Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Lyon from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Lyon departing on 3/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Lyon

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:45 am - 12:20 pm
ORD
-
LYS
20h 35m
2 stops
Multiple Airlines Logo
2:35 pm - 7:55 pm
LYS
-
ORD
12h 20m
1 stop
$550Multiple Airlines
Wed, May 6 - Fri, May 15
Lufthansa Logo
10:30 pm - 5:50 pm
ORD
-
LYS
12h 20m
1 stop
Lufthansa Logo
7:05 am - 12:55 pm
LYS
-
ORD
12h 50m
1 stop
$551Lufthansa
Wed, May 6 - Fri, May 15
Delta Logo
11:08 am - 9:30 am
ORD
-
LYS
15h 22m
2 stops
Delta Logo
9:55 am - 2:15 pm
LYS
-
ORD
11h 20m
1 stop
$566Delta
Wed, May 6 - Fri, May 15
TAP AIR PORTUGAL Logo
7:10 pm - 5:35 pm
ORD
-
LYS
15h 25m
1 stop
TAP AIR PORTUGAL Logo
5:10 am - 2:45 pm
LYS
-
ORD
16h 35m
1 stop
$577TAP AIR PORTUGAL
Wed, Mar 4 - Sun, Mar 8
Delta Logo
3:30 pm - 1:45 pm
ORD
-
LYS
15h 15m
2 stops
Delta Logo
6:00 am - 6:13 pm
LYS
-
ORD
19h 13m
2 stops
$585Delta
Wed, May 6 - Fri, May 15
Delta Logo
3:30 pm - 1:45 pm
ORD
-
LYS
15h 15m
2 stops
Delta Logo
6:00 am - 6:13 pm
LYS
-
ORD
19h 13m
2 stops
$586Delta
Wed, May 6 - Fri, May 15
Multiple Airlines Logo
12:50 pm - 11:40 am
ORD
-
LYS
15h 50m
1 stop
Multiple Airlines Logo
6:55 am - 7:55 pm
LYS
-
ORD
20h 00m
1 stop
$593Multiple Airlines
Sun, Apr 19 - Tue, May 12
Lufthansa Logo
4:05 pm - 9:55 am
ORD
-
LYS
10h 50m
1 stop
Lufthansa Logo
2:35 pm - 7:55 pm
LYS
-
ORD
12h 20m
1 stop
$595Lufthansa
Wed, May 6 - Fri, May 15
Lufthansa Logo
4:05 pm - 9:55 am
ORD
-
LYS
10h 50m
1 stop
Lufthansa Logo
2:45 pm - 7:55 pm
LYS
-
ORD
12h 10m
1 stop
$596Lufthansa
Mon, Apr 20 - Tue, Apr 28
United Airlines Logo
12:50 pm - 11:40 am
ORD
-
LYS
15h 50m
1 stop
United Airlines Logo
2:05 pm - 12:00 pm
LYS
-
ORD
28h 55m
2 stops
$599United Airlines
Sun, Apr 19 - Tue, May 12

United Airlines flights from Chicago O'Hare Intl Airport to Lyon

Our best United Airlines deals on Chicago O'Hare Intl Airport to Lyon flight tickets
United Airlines
Apr 19
ORD12:50 pmChicago O'Hare Intl
15h 50m
1 stop
LYS11:40 amLyon-Saint Exupéry
May 12
LYS2:05 pmLyon-Saint Exupéry
28h 55m
2 stops
ORD12:00 pmChicago O'Hare Intl
$599
United Airlines
Apr 19
ORD11:15 amChicago O'Hare Intl
17h 25m
2 stops
LYS11:40 amLyon-Saint Exupéry
May 12
LYS2:05 pmLyon-Saint Exupéry
28h 55m
2 stops
ORD12:00 pmChicago O'Hare Intl
$604
United Airlines
May 6
ORD1:55 pmChicago O'Hare Intl
15h 25m
2 stops
LYS12:20 pmLyon-Saint Exupéry
May 15
LYS2:05 pmLyon-Saint Exupéry
30h 10m
2 stops
ORD1:15 pmChicago O'Hare Intl
$608

Delta flights from Chicago O'Hare Intl Airport to Lyon

Our best Delta deals on Chicago O'Hare Intl Airport to Lyon flight tickets
Delta
May 6
ORD11:08 amChicago O'Hare Intl
15h 22m
2 stops
LYS9:30 amLyon-Saint Exupéry
May 15
LYS9:55 amLyon-Saint Exupéry
11h 20m
1 stop
ORD2:15 pmChicago O'Hare Intl
$566
Delta
May 6
ORD3:30 pmChicago O'Hare Intl
15h 15m
2 stops
LYS1:45 pmLyon-Saint Exupéry
May 15
LYS6:00 amLyon-Saint Exupéry
19h 13m
2 stops
ORD6:13 pmChicago O'Hare Intl
$585
Delta
May 6
ORD3:30 pmChicago O'Hare Intl
15h 15m
2 stops
LYS1:45 pmLyon-Saint Exupéry
May 15
LYS6:00 amLyon-Saint Exupéry
19h 13m
2 stops
ORD6:13 pmChicago O'Hare Intl
$586

