What airlines fly to Panama?

Copa Airlines, American Airlines and Delta are the top three most popular airlines that fly to Panama from North Carolina according to our data. Copa Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How long is the flight from North Carolina to Panama?

Flight times from North Carolina to Panama vary, but if you’re flying out of Raleigh and flying into Panama City (one of the most popular routes), then the duration is 4h 24m on average. Another popular route from North Carolina to Panama is flying from Charlotte to Panama City, which will take roughly 6h 13m. Keep in mind that layovers or delays could extend your travel time.

How many flights depart from North Carolina to Panama on average per week?

The number of flights available between North Carolina and Panama is 7 per week as of March 2026. The most frequent departure day is Wed, with 29% of weekly flights leaving on this day.

What is the cheapest airline that flies from North Carolina to Panama?

United Airlines, American Airlines, and GOL are the most popular carriers operating from North Carolina to Panama

How many flights depart from North Carolina to Panama on average per day?

The number of flights available between North Carolina and Panama is 1 per day as of March 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.

When did momondo last update prices for flights from North Carolina to Panama?

Prices for flights from North Carolina to Panama refresh daily.

How many operators does momondo search for flights from North Carolina to Panama?

There are 4 operators available for flights from North Carolina to Panama as of March 2026.

How old do you have to be to fly from North Carolina to Panama?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$168 Cheap Flights from North Carolina to Panama in 2026

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Find the cheapest flights from North Carolina to Panama

