Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Ohio to Guayaquil from $347

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Guayaquil departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Ohio to Guayaquil

Cheap round-trip flights

Multiple Airlines Logo
5:17 am - 4:20 amDTW-GYE
23h 03m1 stop
Multiple Airlines Logo
6:55 pm - 10:00 amGYE-DTW
39h 05m2 stops
$422Multiple Airlines
Find Deal
Sun, Nov 2 - Sun, Nov 9
JetBlue Logo
2:31 pm - 5:20 amDTW-GYE
14h 49m1 stop
JetBlue Logo
7:40 am - 10:57 pmGYE-DTW
15h 17m1 stop
$433JetBlue
Find Deal
Wed, Nov 19 - Wed, Feb 18
Multiple Airlines Logo
5:17 am - 4:20 amDTW-GYE
23h 03m1 stop
Multiple Airlines Logo
3:30 am - 10:00 amGYE-DTW
30h 30m2 stops
$441Multiple Airlines
Find Deal
Sun, Nov 2 - Sat, Nov 8
Spirit Airlines Logo
12:15 pm - 11:45 pmCLE-GYE
11h 30m1 stop
Spirit Airlines Logo
12:59 am - 11:20 amGYE-CLE
10h 21m1 stop
$473Spirit Airlines
Find Deal
Fri, Jan 23 - Fri, Jan 30
JetBlue Logo
2:31 pm - 4:20 amDTW-GYE
14h 49m1 stop
JetBlue Logo
7:20 am - 10:57 pmGYE-DTW
15h 37m1 stop
$530JetBlue
Find Deal
Sat, Nov 1 - Sun, Nov 9
American Airlines Logo
6:00 am - 7:10 pmDTW-GYE
14h 10m1 stop
American Airlines Logo
8:15 am - 11:18 amGYE-DTW
26h 03m2 stops
$561American Airlines
Find Deal
Tue, Oct 14 - Wed, Oct 22
American Airlines Logo
7:10 am - 7:10 pmDTW-GYE
13h 00m2 stops
American Airlines Logo
7:30 am - 9:01 amGYE-DTW
25h 31m2 stops
$575American Airlines
Find Deal
Tue, Oct 14 - Tue, Feb 10
United Airlines Logo
6:30 am - 1:34 pmCMH-GYE
31h 04m2 stops
United Airlines Logo
12:20 pm - 10:29 pmGYE-CMH
34h 09m2 stops
$636United Airlines
Find Deal
Thu, Nov 27 - Sun, Dec 7
United Airlines Logo
4:45 pm - 1:36 pmCMH-GYE
44h 51m2 stops
United Airlines Logo
2:35 pm - 7:15 pmGYE-CMH
28h 40m2 stops
$656United Airlines
Find Deal
Fri, Nov 28 - Sun, Dec 7
Spirit Airlines Logo
9:10 pm - 11:45 pmCMH-GYE
26h 35m2 stops
Spirit Airlines Logo
12:59 am - 9:55 amGYE-CMH
8h 56m1 stop
$756Spirit Airlines
Find Deal
Mon, Feb 16 - Sat, Feb 28

American Airlines flights from Ohio to Guayaquil

Our best American Airlines deals on Ohio to Guayaquil flight tickets
American Airlines
Oct 14
DTW6:00 amDetroit Metropolitan Wayne County
14h 10m
1 stop
GYE7:10 pmGuayaquil Jose Joaquin de Olmedo
Oct 22
GYE8:15 amGuayaquil Jose Joaquin de Olmedo
26h 03m
2 stops
DTW11:18 amDetroit Metropolitan Wayne County
$561
Find similar
American Airlines
Oct 14
DTW7:10 amDetroit Metropolitan Wayne County
13h 00m
2 stops
GYE7:10 pmGuayaquil Jose Joaquin de Olmedo
Feb 10
GYE7:30 amGuayaquil Jose Joaquin de Olmedo
25h 31m
2 stops
DTW9:01 amDetroit Metropolitan Wayne County
$575
Find similar
American Airlines
Jan 23
CLE5:23 amCleveland Hopkins Intl
16h 42m
2 stops
GYE10:05 pmGuayaquil Jose Joaquin de Olmedo
Jan 31
GYE7:30 amGuayaquil Jose Joaquin de Olmedo
15h 19m
2 stops
CLE10:49 pmCleveland Hopkins Intl
$579
Find similar

