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Cheap flights from Ohio to Guayaquil from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Guayaquil departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Ohio to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:09 am - 11:04 pm
DTW
-
GYE
18h 55m
2 stops
Spirit Airlines Logo
11:59 pm - 3:12 pm
GYE
-
DTW
14h 13m
1 stop
$299Spirit Airlines
Mon, Mar 9 - Mon, Mar 16
Spirit Airlines Logo
8:49 am - 11:04 pm
DTW
-
GYE
15h 15m
1 stop
Spirit Airlines Logo
11:59 pm - 3:12 pm
GYE
-
DTW
14h 13m
1 stop
$304Spirit Airlines
Mon, Mar 9 - Mon, Mar 16
Spirit Airlines Logo
5:09 am - 11:04 pm
DTW
-
GYE
18h 55m
2 stops
Spirit Airlines Logo
11:59 pm - 3:50 pm
GYE
-
DTW
14h 51m
2 stops
$305Spirit Airlines
Mon, Mar 9 - Mon, Mar 16
Multiple Airlines Logo
11:48 am - 11:04 pm
CVG
-
GYE
12h 16m
1 stop
Multiple Airlines Logo
11:59 pm - 6:31 pm
GYE
-
CVG
41h 32m
2 stops
$332Multiple Airlines
Sun, Mar 8 - Thu, Mar 12
Multiple Airlines Logo
6:45 pm - 11:04 pm
CLE
-
GYE
29h 19m
1 stop
Multiple Airlines Logo
11:59 pm - 5:13 pm
GYE
-
CLE
16h 14m
1 stop
$342Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
United Airlines Logo
6:45 pm - 5:31 pm
CVG
-
GYE
23h 46m
2 stops
United Airlines Logo
12:22 pm - 11:30 pm
GYE
-
CVG
34h 08m
2 stops
$640United Airlines
Sat, Apr 4 - Sun, Apr 12
United Airlines Logo
6:25 am - 5:33 pm
CVG
-
GYE
36h 08m
2 stops
United Airlines Logo
2:35 pm - 10:57 am
GYE
-
CVG
43h 22m
2 stops
$649United Airlines
Sun, Mar 8 - Sun, Mar 15
American Airlines Logo
6:31 pm - 1:31 pm
CAK
-
GYE
20h 00m
2 stops
American Airlines Logo
2:31 pm - 6:01 pm
GYE
-
CAK
26h 30m
2 stops
$669American Airlines
Fri, May 1 - Fri, May 8
LATAM Airlines Logo
7:00 am - 1:40 am
CLE
-
GYE
19h 40m
2 stops
LATAM Airlines Logo
8:45 pm - 6:47 pm
GYE
-
CLE
21h 02m
2 stops
$706LATAM Airlines
Thu, Jul 23 - Mon, Aug 17
American Airlines Logo
7:08 pm - 1:29 pm
CLE
-
GYE
19h 21m
1 stop
American Airlines Logo
8:00 am - 11:50 pm
GYE
-
CLE
14h 50m
1 stop
$707American Airlines
Thu, Jul 23 - Mon, Aug 17

Spirit Airlines flights from Ohio to Guayaquil

Our best Spirit Airlines deals on Ohio to Guayaquil flight tickets
Spirit Airlines
Mar 9
DTW5:09 amDetroit Metropolitan Wayne County
18h 55m
2 stops
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Mar 16
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
14h 13m
1 stop
DTW3:12 pmDetroit Metropolitan Wayne County
$299
Spirit Airlines
Mar 9
DTW8:49 amDetroit Metropolitan Wayne County
15h 15m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Mar 16
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
14h 13m
1 stop
DTW3:12 pmDetroit Metropolitan Wayne County
$304
Spirit Airlines
Mar 9
DTW5:09 amDetroit Metropolitan Wayne County
18h 55m
2 stops
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Mar 16
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
14h 51m
2 stops
DTW3:50 pmDetroit Metropolitan Wayne County
$305

