Cheap flights from North Carolina to Panama from $245
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
RaleighPanama City
RDU Raleigh-Durham - PTY Panama City Tocumen Intl
RDUPTY
Raleigh-Durham
Wed 11/11
7:20 pm-6:55 pm
2 stops23h 35m
Panama City Tocumen Intl
Tue 11/17
3:50 pm-12:18 pm
2 stops20h 28m
RaleighPanama City
RDU Raleigh-Durham - PTY Panama City Tocumen Intl
RDUPTY
Raleigh-Durham
Thu 9/24
6:45 pm-10:30 am
2 stops16h 45m
Panama City Tocumen Intl
Mon 9/28
3:50 pm-12:33 pm
2 stops19h 43m
NorfolkPanama City
ORF Norfolk - PTY Panama City Tocumen Intl
ORFPTY
Norfolk
Wed 11/11
6:00 am-8:02 pm
1 stop14h 02m
Panama City Tocumen Intl
Mon 11/16
10:00 am-10:34 pm
1 stop12h 34m
NorfolkPanama City
ORF Norfolk - PTY Panama City Tocumen Intl
ORFPTY
Norfolk
Wed 11/11
6:00 am-8:02 pm
1 stop14h 02m
Panama City Tocumen Intl
Mon 11/16
10:00 am-10:34 pm
1 stop12h 34m
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 11/5
7:40 am-1:59 pm
1 stop6h 19m
Panama City Tocumen Intl
Tue 11/10
3:30 pm-11:54 pm
1 stop8h 24m
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 11/4
6:00 am-1:59 pm
1 stop7h 59m
Panama City Tocumen Intl
Mon 11/9
3:30 pm-11:54 pm
1 stop8h 24m
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 10/12
10:44 pm-1:02 pm
1 stop15h 18m
Panama City Tocumen Intl
Fri 10/16
2:02 pm-8:24 am
1 stop17h 22m
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 10/19
10:44 pm-1:02 pm
1 stop15h 18m
Panama City Tocumen Intl
Fri 10/23
2:02 pm-11:49 pm
1 stop8h 47m
NorfolkPanama City
ORF Norfolk - PTY Panama City Tocumen Intl
ORFPTY
Norfolk
Wed 10/7
6:00 am-7:31 pm
1 stop14h 31m
Panama City Tocumen Intl
Sun 10/11
3:30 pm-12:15 pm
2 stops19h 45m
NorfolkPanama City
ORF Norfolk - PTY Panama City Tocumen Intl
ORFPTY
Norfolk
Wed 10/7
6:20 am-6:37 pm
2 stops13h 17m
Panama City Tocumen Intl
Sun 10/11
3:30 pm-12:15 pm
2 stops19h 45m
See travel insights to Panama from
How to get the cheapest flight ticket from North Carolina to Panama
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Panama?
The month of October is, on average, the cheapest month to fly to Panama from North Carolina, with most prices found around $470. If you don’t want to visit Panama in October, then you should wait until April to fly from North Carolina, when ticket prices are also cheap, with an average price of $539.
What is the cheapest North Carolina to Panama flight route?
Fly from Raleigh-Durham to Panama City Tocumen Intl for the best North Carolina - Panama flight prices
How far in advance should I book a flight from North Carolina to Panama?
You are more likely to see cheaper flights to Panama from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $607 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from North Carolina for as low as $526 on momondo.
What cabin class options are available on North Carolina to Panama flights?
There are 3 cabin classes available to choose from on North Carolina to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from North Carolina to Panama?
United Airlines, Delta, and American Airlines are the most popular carriers operating from North Carolina to Panama
What airlines fly to Panama?
Copa Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to Panama from North Carolina according to our data. Copa Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.
How many flights depart from North Carolina to Panama on average per day?
The number of flights available between North Carolina and Panama is 1 per day as of August 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.
How many flights depart from North Carolina to Panama on average per week?
The number of flights available between North Carolina and Panama is 8 per week as of August 2026. The most frequent departure day is Mon, with 25% of weekly flights leaving on this day.
Cheap North Carolina to Panama flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama
Frequently asked questions about flying from North Carolina to Panama
When did momondo last update prices for flights from North Carolina to Panama?
Prices for flights from North Carolina to Panama refresh daily.
How many operators does momondo search for flights from North Carolina to Panama?
There are 4 operators available for flights from North Carolina to Panama as of August 2026.
How old do you have to be to fly from North Carolina to Panama?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from North Carolina to Panama?
momondo data reveals that the most frequently booked plane model on the route from North Carolina to Panama is Boeing 737 MAX 9, representing 55.79% of all bookings. The subsequent popular models are Boeing 737-800 at 27.37%, Embraer 190 at 6.32%, and Boeing 737 MAX 8 at 4.21%.
Best airlines flying from North Carolina to Panama
Compare and see reviews for airlines that fly from North Carolina to Panama with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $286 | Free Cancellation | Rating 7.8 8,503 reviews | |||
| PriceFrom $388 | Free Cancellation | Rating 7.6 1,557 reviews | |||
| PriceFrom $416 | Free Cancellation | Rating 7.1 11,919 reviews | |||
| PriceFrom $455 | Free Cancellation | Rating 7.4 10,115 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from North Carolina to Panama?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Panama for you.
Can I find flights from North Carolina to Panama with flexible booking policies on momondo?
Flights from North Carolina to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from North Carolina to Panama?
Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from North Carolina.
I’m not ready to book a flight from North Carolina to Panama right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of North Carolina to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.