Avianca flights from Ohio to Guayaquil

Our best Avianca deals on Ohio to Guayaquil flight tickets
Avianca
Sep 29
CMH10:32 amColumbus
40h 33m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
Oct 20
GYE3:15 amGuayaquil Jose Joaquin de Olmedo
29h 29m
2 stops
CMH9:44 amColumbus
$669
Find similar
Avianca
Sep 29
CMH10:32 amColumbus
40h 33m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
Oct 21
GYE9:45 amGuayaquil Jose Joaquin de Olmedo
22h 59m
2 stops
CMH9:44 amColumbus
$739
Find similar
Avianca
Nov 27
CMH6:10 amColumbus
32h 15m
2 stops
GYE2:25 pmGuayaquil Jose Joaquin de Olmedo
Dec 6
GYE3:30 amGuayaquil Jose Joaquin de Olmedo
34h 38m
2 stops
CMH2:08 pmColumbus
$829
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 18, 2025.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/2

5:17 am-4:20 am

1 stop23h 03m

Guayaquil Jose Joaquin de Olmedo

Sun 11/9

6:55 pm-10:00 am

2 stops39h 05m

$422

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 11/19

2:31 pm-5:20 am

1 stop14h 49m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

7:40 am-10:57 pm

1 stop15h 17m

$433

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/2

5:17 am-4:20 am

1 stop23h 03m

Guayaquil Jose Joaquin de Olmedo

Sat 11/8

3:30 am-10:00 am

2 stops30h 30m

$441

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Fri 1/23

12:15 pm-11:45 pm

1 stop11h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

12:59 am-11:20 am

1 stop10h 21m

$473

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 11/1

2:31 pm-4:20 am

1 stop14h 49m

Guayaquil Jose Joaquin de Olmedo

Sun 11/9

7:20 am-10:57 pm

1 stop15h 37m

$530

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 10/14

6:00 am-7:10 pm

1 stop14h 10m

Guayaquil Jose Joaquin de Olmedo

Wed 10/22

8:15 am-11:18 am

2 stops26h 03m

$561

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 10/14

7:10 am-7:10 pm

2 stops13h 00m

Guayaquil Jose Joaquin de Olmedo

Tue 2/10

7:30 am-9:01 am

2 stops25h 31m

$575

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 11/27

6:30 am-1:34 pm

2 stops31h 04m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

12:20 pm-10:29 pm

2 stops34h 09m

$636

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 11/28

4:45 pm-1:36 pm

2 stops44h 51m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

2:35 pm-7:15 pm

2 stops28h 40m

$656

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/16

9:10 pm-11:45 pm

2 stops26h 35m

Guayaquil Jose Joaquin de Olmedo

Sat 2/28

12:59 am-9:55 am

1 stop8h 56m

$756

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Ohio to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Ohio to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $496. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $1,250.

Cheap Ohio to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Guayaquil

Direct flights

None
There are no direct flights from Ohio to Guayaquil. There are no popular flight routes from Ohio to Guayaquil.
Search flight deals

  • When did momondo last update prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Ohio to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Guayaquil

Compare and see reviews for airlines that fly from Ohio to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $521Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Guayaquil?

It is quick and easy to find Ohio to Guayaquil flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guayaquil that suits you.

Can I find flights from Ohio to Guayaquil with flexible booking policies on momondo?

All flight searches from Ohio to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Ohio to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Guayaquil.

I’m not ready to book a flight from Ohio to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Ohio and alert you when they change.

An easier way to manage your Guayaquil trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 10/18
Sat 10/25
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Ecuador