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Cheap flights from North Carolina to Panama City from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama City departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from North Carolina to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:38 pm - 2:00 pmCLT-PTY
16h 22m2 stops
Multiple Airlines Logo
5:55 pm - 8:49 amPTY-CLT
14h 54m2 stops
$388Multiple Airlines
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Thu, Nov 13 - Thu, Nov 20
Multiple Airlines Logo
9:38 pm - 8:50 amCLT-PTY
11h 12m2 stops
Multiple Airlines Logo
2:55 pm - 1:00 pmPTY-CLT
22h 05m2 stops
$389Multiple Airlines
Find Deal
Thu, Nov 6 - Mon, Nov 10
United Airlines Logo
6:45 am - 5:07 pmCLT-PTY
10h 22m1 stop
United Airlines Logo
8:55 am - 9:42 pmPTY-CLT
12h 47m1 stop
$400United Airlines
Find Deal
Mon, Dec 15 - Wed, Dec 24
American Airlines Logo
6:10 am - 1:27 pmORF-PTY
7h 17m1 stop
American Airlines Logo
2:27 pm - 10:59 pmPTY-ORF
8h 32m1 stop
$404American Airlines
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Thu, Jan 29 - Tue, Feb 3
American Airlines Logo
8:19 pm - 1:43 pmCLT-PTY
17h 24m1 stop
American Airlines Logo
4:43 pm - 6:29 amPTY-CLT
13h 46m2 stops
$404American Airlines
Find Deal
Mon, Dec 1 - Thu, Dec 4
United Airlines Logo
6:05 am - 8:02 pmORF-PTY
13h 57m2 stops
United Airlines Logo
4:41 pm - 2:07 pmPTY-ORF
21h 26m2 stops
$408United Airlines
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Thu, Jan 29 - Tue, Feb 3
Copa Airlines Logo
3:14 pm - 7:46 pmRDU-PTY
4h 32mnonstop
Copa Airlines Logo
8:57 am - 1:27 pmPTY-RDU
4h 30mnonstop
$441Copa Airlines
Find Deal
Mon, Nov 24 - Fri, Nov 28
Delta Logo
10:53 am - 12:55 pmFAY-PTY
27h 02m1 stop
Delta Logo
2:20 pm - 10:56 pmPTY-FAY
7h 36m1 stop
$443Delta
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Mon, Apr 6 - Thu, Apr 9
Delta Logo
6:35 am - 2:12 pmORF-PTY
7h 37m1 stop
Delta Logo
8:05 am - 4:17 pmPTY-ORF
8h 12m1 stop
$444Delta
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Sat, Nov 15 - Sat, Nov 22
Copa Airlines Logo
3:09 pm - 7:46 pmRDU-PTY
4h 37mnonstop
Copa Airlines Logo
8:57 am - 1:14 pmPTY-RDU
4h 17mnonstop
$471Copa Airlines
Find Deal
Fri, Jan 30 - Sun, Feb 8

United Airlines flights from North Carolina to Panama City

Our best United Airlines deals on North Carolina to Panama City flight tickets
United Airlines
Dec 15
CLT6:45 amCharlotte Douglas
10h 22m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Dec 24
PTY8:55 amPanama City Tocumen Intl
12h 47m
1 stop
CLT9:42 pmCharlotte Douglas
$400
Find similar
United Airlines
Dec 15
CLT6:45 amCharlotte Douglas
12h 53m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Dec 22
PTY4:41 pmPanama City Tocumen Intl
29h 01m
1 stop
CLT9:42 pmCharlotte Douglas
$408
Find similar
United Airlines
Dec 14
CLT6:45 amCharlotte Douglas
12h 53m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Dec 22
PTY11:35 amPanama City Tocumen Intl
10h 07m
1 stop
CLT9:42 pmCharlotte Douglas
$420
Find similar

