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Cheap flights from Missouri to Prague from $311

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Prague departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Prague

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
3:50 pm - 2:05 pm
STL
-
PRG
15h 15m1 stop
Lufthansa Logo
10:15 am - 11:59 pm
PRG
-
STL
20h 44m2 stops
$452Lufthansa
Wed, Jan 28 - Wed, Feb 4
Lufthansa Logo
3:50 pm - 11:10 am
STL
-
PRG
12h 20m1 stop
Lufthansa Logo
10:30 am - 10:58 pm
PRG
-
STL
19h 28m2 stops
$453Lufthansa
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
4:05 pm - 1:55 pm
STL
-
PRG
14h 50m2 stops
Multiple Airlines Logo
10:30 am - 3:15 pm
PRG
-
STL
35h 45m2 stops
$490Multiple Airlines
Tue, Jan 27 - Tue, Feb 3
Multiple Airlines Logo
4:05 pm - 1:55 pm
STL
-
PRG
14h 50m2 stops
Multiple Airlines Logo
8:15 pm - 3:29 pm
PRG
-
STL
50h 14m2 stops
$492Multiple Airlines
Wed, Jan 28 - Wed, Feb 4
British Airways Logo
5:20 pm - 10:50 pm
STL
-
PRG
22h 30m2 stops
British Airways Logo
6:50 am - 9:15 pm
PRG
-
STL
21h 25m2 stops
$495British Airways
Sun, Jan 25 - Sun, Feb 1
British Airways Logo
1:56 pm - 8:45 pm
MCI
-
PRG
23h 49m2 stops
British Airways Logo
9:20 pm - 9:06 pm
PRG
-
MCI
30h 46m2 stops
$495British Airways
Sun, Jan 11 - Tue, Jan 20
United Airlines Logo
8:30 am - 10:50 am
STL
-
PRG
19h 20m2 stops
United Airlines Logo
7:25 am - 3:29 pm
PRG
-
STL
39h 04m2 stops
$506United Airlines
Fri, Feb 6 - Tue, Feb 10
Delta Logo
6:25 am - 9:05 am
STL
-
PRG
19h 40m2 stops
Delta Logo
6:00 am - 8:43 pm
PRG
-
STL
21h 43m2 stops
$507Delta
Thu, Jan 22 - Sun, Feb 1
Delta Logo
9:59 am - 11:40 am
MCI
-
PRG
18h 41m2 stops
Delta Logo
11:35 am - 11:54 pm
PRG
-
MCI
19h 19m2 stops
$507Delta
Tue, Feb 17 - Mon, Feb 23
United Airlines Logo
11:29 am - 4:05 pm
MCI
-
PRG
21h 36m2 stops
United Airlines Logo
7:35 am - 7:42 pm
PRG
-
MCI
19h 07m2 stops
$508United Airlines
Wed, Feb 11 - Fri, Feb 20

Lufthansa flights from Missouri to Prague

Our best Lufthansa deals on Missouri to Prague flight tickets
Lufthansa
Jan 28
STL3:50 pmLambert-St Louis
15h 15m
1 stop
PRG2:05 pmVáclav Havel Prague
Feb 4
PRG10:15 amVáclav Havel Prague
20h 44m
2 stops
STL11:59 pmLambert-St Louis
$452
Find similar
Lufthansa
Jan 26
STL6:40 pmLambert-St Louis
14h 25m
2 stops
PRG4:05 pmVáclav Havel Prague
Feb 1
PRG10:30 amVáclav Havel Prague
19h 28m
2 stops
STL10:58 pmLambert-St Louis
$494
Find similar
Lufthansa
Jan 25
STL3:50 pmLambert-St Louis
12h 20m
1 stop
PRG11:10 amVáclav Havel Prague
Feb 1
PRG10:30 amVáclav Havel Prague
19h 28m
2 stops
STL10:58 pmLambert-St Louis
$507
Find similar

