How long does it take to fly to Santiago?

On average, it takes 12h to fly from Missouri to Santiago if you fly out of St. Louis (the most popular airport in Missouri) and into Santiago (the most popular airport in Santiago). If you’re flying out of Springfield and into Santiago, then the flight time is around 15h 18m.

What is the cheapest airline that flies from Missouri to Santiago Arturo Merino Benitez?

American Airlines is the most popular carrier operating from Missouri to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from Missouri according to our data. Delta is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Missouri to Santiago Arturo Merino Benitez Airport?

Prices for flights from Missouri to Santiago Arturo Merino Benitez Airport refresh daily.

How many operators does momondo search for flights from Missouri to Santiago Arturo Merino Benitez Airport?

There are 3 operators available for flights from Missouri to Santiago Arturo Merino Benitez Airport as of June 2026.

How old do you have to be to fly from Missouri to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$295 Cheap Flights from Missouri to Santiago in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:38 am - 2:05 pm

SGF

SCL

25h 27m

2 stops

8:40 pm - 6:17 pm

SCL

SGF

22h 37m

1 stop

$885Delta

Thu, Aug 13 - Thu, Aug 20

11:38 am - 6:00 am

SGF

SCL

17h 22m

2 stops

10:55 pm - 10:21 pm

SCL

SGF

24h 26m

2 stops

$890Delta

Thu, Aug 13 - Thu, Aug 20

6:06 am - 6:55 am

SGF

SCL

23h 49m

2 stops

8:30 am - 10:53 am

SCL

SGF

27h 23m

3 stops

$894LATAM Airlines

Thu, Aug 13 - Thu, Aug 20

11:38 am - 5:25 pm

SGF

SCL

28h 47m

2 stops

4:30 pm - 10:21 pm

SCL

SGF

30h 51m

2 stops

$915LATAM Airlines

Sat, Aug 22 - Wed, Aug 26

11:38 am - 7:15 am

SGF

SCL

18h 37m

1 stop

11:00 pm - 10:21 pm

SCL

SGF

24h 21m

2 stops

$920LATAM Airlines

Sat, Aug 22 - Wed, Aug 26

11:35 am - 6:25 am

STL

SCL

17h 50m

1 stop

9:50 pm - 10:45 am

SCL

STL

14h 55m

1 stop

$947American Airlines

Tue, Sep 1 - Sun, Sep 6

3:20 pm - 9:15 pm

SGF

SCL

28h 55m

3 stops

8:30 am - 6:17 pm

SCL

SGF

34h 47m

3 stops

$951LATAM Airlines

Thu, Aug 13 - Thu, Aug 20

12:45 pm - 6:25 am

STL

SCL

16h 40m

2 stops

9:50 pm - 10:45 am

SCL

STL

14h 55m

1 stop

$952American Airlines

Tue, Sep 1 - Sun, Sep 6

11:00 am - 7:50 am

STL

SCL

18h 50m

1 stop

10:45 pm - 6:25 pm

SCL

STL

22h 40m

1 stop

$977United Airlines

Wed, Oct 28 - Sun, Nov 1

11:00 am - 7:50 am

STL

SCL

18h 50m

1 stop

10:45 pm - 11:09 pm

SCL

STL

27h 24m

2 stops

$982United Airlines

Wed, Oct 28 - Sun, Nov 1

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Delta flights from Missouri to Santiago

