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Cheap flights from Missouri to Guayaquil from $222

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Guayaquil departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
11:26 am - 12:21 am
MCI
-
GYE
11h 55m1 stop
Spirit Airlines Logo
1:26 am - 10:31 am
GYE
-
MCI
10h 05m1 stop
$222Spirit Airlines
Thu, Jan 29 - Wed, Feb 4
Multiple Airlines Logo
11:26 am - 12:21 am
MCI
-
GYE
11h 55m1 stop
Multiple Airlines Logo
6:55 pm - 10:31 am
GYE
-
MCI
40h 36m2 stops
$308Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Spirit Airlines Logo
5:04 pm - 12:21 am
MCI
-
GYE
30h 17m3 stops
Spirit Airlines Logo
1:26 am - 10:31 am
GYE
-
MCI
10h 05m1 stop
$354Spirit Airlines
Thu, Jan 29 - Wed, Feb 4
Spirit Airlines Logo
5:04 pm - 12:21 am
MCI
-
GYE
30h 17m3 stops
Spirit Airlines Logo
1:26 am - 4:09 pm
GYE
-
MCI
39h 43m3 stops
$467Spirit Airlines
Thu, Jan 29 - Wed, Feb 4
Spirit Airlines Logo
5:04 pm - 12:21 am
MCI
-
GYE
30h 17m3 stops
Spirit Airlines Logo
1:26 am - 4:09 pm
GYE
-
MCI
39h 43m3 stops
$567Spirit Airlines
Sat, Jan 10 - Tue, Jan 20
United Airlines Logo
6:00 am - 11:42 pm
STL
-
GYE
16h 42m2 stops
United Airlines Logo
8:34 am - 9:22 am
GYE
-
STL
25h 48m2 stops
$587United Airlines
Mon, Feb 2 - Mon, Feb 9
American Airlines Logo
8:13 am - 11:22 pm
STL
-
GYE
14h 09m2 stops
American Airlines Logo
7:15 am - 11:59 pm
GYE
-
STL
17h 44m1 stop
$589American Airlines
Mon, Feb 2 - Mon, Feb 9
American Airlines Logo
6:02 pm - 11:22 pm
STL
-
GYE
28h 20m1 stop
American Airlines Logo
7:15 am - 11:59 pm
GYE
-
STL
17h 44m1 stop
$595American Airlines
Mon, Feb 2 - Mon, Feb 9
American Airlines Logo
5:00 am - 1:30 pm
MCI
-
GYE
8h 30m1 stop
American Airlines Logo
2:30 pm - 12:39 am
GYE
-
MCI
10h 09m1 stop
$633American Airlines
Sat, Mar 21 - Sat, Mar 28
United Airlines Logo
4:25 pm - 11:41 pm
MCI
-
GYE
31h 16m2 stops
United Airlines Logo
8:32 am - 9:29 am
GYE
-
MCI
24h 57m2 stops
$665United Airlines
Sat, Mar 21 - Sat, Mar 28

Spirit Airlines flights from Missouri to Guayaquil

Our best Spirit Airlines deals on Missouri to Guayaquil flight tickets
Spirit Airlines
Jan 29
MCI11:26 amKansas City
11h 55m
1 stop
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 4
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
10h 05m
1 stop
MCI10:31 amKansas City
$222
Find similar
Spirit Airlines
Jan 29
MCI5:04 pmKansas City
30h 17m
3 stops
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 4
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
10h 05m
1 stop
MCI10:31 amKansas City
$354
Find similar
Spirit Airlines
Jan 29
MCI5:04 pmKansas City
30h 17m
3 stops
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 4
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
39h 43m
3 stops
MCI4:09 pmKansas City
$467
Find similar

United Airlines flights from Missouri to Guayaquil

Our best United Airlines deals on Missouri to Guayaquil flight tickets
United Airlines
Feb 2
STL6:00 amLambert-St Louis
16h 42m
2 stops
GYE11:42 pmGuayaquil Jose Joaquin de Olmedo
Feb 9
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
25h 48m
2 stops
STL9:22 amLambert-St Louis
$587
Find similar
United Airlines
Mar 21
MCI4:25 pmKansas City
31h 16m
2 stops
GYE11:41 pmGuayaquil Jose Joaquin de Olmedo
Mar 28
GYE8:32 amGuayaquil Jose Joaquin de Olmedo
24h 57m
2 stops
MCI9:29 amKansas City
$665
Find similar
United Airlines
Jan 25
MCI4:25 pmKansas City
27h 21m
2 stops
GYE8:46 pmGuayaquil Jose Joaquin de Olmedo
Jan 29
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
33h 19m
2 stops
MCI4:53 pmKansas City
$694
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Missouri to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 1/29

11:26 am-12:21 am

1 stop11h 55m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-10:31 am

1 stop10h 05m

$222

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 1/29

11:26 am-12:21 am

1 stop11h 55m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

6:55 pm-10:31 am

2 stops40h 36m

$308

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 1/29

5:04 pm-12:21 am

3 stops30h 17m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-10:31 am

1 stop10h 05m

$354

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 1/29

5:04 pm-12:21 am

3 stops30h 17m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-4:09 pm

3 stops39h 43m

$467

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sat 1/10

5:04 pm-12:21 am

3 stops30h 17m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

1:26 am-4:09 pm

3 stops39h 43m

$567

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 2/2

6:00 am-11:42 pm

2 stops16h 42m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

8:34 am-9:22 am

2 stops25h 48m

$587

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 2/2

8:13 am-11:22 pm

2 stops14h 09m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

7:15 am-11:59 pm

1 stop17h 44m

$589

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 2/2

6:02 pm-11:22 pm

1 stop28h 20m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

7:15 am-11:59 pm

1 stop17h 44m

$595

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sat 3/21

5:00 am-1:30 pm

1 stop8h 30m

Guayaquil Jose Joaquin de Olmedo

Sat 3/28

2:30 pm-12:39 am

1 stop10h 09m

$633

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sat 3/21

4:25 pm-11:41 pm

2 stops31h 16m

Guayaquil Jose Joaquin de Olmedo

Sat 3/28

8:32 am-9:29 am

2 stops24h 57m

$665

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from Missouri to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Missouri to Guayaquil is on a Wednesday. Travelers who choose to depart for Guayaquil on a Wednesday will often find tickets for as low as $529. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $594.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the afternoon when flights can be purchased for as low as $554. Flights to Guayaquil are more costly in the morning, with an average ticket price of $595. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Missouri to Guayaquil flights?

You could potentially save up to 9% on your flight if you consider stops on a Missouri to Guayaquil flight.

Cheap Missouri to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Guayaquil

Fastest flight time

10h 49m

Direct flights

None
The fastest flight from Missouri to Guayaquil takes 10h 49m
There are no direct flights from Missouri to Guayaquil. There are no popular flight routes from Missouri to Guayaquil.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Missouri to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Guayaquil

Compare and see reviews for airlines that fly from Missouri to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $516Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Guayaquil?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Guayaquil. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Guayaquil with flexible booking policies on momondo?

All flight searches from Missouri to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Guayaquil?

Once all potential Missouri to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Missouri and alert you when they change.

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