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Cheap flights from Chicago O'Hare Intl Airport to Lyon from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Lyon departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to Lyon

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
11:25 am - 5:50 pm
ORD
-
LYS
23h 25m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$615Turkish Airlines
Mon, Apr 27 - Tue, May 5
TAP AIR PORTUGAL Logo
6:00 pm - 5:45 pm
ORD
-
LYS
16h 45m
1 stop
TAP AIR PORTUGAL Logo
6:05 am - 4:05 pm
LYS
-
ORD
17h 00m
1 stop
$625TAP AIR PORTUGAL
Sun, May 3 - Sat, May 16
Turkish Airlines Logo
11:25 am - 9:25 am
ORD
-
LYS
15h 00m
1 stop
Turkish Airlines Logo
10:25 am - 9:40 am
LYS
-
ORD
30h 15m
1 stop
$630Turkish Airlines
Sun, Apr 5 - Tue, Apr 21
Turkish Airlines Logo
11:25 am - 9:15 am
ORD
-
LYS
14h 50m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$648Turkish Airlines
Fri, Apr 17 - Fri, May 22
TAP AIR PORTUGAL Logo
6:00 pm - 5:45 pm
ORD
-
LYS
16h 45m
1 stop
TAP AIR PORTUGAL Logo
6:45 pm - 4:00 pm
LYS
-
ORD
28h 15m
1 stop
$650TAP AIR PORTUGAL
Sun, May 3 - Sat, May 16
Turkish Airlines Logo
8:10 pm - 9:15 am
ORD
-
LYS
30h 05m
1 stop
Turkish Airlines Logo
10:25 am - 9:40 am
LYS
-
ORD
30h 15m
1 stop
$662Turkish Airlines
Thu, Apr 16 - Thu, Apr 23
Turkish Airlines Logo
11:25 am - 5:50 pm
ORD
-
LYS
23h 25m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$668Turkish Airlines
Mon, Apr 27 - Sun, May 10
Turkish Airlines Logo
11:25 am - 5:50 pm
ORD
-
LYS
23h 25m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$676Turkish Airlines
Sun, Apr 19 - Sat, Apr 25
Turkish Airlines Logo
8:10 pm - 9:25 am
ORD
-
LYS
30h 15m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$679Turkish Airlines
Thu, Apr 9 - Mon, Apr 13
Turkish Airlines Logo
11:25 am - 9:15 am
ORD
-
LYS
14h 50m
1 stop
Turkish Airlines Logo
6:50 pm - 9:40 am
LYS
-
ORD
21h 50m
1 stop
$689Turkish Airlines
Fri, Apr 17 - Fri, Apr 24

American Airlines flights from Chicago O'Hare Intl Airport to Lyon

Our best American Airlines deals on Chicago O'Hare Intl Airport to Lyon flight tickets
American Airlines
Apr 27
ORD5:45 pmChicago O'Hare Intl
17h 15m
2 stops
LYS6:00 pmLyon-Saint Exupéry
May 5
LYS6:10 amLyon-Saint Exupéry
15h 15m
1 stop
ORD2:25 pmChicago O'Hare Intl
$782
American Airlines
Apr 27
ORD5:45 pmChicago O'Hare Intl
17h 15m
2 stops
LYS6:00 pmLyon-Saint Exupéry
May 10
LYS6:10 amLyon-Saint Exupéry
15h 15m
1 stop
ORD2:25 pmChicago O'Hare Intl
$832
American Airlines
May 11
ORD5:55 pmChicago O'Hare Intl
17h 05m
1 stop
LYS6:00 pmLyon-Saint Exupéry
May 20
LYS6:10 amLyon-Saint Exupéry
17h 54m
2 stops
ORD5:04 pmChicago O'Hare Intl
$844

Lufthansa flights from Chicago O'Hare Intl Airport to Lyon

Our best Lufthansa deals on Chicago O'Hare Intl Airport to Lyon flight tickets
Lufthansa
May 7
ORD9:40 pmChicago O'Hare Intl
12h 25m
1 stop
LYS5:05 pmLyon-Saint Exupéry
May 14
LYS6:35 amLyon-Saint Exupéry
13h 20m
1 stop
ORD12:55 pmChicago O'Hare Intl
$787
Lufthansa
May 11
ORD3:35 pmChicago O'Hare Intl
13h 45m
1 stop
LYS12:20 pmLyon-Saint Exupéry
May 25
LYS5:50 pmLyon-Saint Exupéry
26h 05m
2 stops
ORD12:55 pmChicago O'Hare Intl
$823
Lufthansa
May 4
ORD3:35 pmChicago O'Hare Intl
18h 30m
1 stop
LYS5:05 pmLyon-Saint Exupéry
May 18
LYS5:50 pmLyon-Saint Exupéry
26h 05m
2 stops
ORD12:55 pmChicago O'Hare Intl
$834

