delta Logo
8:35 pm - 12:08 pmSDQ  Santo Domingo Las Americas-PWM Portland
16h 33m2 stops New York John F Kennedy Intl Detroit Metropolitan Wayne County
$639Delta
Wed, Nov 11 - Sun, Nov 15
United Airlines Logo
3:40 pm - 10:46 pmPWM  Portland-SDQ Santo Domingo Las Americas
7h 06m1 stop Newark
United Airlines Logo
6:00 am - 10:07 amSDQ  Santo Domingo Las Americas-PWM Portland
29h 07m2 stops Newark Washington, D.C. Dulles Intl
$647United Airlines
Wed, Oct 28 - Sun, Nov 1
United Airlines Logo
5:50 am - 2:06 pmPWM  Portland-SDQ Santo Domingo Las Americas
8h 16m1 stop Newark
United Airlines Logo
6:00 am - 11:21 pmSDQ  Santo Domingo Las Americas-PWM Portland
18h 21m1 stop Newark
$651United Airlines
Wed, Oct 28 - Sun, Nov 1

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United Airlines flights from Portland, Maine to Santo Domingo

Our best United Airlines deals on Portland, Maine to Santo Domingo flight tickets
United Airlines
Feb 2
PWM9:45 amPortland
13h 01m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 5
SDQ4:18 pmSanto Domingo Las Americas
22h 34m
2 stops
PWM1:52 pmPortland
$567
United Airlines
Feb 2
PWM6:00 amPortland
8h 06m
1 stop
SDQ3:06 pmSanto Domingo Las Americas
Feb 5
SDQ2:53 pmSanto Domingo Las Americas
23h 45m
1 stop
PWM1:38 pmPortland
$569
United Airlines
Feb 2
PWM9:45 amPortland
13h 01m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 5
SDQ4:18 pmSanto Domingo Las Americas
22h 34m
2 stops
PWM1:52 pmPortland
$587

Delta flights from Portland, Maine to Santo Domingo

Our best Delta deals on Portland, Maine to Santo Domingo flight tickets
Delta
Nov 11
PWM6:00 amPortland
12h 10m
1 stop
SDQ7:10 pmSanto Domingo Las Americas
Nov 15
SDQ3:00 pmSanto Domingo Las Americas
9h 55m
1 stop
PWM11:55 pmPortland
$491
Delta
Nov 11
PWM12:50 pmPortland
11h 45m
2 stops
SDQ1:35 amSanto Domingo Las Americas
Nov 15
SDQ3:00 pmSanto Domingo Las Americas
9h 55m
1 stop
PWM11:55 pmPortland
$530
Delta
Nov 11
PWM12:50 pmPortland
11h 45m
2 stops
SDQ1:35 amSanto Domingo Las Americas
Nov 15
SDQ8:35 pmSanto Domingo Las Americas
16h 33m
2 stops
PWM12:08 pmPortland
$639

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Portland, Maine to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Wed 11/11

6:00 am-7:10 pm

1 stop12h 10m

Santo Domingo Las Americas

Sun 11/15

3:00 pm-11:55 pm

1 stop9h 55m

$491
Quickest round-trip

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Wed 11/11

12:50 pm-1:35 am

2 stops11h 45m

Santo Domingo Las Americas

Sun 11/15

3:00 pm-11:55 pm

1 stop9h 55m

$530

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Tue 2/2

9:45 am-11:46 pm

2 stops13h 01m

Santo Domingo Las Americas

Fri 2/5

4:18 pm-1:52 pm

2 stops22h 34m

$567

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Tue 2/2

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Fri 2/5

2:53 pm-1:38 pm

1 stop23h 45m

$569

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Tue 2/2

9:45 am-11:46 pm

2 stops13h 01m

Santo Domingo Las Americas

Fri 2/5

4:18 pm-1:52 pm

2 stops22h 34m

$587

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Tue 2/2

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Fri 2/5

2:53 pm-1:38 pm

1 stop23h 45m

$589

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Wed 11/11

12:50 pm-1:35 am

2 stops11h 45m

Santo Domingo Las Americas

Sun 11/15

8:35 pm-12:08 pm

2 stops16h 33m

$639

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Wed 10/28

3:40 pm-10:46 pm

1 stop7h 06m

Santo Domingo Las Americas

Sun 11/1

6:00 am-10:07 am

2 stops29h 07m

$647

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Wed 10/28

5:50 am-2:06 pm

1 stop8h 16m

Santo Domingo Las Americas

Sun 11/1

6:00 am-11:21 pm

1 stop18h 21m

$651
Cheapest one-way

PortlandSanto Domingo

PWM Portland - SDQ Santo Domingo Las Americas

PWMSDQ

Portland

Tue 9/8

6:00 am-2:10 pm

2 stops32h 10m

$292

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Portland, Maine to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Portland to Santo Domingo Las Americas?

United Airlines and American Airlines are the most popular carriers operating from Portland to Santo Domingo Las Americas

What airlines fly to Santo Domingo?

JetBlue, Arajet and American Airlines are the top three most popular airlines that fly to Santo Domingo from Portland, Maine according to our data. JetBlue is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Santo Domingo. Keep in mind that there are 8 different airlines that fly to Santo Domingo on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santo Domingo (PWM to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santo Domingo

Fastest flight time

12h 10m

Direct flights

None
The fastest flight from Portland, Maine to Santo Domingo takes 12h 10m
There are no direct flights from Portland, Maine to Santo Domingo. There are no popular flight routes from Portland, Maine to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Santo Domingo

  • How far is Portland to Santo Domingo Las Americas by plane?

    A flight from Portland to Santo Domingo Las Americas will travel around 1738.5 mi. By plane, this route typically takes 12h 10m.

  • When did momondo last update prices for flights from Portland Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Portland Airport to Santo Domingo Las Americas Airport refresh daily.

  • How old do you have to be to fly from Portland Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santo Domingo for you.

Can I find flights from Portland to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Portland on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Portland to Santo Domingo?

Once you have performed a search for Portland to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Portland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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