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Cheap flights from Ohio to Guayaquil from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Guayaquil departing on 9/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Ohio to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:00 am - 3:14 pm
DTW
-
GYE
9h 14m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$398JetBlue
Mon, Sep 14 - Tue, Sep 22
American Airlines Logo
7:13 pm - 1:33 pm
DTW
-
GYE
19h 20m
2 stops
American Airlines Logo
2:30 pm - 12:28 pm
GYE
-
DTW
20h 58m
2 stops
$407American Airlines
Sat, Oct 17 - Sat, Oct 24
JetBlue Logo
6:00 am - 3:20 pm
DTW
-
GYE
10h 20m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$432JetBlue
Wed, Aug 26 - Wed, Sep 9
GOL Logo
7:59 pm - 10:11 pm
DTW
-
GYE
27h 12m
2 stops
GOL Logo
2:30 pm - 10:53 am
GYE
-
DTW
19h 23m
2 stops
$440GOL
Sun, Sep 27 - Mon, Oct 5
JetBlue Logo
3:50 pm - 3:14 pm
DTW
-
GYE
24h 24m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$471JetBlue
Sun, Sep 27 - Mon, Oct 5
Multiple Airlines Logo
7:00 am - 3:14 pm
DTW
-
GYE
9h 14m
1 stop
Multiple Airlines Logo
1:21 pm - 9:56 pm
GYE
-
DTW
31h 35m
2 stops
$530Multiple Airlines
Mon, Sep 14 - Tue, Sep 22
Copa Airlines Logo
6:35 am - 5:31 pm
CVG
-
GYE
11h 56m
2 stops
Copa Airlines Logo
8:28 am - 3:57 pm
GYE
-
CVG
30h 29m
2 stops
$821Copa Airlines
Mon, Aug 3 - Mon, Aug 10
Copa Airlines Logo
9:00 am - 12:02 am
CMH
-
GYE
16h 02m
2 stops
Copa Airlines Logo
12:22 pm - 9:57 am
GYE
-
CMH
20h 35m
2 stops
$839Copa Airlines
Fri, Jul 31 - Mon, Aug 3
United Airlines Logo
6:38 pm - 11:37 pm
CAK
-
GYE
29h 59m
2 stops
United Airlines Logo
2:37 pm - 11:59 pm
GYE
-
CAK
32h 22m
2 stops
$1,120United Airlines
Sun, Sep 20 - Thu, Sep 24
United Airlines Logo
7:45 pm - 5:35 pm
DAY
-
GYE
21h 50m
2 stops
United Airlines Logo
12:24 pm - 10:23 pm
GYE
-
DAY
33h 59m
2 stops
$1,163United Airlines
Mon, Nov 2 - Thu, Nov 5

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American Airlines flights from Ohio to Guayaquil

Our best American Airlines deals on Ohio to Guayaquil flight tickets
American Airlines
Oct 17
DTW7:13 pmDetroit Metropolitan Wayne County
19h 20m
2 stops
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE2:30 pmGuayaquil Jose Joaquin de Olmedo
20h 58m
2 stops
DTW12:28 pmDetroit Metropolitan Wayne County
$407
American Airlines
Oct 17
DTW7:13 pmDetroit Metropolitan Wayne County
19h 20m
2 stops
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE8:25 amGuayaquil Jose Joaquin de Olmedo
13h 16m
1 stop
DTW10:41 pmDetroit Metropolitan Wayne County
$553
American Airlines
Sep 27
DTW6:00 amDetroit Metropolitan Wayne County
17h 11m
1 stop
GYE10:11 pmGuayaquil Jose Joaquin de Olmedo
Oct 5
GYE2:30 pmGuayaquil Jose Joaquin de Olmedo
21h 00m
2 stops
DTW12:30 pmDetroit Metropolitan Wayne County
$557

JetBlue flights from Ohio to Guayaquil

Our best JetBlue deals on Ohio to Guayaquil flight tickets
JetBlue
Sep 14
DTW7:00 amDetroit Metropolitan Wayne County
9h 14m
1 stop
GYE3:14 pmGuayaquil Jose Joaquin de Olmedo
Sep 22
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$398
JetBlue
Aug 26
DTW6:00 amDetroit Metropolitan Wayne County
10h 20m
1 stop
GYE3:20 pmGuayaquil Jose Joaquin de Olmedo
Sep 9
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$432
JetBlue
Sep 27
DTW3:50 pmDetroit Metropolitan Wayne County
24h 24m
1 stop
GYE3:14 pmGuayaquil Jose Joaquin de Olmedo
Oct 5
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$471

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 9/14

7:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 9/22

12:30 pm-11:30 pm

1 stop10h 00m

$398

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

7:13 pm-1:33 pm

2 stops19h 20m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

2:30 pm-12:28 pm

2 stops20h 58m

$407

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 8/26

6:00 am-3:20 pm

1 stop10h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 9/9

12:30 pm-11:30 pm

1 stop10h 00m

$432

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 9/27

7:59 pm-10:11 pm

2 stops27h 12m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

2:30 pm-10:53 am

2 stops19h 23m

$440

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 9/27

3:50 pm-3:14 pm

1 stop24h 24m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

12:30 pm-11:30 pm

1 stop10h 00m

$471

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 9/14

7:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 9/22

1:21 pm-9:56 pm

2 stops31h 35m

$530

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Mon 8/3

6:35 am-5:31 pm

2 stops11h 56m

Guayaquil Jose Joaquin de Olmedo

Mon 8/10

8:28 am-3:57 pm

2 stops30h 29m

$821

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 7/31

9:00 am-12:02 am

2 stops16h 02m

Guayaquil Jose Joaquin de Olmedo

Mon 8/3

12:22 pm-9:57 am

2 stops20h 35m

$839

AkronGuayaquil

CAK - GYE

CAKGYE

Akron/Canton

Sun 9/20

6:38 pm-11:37 pm

2 stops29h 59m

Guayaquil Jose Joaquin de Olmedo

Thu 9/24

2:37 pm-11:59 pm

2 stops32h 22m

$1,120

DaytonGuayaquil

DAY - GYE

DAYGYE

Dayton

Mon 11/2

7:45 pm-5:35 pm

2 stops21h 50m

Guayaquil Jose Joaquin de Olmedo

Thu 11/5

12:24 pm-10:23 pm

2 stops33h 59m

$1,163

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from Ohio to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of January is another great option to travel to Guayaquil, with average flight prices from Ohio averaging around $466.

Can stopping save me money on Ohio to Guayaquil flights?

You could potentially save up to 48% on your flight if you consider stops on a Ohio to Guayaquil flight.

Cheap Ohio to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Guayaquil

Fastest flight time

8h 20m

Direct flights

None
The fastest flight from Ohio to Guayaquil takes 8h 20m
There are no direct flights from Ohio to Guayaquil. There are no popular flight routes from Ohio to Guayaquil.
Search flight deals

Frequently asked questions about flying from Ohio to Guayaquil

  • When did momondo last update prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Guayaquil

Compare and see reviews for airlines that fly from Ohio to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $663Free CancellationRating
7.1
11,723 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Guayaquil?

It is quick and easy to find Ohio to Guayaquil flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guayaquil that suits you.

Can I find flights from Ohio to Guayaquil with flexible booking policies on momondo?

All flight searches from Ohio to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Ohio to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Guayaquil.

I’m not ready to book a flight from Ohio to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Ohio and alert you when they change.

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