Cheap flights from North Carolina to Panama from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from North Carolina to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:58 pm - 8:37 pm
CLT
-
PTY
7h 39m
1 stop
Multiple Airlines Logo
5:30 am - 4:05 pm
PTY
-
CLT
9h 35m
2 stops
$518Multiple Airlines
Sun, Sep 6 - Thu, Sep 10
Multiple Airlines Logo
1:58 pm - 8:37 pm
CLT
-
PTY
7h 39m
1 stop
Multiple Airlines Logo
3:10 pm - 4:05 pm
PTY
-
CLT
23h 55m
2 stops
$525Multiple Airlines
Mon, Sep 7 - Wed, Sep 9
Copa Airlines Logo
6:15 am - 8:35 pm
ORF
-
PTY
15h 20m
1 stop
Copa Airlines Logo
10:29 pm - 9:41 am
PTY
-
ORF
10h 12m
1 stop
$531Copa Airlines
Thu, Sep 3 - Wed, Sep 9
Copa Airlines Logo
6:00 am - 1:31 pm
CLT
-
PTY
7h 31m
1 stop
Copa Airlines Logo
6:46 pm - 10:04 am
PTY
-
CLT
15h 18m
1 stop
$533Copa Airlines
Thu, Nov 5 - Wed, Nov 11
United Airlines Logo
7:00 am - 7:31 pm
CLT
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 10:54 am
PTY
-
CLT
18h 24m
1 stop
$539United Airlines
Mon, Sep 28 - Thu, Oct 1
United Airlines Logo
10:49 am - 4:04 am
ORF
-
PTY
18h 15m
1 stop
United Airlines Logo
10:00 am - 3:13 pm
PTY
-
ORF
28h 13m
2 stops
$541United Airlines
Thu, Sep 3 - Wed, Sep 9
Delta Logo
5:30 pm - 12:55 pm
CLT
-
PTY
20h 25m
1 stop
Delta Logo
2:23 pm - 11:59 pm
PTY
-
CLT
8h 36m
1 stop
$546Delta
Sun, Sep 6 - Thu, Sep 10
Delta Logo
6:23 am - 12:55 pm
ORF
-
PTY
7h 32m
1 stop
Delta Logo
2:20 pm - 1:03 am
PTY
-
ORF
9h 43m
1 stop
$567Delta
Wed, Aug 12 - Wed, Aug 26
American Airlines Logo
6:00 am - 12:39 pm
TYS
-
PTY
7h 39m
1 stop
American Airlines Logo
1:39 pm - 11:51 pm
PTY
-
TYS
9h 12m
1 stop
$587American Airlines
Tue, Aug 18 - Fri, Sep 4
American Airlines Logo
6:00 am - 1:36 pm
ILM
-
PTY
7h 36m
1 stop
American Airlines Logo
2:43 pm - 11:44 pm
PTY
-
ILM
9h 01m
1 stop
$587American Airlines
Thu, Nov 12 - Tue, Nov 24

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Delta flights from North Carolina to Panama

Our best Delta deals on North Carolina to Panama flight tickets
Delta
Sep 6
CLT5:30 pmCharlotte Douglas
20h 25m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Sep 10
PTY2:23 pmPanama City Tocumen Intl
8h 36m
1 stop
CLT11:59 pmCharlotte Douglas
$546
Delta
Aug 12
ORF6:23 amNorfolk
7h 32m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Aug 26
PTY2:20 pmPanama City Tocumen Intl
9h 43m
1 stop
ORF1:03 amNorfolk
$567
Delta
Sep 6
CLT5:30 pmCharlotte Douglas
20h 25m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Sep 11
PTY2:23 pmPanama City Tocumen Intl
8h 36m
1 stop
CLT11:59 pmCharlotte Douglas
$576

Avianca flights from North Carolina to Panama

Our best Avianca deals on North Carolina to Panama flight tickets
Avianca
Jul 13
RDU9:40 amRaleigh-Durham
17h 15m
2 stops
PTY1:55 amPanama City Tocumen Intl
Jul 27
PTY5:30 amPanama City Tocumen Intl
14h 37m
2 stops
RDU9:07 pmRaleigh-Durham
$628
Avianca
Jun 30
RDU4:00 pmRaleigh-Durham
34h 55m
2 stops
PTY1:55 amPanama City Tocumen Intl
Jul 6
PTY5:30 amPanama City Tocumen Intl
32h 55m
2 stops
RDU3:25 pmRaleigh-Durham
$700
Avianca
Jul 5
RDU9:40 amRaleigh-Durham
17h 15m
2 stops
PTY1:55 amPanama City Tocumen Intl
Jul 13
PTY5:30 amPanama City Tocumen Intl
14h 37m
2 stops
RDU9:07 pmRaleigh-Durham
$714

