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Cheap flights from Missouri to Santiago from $400

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santiago departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Missouri to Santiago

Cheap round-trip flights

Logo
6:00 am - 1:25 pmMCI-SCL
30h 25m3 stops
Logo
2:30 pm - 10:53 pmSCL-MCI
33h 23m3 stops
$642
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Fri, Aug 15 - Tue, Aug 19
Logo
5:40 pm - 4:15 amSTL-SCL
33h 35m2 stops
Logo
9:45 am - 11:47 pmSCL-STL
15h 02m1 stop
$724
Find Deal
Mon, Aug 11 - Thu, Aug 14
United Airlines Logo
8:20 am - 8:50 amSTL-SCL
21h 30m1 stop
United Airlines Logo
10:45 pm - 10:04 amSCL-STL
14h 19m1 stop
$784United Airlines
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Thu, Nov 27 - Wed, Dec 10
United Airlines Logo
10:00 am - 8:50 amSTL-SCL
19h 50m2 stops
United Airlines Logo
10:45 pm - 12:15 pmSCL-STL
16h 30m2 stops
$788United Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 11
American Airlines Logo
10:53 am - 8:00 amMCI-SCL
19h 07m2 stops
American Airlines Logo
9:55 pm - 2:58 pmSCL-MCI
19h 03m2 stops
$788American Airlines
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Mon, Oct 6 - Wed, Oct 8
American Airlines Logo
5:00 am - 8:00 amMCI-SCL
25h 00m1 stop
American Airlines Logo
9:55 pm - 3:59 pmSCL-MCI
20h 04m2 stops
$799American Airlines
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Mon, Oct 6 - Wed, Oct 8
Delta Logo
6:00 am - 5:40 amSTL-SCL
20h 40m2 stops
Delta Logo
6:30 pm - 10:46 amSCL-STL
19h 16m2 stops
$804Delta
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Thu, Nov 27 - Mon, Dec 8
LATAM Airlines Logo
9:00 am - 9:35 pmSTL-SCL
33h 35m3 stops
LATAM Airlines Logo
9:30 pm - 6:02 pmSCL-STL
23h 32m1 stop
$808LATAM Airlines
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Sun, Nov 30 - Thu, Dec 11
Delta Logo
7:05 pm - 7:00 amSTL-SCL
32h 55m1 stop
Delta Logo
6:30 pm - 10:46 amSCL-STL
19h 16m2 stops
$812Delta
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Sun, Nov 30 - Mon, Dec 8
LATAM Airlines Logo
8:30 am - 6:25 amSTL-SCL
18h 55m2 stops
LATAM Airlines Logo
7:15 am - 11:39 pmSCL-STL
19h 24m3 stops
$878LATAM Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8

LATAM Airlines flights from Missouri to Santiago

Our best LATAM Airlines deals on Missouri to Santiago flight tickets
LATAM Airlines
Nov 30
STL9:00 amLambert-St Louis
33h 35m
3 stops
SCL9:35 pmSantiago Arturo Merino Benitez
Dec 11
SCL9:30 pmSantiago Arturo Merino Benitez
23h 32m
1 stop
STL6:02 pmLambert-St Louis
$808
Find similar
LATAM Airlines
Nov 27
STL8:30 amLambert-St Louis
18h 55m
2 stops
SCL6:25 amSantiago Arturo Merino Benitez
Dec 8
SCL7:15 amSantiago Arturo Merino Benitez
19h 24m
3 stops
STL11:39 pmLambert-St Louis
$878
Find similar
LATAM Airlines
Nov 28
STL3:15 pmLambert-St Louis
12h 45m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Dec 6
SCL11:15 pmSantiago Arturo Merino Benitez
14h 31m
1 stop
STL10:46 amLambert-St Louis
$884
Find similar