United Airlines flights from Ohio to Guayaquil

Our best United Airlines deals on Ohio to Guayaquil flight tickets
United Airlines
Apr 4
CVG6:45 pmCincinnati Cinci./N. Kentucky
23h 46m
2 stops
GYE5:31 pmGuayaquil Jose Joaquin de Olmedo
Apr 12
GYE12:22 pmGuayaquil Jose Joaquin de Olmedo
34h 08m
2 stops
CVG11:30 pmCincinnati Cinci./N. Kentucky
$640
United Airlines
Mar 8
CVG6:25 amCincinnati Cinci./N. Kentucky
36h 08m
2 stops
GYE5:33 pmGuayaquil Jose Joaquin de Olmedo
Mar 15
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
43h 22m
2 stops
CVG10:57 amCincinnati Cinci./N. Kentucky
$649
United Airlines
Feb 26
CVG6:25 amCincinnati Cinci./N. Kentucky
14h 21m
2 stops
GYE8:46 pmGuayaquil Jose Joaquin de Olmedo
Mar 3
GYE12:20 pmGuayaquil Jose Joaquin de Olmedo
22h 32m
2 stops
CVG10:52 amCincinnati Cinci./N. Kentucky
$712

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 3/9

5:09 am-11:04 pm

2 stops18h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-3:12 pm

1 stop14h 13m

$299

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 3/9

8:49 am-11:04 pm

1 stop15h 15m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-3:12 pm

1 stop14h 13m

$304

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 3/9

5:09 am-11:04 pm

2 stops18h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-3:50 pm

2 stops14h 51m

$305

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Sun 3/8

11:48 am-11:04 pm

1 stop12h 16m

Guayaquil Jose Joaquin de Olmedo

Thu 3/12

11:59 pm-6:31 pm

2 stops41h 32m

$332

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Mon 3/23

6:45 pm-11:04 pm

1 stop29h 19m

Guayaquil Jose Joaquin de Olmedo

Mon 3/30

11:59 pm-5:13 pm

1 stop16h 14m

$342

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Sat 4/4

6:45 pm-5:31 pm

2 stops23h 46m

Guayaquil Jose Joaquin de Olmedo

Sun 4/12

12:22 pm-11:30 pm

2 stops34h 08m

$640

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Sun 3/8

6:25 am-5:33 pm

2 stops36h 08m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

2:35 pm-10:57 am

2 stops43h 22m

$649

AkronGuayaquil

CAK - GYE

CAKGYE

Akron/Canton

Fri 5/1

6:31 pm-1:31 pm

2 stops20h 00m

Guayaquil Jose Joaquin de Olmedo

Fri 5/8

2:31 pm-6:01 pm

2 stops26h 30m

$669

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 7/23

7:00 am-1:40 am

2 stops19h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

8:45 pm-6:47 pm

2 stops21h 02m

$706

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 7/23

7:08 pm-1:29 pm

1 stop19h 21m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

8:00 am-11:50 pm

1 stop14h 50m

$707

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Ohio to Guayaquil flights?

You could potentially save up to 42% on your flight if you consider stops on a Ohio to Guayaquil flight.

Cheap Ohio to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Guayaquil

Fastest flight time

12h 02m

Direct flights

None
The fastest flight from Ohio to Guayaquil takes 12h 02m
There are no direct flights from Ohio to Guayaquil. There are no popular flight routes from Ohio to Guayaquil.
Search flight deals

  • When did momondo last update prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Guayaquil

Compare and see reviews for airlines that fly from Ohio to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $655Free CancellationRating
7.2
11,248 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Guayaquil?

It is quick and easy to find Ohio to Guayaquil flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guayaquil that suits you.

Can I find flights from Ohio to Guayaquil with flexible booking policies on momondo?

All flight searches from Ohio to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Ohio to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Guayaquil.

I’m not ready to book a flight from Ohio to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Ohio and alert you when they change.

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