Our best Delta deals on Missouri to Santiago flight tickets

Delta

Aug 13

SGF11:38 amSpringfield-Branson

25h 27m

2 stops

SCL2:05 pmSantiago Arturo Merino Benitez

Aug 20

SCL8:40 pmSantiago Arturo Merino Benitez

22h 37m

1 stop

SGF6:17 pmSpringfield-Branson

$885

Delta

Aug 13

SGF11:38 amSpringfield-Branson

17h 22m

2 stops

SCL6:00 amSantiago Arturo Merino Benitez

Aug 20

SCL10:55 pmSantiago Arturo Merino Benitez

24h 26m

2 stops

SGF10:21 pmSpringfield-Branson

$890

Delta

Jul 22

STL7:08 amLambert-St Louis

23h 07m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Sep 2

SCL8:40 pmSantiago Arturo Merino Benitez

16h 06m

1 stop

STL11:46 amLambert-St Louis

$1,150

LATAM Airlines flights from Missouri to Santiago

Our best LATAM Airlines deals on Missouri to Santiago flight tickets

LATAM Airlines

Aug 13

SGF6:06 amSpringfield-Branson

23h 49m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Aug 20

SCL8:30 amSantiago Arturo Merino Benitez

27h 23m

3 stops

SGF10:53 amSpringfield-Branson

$894

LATAM Airlines

Aug 22

SGF4:00 pmSpringfield-Branson

14h 15m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Aug 26

SCL11:05 pmSantiago Arturo Merino Benitez

24h 16m

2 stops

SGF10:21 pmSpringfield-Branson

$915

LATAM Airlines

Aug 22

SGF11:38 amSpringfield-Branson

24h 47m

3 stops

SCL1:25 pmSantiago Arturo Merino Benitez

Aug 26

SCL11:00 pmSantiago Arturo Merino Benitez

24h 21m

2 stops

SGF10:21 pmSpringfield-Branson

$920

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 8/13

11:38 am-2:05 pm

2 stops25h 27m

Santiago Arturo Merino Benitez

Thu 8/20

8:40 pm-6:17 pm

1 stop22h 37m

$885

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 8/13

11:38 am-6:00 am

2 stops17h 22m

Santiago Arturo Merino Benitez

Thu 8/20

10:55 pm-10:21 pm

2 stops24h 26m

$890

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 8/13

6:06 am-6:55 am

2 stops23h 49m

Santiago Arturo Merino Benitez

Thu 8/20

8:30 am-10:53 am

3 stops27h 23m

$894

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Sat 8/22

11:38 am-5:25 pm

2 stops28h 47m

Santiago Arturo Merino Benitez

Wed 8/26

4:30 pm-10:21 pm

2 stops30h 51m

$915

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Sat 8/22

11:38 am-7:15 am

1 stop18h 37m

Santiago Arturo Merino Benitez

Wed 8/26

11:00 pm-10:21 pm

2 stops24h 21m

$920

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 9/1

11:35 am-6:25 am

1 stop17h 50m

Santiago Arturo Merino Benitez

Sun 9/6

9:50 pm-10:45 am

1 stop14h 55m

$947

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 8/13

3:20 pm-9:15 pm

3 stops28h 55m

Santiago Arturo Merino Benitez

Thu 8/20

8:30 am-6:17 pm

3 stops34h 47m

$951

Quickest round-trip

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 9/1

12:45 pm-6:25 am

2 stops16h 40m

Santiago Arturo Merino Benitez

Sun 9/6

9:50 pm-10:45 am

1 stop14h 55m

$952

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 10/28

11:00 am-7:50 am

1 stop18h 50m

Santiago Arturo Merino Benitez

Sun 11/1

10:45 pm-6:25 pm

1 stop22h 40m

$977

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 10/28

11:00 am-7:50 am

1 stop18h 50m

Santiago Arturo Merino Benitez

Sun 11/1

10:45 pm-11:09 pm

2 stops27h 24m

$982

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from Missouri to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $472. If you don’t want to visit Santiago in March, then you should wait until September to fly from Missouri, when ticket prices are also cheap, with an average price of $623.

Can stopping save me money on Missouri to Santiago flights?

You could potentially save up to 13% on your flight if you consider stops on a Missouri to Santiago flight.

Cheap Missouri to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santiago

Fastest flight time	12h 00m
Direct flights	None

The fastest flight from Missouri to Santiago takes 12h 00m

There are no direct flights from Missouri to Santiago. There are no popular flight routes from Missouri to Santiago.

Search flight deals

Frequently asked questions about flying from Missouri to Santiago

When did momondo last update prices for flights from Missouri to Santiago Arturo Merino Benitez Airport?
Prices for flights from Missouri to Santiago Arturo Merino Benitez Airport refresh daily.
How many operators does momondo search for flights from Missouri to Santiago Arturo Merino Benitez Airport?
There are 3 operators available for flights from Missouri to Santiago Arturo Merino Benitez Airport as of June 2026.
How old do you have to be to fly from Missouri to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santiago

Compare and see reviews for airlines that fly from Missouri to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $611	Free Cancellation	Rating 7.8 8,450 reviews	Search Delta flights
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.1 11,766 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $792	Free Cancellation	Rating 7.4 1,941 reviews	Search LATAM Airlines flights

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San Fernando

Pichilemu

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Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Missouri.

Can I find flights from Missouri to Santiago with flexible booking policies on momondo?

Flights from Missouri to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Missouri to Santiago.

I’m not ready to book a flight from Missouri to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.