Copa Airlines flights from North Carolina to Panama City

Our best Copa Airlines deals on North Carolina to Panama City flight tickets
Copa Airlines
Nov 24
RDU3:14 pmRaleigh-Durham
4h 32m
PTY7:46 pmPanama City Tocumen Intl
Nov 28
PTY8:57 amPanama City Tocumen Intl
4h 30m
RDU1:27 pmRaleigh-Durham
$441
Find similar
Copa Airlines
Jan 30
RDU3:09 pmRaleigh-Durham
4h 37m
PTY7:46 pmPanama City Tocumen Intl
Feb 8
PTY8:57 amPanama City Tocumen Intl
4h 17m
RDU1:14 pmRaleigh-Durham
$471
Find similar
Copa Airlines
Nov 7
RDU3:14 pmRaleigh-Durham
4h 32m
PTY7:46 pmPanama City Tocumen Intl
Nov 9
PTY8:57 amPanama City Tocumen Intl
4h 30m
RDU1:27 pmRaleigh-Durham
$518
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momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/13

9:38 pm-2:00 pm

2 stops16h 22m

Panama City Tocumen Intl

Thu 11/20

5:55 pm-8:49 am

2 stops14h 54m

$388

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/6

9:38 pm-8:50 am

2 stops11h 12m

Panama City Tocumen Intl

Mon 11/10

2:55 pm-1:00 pm

2 stops22h 05m

$389

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/15

6:45 am-5:07 pm

1 stop10h 22m

Panama City Tocumen Intl

Wed 12/24

8:55 am-9:42 pm

1 stop12h 47m

$400

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 1/29

6:10 am-1:27 pm

1 stop7h 17m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-10:59 pm

1 stop8h 32m

$404

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/1

8:19 pm-1:43 pm

1 stop17h 24m

Panama City Tocumen Intl

Thu 12/4

4:43 pm-6:29 am

2 stops13h 46m

$404

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 1/29

6:05 am-8:02 pm

2 stops13h 57m

Panama City Tocumen Intl

Tue 2/3

4:41 pm-2:07 pm

2 stops21h 26m

$408

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 11/24

3:14 pm-7:46 pm

Nonstop4h 32m

Panama City Tocumen Intl

Fri 11/28

8:57 am-1:27 pm

Nonstop4h 30m

$441

FayettevillePanama City

FAY - PTY

FAYPTY

Fayetteville

Mon 4/6

10:53 am-12:55 pm

1 stop27h 02m

Panama City Tocumen Intl

Thu 4/9

2:20 pm-10:56 pm

1 stop7h 36m

$443

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Sat 11/15

6:35 am-2:12 pm

1 stop7h 37m

Panama City Tocumen Intl

Sat 11/22

8:05 am-4:17 pm

1 stop8h 12m

$444

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/30

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

Sun 2/8

8:57 am-1:14 pm

Nonstop4h 17m

$471

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from North Carolina to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, November is the cheapest month to fly from North Carolina to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $306. If you’re not able to fly to Panama City in November, then October is your next best option. Flight prices from North Carolina to Panama City during October average around $398.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $336. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $743. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from North Carolina to Panama City during this time can be as low as $413. Try not to purchase tickets in the morning because they tend to be around $553. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest North Carolina to Panama City Tocumen Intl flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best North Carolina - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $471 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from North Carolina for as low as $420 on momondo.

What cabin class options are available on North Carolina to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on North Carolina to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Panama City flights?

You could potentially save up to 68% on your flight if you consider stops on a North Carolina to Panama City flight.

Cheap North Carolina to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama City

Best Price Found

$178

Fastest flight time

4h 27m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from North Carolina in the past 72 hours is $178. The best round-trip flight deal from North Carolina to Panama City found on momondo in the last 72 hours is $338.
The fastest flight from North Carolina to Panama City takes 4h 27m
Direct flights go from North Carolina to Panama City on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from North Carolina to Panama City Tocumen Intl Airport?

    Prices for flights from North Carolina to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from North Carolina to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from North Carolina to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from North Carolina to Panama City?

Best airlines flying from North Carolina to Panama City

Compare and see reviews for airlines that fly from North Carolina to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $282Free CancellationRating
7.6
1,551 reviews
Search Copa Airlines flights
DeltaPriceFrom $357Free CancellationRating
7.9
7,978 reviews
Search Delta flights
United AirlinesPriceFrom $409Free CancellationRating
7.4
8,982 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Panama City for you.

Can I find flights from North Carolina to Panama City with flexible booking policies on momondo?

All flight searches from North Carolina to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from North Carolina to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from North Carolina.

I’m not ready to book a flight from North Carolina to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from North Carolina and alert you when they change.

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