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Cheap flights from Ohio to Guayaquil from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Guayaquil departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
4:39 pm - 5:35 amDTW-GYE
12h 56m1 stop
Multiple Airlines Logo
12:49 am - 10:08 amGYE-DTW
9h 19m1 stop
$339Multiple Airlines
Find Deal
Thu, Dec 4 - Tue, Dec 9
Multiple Airlines Logo
4:39 pm - 5:35 amDTW-GYE
12h 56m1 stop
Multiple Airlines Logo
12:49 am - 12:09 amGYE-DTW
23h 20m2 stops
$348Multiple Airlines
Find Deal
Thu, Dec 4 - Fri, Dec 12
Spirit Airlines Logo
7:49 am - 11:43 pmDTW-GYE
15h 54m1 stop
Spirit Airlines Logo
12:49 am - 7:34 pmGYE-DTW
18h 45m1 stop
$367Spirit Airlines
Find Deal
Thu, Dec 11 - Wed, Dec 17
Spirit Airlines Logo
6:00 am - 11:43 pmDTW-GYE
17h 43m1 stop
Spirit Airlines Logo
12:49 am - 10:08 amGYE-DTW
9h 19m1 stop
$369Spirit Airlines
Find Deal
Tue, Dec 9 - Mon, Dec 15
American Airlines Logo
10:54 am - 10:42 pmCMH-GYE
11h 48m1 stop
American Airlines Logo
3:31 pm - 10:24 amGYE-CMH
18h 53m1 stop
$652American Airlines
Find Deal
Mon, Feb 16 - Sun, Mar 1
American Airlines Logo
6:36 am - 10:42 pmCMH-GYE
16h 06m2 stops
American Airlines Logo
3:31 pm - 10:24 amGYE-CMH
18h 53m1 stop
$657American Airlines
Find Deal
Mon, Feb 16 - Sun, Mar 1
United Airlines Logo
6:30 am - 5:36 pmCVG-GYE
35h 06m2 stops
United Airlines Logo
2:35 pm - 11:44 pmGYE-CVG
33h 09m2 stops
$670United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
Delta Logo
4:16 pm - 7:20 amDAY-GYE
39h 04m2 stops
Delta Logo
4:30 pm - 5:47 pmGYE-DAY
25h 17m2 stops
$700Delta
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Sat, Dec 6 - Tue, Dec 9
Delta Logo
12:05 pm - 7:20 amCMH-GYE
20h 15m1 stop
Delta Logo
4:00 pm - 11:41 amGYE-CMH
18h 41m1 stop
$703Delta
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Sun, May 3 - Wed, May 6
United Airlines Logo
6:45 am - 5:35 pmCMH-GYE
11h 50m2 stops
United Airlines Logo
2:35 pm - 9:54 amGYE-CMH
18h 19m2 stops
$716United Airlines
Find Deal
Sun, May 3 - Wed, May 6

Spirit Airlines flights from Ohio to Guayaquil

Our best Spirit Airlines deals on Ohio to Guayaquil flight tickets
Spirit Airlines
Dec 11
DTW7:49 amDetroit Metropolitan Wayne County
15h 54m
1 stop
GYE11:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 17
GYE12:49 amGuayaquil Jose Joaquin de Olmedo
18h 45m
1 stop
DTW7:34 pmDetroit Metropolitan Wayne County
$367
Find similar
Spirit Airlines
Dec 9
DTW6:00 amDetroit Metropolitan Wayne County
17h 43m
1 stop
GYE11:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 15
GYE12:49 amGuayaquil Jose Joaquin de Olmedo
9h 19m
1 stop
DTW10:08 amDetroit Metropolitan Wayne County
$369
Find similar
Spirit Airlines
Dec 11
DTW6:00 amDetroit Metropolitan Wayne County
17h 43m
2 stops
GYE11:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 17
GYE12:49 amGuayaquil Jose Joaquin de Olmedo
8h 44m
1 stop
DTW9:33 amDetroit Metropolitan Wayne County
$370
Find similar

LATAM Airlines flights from Ohio to Guayaquil

Our best LATAM Airlines deals on Ohio to Guayaquil flight tickets
LATAM Airlines
Apr 7
CLE6:00 pmCleveland Hopkins Intl
14h 20m
1 stop
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Apr 8
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
18h 28m
1 stop
CLE11:28 amCleveland Hopkins Intl
$794
Find similar
LATAM Airlines
Apr 7
CLE6:00 pmCleveland Hopkins Intl
14h 20m
1 stop
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Apr 8
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
18h 28m
1 stop
CLE11:28 amCleveland Hopkins Intl
$814
Find similar
LATAM Airlines
Apr 7
CVG6:30 pmCincinnati Cinci./N. Kentucky
13h 50m
1 stop
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Apr 8
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
18h 13m
1 stop
CVG11:13 amCincinnati Cinci./N. Kentucky
$827
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 12/4

4:39 pm-5:35 am

1 stop12h 56m

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

12:49 am-10:08 am

1 stop9h 19m

$339

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 12/4

4:39 pm-5:35 am

1 stop12h 56m

Guayaquil Jose Joaquin de Olmedo

Fri 12/12

12:49 am-12:09 am

2 stops23h 20m

$348

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 12/11

7:49 am-11:43 pm

1 stop15h 54m

Guayaquil Jose Joaquin de Olmedo

Wed 12/17

12:49 am-7:34 pm

1 stop18h 45m

$367

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 12/9

6:00 am-11:43 pm

1 stop17h 43m

Guayaquil Jose Joaquin de Olmedo

Mon 12/15

12:49 am-10:08 am

1 stop9h 19m

$369

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/16

10:54 am-10:42 pm

1 stop11h 48m

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

3:31 pm-10:24 am

1 stop18h 53m

$652

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/16

6:36 am-10:42 pm

2 stops16h 06m

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

3:31 pm-10:24 am

1 stop18h 53m

$657

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Thu 12/4

6:30 am-5:36 pm

2 stops35h 06m

Guayaquil Jose Joaquin de Olmedo

Mon 12/8

2:35 pm-11:44 pm

2 stops33h 09m

$670

DaytonGuayaquil

DAY - GYE

DAYGYE

Dayton

Sat 12/6

4:16 pm-7:20 am

2 stops39h 04m

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

4:30 pm-5:47 pm

2 stops25h 17m

$700

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Sun 5/3

12:05 pm-7:20 am

1 stop20h 15m

Guayaquil Jose Joaquin de Olmedo

Wed 5/6

4:00 pm-11:41 am

1 stop18h 41m

$703

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Sun 5/3

6:45 am-5:35 pm

2 stops11h 50m

Guayaquil Jose Joaquin de Olmedo

Wed 5/6

2:35 pm-9:54 am

2 stops18h 19m

$716

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Ohio to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $496. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $1,250.

Cheap Ohio to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Guayaquil

Direct flights

None
There are no direct flights from Ohio to Guayaquil. There are no popular flight routes from Ohio to Guayaquil.
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  • When did momondo last update prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Guayaquil

Compare and see reviews for airlines that fly from Ohio to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $682Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Guayaquil?

It is quick and easy to find Ohio to Guayaquil flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guayaquil that suits you.

Can I find flights from Ohio to Guayaquil with flexible booking policies on momondo?

All flight searches from Ohio to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Ohio to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Guayaquil.

I’m not ready to book a flight from Ohio to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Ohio and alert you when they change.

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