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Cheap flights from North Carolina to Panama City from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama City departing on 2/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from North Carolina to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
12:09 pm - 7:31 pm
GSO
-
PTY
8h 22m
1 stop
United Airlines Logo
9:45 am - 9:50 pm
PTY
-
GSO
11h 05m
1 stop
$415United Airlines
Wed, Apr 22 - Mon, Apr 27
United Airlines Logo
6:00 am - 7:38 pm
ORF
-
PTY
13h 38m
1 stop
United Airlines Logo
10:00 am - 7:00 pm
PTY
-
ORF
9h 00m
1 stop
$425United Airlines
Tue, Feb 3 - Thu, Feb 5
Multiple Airlines Logo
6:00 am - 8:02 pm
ORF
-
PTY
14h 02m
1 stop
Multiple Airlines Logo
10:55 pm - 11:54 am
PTY
-
ORF
11h 59m
1 stop
$431Multiple Airlines
Wed, Feb 25 - Tue, Apr 21
Multiple Airlines Logo
7:00 am - 1:00 am
CLT
-
PTY
19h 00m
2 stops
Multiple Airlines Logo
5:50 pm - 12:19 pm
PTY
-
CLT
17h 29m
2 stops
$451Multiple Airlines
Sun, Mar 8 - Mon, Mar 16
American Airlines Logo
7:05 pm - 3:15 pm
ORF
-
PTY
20h 10m
2 stops
American Airlines Logo
2:40 pm - 12:43 pm
PTY
-
ORF
22h 03m
2 stops
$454American Airlines
Thu, Feb 26 - Sun, Mar 1
American Airlines Logo
6:00 am - 12:36 pm
ILM
-
PTY
7h 36m
1 stop
American Airlines Logo
1:49 pm - 11:58 pm
PTY
-
ILM
9h 09m
1 stop
$457American Airlines
Tue, Apr 28 - Tue, May 5
Copa Airlines Logo
4:18 pm - 7:46 pm
RDU
-
PTY
4h 28mnonstop
Copa Airlines Logo
8:57 am - 2:29 pm
PTY
-
RDU
4h 32mnonstop
$462Copa Airlines
Wed, Apr 22 - Fri, Apr 24
Delta Logo
6:15 am - 1:03 pm
TRI
-
PTY
7h 48m
1 stop
Delta Logo
2:20 pm - 3:14 pm
PTY
-
TRI
23h 54m
1 stop
$463Delta
Tue, Mar 24 - Tue, Apr 21
Copa Airlines Logo
6:00 am - 7:31 pm
RDU
-
PTY
14h 31m
1 stop
Copa Airlines Logo
7:55 am - 10:06 pm
PTY
-
RDU
13h 11m
1 stop
$480Copa Airlines
Fri, May 22 - Tue, May 26
Delta Logo
6:00 am - 12:55 pm
ILM
-
PTY
7h 55m
1 stop
Delta Logo
2:20 pm - 9:44 am
PTY
-
ILM
18h 24m
1 stop
$484Delta
Tue, May 12 - Sat, May 16

American Airlines flights from North Carolina to Panama City

Our best American Airlines deals on North Carolina to Panama City flight tickets
American Airlines
Feb 26
ORF6:28 pmNorfolk
20h 47m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 1
PTY4:05 pmPanama City Tocumen Intl
21h 07m
2 stops
ORF1:12 pmNorfolk
$454
American Airlines
Apr 28
ILM6:00 amWilmington New Hanover County
7h 36m
1 stop
PTY12:36 pmPanama City Tocumen Intl
May 5
PTY1:49 pmPanama City Tocumen Intl
9h 09m
1 stop
ILM11:58 pmWilmington New Hanover County
$457
American Airlines
Apr 1
AVL4:43 pmAsheville Regional
20h 57m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Apr 7
PTY1:49 pmPanama City Tocumen Intl
22h 37m
2 stops
AVL1:26 pmAsheville Regional
$461