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Lyon that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Mon 4/27

11:25 am-5:50 pm

1 stop23h 25m

Lyon-Saint Exupéry

Tue 5/5

6:50 pm-9:40 am

1 stop21h 50m

$615
Quickest round-trip

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 5/3

6:00 pm-5:45 pm

1 stop16h 45m

Lyon-Saint Exupéry

Sat 5/16

6:05 am-4:05 pm

1 stop17h 00m

$625

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 4/5

11:25 am-9:25 am

1 stop15h 00m

Lyon-Saint Exupéry

Tue 4/21

10:25 am-9:40 am

1 stop30h 15m

$630

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Fri 4/17

11:25 am-9:15 am

1 stop14h 50m

Lyon-Saint Exupéry

Fri 5/22

6:50 pm-9:40 am

1 stop21h 50m

$648

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 5/3

6:00 pm-5:45 pm

1 stop16h 45m

Lyon-Saint Exupéry

Sat 5/16

6:45 pm-4:00 pm

1 stop28h 15m

$650

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Thu 4/16

8:10 pm-9:15 am

1 stop30h 05m

Lyon-Saint Exupéry

Thu 4/23

10:25 am-9:40 am

1 stop30h 15m

$662

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Mon 4/27

11:25 am-5:50 pm

1 stop23h 25m

Lyon-Saint Exupéry

Sun 5/10

6:50 pm-9:40 am

1 stop21h 50m

$668

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 4/19

11:25 am-5:50 pm

1 stop23h 25m

Lyon-Saint Exupéry

Sat 4/25

6:50 pm-9:40 am

1 stop21h 50m

$676

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Thu 4/9

8:10 pm-9:25 am

1 stop30h 15m

Lyon-Saint Exupéry

Mon 4/13

6:50 pm-9:40 am

1 stop21h 50m

$679

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Fri 4/17

11:25 am-9:15 am

1 stop14h 50m

Lyon-Saint Exupéry

Fri 4/24

6:50 pm-9:40 am

1 stop21h 50m

$689

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Lyon from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Lyon

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Lyon?

If you aren’t able to travel during the month of February, then book flights to Lyon from Chicago O'Hare Intl Airport during January instead. Flights to Lyon in January, while not as cheap as those in February, still average around $683.

When to book flights from Chicago O'Hare Intl Airport to Lyon

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Lyon according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Lyon (ORD to LYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Lyon

Fastest flight time

12h 25m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Lyon takes 12h 25m
There are no direct flights from Chicago O'Hare Intl Airport to Lyon. There are no popular flight routes from Chicago O'Hare Intl Airport to Lyon.
Search flight deals

  • How far is Chicago O'Hare Intl to Lyon-Saint Exupéry by plane?

    The straight-line distance from Chicago O'Hare Intl to Lyon-Saint Exupéry is 4348.1 mi. A reasonable flight in good conditions will take 12h 25m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport.

  • What documentation or ID do you need to fly to Lyon-Saint Exupéry Airport?

    The travel and health documents you'll need for your trip to Lyon-Saint Exupéry Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lyon-Saint Exupéry Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Lyon?

Best airlines flying from Chicago O'Hare Intl Airport to Lyon

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Lyon with momondo
Airline
Rating
Free Cancellation
Price
Scandinavian AirlinesPriceFrom $592Free CancellationRating
7.3
1,722 reviews
Search Scandinavian Airlines flights
United AirlinesPriceFrom $704Free CancellationRating
7.4
9,470 reviews
Search United Airlines flights

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Chamonix
Courchevel
Val Thorens
Val-d'Isere
Megève
Ferney-Voltaire
Morzine
Évian-les-Bains
Les Houches
Annemasse
Saint-Gervais-les-Bains
Vienne
Lons-le-Saunier
Gap
Albertville
Aubenas
Tignes
Val-Cenis
Aix-les-Bains
Tournus

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Lyon?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Lyon. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Lyon with flexible booking policies on momondo?

All flight searches from Chicago to Lyon on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Lyon?

momondo helps you find the best flight between Chicago and Lyon by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Lyon right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Lyon flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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