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Cheap flights from Portland, Maine to Santo Domingo from $375

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santo Domingo departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Portland, Maine to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:20 am - 6:21 pm
PWM
-
SDQ
11h 01m
1 stop
JetBlue Logo
3:39 pm - 11:03 pm
SDQ
-
PWM
7h 24m
1 stop
$375JetBlue
Thu, May 7 - Mon, May 11
Delta Logo
2:59 pm - 12:42 am
PWM
-
SDQ
9h 43m
1 stop
Delta Logo
6:06 am - 2:19 pm
SDQ
-
PWM
8h 13m
1 stop
$386Delta
Tue, Jun 9 - Sun, Jun 21
JetBlue Logo
6:00 am - 5:55 pm
PWM
-
SDQ
11h 55m
1 stop
JetBlue Logo
3:35 pm - 11:52 pm
SDQ
-
PWM
8h 17m
1 stop
$412JetBlue
Sat, Sep 26 - Wed, Sep 30
JetBlue Logo
6:00 am - 5:55 pm
PWM
-
SDQ
11h 55m
1 stop
JetBlue Logo
12:10 pm - 11:52 pm
SDQ
-
PWM
11h 42m
1 stop
$425JetBlue
Sat, Sep 26 - Wed, Sep 30
JetBlue Logo
6:00 am - 5:55 pm
PWM
-
SDQ
11h 55m
1 stop
JetBlue Logo
3:35 pm - 11:52 pm
SDQ
-
PWM
8h 17m
1 stop
$432JetBlue
Sat, Sep 26 - Wed, Sep 30
American Airlines Logo
6:00 am - 4:55 pm
PWM
-
SDQ
10h 55m
2 stops
American Airlines Logo
4:00 pm - 10:07 am
SDQ
-
PWM
18h 07m
2 stops
$456American Airlines
Thu, May 7 - Mon, May 11
JetBlue Logo
7:20 am - 6:21 pm
PWM
-
SDQ
11h 01m
1 stop
JetBlue Logo
5:01 am - 11:03 pm
SDQ
-
PWM
18h 02m
2 stops
$468JetBlue
Thu, May 7 - Mon, May 11
United Airlines Logo
6:20 pm - 2:10 pm
PWM
-
SDQ
19h 50m
2 stops
United Airlines Logo
6:00 am - 1:42 pm
SDQ
-
PWM
7h 42m
1 stop
$553United Airlines
Sat, Sep 26 - Wed, Sep 30
American Airlines Logo
6:54 pm - 12:45 pm
PWM
-
SDQ
17h 51m
1 stop
American Airlines Logo
7:00 am - 9:46 pm
SDQ
-
PWM
14h 46m
2 stops
$558American Airlines
Tue, Jun 9 - Sun, Jun 21
United Airlines Logo
6:20 pm - 2:10 pm
PWM
-
SDQ
19h 50m
2 stops
United Airlines Logo
6:00 am - 1:42 pm
SDQ
-
PWM
7h 42m
1 stop
$573United Airlines
Sat, Sep 26 - Wed, Sep 30

JetBlue flights from Portland, Maine to Santo Domingo

Our best JetBlue deals on Portland, Maine to Santo Domingo flight tickets
JetBlue
May 7
PWM7:20 amPortland
11h 01m
1 stop
SDQ6:21 pmSanto Domingo Las Americas
May 11
SDQ3:39 pmSanto Domingo Las Americas
7h 24m
1 stop
PWM11:03 pmPortland
$375
JetBlue
Sep 26
PWM6:00 amPortland
11h 55m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
Sep 30
SDQ3:35 pmSanto Domingo Las Americas
8h 17m
1 stop
PWM11:52 pmPortland
$412
JetBlue
Sep 26
PWM6:00 amPortland
11h 55m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
Sep 30
SDQ12:10 pmSanto Domingo Las Americas
11h 42m
1 stop
PWM11:52 pmPortland
$425

