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Cheap flights from Ohio to Guayaquil from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Guayaquil departing on 8/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Ohio to Guayaquil

Cheap round-trip flights

Logo
6:41 am - 11:20 pmDTW-GYE
17h 39m2 stops
Logo
4:15 am - 11:29 pmGYE-DTW
18h 14m2 stops
$401
Find Deal
ter, set 30 - ter, out 14
Logo
6:28 am - 10:40 pmDTW-GYE
17h 12m2 stops
Logo
4:15 am - 11:43 pmGYE-DTW
18h 28m2 stops
$403
Find Deal
qua, ago 27 - qua, set 10
JetBlue Logo
6:12 am - 1:30 pmDTW-GYE
32h 18m2 stops
JetBlue Logo
9:30 pm - 11:30 amGYE-DTW
13h 00m1 stop
$548JetBlue
Find Deal
qua, set 24 - qua, out 8
JetBlue Logo
6:00 am - 5:28 amDTW-GYE
24h 28m1 stop
JetBlue Logo
2:40 pm - 9:07 pmGYE-DTW
29h 27m2 stops
$557JetBlue
Find Deal
ter, ago 26 - seg, set 8
LATAM Airlines Logo
3:29 pm - 7:20 amCMH-GYE
15h 51m1 stop
LATAM Airlines Logo
4:00 pm - 12:06 pmGYE-CMH
20h 06m1 stop
$574LATAM Airlines
Find Deal
qua, dez 24 - sáb, dez 27
American Airlines Logo
7:36 pm - 7:37 pmCLE-GYE
25h 01m2 stops
American Airlines Logo
8:20 am - 12:28 pmGYE-CLE
27h 08m2 stops
$579American Airlines
Find Deal
seg, set 1 - sex, set 12
United Airlines Logo
6:23 am - 11:37 pmCVG-GYE
18h 14m2 stops
United Airlines Logo
2:47 pm - 11:44 pmGYE-CVG
31h 57m2 stops
$587United Airlines
Find Deal
qua, ago 27 - qui, set 18
United Airlines Logo
7:00 am - 11:15 amCLE-GYE
29h 15m2 stops
United Airlines Logo
8:32 am - 11:27 amGYE-CLE
25h 55m2 stops
$587United Airlines
Find Deal
qui, ago 28 - seg, set 8
LATAM Airlines Logo
6:00 am - 6:53 amCMH-GYE
24h 53m2 stops
LATAM Airlines Logo
4:00 pm - 12:06 pmGYE-CMH
20h 06m1 stop
$594LATAM Airlines
Find Deal
qua, dez 24 - sáb, dez 27
American Airlines Logo
6:06 am - 7:48 pmDTW-GYE
14h 42m1 stop
American Airlines Logo
8:15 am - 11:40 pmGYE-DTW
14h 25m1 stop
$603American Airlines
Find Deal
ter, set 30 - ter, out 14

JetBlue flights from Ohio to Guayaquil

Our best JetBlue deals on Ohio to Guayaquil flight tickets
JetBlue
Sep 24
DTW6:12 amDetroit Metropolitan Wayne County
32h 18m
2 stops
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
Oct 8
GYE9:30 pmGuayaquil Jose Joaquin de Olmedo
13h 00m
1 stop
DTW11:30 amDetroit Metropolitan Wayne County
$548
Find similar
JetBlue
Aug 26
DTW6:00 amDetroit Metropolitan Wayne County
24h 28m
1 stop
GYE5:28 amGuayaquil Jose Joaquin de Olmedo
Sep 8
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
29h 27m
2 stops
DTW9:07 pmDetroit Metropolitan Wayne County
$557
Find similar
JetBlue
Sep 24
DTW6:12 amDetroit Metropolitan Wayne County
32h 18m
2 stops
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
Oct 1
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
24h 55m
2 stops
DTW4:35 pmDetroit Metropolitan Wayne County
$560
Find similar

