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Cheap flights from Missouri to Santiago from $301

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santiago departing on 1/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
1:00 pm - 7:00 amSTL-SCL
16h 00m2 stops
LATAM Airlines Logo
11:25 pm - 7:14 pmSCL-STL
21h 49m2 stops
$735LATAM Airlines
Find Deal
mié., mar. 11 - lun., mar. 23
LATAM Airlines Logo
10:00 am - 5:35 amSTL-SCL
17h 35m2 stops
LATAM Airlines Logo
11:25 pm - 7:14 pmSCL-STL
21h 49m2 stops
$738LATAM Airlines
Find Deal
mié., mar. 11 - lun., mar. 23
United Airlines Logo
6:00 am - 7:50 amSTL-SCL
23h 50m1 stop
United Airlines Logo
9:45 pm - 9:24 amSCL-STL
13h 39m1 stop
$756United Airlines
Find Deal
mié., mar. 11 - lun., mar. 23
United Airlines Logo
6:00 am - 7:50 amSTL-SCL
23h 50m1 stop
United Airlines Logo
9:45 pm - 9:24 amSCL-STL
13h 39m1 stop
$758United Airlines
Find Deal
mié., mar. 11 - lun., mar. 23
Delta Logo
3:15 pm - 7:40 amSTL-SCL
13h 25m1 stop
Delta Logo
9:30 pm - 8:24 amSCL-STL
13h 54m1 stop
$764Delta
Find Deal
jue., nov. 27 - lun., dic. 8
Delta Logo
6:00 am - 7:00 amSTL-SCL
22h 00m2 stops
Delta Logo
10:35 am - 11:42 pmSCL-STL
16h 07m2 stops
$769Delta
Find Deal
jue., nov. 27 - lun., dic. 8
American Airlines Logo
11:42 am - 7:50 amMCI-SCL
17h 08m1 stop
American Airlines Logo
10:30 pm - 11:05 amSCL-MCI
15h 35m1 stop
$814American Airlines
Find Deal
mié., ene. 7 - mié., ene. 14
American Airlines Logo
6:44 am - 7:45 amMCI-SCL
22h 01m1 stop
American Airlines Logo
10:30 pm - 11:12 pmSCL-MCI
27h 42m1 stop
$817American Airlines
Find Deal
jue., dic. 11 - mar., ene. 13
Multiple Airlines Logo
2:47 pm - 1:09 amSTL-SCL
31h 22m3 stops
Multiple Airlines Logo
3:45 pm - 1:52 pmSCL-STL
25h 07m3 stops
$971Multiple Airlines
Find Deal
dom., dic. 7 - sáb., dic. 13
Multiple Airlines Logo
6:00 am - 12:30 amMCI-SCL
39h 30m3 stops
Multiple Airlines Logo
1:35 am - 6:36 pmSCL-MCI
20h 01m2 stops
$1,032Multiple Airlines
Find Deal
mar., nov. 25 - dom., nov. 30

American Airlines flights from Missouri to Santiago

Our best American Airlines deals on Missouri to Santiago flight tickets
American Airlines
Jan 7
MCI11:42 amKansas City
17h 08m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Jan 14
SCL10:30 pmSantiago Arturo Merino Benitez
15h 35m
1 stop
MCI11:05 amKansas City
$814
Find similar
American Airlines
Dec 11
MCI6:44 amKansas City
22h 01m
1 stop
SCL7:45 amSantiago Arturo Merino Benitez
Jan 13
SCL10:30 pmSantiago Arturo Merino Benitez
27h 42m
1 stop
MCI11:12 pmKansas City
$817
Find similar
American Airlines
Dec 11
MCI1:40 pmKansas City
16h 15m
2 stops
SCL8:55 amSantiago Arturo Merino Benitez
Jan 13
SCL10:30 pmSantiago Arturo Merino Benitez
27h 42m
1 stop
MCI11:12 pmKansas City
$821
Find similar

Delta flights from Missouri to Santiago

Our best Delta deals on Missouri to Santiago flight tickets
Delta
Nov 27
STL3:15 pmLambert-St Louis
13h 25m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 8
SCL9:30 pmSantiago Arturo Merino Benitez
13h 54m
1 stop
STL8:24 amLambert-St Louis
$764
Find similar
Delta
Nov 27
STL6:00 amLambert-St Louis
22h 00m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Dec 8
SCL10:35 amSantiago Arturo Merino Benitez
16h 07m
2 stops
STL11:42 pmLambert-St Louis
$769
Find similar
Delta
Nov 23
MCI6:38 pmKansas City
34h 02m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 3
SCL6:30 pmSantiago Arturo Merino Benitez
17h 59m
2 stops
MCI9:29 amKansas City
$773
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Missouri to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

mié. 3/11

1:00 pm-7:00 am

2 stops16h 00m

Santiago Arturo Merino Benitez

lun. 3/23

11:25 pm-7:14 pm

2 stops21h 49m

$735

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

mié. 3/11

10:00 am-5:35 am

2 stops17h 35m

Santiago Arturo Merino Benitez

lun. 3/23

11:25 pm-7:14 pm

2 stops21h 49m

$738

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

mié. 3/11

6:00 am-7:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

lun. 3/23

9:45 pm-9:24 am

1 stop13h 39m

$756

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

mié. 3/11

6:00 am-7:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

lun. 3/23

9:45 pm-9:24 am

1 stop13h 39m

$758

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

jue. 11/27

3:15 pm-7:40 am

1 stop13h 25m

Santiago Arturo Merino Benitez

lun. 12/8

9:30 pm-8:24 am

1 stop13h 54m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

jue. 11/27

6:00 am-7:00 am

2 stops22h 00m

Santiago Arturo Merino Benitez

lun. 12/8

10:35 am-11:42 pm

2 stops16h 07m

$769

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

mié. 1/7

11:42 am-7:50 am

1 stop17h 08m

Santiago Arturo Merino Benitez

mié. 1/14

10:30 pm-11:05 am

1 stop15h 35m

$814

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

jue. 12/11

6:44 am-7:45 am

1 stop22h 01m

Santiago Arturo Merino Benitez

mar. 1/13

10:30 pm-11:12 pm

1 stop27h 42m

$817

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

dom. 12/7

2:47 pm-1:09 am

3 stops31h 22m

Santiago Arturo Merino Benitez

sáb. 12/13

3:45 pm-1:52 pm

3 stops25h 07m

$971

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

mar. 11/25

6:00 am-12:30 am

3 stops39h 30m

Santiago Arturo Merino Benitez

dom. 11/30

1:35 am-6:36 pm

2 stops20h 01m

$1,032

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, July is the cheapest month to fly from Missouri to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $878. If you don’t want to visit Santiago in July, then you should wait until March to fly from Missouri, when ticket prices are also cheap, with an average price of $883.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Missouri to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $995 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Missouri for as low as $740 on momondo.

Cheap Missouri to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santiago

Direct flights

None
There are no direct flights from Missouri to Santiago. There are no popular flight routes from Missouri to Santiago.
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  • When did momondo last update prices for flights from Missouri to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Missouri to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Missouri to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santiago

Compare and see reviews for airlines that fly from Missouri to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $689Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $764Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $773Free CancellationRating
7.5
1,872 reviews
Search LATAM Airlines flights
DeltaPriceFrom $802Free CancellationRating
7.9
8,001 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Missouri.

Can I find flights from Missouri to Santiago with flexible booking policies on momondo?

Flights from Missouri to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Missouri to Santiago.

I’m not ready to book a flight from Missouri to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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