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 9/6

1:58 pm-8:37 pm

1 stop7h 39m

Panama City Tocumen Intl

Thu 9/10

5:30 am-4:05 pm

2 stops9h 35m

$518

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 9/7

1:58 pm-8:37 pm

1 stop7h 39m

Panama City Tocumen Intl

Wed 9/9

3:10 pm-4:05 pm

2 stops23h 55m

$525

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 9/3

6:15 am-8:35 pm

1 stop15h 20m

Panama City Tocumen Intl

Wed 9/9

10:29 pm-9:41 am

1 stop10h 12m

$531

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/5

6:00 am-1:31 pm

1 stop7h 31m

Panama City Tocumen Intl

Wed 11/11

6:46 pm-10:04 am

1 stop15h 18m

$533

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 9/28

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:54 am

1 stop18h 24m

$539

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 9/3

10:49 am-4:04 am

1 stop18h 15m

Panama City Tocumen Intl

Wed 9/9

10:00 am-3:13 pm

2 stops28h 13m

$541

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 9/6

5:30 pm-12:55 pm

1 stop20h 25m

Panama City Tocumen Intl

Thu 9/10

2:23 pm-11:59 pm

1 stop8h 36m

$546

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/12

6:23 am-12:55 pm

1 stop7h 32m

Panama City Tocumen Intl

Wed 8/26

2:20 pm-1:03 am

1 stop9h 43m

$567

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 8/18

6:00 am-12:39 pm

1 stop7h 39m

Panama City Tocumen Intl

Fri 9/4

1:39 pm-11:51 pm

1 stop9h 12m

$587
Quickest round-trip

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Thu 11/12

6:00 am-1:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Tue 11/24

2:43 pm-11:44 pm

1 stop9h 01m

$587

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from North Carolina to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from North Carolina, with most prices found around $184. If you don’t want to visit Panama in August, then you should wait until December to fly from North Carolina, when ticket prices are also cheap, with an average price of $221.

What is the cheapest North Carolina to Panama flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best North Carolina - Panama flight prices

How far in advance should I book a flight from North Carolina to Panama?

You are more likely to see cheaper flights to Panama from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $581 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from North Carolina for as low as $494 on momondo.

What cabin class options are available on North Carolina to Panama flights?

There are 3 cabin classes available to choose from on North Carolina to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Panama flights?

You could potentially save up to 68% on your flight if you consider stops on a North Carolina to Panama flight.

Cheap North Carolina to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama

Best Price Found

$319

Fastest flight time

4h 24m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from North Carolina in the past 72 hours is $319. The best round-trip flight deal from North Carolina to Panama found on momondo in the last 72 hours is $402.
The fastest flight from North Carolina to Panama takes 4h 24m
Direct flights go from North Carolina to Panama on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From North Carolina there are direct flights to Panama City Tocumen Intl (PTY).

Frequently asked questions about flying from North Carolina to Panama

  • When did momondo last update prices for flights from North Carolina to Panama?

    Prices for flights from North Carolina to Panama refresh daily.

  • How many operators does momondo search for flights from North Carolina to Panama?

  • How old do you have to be to fly from North Carolina to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from North Carolina to Panama?

Best airlines flying from North Carolina to Panama

Compare and see reviews for airlines that fly from North Carolina to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $184Free CancellationRating
7.8
8,449 reviews
Search Delta flights
Copa AirlinesPriceFrom $352Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $416Free CancellationRating
7.1
11,770 reviews
Search American Airlines flights
United AirlinesPriceFrom $455Free CancellationRating
7.4
9,894 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Panama for you.

Can I find flights from North Carolina to Panama with flexible booking policies on momondo?

Flights from North Carolina to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from North Carolina to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from North Carolina.

I’m not ready to book a flight from North Carolina to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of North Carolina to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Wed 7/29
Wed 8/5

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