American Airlines flights from Ohio to Guayaquil

Our best American Airlines deals on Ohio to Guayaquil flight tickets
American Airlines
Sep 1
CLE7:36 pmCleveland Hopkins Intl
25h 01m
2 stops
GYE7:37 pmGuayaquil Jose Joaquin de Olmedo
Sep 12
GYE8:20 amGuayaquil Jose Joaquin de Olmedo
27h 08m
2 stops
CLE12:28 pmCleveland Hopkins Intl
$579
Find similar
American Airlines
Sep 30
DTW6:06 amDetroit Metropolitan Wayne County
14h 42m
1 stop
GYE7:48 pmGuayaquil Jose Joaquin de Olmedo
Oct 14
GYE8:15 amGuayaquil Jose Joaquin de Olmedo
14h 25m
1 stop
DTW11:40 pmDetroit Metropolitan Wayne County
$603
Find similar
American Airlines
Aug 25
CLE8:04 pmCleveland Hopkins Intl
24h 33m
2 stops
GYE7:37 pmGuayaquil Jose Joaquin de Olmedo
Sep 4
GYE8:20 amGuayaquil Jose Joaquin de Olmedo
25h 15m
2 stops
CLE10:35 amCleveland Hopkins Intl
$619
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julho 31, 2025.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

ter 9/30

6:41 am-11:20 pm

2 stops17h 39m

Guayaquil Jose Joaquin de Olmedo

ter 10/14

4:15 am-11:29 pm

2 stops18h 14m

$401

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

qua 8/27

6:28 am-10:40 pm

2 stops17h 12m

Guayaquil Jose Joaquin de Olmedo

qua 9/10

4:15 am-11:43 pm

2 stops18h 28m

$403

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

qua 9/24

6:12 am-1:30 pm

2 stops32h 18m

Guayaquil Jose Joaquin de Olmedo

qua 10/8

9:30 pm-11:30 am

1 stop13h 00m

$548

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

ter 8/26

6:00 am-5:28 am

1 stop24h 28m

Guayaquil Jose Joaquin de Olmedo

seg 9/8

2:40 pm-9:07 pm

2 stops29h 27m

$557

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

qua 12/24

3:29 pm-7:20 am

1 stop15h 51m

Guayaquil Jose Joaquin de Olmedo

sáb 12/27

4:00 pm-12:06 pm

1 stop20h 06m

$574

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

seg 9/1

7:36 pm-7:37 pm

2 stops25h 01m

Guayaquil Jose Joaquin de Olmedo

sex 9/12

8:20 am-12:28 pm

2 stops27h 08m

$579

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

qua 8/27

6:23 am-11:37 pm

2 stops18h 14m

Guayaquil Jose Joaquin de Olmedo

qui 9/18

2:47 pm-11:44 pm

2 stops31h 57m

$587

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

qui 8/28

7:00 am-11:15 am

2 stops29h 15m

Guayaquil Jose Joaquin de Olmedo

seg 9/8

8:32 am-11:27 am

2 stops25h 55m

$587

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

qua 12/24

6:00 am-6:53 am

2 stops24h 53m

Guayaquil Jose Joaquin de Olmedo

sáb 12/27

4:00 pm-12:06 pm

1 stop20h 06m

$594

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

ter 9/30

6:06 am-7:48 pm

1 stop14h 42m

Guayaquil Jose Joaquin de Olmedo

ter 10/14

8:15 am-11:40 pm

1 stop14h 25m

$603

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Ohio to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $496. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $1,250.

Cheap Ohio to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Guayaquil

Best Price Found

$176

Fastest flight time

11h 50m

Direct flights

None

Airports in Guayaquil

1 airport
The best one-way flight to Guayaquil from Ohio in the past 72 hours is $176. The best round-trip flight deal from Ohio to Guayaquil found on momondo in the last 72 hours is $401.
The fastest flight from Ohio to Guayaquil takes 11h 50m
There are no direct flights from Ohio to Guayaquil. Popular non-direct routes for this connection are Columbus Airport - Guayaquil Jose Joaquin de Olmedo Airport, Cleveland Hopkins Intl Airport - Guayaquil Jose Joaquin de Olmedo Airport and Detroit Metropolitan Wayne County Airport - Guayaquil Jose Joaquin de Olmedo Airport.
There is 1 airport near Guayaquil: Guayaquil Jose Joaquin de Olmedo (GYE)
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  • When did momondo last update prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Guayaquil

Compare and see reviews for airlines that fly from Ohio to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $521Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Guayaquil?

It is quick and easy to find Ohio to Guayaquil flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guayaquil that suits you.

Can I find flights from Ohio to Guayaquil with flexible booking policies on momondo?

All flight searches from Ohio to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Ohio to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Guayaquil.

I’m not ready to book a flight from Ohio to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Ohio and alert you when they change.

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