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:09 am - 12:35 am

RDU

PTY

17h 26m

2 stops

5:30 am - 7:24 am

PTY

RDU

24h 54m

3 stops

$380Multiple Airlines

Sat, May 9 - Sat, May 16

9:03 am - 12:35 am

RDU

PTY

16h 32m

2 stops

3:10 pm - 7:24 am

PTY

RDU

15h 14m

2 stops

$392Multiple Airlines

Mon, Apr 27 - Wed, May 6

6:30 am - 12:35 am

CLT

PTY

19h 05m

2 stops

3:10 pm - 11:45 am

PTY

CLT

19h 35m

2 stops

$394Multiple Airlines

Thu, Apr 23 - Sun, Apr 26

5:05 am - 12:46 pm

CLT

PTY

8h 41m

1 stop

1:14 pm - 6:22 am

PTY

CLT

16h 08m

2 stops

$440American Airlines

Fri, May 15 - Fri, May 22

10:25 pm - 2:20 pm

CLT

PTY

16h 55m

1 stop

3:20 pm - 7:09 am

PTY

CLT

14h 49m

1 stop

$449American Airlines

Mon, Aug 10 - Tue, Aug 18

5:30 am - 1:13 pm

ORF

PTY

8h 43m

1 stop

2:28 pm - 12:06 am

PTY

ORF

8h 38m

1 stop

$467Delta

Wed, Aug 12 - Wed, Aug 26

7:59 pm - 6:37 pm

ORF

PTY

23h 38m

2 stops

10:00 am - 9:40 am

PTY

ORF

22h 40m

2 stops

$471United Airlines

Wed, Aug 12 - Wed, Aug 26

6:30 am - 6:37 pm

GSO

PTY

13h 07m

2 stops

10:00 am - 11:39 pm

PTY

GSO

12h 39m

2 stops

$491United Airlines

Thu, Sep 24 - Tue, Sep 29

6:00 am - 7:31 pm

GSO

PTY

14h 31m

1 stop

3:20 pm - 10:14 am

PTY

GSO

17h 54m

2 stops

$503Copa Airlines

Thu, Sep 24 - Tue, Sep 29

6:00 am - 12:50 pm

TRI

PTY

7h 50m

1 stop

2:15 pm - 10:40 pm

PTY

TRI

7h 25m

1 stop

$915Delta

Sat, May 9 - Sat, May 16

Delta flights from North Carolina to Panama

Our best Delta deals on North Carolina to Panama flight tickets

Delta

Aug 12

ORF5:30 amNorfolk

8h 43m

1 stop

PTY1:13 pmPanama City Tocumen Intl

Aug 26

PTY2:28 pmPanama City Tocumen Intl

8h 38m

1 stop

ORF12:06 amNorfolk

$467

Delta

Apr 13

CLT5:30 amCharlotte Douglas

8h 32m

1 stop

PTY1:02 pmPanama City Tocumen Intl

Apr 27

PTY2:27 pmPanama City Tocumen Intl

8h 26m

1 stop

CLT11:53 pmCharlotte Douglas

$499

Delta

Apr 13

CLT5:30 amCharlotte Douglas

8h 32m

1 stop

PTY1:02 pmPanama City Tocumen Intl

Apr 27

PTY2:27 pmPanama City Tocumen Intl

8h 26m

1 stop

CLT11:53 pmCharlotte Douglas

$519

United Airlines flights from North Carolina to Panama

Our best United Airlines deals on North Carolina to Panama flight tickets

United Airlines

Aug 12

ORF7:59 pmNorfolk

23h 38m

2 stops

PTY6:37 pmPanama City Tocumen Intl

Aug 26

PTY10:00 amPanama City Tocumen Intl

22h 40m

2 stops

ORF9:40 amNorfolk

$471

United Airlines

Sep 24

GSO6:30 amGreensboro/H. Point

13h 07m

2 stops

PTY6:37 pmPanama City Tocumen Intl

Sep 29

PTY10:00 amPanama City Tocumen Intl

12h 39m

2 stops

GSO11:39 pmGreensboro/H. Point

$491

United Airlines

Sep 5

ORF6:10 amNorfolk

9h 04m

1 stop

PTY2:14 pmPanama City Tocumen Intl

Sep 9

PTY9:45 amPanama City Tocumen Intl

12h 58m

2 stops

ORF11:43 pmNorfolk

$501

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 5/9

8:09 am-12:35 am

2 stops17h 26m

Panama City Tocumen Intl

Sat 5/16

5:30 am-7:24 am

3 stops24h 54m

$380

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 4/27

9:03 am-12:35 am

2 stops16h 32m

Panama City Tocumen Intl

Wed 5/6

3:10 pm-7:24 am

2 stops15h 14m

$392

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/23

6:30 am-12:35 am

2 stops19h 05m

Panama City Tocumen Intl

Sun 4/26

3:10 pm-11:45 am

2 stops19h 35m

$394

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 5/15

5:05 am-12:46 pm

1 stop8h 41m

Panama City Tocumen Intl

Fri 5/22

1:14 pm-6:22 am

2 stops16h 08m

$440

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 8/10

10:25 pm-2:20 pm

1 stop16h 55m

Panama City Tocumen Intl

Tue 8/18

3:20 pm-7:09 am

1 stop14h 49m

$449

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/12

5:30 am-1:13 pm

1 stop8h 43m

Panama City Tocumen Intl

Wed 8/26

2:28 pm-12:06 am

1 stop8h 38m

$467

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/12

7:59 pm-6:37 pm

2 stops23h 38m

Panama City Tocumen Intl

Wed 8/26

10:00 am-9:40 am

2 stops22h 40m

$471

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 9/24

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

Tue 9/29

10:00 am-11:39 pm

2 stops12h 39m

$491

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 9/24

6:00 am-7:31 pm

1 stop14h 31m

Panama City Tocumen Intl

Tue 9/29

3:20 pm-10:14 am

2 stops17h 54m

$503

Quickest round-trip

BlountvillePanama City

TRI - PTY

TRIPTY

Blountville Tri Cities TN/VA

Sat 5/9

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Sat 5/16

2:15 pm-10:40 pm

1 stop7h 25m

$915

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from North Carolina to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from North Carolina, with most prices found around $394. If you don’t want to visit Panama in October, then you should wait until September to fly from North Carolina, when ticket prices are also cheap, with an average price of $403.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from North Carolina. The lowest ticket price found for a Tuesday departure recently was $397. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from North Carolina to Panama for around $738.

What is the cheapest North Carolina to Panama flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best North Carolina - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $527 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from North Carolina for as low as $334 on momondo.

What cabin class options are available on North Carolina to Panama flights?

There are 3 cabin classes available to choose from on North Carolina to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Panama flights?

You could potentially save up to 59% on your flight if you consider stops on a North Carolina to Panama flight.

Cheap North Carolina to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama

Best Price Found	$159
Fastest flight time	4h 24m
Direct flights	Mon, Tue, Thu and Sat
Airports in Panama	21 airports

The best one-way flight to Panama from North Carolina in the past 72 hours is $159. The best round-trip flight deal from North Carolina to Panama found on momondo in the last 72 hours is $400.

The fastest flight from North Carolina to Panama takes 4h 24m

Direct flights go from North Carolina to Panama on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.

There are 21 airports in Panama. From North Carolina there are direct flights to Panama City Tocumen Intl (PTY).

Search flight deals

When did momondo last update prices for flights from North Carolina to Panama?
Prices for flights from North Carolina to Panama refresh daily.
How many operators does momondo search for flights from North Carolina to Panama?
There are 4 operators available for flights from North Carolina to Panama as of March 2026.
How old do you have to be to fly from North Carolina to Panama?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from North Carolina to Panama?
momondo data reveals that the most frequently booked plane model on the route from North Carolina to Panama is Boeing 737 MAX 9, representing 83.64% of all bookings. The subsequent popular models are Boeing 737-800 at 10.00%, Boeing 737 MAX 8 at 1.82%, and Embraer 190 at 1.82%.

Best airlines flying from North Carolina to Panama

Compare and see reviews for airlines that fly from North Carolina to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $255	Free Cancellation	Rating 7.1 11,518 reviews	Search American Airlines flights
Copa Airlines	PriceFrom $352	Free Cancellation	Rating 7.5 1,579 reviews	Search Copa Airlines flights
Delta	PriceFrom $367	Free Cancellation	Rating 7.9 8,350 reviews	Search Delta flights
United Airlines	PriceFrom $409	Free Cancellation	Rating 7.4 9,500 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Panama for you.

Can I find flights from North Carolina to Panama with flexible booking policies on momondo?

Flights from North Carolina to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from North Carolina to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from North Carolina.

I’m not ready to book a flight from North Carolina to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of North Carolina to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama trip

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Flights to Panama Cityfrom $284

Flights to Davidfrom $344

Flights to Bocas del Torofrom $742

Flights to Changuinola

Cheap flights from North Carolina to Panama from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from North Carolina to Panama

Our best Delta deals on North Carolina to Panama flight tickets

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See travel insights to Panama from

How to get the cheapest flight ticket from North Carolina to Panama

What is the cheapest month to fly to Panama?

What is the cheapest day to depart on your flight to Panama?

What is the cheapest North Carolina to Panama flight route?

How far in advance should I book a flight to Panama?

What cabin class options are available on North Carolina to Panama flights?

Can stopping save me money on North Carolina to Panama flights?

What is the cheapest airline that flies from North Carolina to Panama?

What airlines fly to Panama?

How many flights depart from North Carolina to Panama on average per day?

How many flights depart from North Carolina to Panama on average per week?

How long is the flight from North Carolina to Panama?

Cheap North Carolina to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama

Best Price Found

Fastest flight time

Direct flights

Airports in Panama

Best airlines flying from North Carolina to Panama

Compare and see reviews for airlines that fly from North Carolina to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

North Carolina flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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According to popular flight searches on momondo this year