United Airlines flights from North Carolina to Panama City

Our best United Airlines deals on North Carolina to Panama City flight tickets
United Airlines
Apr 22
GSO12:09 pmGreensboro/H. Point
8h 22m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 27
PTY9:45 amPanama City Tocumen Intl
11h 05m
1 stop
GSO9:50 pmGreensboro/H. Point
$415
United Airlines
Feb 3
ORF6:00 amNorfolk
13h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 5
PTY10:00 amPanama City Tocumen Intl
9h 00m
1 stop
ORF7:00 pmNorfolk
$425
United Airlines
Feb 3
ORF6:00 amNorfolk
8h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 5
PTY11:35 amPanama City Tocumen Intl
11h 55m
2 stops
ORF11:30 pmNorfolk
$429

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Wed 4/22

12:09 pm-7:31 pm

1 stop8h 22m

Panama City Tocumen Intl

Mon 4/27

9:45 am-9:50 pm

1 stop11h 05m

$415

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Tue 2/3

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Thu 2/5

10:00 am-7:00 pm

1 stop9h 00m

$425

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 2/25

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Tue 4/21

10:55 pm-11:54 am

1 stop11h 59m

$431

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 3/8

7:00 am-1:00 am

2 stops19h 00m

Panama City Tocumen Intl

Mon 3/16

5:50 pm-12:19 pm

2 stops17h 29m

$451

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 2/26

7:05 pm-3:15 pm

2 stops20h 10m

Panama City Tocumen Intl

Sun 3/1

2:40 pm-12:43 pm

2 stops22h 03m

$454

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 4/28

6:00 am-12:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Tue 5/5

1:49 pm-11:58 pm

1 stop9h 09m

$457

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 4/22

4:18 pm-7:46 pm

Nonstop4h 28m

Panama City Tocumen Intl

Fri 4/24

8:57 am-2:29 pm

Nonstop4h 32m

$462

BlountvillePanama City

TRI - PTY

TRIPTY

Blountville Tri Cities TN/VA

Tue 3/24

6:15 am-1:03 pm

1 stop7h 48m

Panama City Tocumen Intl

Tue 4/21

2:20 pm-3:14 pm

1 stop23h 54m

$463

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 5/22

6:00 am-7:31 pm

1 stop14h 31m

Panama City Tocumen Intl

Tue 5/26

7:55 am-10:06 pm

1 stop13h 11m

$480

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 5/12

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sat 5/16

2:20 pm-9:44 am

1 stop18h 24m

$484

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from North Carolina to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from North Carolina to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $402. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from North Carolina to Panama City during September average around $417.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $346. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $738. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest North Carolina to Panama City Tocumen Intl flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best North Carolina - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $513 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from North Carolina for as low as $407 on momondo.

What cabin class options are available on North Carolina to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on North Carolina to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Panama City flights?

You could potentially save up to 68% on your flight if you consider stops on a North Carolina to Panama City flight.

Cheap North Carolina to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama City

Best Price Found

$183

Fastest flight time

4h 25m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from North Carolina in the past 72 hours is $183. The best round-trip flight deal from North Carolina to Panama City found on momondo in the last 72 hours is $293.
The fastest flight from North Carolina to Panama City takes 4h 25m
Direct flights go from North Carolina to Panama City on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Panama City. From North Carolina there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • When did momondo last update prices for flights from North Carolina to Panama City Tocumen Intl Airport?

    Prices for flights from North Carolina to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from North Carolina to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from North Carolina to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from North Carolina to Panama City?

Best airlines flying from North Carolina to Panama City

Compare and see reviews for airlines that fly from North Carolina to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,168 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $352Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
DeltaPriceFrom $367Free CancellationRating
7.9
8,087 reviews
Search Delta flights
United AirlinesPriceFrom $409Free CancellationRating
7.4
9,188 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Panama City for you.

Can I find flights from North Carolina to Panama City with flexible booking policies on momondo?

All flight searches from North Carolina to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from North Carolina to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from North Carolina.

I’m not ready to book a flight from North Carolina to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from North Carolina and alert you when they change.

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