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Cheap flights from Portland, Maine to Santo Domingo from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santo Domingo departing on 12/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland, Maine to Santo Domingo

Cheap round-trip flights

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American Airlines Logo
5:17 pm - 12:01 pmPWM-SDQ
17h 44m2 stops
American Airlines Logo
6:00 am - 11:37 pmSDQ-PWM
18h 37m2 stops
$328American Airlines
Find Deal
Tue, Dec 9 - Fri, Dec 12
American Airlines Logo
5:20 pm - 12:30 pmPWM-SDQ
19h 10m2 stops
American Airlines Logo
5:45 am - 10:30 pmSDQ-PWM
16h 45m2 stops
$406American Airlines
Find Deal
Mon, Mar 30 - Fri, Apr 3
JetBlue Logo
2:20 pm - 12:04 amPWM-SDQ
9h 44m1 stop
JetBlue Logo
4:05 am - 1:23 pmSDQ-PWM
9h 18m1 stop
$455JetBlue
Find Deal
Mon, Mar 30 - Fri, Apr 3
Delta Logo
12:53 pm - 1:48 amPWM-SDQ
11h 55m2 stops
Delta Logo
2:54 pm - 11:59 pmSDQ-PWM
10h 05m1 stop
$542Delta
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Tue, Dec 9 - Fri, Dec 12
American Airlines Logo
6:41 pm - 2:16 pmPWM-SDQ
18h 35m2 stops
American Airlines Logo
4:47 pm - 12:05 pmSDQ-PWM
20h 18m2 stops
$645American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13
American Airlines Logo
6:41 pm - 10:00 pmPWM-SDQ
26h 19m1 stop
American Airlines Logo
7:00 am - 10:54 pmSDQ-PWM
16h 54m1 stop
$649American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13
American Airlines Logo
6:41 pm - 2:16 pmPWM-SDQ
18h 35m2 stops
American Airlines Logo
3:00 pm - 12:06 pmSDQ-PWM
22h 06m2 stops
$665American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13
American Airlines Logo
6:41 pm - 10:00 pmPWM-SDQ
26h 19m1 stop
American Airlines Logo
3:00 pm - 12:06 pmSDQ-PWM
22h 06m2 stops
$674American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13
American Airlines Logo
6:41 pm - 3:49 pmPWM-SDQ
20h 08m2 stops
American Airlines Logo
7:00 am - 10:54 pmSDQ-PWM
16h 54m1 stop
$680American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13
American Airlines Logo
6:41 pm - 10:00 pmPWM-SDQ
26h 19m1 stop
American Airlines Logo
7:00 am - 10:54 pmSDQ-PWM
16h 54m1 stop
$684American Airlines
Find Deal
Fri, Jan 2 - Tue, Jan 13

American Airlines flights from Portland, Maine to Santo Domingo

Our best American Airlines deals on Portland, Maine to Santo Domingo flight tickets
American Airlines
Dec 9
PWM5:17 pmPortland
17h 44m
2 stops
SDQ12:01 pmSanto Domingo Las Americas
Dec 12
SDQ6:00 amSanto Domingo Las Americas
18h 37m
2 stops
PWM11:37 pmPortland
$328
Find similar
American Airlines
Mar 30
PWM5:20 pmPortland
19h 10m
2 stops
SDQ12:30 pmSanto Domingo Las Americas
Apr 3
SDQ5:45 amSanto Domingo Las Americas
16h 45m
2 stops
PWM10:30 pmPortland
$406
Find similar
American Airlines
Jan 2
PWM6:41 pmPortland
18h 35m
2 stops
SDQ2:16 pmSanto Domingo Las Americas
Jan 13
SDQ4:47 pmSanto Domingo Las Americas
20h 18m
2 stops
PWM12:05 pmPortland
$645
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Portland, Maine to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Tue 12/9

5:17 pm-12:01 pm

2 stops17h 44m

Santo Domingo Las Americas

Fri 12/12

6:00 am-11:37 pm

2 stops18h 37m

$328

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 3/30

5:20 pm-12:30 pm

2 stops19h 10m

Santo Domingo Las Americas

Fri 4/3

5:45 am-10:30 pm

2 stops16h 45m

$406

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 3/30

2:20 pm-12:04 am

1 stop9h 44m

Santo Domingo Las Americas

Fri 4/3

4:05 am-1:23 pm

1 stop9h 18m

$455

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Tue 12/9

12:53 pm-1:48 am

2 stops11h 55m

Santo Domingo Las Americas

Fri 12/12

2:54 pm-11:59 pm

1 stop10h 05m

$542

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-2:16 pm

2 stops18h 35m

Santo Domingo Las Americas

Tue 1/13

4:47 pm-12:05 pm

2 stops20h 18m

$645

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-10:00 pm

1 stop26h 19m

Santo Domingo Las Americas

Tue 1/13

7:00 am-10:54 pm

1 stop16h 54m

$649

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-2:16 pm

2 stops18h 35m

Santo Domingo Las Americas

Tue 1/13

3:00 pm-12:06 pm

2 stops22h 06m

$665

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-10:00 pm

1 stop26h 19m

Santo Domingo Las Americas

Tue 1/13

3:00 pm-12:06 pm

2 stops22h 06m

$674

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-3:49 pm

2 stops20h 08m

Santo Domingo Las Americas

Tue 1/13

7:00 am-10:54 pm

1 stop16h 54m

$680

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 1/2

6:41 pm-10:00 pm

1 stop26h 19m

Santo Domingo Las Americas

Tue 1/13

7:00 am-10:54 pm

1 stop16h 54m

$684

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Portland, Maine to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is at noon when flights can be purchased for as low as $458. Try not to purchase tickets in the morning because they tend to be around $492. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Portland, Maine to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santo Domingo (PWM to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santo Domingo

Direct flights

None
There are no direct flights from Portland, Maine to Santo Domingo. There are no popular flight routes from Portland, Maine to Santo Domingo.
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  • How far is Portland to Santo Domingo Las Americas by plane?

    A flight from Portland to Santo Domingo Las Americas will travel around 1738.5 mi. By plane, this route typically takes 9h 24m.

  • When did momondo last update prices for flights from Portland Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Portland Airport to Santo Domingo Las Americas Airport refresh daily.

  • How old do you have to be to fly from Portland Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santo Domingo for you.

Can I find flights from Portland to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Portland on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Portland to Santo Domingo?

Once you have performed a search for Portland to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Portland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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