Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Missouri to Santiago from $379

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santiago departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Missouri to Santiago

Cheap round-trip flights

Delta Logo
11:04 am - 6:35 amSTL-SCL
16h 31m2 stops
Delta Logo
6:30 pm - 1:00 pmSCL-STL
21h 30m2 stops
$764Delta
Find Deal
Thu, Nov 27 - Mon, Dec 8
Delta Logo
10:35 am - 6:10 amMCI-SCL
16h 35m1 stop
Delta Logo
6:30 pm - 9:40 amSCL-MCI
18h 10m2 stops
$764Delta
Find Deal
Wed, Jan 7 - Wed, Jan 14
United Airlines Logo
7:50 am - 8:50 amJLN-SCL
22h 00m2 stops
United Airlines Logo
10:45 pm - 11:27 pmSCL-JLN
27h 42m2 stops
$768United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
LATAM Airlines Logo
1:55 pm - 6:10 amSTL-SCL
13h 15m1 stop
LATAM Airlines Logo
7:15 am - 11:41 pmSCL-STL
19h 26m3 stops
$768LATAM Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
LATAM Airlines Logo
10:35 am - 6:10 amMCI-SCL
16h 35m1 stop
LATAM Airlines Logo
1:40 pm - 9:40 amSCL-MCI
23h 00m2 stops
$774LATAM Airlines
Find Deal
Wed, Jan 7 - Wed, Jan 14
United Airlines Logo
7:50 am - 8:50 amJLN-SCL
22h 00m2 stops
United Airlines Logo
10:45 pm - 11:27 pmSCL-JLN
27h 42m2 stops
$818United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
American Airlines Logo
5:28 am - 7:55 amSTL-SCL
24h 27m1 stop
American Airlines Logo
9:55 pm - 11:56 pmSCL-STL
28h 01m1 stop
$866American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
Multiple Airlines Logo
7:15 pm - 4:55 amSTL-SCL
31h 40m3 stops
Multiple Airlines Logo
6:40 am - 11:01 amSCL-STL
31h 21m3 stops
$898Multiple Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8
American Airlines Logo
5:03 pm - 9:05 amSTL-SCL
14h 02m1 stop
American Airlines Logo
10:15 pm - 9:52 amSCL-STL
13h 37m1 stop
$944American Airlines
Find Deal
Mon, Mar 9 - Fri, Mar 20
Multiple Airlines Logo
7:15 pm - 4:55 amSTL-SCL
31h 40m3 stops
Multiple Airlines Logo
6:40 am - 3:29 pmSCL-STL
35h 49m3 stops
$994Multiple Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 18

LATAM Airlines flights from Missouri to Santiago

Our best LATAM Airlines deals on Missouri to Santiago flight tickets
LATAM Airlines
Dec 11
STL1:55 pmLambert-St Louis
13h 15m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
Dec 15
SCL7:15 amSantiago Arturo Merino Benitez
19h 26m
3 stops
STL11:41 pmLambert-St Louis
$768
Find similar
LATAM Airlines
Jan 7
MCI10:35 amKansas City
16h 35m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
Jan 14
SCL1:40 pmSantiago Arturo Merino Benitez
23h 00m
2 stops
MCI9:40 amKansas City
$774
Find similar
LATAM Airlines
Jan 7
MCI10:35 amKansas City
24h 55m
3 stops
SCL2:30 pmSantiago Arturo Merino Benitez
Jan 14
SCL1:40 pmSantiago Arturo Merino Benitez
23h 00m
2 stops
MCI9:40 amKansas City
$778
Find similar

United Airlines flights from Missouri to Santiago

Our best United Airlines deals on Missouri to Santiago flight tickets
United Airlines
Dec 4
JLN7:50 amJoplin
22h 00m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 8
SCL10:45 pmSantiago Arturo Merino Benitez
27h 42m
2 stops
JLN11:27 pmJoplin
$768
Find similar
United Airlines
Dec 4
JLN7:50 amJoplin
22h 00m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 8
SCL10:45 pmSantiago Arturo Merino Benitez
27h 42m
2 stops
JLN11:27 pmJoplin
$818
Find similar
United Airlines
Nov 1
STL6:43 pmLambert-St Louis
36h 07m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Nov 8
SCL10:45 pmSantiago Arturo Merino Benitez
16h 43m
2 stops
STL12:28 pmLambert-St Louis
$848
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Missouri to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

11:04 am-6:35 am

2 stops16h 31m

Santiago Arturo Merino Benitez

Mon 12/8

6:30 pm-1:00 pm

2 stops21h 30m

$764

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Wed 1/7

10:35 am-6:10 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Wed 1/14

6:30 pm-9:40 am

2 stops18h 10m

$764

JoplinSantiago

JLN - SCL

JLNSCL

Joplin

Thu 12/4

7:50 am-8:50 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Mon 12/8

10:45 pm-11:27 pm

2 stops27h 42m

$768

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 12/11

1:55 pm-6:10 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Mon 12/15

7:15 am-11:41 pm

3 stops19h 26m

$768

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Wed 1/7

10:35 am-6:10 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Wed 1/14

1:40 pm-9:40 am

2 stops23h 00m

$774

JoplinSantiago

JLN - SCL

JLNSCL

Joplin

Thu 12/4

7:50 am-8:50 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Mon 12/8

10:45 pm-11:27 pm

2 stops27h 42m

$818

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sat 10/4

5:28 am-7:55 am

1 stop24h 27m

Santiago Arturo Merino Benitez

Sat 10/11

9:55 pm-11:56 pm

1 stop28h 01m

$866

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sat 11/1

7:15 pm-4:55 am

3 stops31h 40m

Santiago Arturo Merino Benitez

Sat 11/8

6:40 am-11:01 am

3 stops31h 21m

$898

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/9

5:03 pm-9:05 am

1 stop14h 02m

Santiago Arturo Merino Benitez

Fri 3/20

10:15 pm-9:52 am

1 stop13h 37m

$944

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sat 11/1

7:15 pm-4:55 am

3 stops31h 40m

Santiago Arturo Merino Benitez

Tue 11/18

6:40 am-3:29 pm

3 stops35h 49m

$994

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from Missouri to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Missouri to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $772. If you don’t want to visit Santiago in October, then you should wait until September to fly from Missouri, when ticket prices are also cheap, with an average price of $843.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Missouri to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $971 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Missouri for as low as $902 on momondo.

Cheap Missouri to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santiago

Direct flights

None
There are no direct flights from Missouri to Santiago. There are no popular flight routes from Missouri to Santiago.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Missouri to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Missouri to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santiago

Compare and see reviews for airlines that fly from Missouri to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $762Free CancellationRating
7.5
1,849 reviews
Search LATAM Airlines flights
DeltaPriceFrom $802Free CancellationRating
7.9
7,964 reviews
Search Delta flights
United AirlinesPriceFrom $803Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $807Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Missouri.

Can I find flights from Missouri to Santiago with flexible booking policies on momondo?

Flights from Missouri to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Missouri to Santiago.

I’m not ready to book a flight from Missouri to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 10/19
Sun 10/26
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile