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Cheap flights from Myrtle Beach to Guayaquil from $243

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Guayaquil departing on 4/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:55 pm - 11:04 pm
MYR
-
GYE
30h 09m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$351Multiple Airlines
ter, abr 21 - sex, abr 24
Spirit Airlines Logo
5:55 pm - 11:04 pm
MYR
-
GYE
30h 09m
1 stop
Spirit Airlines Logo
11:59 pm - 11:29 pm
GYE
-
MYR
22h 30m
1 stop
$352Spirit Airlines
ter, abr 21 - sex, abr 24
Multiple Airlines Logo
11:28 am - 11:04 pm
MYR
-
GYE
12h 36m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$356Multiple Airlines
qua, abr 22 - sex, abr 24
Multiple Airlines Logo
11:52 am - 11:04 pm
MYR
-
GYE
12h 12m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$387Multiple Airlines
qui, abr 23 - dom, abr 26
Spirit Airlines Logo
11:52 am - 11:04 pm
MYR
-
GYE
12h 12m
1 stop
Spirit Airlines Logo
11:59 pm - 11:29 pm
GYE
-
MYR
22h 30m
1 stop
$393Spirit Airlines
qui, abr 23 - dom, abr 26
Multiple Airlines Logo
11:52 am - 11:04 pm
MYR
-
GYE
12h 12m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$400Multiple Airlines
qui, abr 23 - dom, abr 26
Spirit Airlines Logo
11:52 am - 11:04 pm
MYR
-
GYE
12h 12m
1 stop
Spirit Airlines Logo
11:59 pm - 11:29 pm
GYE
-
MYR
22h 30m
1 stop
$406Spirit Airlines
qui, abr 23 - dom, abr 26
Multiple Airlines Logo
11:52 am - 8:55 am
MYR
-
GYE
22h 03m
2 stops
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$409Multiple Airlines
qui, abr 23 - dom, abr 26
Multiple Airlines Logo
8:31 pm - 11:04 pm
MYR
-
GYE
27h 33m
2 stops
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$417Multiple Airlines
ter, abr 21 - sex, abr 24
Multiple Airlines Logo
8:31 pm - 11:04 pm
MYR
-
GYE
27h 33m
3 stops
Multiple Airlines Logo
3:45 pm - 11:29 pm
GYE
-
MYR
30h 44m
2 stops
$478Multiple Airlines
ter, abr 21 - sex, abr 24

Spirit Airlines flights from Myrtle Beach to Guayaquil

Our best Spirit Airlines deals on Myrtle Beach to Guayaquil flight tickets
Spirit Airlines
Apr 21
MYR5:55 pmMyrtle Beach Intl
30h 09m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 24
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
22h 30m
1 stop
MYR11:29 pmMyrtle Beach Intl
$352
Spirit Airlines
Apr 23
MYR11:52 amMyrtle Beach Intl
12h 12m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 26
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
22h 30m
1 stop
MYR11:29 pmMyrtle Beach Intl
$393
Spirit Airlines
Apr 23
MYR11:52 amMyrtle Beach Intl
12h 12m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 26
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
22h 30m
1 stop
MYR11:29 pmMyrtle Beach Intl
$406

LATAM Airlines flights from Myrtle Beach to Guayaquil

Our best LATAM Airlines deals on Myrtle Beach to Guayaquil flight tickets
LATAM Airlines
Apr 20
MYR10:26 amMyrtle Beach Intl
21h 49m
2 stops
GYE7:15 amGuayaquil Jose Joaquin de Olmedo
Apr 23
GYE9:05 amGuayaquil Jose Joaquin de Olmedo
14h 09m
2 stops
MYR12:14 amMyrtle Beach Intl
$995
LATAM Airlines
Apr 20
MYR6:00 amMyrtle Beach Intl
26h 54m
2 stops
GYE7:54 amGuayaquil Jose Joaquin de Olmedo
Apr 23
GYE2:58 pmGuayaquil Jose Joaquin de Olmedo
20h 59m
2 stops
MYR12:57 pmMyrtle Beach Intl
$996
LATAM Airlines
Apr 20
MYR6:00 amMyrtle Beach Intl
26h 54m
2 stops
GYE7:54 amGuayaquil Jose Joaquin de Olmedo
Apr 23
GYE2:58 pmGuayaquil Jose Joaquin de Olmedo
26h 08m
2 stops
MYR6:06 pmMyrtle Beach Intl
$998

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated abril 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

ter 4/21

5:55 pm-11:04 pm

1 stop30h 09m

Guayaquil Jose Joaquin de Olmedo

sex 4/24

6:50 pm-11:29 pm

2 stops27h 39m

$351

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

ter 4/21

5:55 pm-11:04 pm

1 stop30h 09m

Guayaquil Jose Joaquin de Olmedo

sex 4/24

11:59 pm-11:29 pm

1 stop22h 30m

$352

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qua 4/22

11:28 am-11:04 pm

1 stop12h 36m

Guayaquil Jose Joaquin de Olmedo

sex 4/24

6:50 pm-11:29 pm

2 stops27h 39m

$356

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qui 4/23

11:52 am-11:04 pm

1 stop12h 12m

Guayaquil Jose Joaquin de Olmedo

dom 4/26

6:50 pm-11:29 pm

2 stops27h 39m

$387
Quickest round-trip

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qui 4/23

11:52 am-11:04 pm

1 stop12h 12m

Guayaquil Jose Joaquin de Olmedo

dom 4/26

11:59 pm-11:29 pm

1 stop22h 30m

$393

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qui 4/23

11:52 am-11:04 pm

1 stop12h 12m

Guayaquil Jose Joaquin de Olmedo

dom 4/26

6:50 pm-11:29 pm

2 stops27h 39m

$400

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qui 4/23

11:52 am-11:04 pm

1 stop12h 12m

Guayaquil Jose Joaquin de Olmedo

dom 4/26

11:59 pm-11:29 pm

1 stop22h 30m

$406

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

qui 4/23

11:52 am-8:55 am

2 stops22h 03m

Guayaquil Jose Joaquin de Olmedo

dom 4/26

6:50 pm-11:29 pm

2 stops27h 39m

$409

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

ter 4/21

8:31 pm-11:04 pm

2 stops27h 33m

Guayaquil Jose Joaquin de Olmedo

sex 4/24

6:50 pm-11:29 pm

2 stops27h 39m

$417

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

ter 4/21

8:31 pm-11:04 pm

3 stops27h 33m

Guayaquil Jose Joaquin de Olmedo

sex 4/24

3:45 pm-11:29 pm

2 stops30h 44m

$478

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to Guayaquil flights?

You could potentially save up to 26% on your flight if you consider stops on a Myrtle Beach to Guayaquil flight.

When to book flights from Myrtle Beach to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Guayaquil (MYR to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Guayaquil

Fastest flight time

27h 59m

Direct flights

None
The fastest flight from Myrtle Beach to Guayaquil takes 27h 59m
There are no direct flights from Myrtle Beach to Guayaquil. There are no popular flight routes from Myrtle Beach to Guayaquil.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Guayaquil

  • How far is Myrtle Beach Intl to Guayaquil Jose Joaquin de Olmedo by plane?

    The distance between Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo is about 2478.4 mi. 27h 59m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Myrtle Beach Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from Myrtle Beach.

Can I find flights from Myrtle Beach to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Guayaquil?

momondo helps you find the best flight between Myrtle Beach and Guayaquil by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Myrtle Beach to Guayaquil right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Guayaquil flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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