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Lyon that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

8:45 am-12:20 pm

2 stops20h 35m

Lyon-Saint Exupéry

Fri 5/15

2:35 pm-7:55 pm

1 stop12h 20m

$550

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

10:30 pm-5:50 pm

1 stop12h 20m

Lyon-Saint Exupéry

Fri 5/15

7:05 am-12:55 pm

1 stop12h 50m

$551

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

11:08 am-9:30 am

2 stops15h 22m

Lyon-Saint Exupéry

Fri 5/15

9:55 am-2:15 pm

1 stop11h 20m

$566

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 3/4

7:10 pm-5:35 pm

1 stop15h 25m

Lyon-Saint Exupéry

Sun 3/8

5:10 am-2:45 pm

1 stop16h 35m

$577

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

3:30 pm-1:45 pm

2 stops15h 15m

Lyon-Saint Exupéry

Fri 5/15

6:00 am-6:13 pm

2 stops19h 13m

$585

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

3:30 pm-1:45 pm

2 stops15h 15m

Lyon-Saint Exupéry

Fri 5/15

6:00 am-6:13 pm

2 stops19h 13m

$586

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 4/19

12:50 pm-11:40 am

1 stop15h 50m

Lyon-Saint Exupéry

Tue 5/12

6:55 am-7:55 pm

1 stop20h 00m

$593

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 5/6

4:05 pm-9:55 am

1 stop10h 50m

Lyon-Saint Exupéry

Fri 5/15

2:35 pm-7:55 pm

1 stop12h 20m

$595

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Mon 4/20

4:05 pm-9:55 am

1 stop10h 50m

Lyon-Saint Exupéry

Tue 4/28

2:45 pm-7:55 pm

1 stop12h 10m

$596

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 4/19

12:50 pm-11:40 am

1 stop15h 50m

Lyon-Saint Exupéry

Tue 5/12

2:05 pm-12:00 pm

2 stops28h 55m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Lyon from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Lyon

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Which airport is the most popular layover for flights between Chicago O'Hare Intl Airport and Lyon?

Percentage of 1-stop return trips between Chicago O'Hare Intl Airport and Lyon selected by momondo users, with the same layover airport each way, over the last 12 months.

Montreal (YUL) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Chicago O'Hare Intl Airport to Lyon?

Average price of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Lyon, with the same layover airport on both legs, clicked by momondo users over the past 12 months.

Flights via Paris (CDG) offer the lowest average round-trip price of $1,041.

Which layover airport has the shortest travel time from Chicago O'Hare Intl Airport to Lyon?

Average total travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Lyon, grouped by layover airport, based on momondo user clicks from the past 12 months.

Flights connecting via Paris (CDG) have the shortest average one-way travel time: 10h 15m.

Which layover airport has the shortest connection time from Chicago O'Hare Intl Airport to Lyon?

Average connection time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Lyon, grouped by layover airport, based on momondo user clicks over the last 12 months.

Paris (CDG) has the shortest average layover time for this route: 1h 23m.

When to book flights from Chicago O'Hare Intl Airport to Lyon

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Lyon according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Lyon (ORD to LYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Lyon

Fastest flight time

10h 50m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Lyon takes 10h 50m
There are no direct flights from Chicago O'Hare Intl Airport to Lyon. There are no popular flight routes from Chicago O'Hare Intl Airport to Lyon.
Search flight deals

  • How far is Chicago O'Hare Intl to Lyon-Saint Exupéry by plane?

    The straight-line distance from Chicago O'Hare Intl to Lyon-Saint Exupéry is 4348.1 mi. A reasonable flight in good conditions will take 10h 50m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Lyon-Saint Exupéry Airport.

  • What documentation or ID do you need to fly to Lyon-Saint Exupéry Airport?

    The travel and health documents you'll need for your trip to Lyon-Saint Exupéry Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lyon-Saint Exupéry Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Lyon?

Best airlines flying from Chicago O'Hare Intl Airport to Lyon

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Lyon with momondo
Airline
Rating
Free Cancellation
Price
Scandinavian AirlinesPriceFrom $592Free CancellationRating
7.3
1,678 reviews
Search Scandinavian Airlines flights
United AirlinesPriceFrom $704Free CancellationRating
7.4
9,254 reviews
Search United Airlines flights

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Chamonix
Courchevel
Val Thorens
Ferney-Voltaire
Megève
Val-d'Isere
Morzine
Évian-les-Bains
Les Houches
Annemasse
Saint-Gervais-les-Bains
Vienne
Tignes
Lons-le-Saunier
Gap
Aubenas
Val-Cenis
Albertville
Tournus
Huez

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Lyon?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Lyon. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Lyon with flexible booking policies on momondo?

All flight searches from Chicago to Lyon on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Lyon?

momondo helps you find the best flight between Chicago and Lyon by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Lyon right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Lyon flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Lyon trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 3/10
Tue 3/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to France