Delta flights from Portland, Maine to Santo Domingo

Our best Delta deals on Portland, Maine to Santo Domingo flight tickets
Delta
Jun 9
PWM2:59 pmPortland
9h 43m
1 stop
SDQ12:42 amSanto Domingo Las Americas
Jun 21
SDQ6:06 amSanto Domingo Las Americas
8h 13m
1 stop
PWM2:19 pmPortland
$386
Delta
Apr 20
PWM2:51 pmPortland
9h 26m
1 stop
SDQ12:17 amSanto Domingo Las Americas
Apr 25
SDQ6:05 amSanto Domingo Las Americas
8h 06m
1 stop
PWM2:11 pmPortland
$640
Delta
Apr 20
PWM12:46 pmPortland
11h 31m
2 stops
SDQ12:17 amSanto Domingo Las Americas
Apr 25
SDQ6:05 amSanto Domingo Las Americas
8h 06m
1 stop
PWM2:11 pmPortland
$707

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Portland, Maine to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Thu 5/7

7:20 am-6:21 pm

1 stop11h 01m

Santo Domingo Las Americas

Mon 5/11

3:39 pm-11:03 pm

1 stop7h 24m

$375
Quickest round-trip

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Tue 6/9

2:59 pm-12:42 am

1 stop9h 43m

Santo Domingo Las Americas

Sun 6/21

6:06 am-2:19 pm

1 stop8h 13m

$386

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 9/26

6:00 am-5:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Wed 9/30

3:35 pm-11:52 pm

1 stop8h 17m

$412

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 9/26

6:00 am-5:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Wed 9/30

12:10 pm-11:52 pm

1 stop11h 42m

$425

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 9/26

6:00 am-5:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Wed 9/30

3:35 pm-11:52 pm

1 stop8h 17m

$432

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Thu 5/7

6:00 am-4:55 pm

2 stops10h 55m

Santo Domingo Las Americas

Mon 5/11

4:00 pm-10:07 am

2 stops18h 07m

$456

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Thu 5/7

7:20 am-6:21 pm

1 stop11h 01m

Santo Domingo Las Americas

Mon 5/11

5:01 am-11:03 pm

2 stops18h 02m

$468

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 9/26

6:20 pm-2:10 pm

2 stops19h 50m

Santo Domingo Las Americas

Wed 9/30

6:00 am-1:42 pm

1 stop7h 42m

$553

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Tue 6/9

6:54 pm-12:45 pm

1 stop17h 51m

Santo Domingo Las Americas

Sun 6/21

7:00 am-9:46 pm

2 stops14h 46m

$558

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 9/26

6:20 pm-2:10 pm

2 stops19h 50m

Santo Domingo Las Americas

Wed 9/30

6:00 am-1:42 pm

1 stop7h 42m

$573

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Portland, Maine to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Santo Domingo?

JetBlue, Arajet and Spirit Airlines are the top three most popular airlines that fly to Santo Domingo from Portland, Maine according to our data. JetBlue is the first choice among our users, with 79% of people opting to fly with this airline when traveling to Santo Domingo. Keep in mind that there are 10 different airlines that fly to Santo Domingo on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santo Domingo (PWM to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santo Domingo

Fastest flight time

9h 26m

Direct flights

None
The fastest flight from Portland, Maine to Santo Domingo takes 9h 26m
There are no direct flights from Portland, Maine to Santo Domingo. There are no popular flight routes from Portland, Maine to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Santo Domingo

  • How far is Portland to Santo Domingo Las Americas by plane?

    A flight from Portland to Santo Domingo Las Americas will travel around 1738.5 mi. By plane, this route typically takes 9h 26m.

  • When did momondo last update prices for flights from Portland Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Portland Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Portland Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Portland, Maine to Santo Domingo?

Best airlines flying from Portland, Maine to Santo Domingo

Compare and see reviews for airlines that fly from Portland, Maine to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $416Free CancellationRating
7.4
9,554 reviews
Search United Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santo Domingo for you.

Can I find flights from Portland to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Portland on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Portland to Santo Domingo?

Once you have performed a search for Portland to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Portland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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