British Airways flights from Missouri to Prague

Our best British Airways deals on Missouri to Prague flight tickets
British Airways
Jan 25
STL5:20 pmLambert-St Louis
22h 30m
2 stops
PRG10:50 pmVáclav Havel Prague
Feb 1
PRG6:50 amVáclav Havel Prague
21h 25m
2 stops
STL9:15 pmLambert-St Louis
$495
Find similar
British Airways
Dec 31
MCI4:59 pmKansas City
17h 31m
2 stops
PRG5:30 pmVáclav Havel Prague
Jan 14
PRG9:30 pmVáclav Havel Prague
32h 42m
2 stops
MCI11:12 pmKansas City
$695
Find similar
British Airways
Apr 24
MCI6:08 pmKansas City
15h 42m
2 stops
PRG4:50 pmVáclav Havel Prague
May 8
PRG7:10 amVáclav Havel Prague
23h 30m
2 stops
MCI11:40 pmKansas City
$744
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 1/28

3:50 pm-2:05 pm

1 stop15h 15m

Václav Havel Prague

Wed 2/4

10:15 am-11:59 pm

2 stops20h 44m

$452

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 1/25

3:50 pm-11:10 am

1 stop12h 20m

Václav Havel Prague

Sun 2/1

10:30 am-10:58 pm

2 stops19h 28m

$453

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Tue 1/27

4:05 pm-1:55 pm

2 stops14h 50m

Václav Havel Prague

Tue 2/3

10:30 am-3:15 pm

2 stops35h 45m

$490

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 1/28

4:05 pm-1:55 pm

2 stops14h 50m

Václav Havel Prague

Wed 2/4

8:15 pm-3:29 pm

2 stops50h 14m

$492

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 1/25

5:20 pm-10:50 pm

2 stops22h 30m

Václav Havel Prague

Sun 2/1

6:50 am-9:15 pm

2 stops21h 25m

$495

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

1:56 pm-8:45 pm

2 stops23h 49m

Václav Havel Prague

Tue 1/20

9:20 pm-9:06 pm

2 stops30h 46m

$495

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 2/6

8:30 am-10:50 am

2 stops19h 20m

Václav Havel Prague

Tue 2/10

7:25 am-3:29 pm

2 stops39h 04m

$506

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Thu 1/22

6:25 am-9:05 am

2 stops19h 40m

Václav Havel Prague

Sun 2/1

6:00 am-8:43 pm

2 stops21h 43m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Tue 2/17

9:59 am-11:40 am

2 stops18h 41m

Václav Havel Prague

Mon 2/23

11:35 am-11:54 pm

2 stops19h 19m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 2/11

11:29 am-4:05 pm

2 stops21h 36m

Václav Havel Prague

Fri 2/20

7:35 am-7:42 pm

2 stops19h 07m

$508

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Prague from

How to get the cheapest flight ticket from Missouri to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Prague?

In general, March is the cheapest month to fly from Missouri to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $655. If you are unable to visit Prague during the month of March, then departing from Missouri during the month January is also very affordable. Most momondo users find prices during this month for around $683.

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from Missouri to Prague is on a Thursday. Travelers who choose to depart for Prague on a Thursday will often find tickets for as low as $983. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Missouri to Prague for around $1,216.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the morning. momondo users have found flights departing from Missouri to Prague in the morning for as low as $1,013. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $1,216. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Missouri to Prague flights?

You could potentially save up to 21% on your flight if you consider stops on a Missouri to Prague flight.

Cheap Missouri to Prague flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Prague

Fastest flight time

15h 15m

Direct flights

None
The fastest flight from Missouri to Prague takes 15h 15m
There are no direct flights from Missouri to Prague. There are no popular flight routes from Missouri to Prague.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Václav Havel Prague Airport?

    Prices for flights from Missouri to Václav Havel Prague Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Václav Havel Prague Airport?

  • How old do you have to be to fly from Missouri to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Prague

Compare and see reviews for airlines that fly from Missouri to Prague with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $383Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
LufthansaPriceFrom $556Free CancellationRating
6.8
7,628 reviews
Search Lufthansa flights
British AirwaysPriceFrom $582Free CancellationRating
6.7
7,575 reviews
Search British Airways flights
DeltaPriceFrom $608Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $711Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
Air CanadaPriceFrom $745Free CancellationRating
7.1
10,525 reviews
Search Air Canada flights

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Prague?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Missouri to Prague. momondo saves you time and could save you money on your trip.

Can I find flights from Missouri to Prague with flexible booking policies on momondo?

All flight searches from Missouri to Prague on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Prague right now. Can momondo alert me if prices change?

Price alerts on flights to Prague from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Prague trip

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Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo
United Airlines
Delta
Lufthansa
British Airways
American Airlines
Air Canada