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Cheap flights from Mississippi to Panama from $275

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama departing on 8/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Mississippi to Panama

Cheap round-trip flights

American Airlines Logo
4:42 pm - 2:31 pmMOB-PTY
21h 49m2 stops
American Airlines Logo
3:31 pm - 5:23 pmPTY-MOB
25h 52m2 stops
$492American Airlines
Find Deal
jue., sep. 25 - jue., oct. 2
American Airlines Logo
6:00 am - 2:03 pmMEM-PTY
8h 03m1 stop
American Airlines Logo
3:15 pm - 11:59 pmPTY-MEM
8h 44m1 stop
$509American Airlines
Find Deal
vie., oct. 17 - sáb., oct. 25
American Airlines Logo
6:00 pm - 2:31 pmJAN-PTY
20h 31m2 stops
American Airlines Logo
3:31 pm - 9:56 amPTY-JAN
18h 25m2 stops
$512American Airlines
Find Deal
vie., sep. 26 - vie., oct. 3
American Airlines Logo
6:56 pm - 2:03 pmMEM-PTY
19h 07m2 stops
American Airlines Logo
3:15 pm - 11:59 pmPTY-MEM
8h 44m1 stop
$514American Airlines
Find Deal
dom., oct. 12 - vie., oct. 17
United Airlines Logo
7:05 am - 6:37 pmGPT-PTY
11h 32m1 stop
United Airlines Logo
3:30 pm - 1:27 pmPTY-GPT
21h 57m1 stop
$515United Airlines
Find Deal
lun., sep. 8 - lun., sep. 15
United Airlines Logo
9:20 am - 2:14 pmMOB-PTY
28h 54m1 stop
United Airlines Logo
10:00 am - 9:48 pmPTY-MOB
11h 48m1 stop
$516United Airlines
Find Deal
jue., sep. 25 - jue., oct. 2
Delta Logo
6:25 am - 12:55 pmMEM-PTY
6h 30m1 stop
Delta Logo
2:10 pm - 11:03 pmPTY-MEM
8h 53m1 stop
$529Delta
Find Deal
jue., sep. 11 - jue., sep. 18
Logo
9:55 am - 8:55 amMEM-PTY
23h 00m2 stops
Logo
3:25 am - 11:08 pmPTY-MEM
19h 43m2 stops
$530
Find Deal
vie., oct. 17 - vie., oct. 24
Logo
9:55 am - 8:55 amMEM-PTY
23h 00m2 stops
Logo
5:25 pm - 11:08 pmPTY-MEM
29h 43m3 stops
$537
Find Deal
vie., oct. 17 - sáb., oct. 25
Delta Logo
6:00 am - 12:50 pmGPT-PTY
6h 50m1 stop
Delta Logo
2:05 pm - 9:38 pmPTY-GPT
7h 33m1 stop
$567Delta
Find Deal
sáb., ago. 30 - jue., sep. 4

American Airlines flights from Mississippi to Panama

Our best American Airlines deals on Mississippi to Panama flight tickets
American Airlines
Sep 25
MOB4:42 pmMobile
21h 49m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 2
PTY3:31 pmPanama City Tocumen Intl
25h 52m
2 stops
MOB5:23 pmMobile
$492
Find similar
American Airlines
Oct 17
MEM6:00 amMemphis
8h 03m
1 stop
PTY2:03 pmPanama City Tocumen Intl
Oct 25
PTY3:15 pmPanama City Tocumen Intl
8h 44m
1 stop
MEM11:59 pmMemphis
$509
Find similar
American Airlines
Sep 26
JAN6:00 pmJackson-Evers Intl
20h 31m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 3
PTY3:31 pmPanama City Tocumen Intl
18h 25m
2 stops
JAN9:56 amJackson-Evers Intl
$512
Find similar