Delta flights from Missouri to Santiago

Our best Delta deals on Missouri to Santiago flight tickets
Delta
Nov 27
STL6:00 amLambert-St Louis
20h 40m
2 stops
SCL5:40 amSantiago Arturo Merino Benitez
Dec 8
SCL6:30 pmSantiago Arturo Merino Benitez
19h 16m
2 stops
STL10:46 amLambert-St Louis
$804
Find similar
Delta
Nov 30
STL7:05 pmLambert-St Louis
32h 55m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Dec 8
SCL6:30 pmSantiago Arturo Merino Benitez
19h 16m
2 stops
STL10:46 amLambert-St Louis
$812
Find similar
Delta
Nov 28
STL6:00 amLambert-St Louis
21h 35m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Dec 9
SCL8:50 amSantiago Arturo Merino Benitez
18h 47m
2 stops
STL12:37 amLambert-St Louis
$844
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Missouri to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Fri 8/15

6:00 am-1:25 pm

3 stops30h 25m

Santiago Arturo Merino Benitez

Tue 8/19

2:30 pm-10:53 pm

3 stops33h 23m

$642

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 8/11

5:40 pm-4:15 am

2 stops33h 35m

Santiago Arturo Merino Benitez

Thu 8/14

9:45 am-11:47 pm

1 stop15h 02m

$724

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

8:20 am-8:50 am

1 stop21h 30m

Santiago Arturo Merino Benitez

Wed 12/10

10:45 pm-10:04 am

1 stop14h 19m

$784

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

10:00 am-8:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Thu 12/11

10:45 pm-12:15 pm

2 stops16h 30m

$788

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Mon 10/6

10:53 am-8:00 am

2 stops19h 07m

Santiago Arturo Merino Benitez

Wed 10/8

9:55 pm-2:58 pm

2 stops19h 03m

$788

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Mon 10/6

5:00 am-8:00 am

1 stop25h 00m

Santiago Arturo Merino Benitez

Wed 10/8

9:55 pm-3:59 pm

2 stops20h 04m

$799

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

6:00 am-5:40 am

2 stops20h 40m

Santiago Arturo Merino Benitez

Mon 12/8

6:30 pm-10:46 am

2 stops19h 16m

$804

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sun 11/30

9:00 am-9:35 pm

3 stops33h 35m

Santiago Arturo Merino Benitez

Thu 12/11

9:30 pm-6:02 pm

1 stop23h 32m

$808

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sun 11/30

7:05 pm-7:00 am

1 stop32h 55m

Santiago Arturo Merino Benitez

Mon 12/8

6:30 pm-10:46 am

2 stops19h 16m

$812

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

8:30 am-6:25 am

2 stops18h 55m

Santiago Arturo Merino Benitez

Mon 12/8

7:15 am-11:39 pm

3 stops19h 24m

$878

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Missouri to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Missouri to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $772. If you don’t want to visit Santiago in October, then you should wait until July to fly from Missouri, when ticket prices are also cheap, with an average price of $878.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Missouri to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $978 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Missouri for as low as $902 on momondo.

Cheap Missouri to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santiago

Best Price Found

$400

Fastest flight time

11h 45m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Missouri in the past 72 hours is $400. The best round-trip flight deal from Missouri to Santiago found on momondo in the last 72 hours is $642.
The fastest flight from Missouri to Santiago takes 11h 45m
There are no direct flights from Missouri to Santiago. Popular non-direct routes for this connection are Lambert-St Louis Airport - Santiago Arturo Merino Benitez Airport, Joplin Airport - Santiago Arturo Merino Benitez Airport and Kansas City Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • When did momondo last update prices for flights from Missouri to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Missouri to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Missouri to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santiago

Compare and see reviews for airlines that fly from Missouri to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $742Free CancellationRating
8.0
7,981 reviews
Search Delta flights
LATAM AirlinesPriceFrom $762Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $807Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $883Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Missouri.

Can I find flights from Missouri to Santiago with flexible booking policies on momondo?

Flights from Missouri to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Missouri to Santiago.

I’m not ready to book a flight from Missouri to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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