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Cheap flights from Missouri to Guayaquil from $427

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Guayaquil departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Missouri to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
2:47 pm - 11:43 pmSTL-GYE
7h 56m1 stop
Spirit Airlines Logo
12:49 am - 1:52 pmGYE-STL
14h 03m1 stop
$427Spirit Airlines
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Thu, Dec 4 - Wed, Dec 10
Multiple Airlines Logo
12:13 pm - 5:20 amMCI-GYE
40h 07m2 stops
Multiple Airlines Logo
12:49 am - 5:56 pmGYE-MCI
18h 07m1 stop
$449Multiple Airlines
Find Deal
Fri, Dec 5 - Thu, Dec 11
United Airlines Logo
6:15 am - 5:36 pmSTL-GYE
34h 21m2 stops
United Airlines Logo
8:30 am - 4:04 pmGYE-STL
32h 34m2 stops
$587United Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
United Airlines Logo
6:15 am - 5:36 pmSTL-GYE
34h 21m2 stops
United Airlines Logo
12:20 pm - 10:14 pmGYE-STL
34h 54m2 stops
$606United Airlines
Find Deal
Thu, Dec 4 - Fri, Feb 20
Delta Logo
6:00 am - 2:05 amSTL-GYE
20h 05m2 stops
Delta Logo
8:40 pm - 11:38 pmGYE-STL
26h 58m2 stops
$658Delta
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Wed, Apr 29 - Sun, May 3
Delta Logo
10:45 am - 7:20 amSTL-GYE
20h 35m2 stops
Delta Logo
8:40 pm - 8:07 amGYE-STL
35h 27m2 stops
$663Delta
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Wed, Apr 29 - Sun, May 3
LATAM Airlines Logo
6:00 am - 6:53 amSTL-GYE
23h 53m2 stops
LATAM Airlines Logo
8:42 pm - 11:05 amGYE-STL
15h 23m2 stops
$770LATAM Airlines
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Sun, Dec 14 - Wed, Jan 14
American Airlines Logo
5:35 am - 1:33 pmSTL-GYE
7h 58m1 stop
American Airlines Logo
6:40 am - 9:35 pmGYE-STL
14h 55m1 stop
$886American Airlines
Find Deal
Wed, Apr 29 - Sun, May 3
American Airlines Logo
6:28 am - 8:55 pmSTL-GYE
14h 27m2 stops
American Airlines Logo
6:40 am - 9:35 pmGYE-STL
14h 55m1 stop
$891American Airlines
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Wed, Apr 29 - Sun, May 3
LATAM Airlines Logo
11:19 am - 8:33 amSTL-GYE
20h 14m2 stops
LATAM Airlines Logo
5:56 pm - 8:53 amGYE-STL
15h 57m2 stops
$1,195LATAM Airlines
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Sat, Dec 13 - Tue, Jan 13

Delta flights from Missouri to Guayaquil

Our best Delta deals on Missouri to Guayaquil flight tickets
Delta
Apr 29
STL6:00 amLambert-St Louis
20h 05m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
May 3
GYE8:40 pmGuayaquil Jose Joaquin de Olmedo
26h 58m
2 stops
STL11:38 pmLambert-St Louis
$658
Find similar
Delta
Apr 29
STL10:45 amLambert-St Louis
20h 35m
2 stops
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
May 3
GYE8:40 pmGuayaquil Jose Joaquin de Olmedo
35h 27m
2 stops
STL8:07 amLambert-St Louis
$663
Find similar
Delta
May 3
MCI6:00 amKansas City
25h 20m
2 stops
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
May 5
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
25h 58m
1 stop
MCI5:58 pmKansas City
$713
Find similar

LATAM Airlines flights from Missouri to Guayaquil

Our best LATAM Airlines deals on Missouri to Guayaquil flight tickets
LATAM Airlines
Dec 14
STL6:00 amLambert-St Louis
23h 53m
2 stops
GYE6:53 amGuayaquil Jose Joaquin de Olmedo
Jan 14
GYE8:42 pmGuayaquil Jose Joaquin de Olmedo
15h 23m
2 stops
STL11:05 amLambert-St Louis
$770
Find similar
LATAM Airlines
Dec 13
STL11:19 amLambert-St Louis
20h 14m
2 stops
GYE8:33 amGuayaquil Jose Joaquin de Olmedo
Jan 13
GYE5:56 pmGuayaquil Jose Joaquin de Olmedo
15h 57m
2 stops
STL8:53 amLambert-St Louis
$1,195
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

2:47 pm-11:43 pm

1 stop7h 56m

Guayaquil Jose Joaquin de Olmedo

Wed 12/10

12:49 am-1:52 pm

1 stop14h 03m

$427

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Fri 12/5

12:13 pm-5:20 am

2 stops40h 07m

Guayaquil Jose Joaquin de Olmedo

Thu 12/11

12:49 am-5:56 pm

1 stop18h 07m

$449

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

6:15 am-5:36 pm

2 stops34h 21m

Guayaquil Jose Joaquin de Olmedo

Thu 12/11

8:30 am-4:04 pm

2 stops32h 34m

$587

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

6:15 am-5:36 pm

2 stops34h 21m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

12:20 pm-10:14 pm

2 stops34h 54m

$606

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 4/29

6:00 am-2:05 am

2 stops20h 05m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

8:40 pm-11:38 pm

2 stops26h 58m

$658

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 4/29

10:45 am-7:20 am

2 stops20h 35m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

8:40 pm-8:07 am

2 stops35h 27m

$663

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 12/14

6:00 am-6:53 am

2 stops23h 53m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

8:42 pm-11:05 am

2 stops15h 23m

$770

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 4/29

5:35 am-1:33 pm

1 stop7h 58m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

6:40 am-9:35 pm

1 stop14h 55m

$886

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 4/29

6:28 am-8:55 pm

2 stops14h 27m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

6:40 am-9:35 pm

1 stop14h 55m

$891

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 12/13

11:19 am-8:33 am

2 stops20h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 1/13

5:56 pm-8:53 am

2 stops15h 57m

$1,195

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Missouri to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Missouri to Guayaquil is on a Wednesday. Travelers who choose to depart for Guayaquil on a Wednesday will often find tickets for as low as $529. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $594.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the afternoon when flights can be purchased for as low as $554. Flights to Guayaquil are more costly in the morning, with an average ticket price of $595. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Missouri to Guayaquil flights?

You could potentially save up to 6% on your flight if you consider stops on a Missouri to Guayaquil flight.

Cheap Missouri to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Guayaquil

Direct flights

None
There are no direct flights from Missouri to Guayaquil. There are no popular flight routes from Missouri to Guayaquil.
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  • When did momondo last update prices for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Guayaquil

Compare and see reviews for airlines that fly from Missouri to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $516Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Guayaquil?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Guayaquil. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Guayaquil with flexible booking policies on momondo?

All flight searches from Missouri to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Guayaquil?

Once all potential Missouri to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Missouri and alert you when they change.

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