United Airlines flights from Mississippi to Panama

Our best United Airlines deals on Mississippi to Panama flight tickets
United Airlines
Sep 8
GPT7:05 amGulfport Biloxi Regional
11h 32m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 15
PTY3:30 pmPanama City Tocumen Intl
21h 57m
1 stop
GPT1:27 pmGulfport Biloxi Regional
$515
Find similar
United Airlines
Sep 25
MOB9:20 amMobile
28h 54m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Oct 2
PTY10:00 amPanama City Tocumen Intl
11h 48m
1 stop
MOB9:48 pmMobile
$516
Find similar
United Airlines
Sep 26
JAN5:05 pmJackson-Evers Intl
21h 09m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Oct 3
PTY10:00 amPanama City Tocumen Intl
11h 58m
1 stop
JAN9:58 pmJackson-Evers Intl
$535
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 13, 2025.
Use the filters below to find and compare flights from Mississippi to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MobilePanama City

MOB - PTY

MOBPTY

Mobile

jue. 9/25

4:42 pm-2:31 pm

2 stops21h 49m

Panama City Tocumen Intl

jue. 10/2

3:31 pm-5:23 pm

2 stops25h 52m

$492

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

vie. 10/17

6:00 am-2:03 pm

1 stop8h 03m

Panama City Tocumen Intl

sáb. 10/25

3:15 pm-11:59 pm

1 stop8h 44m

$509

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

vie. 9/26

6:00 pm-2:31 pm

2 stops20h 31m

Panama City Tocumen Intl

vie. 10/3

3:31 pm-9:56 am

2 stops18h 25m

$512

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

dom. 10/12

6:56 pm-2:03 pm

2 stops19h 07m

Panama City Tocumen Intl

vie. 10/17

3:15 pm-11:59 pm

1 stop8h 44m

$514

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

lun. 9/8

7:05 am-6:37 pm

1 stop11h 32m

Panama City Tocumen Intl

lun. 9/15

3:30 pm-1:27 pm

1 stop21h 57m

$515

MobilePanama City

MOB - PTY

MOBPTY

Mobile

jue. 9/25

9:20 am-2:14 pm

1 stop28h 54m

Panama City Tocumen Intl

jue. 10/2

10:00 am-9:48 pm

1 stop11h 48m

$516

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

jue. 9/11

6:25 am-12:55 pm

1 stop6h 30m

Panama City Tocumen Intl

jue. 9/18

2:10 pm-11:03 pm

1 stop8h 53m

$529

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

vie. 10/17

9:55 am-8:55 am

2 stops23h 00m

Panama City Tocumen Intl

vie. 10/24

3:25 am-11:08 pm

2 stops19h 43m

$530

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

vie. 10/17

9:55 am-8:55 am

2 stops23h 00m

Panama City Tocumen Intl

sáb. 10/25

5:25 pm-11:08 pm

3 stops29h 43m

$537

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

sáb. 8/30

6:00 am-12:50 pm

1 stop6h 50m

Panama City Tocumen Intl

jue. 9/4

2:05 pm-9:38 pm

1 stop7h 33m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Mississippi to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

According to our data, Saturday is the cheapest day to fly to Panama from Mississippi. The lowest ticket price found for a Saturday departure recently was $417. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Mississippi to Panama for around $1,055.

Cheap Mississippi to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama

Best Price Found

$275

Fastest flight time

6h 30m

Direct flights

None

Airports in Panama

1 airport
The best one-way flight to Panama from Mississippi in the past 72 hours is $275. The best round-trip flight deal from Mississippi to Panama found on momondo in the last 72 hours is $492.
The fastest flight from Mississippi to Panama takes 6h 30m
There are no direct flights from Mississippi to Panama. Popular non-direct routes for this connection are Jackson-Evers Intl Airport - Panama City Tocumen Intl Airport, Memphis Airport - Panama City Tocumen Intl Airport and Mobile Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Panama?

    Prices for flights from Mississippi to Panama were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama?

  • How old do you have to be to fly from Mississippi to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama

Compare and see reviews for airlines that fly from Mississippi to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
8,920 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mississippi to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Mississippi to Panama with flexible booking policies on momondo?

Flights from Mississippi to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mississippi to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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lun. 8/18
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