What is the cheapest airline that flies from Mississippi to Panama?

United Airlines, American Airlines, and Delta are the most popular carriers operating from Mississippi to Panama

How long is the flight from Mississippi to Panama?

Flight times from Mississippi to Panama vary, but if you’re flying out of Jackson and flying into Panama City (one of the most popular routes), then the duration is 6h 45m on average. Another popular route from Mississippi to Panama is flying from Gulfport to Panama City, which will take roughly 7h 21m. Keep in mind that layovers or delays could extend your travel time.

When did momondo last update prices for flights from Mississippi to Panama?

Prices for flights from Mississippi to Panama were last updated today.

How many operators does momondo search for flights from Mississippi to Panama?

As of October 2025, there are 3 operators available to choose from for flights from Mississippi to Panama.

How old do you have to be to fly from Mississippi to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$240 Cheap Flights from Mississippi to Panama in 2025/26

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Find the cheapest flights from Mississippi to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:40 am - 2:45 pmMEM-PTY

7h 05m1 stop

4:41 pm - 9:13 amPTY-MEM

17h 32m1 stop

$490United Airlines

Find Deal

Wed, Dec 10 - Wed, Jan 14

3:44 pm - 1:47 pmMEM-PTY

21h 03m2 stops

2:30 pm - 8:35 amPTY-MEM

19h 05m2 stops

$494American Airlines

Find Deal

Wed, Dec 10 - Fri, Feb 13

5:11 pm - 2:45 pmGPT-PTY

20h 34m1 stop

8:55 am - 4:03 pmPTY-GPT

8h 08m1 stop

$495United Airlines

Find Deal

Wed, Dec 10 - Sun, Dec 21

6:13 pm - 3:42 pmGPT-PTY

20h 29m2 stops

2:53 pm - 12:16 pmPTY-GPT

22h 23m2 stops

$497American Airlines

Find Deal

Wed, Dec 10 - Sun, Dec 21

6:29 pm - 1:27 pmMEM-PTY

17h 58m1 stop

2:30 pm - 11:14 pmPTY-MEM

9h 44m1 stop

$500American Airlines

Find Deal

Mon, Feb 9 - Fri, Feb 13

5:40 am - 2:21 pmJAN-PTY

7h 41m1 stop

8:05 am - 5:21 pmPTY-JAN

10h 16m1 stop

$508Delta

Find Deal

Sat, Dec 6 - Sat, Dec 13

7:00 am - 12:45 amMEM-PTY

17h 45m2 stops

5:50 pm - 11:08 pmPTY-MEM

29h 18m2 stops

$573Multiple Airlines

Find Deal

Wed, Oct 22 - Sun, Oct 26

6:17 pm - 2:00 pmMEM-PTY

18h 43m3 stops

5:55 pm - 6:15 pmPTY-MEM

25h 20m2 stops

$577Multiple Airlines

Find Deal

Sat, Feb 7 - Sat, Feb 21

5:59 pm - 8:00 pmMOB-PTY

25h 01m1 stop

8:00 am - 8:34 amPTY-MOB

25h 34m1 stop

$980Delta

Find Deal

Mon, Dec 22 - Sat, Dec 27

5:59 pm - 9:20 amMOB-PTY

38h 21m2 stops

10:20 am - 11:20 pmPTY-MOB

38h 00m2 stops

$5,097WestJet

Find Deal

Tue, Dec 23 - Sun, Dec 28

American Airlines flights from Mississippi to Panama

Our best American Airlines deals on Mississippi to Panama flight tickets

American Airlines

Dec 10

MEM3:44 pmMemphis

21h 03m

2 stops

PTY1:47 pmPanama City Tocumen Intl

Feb 13

PTY2:30 pmPanama City Tocumen Intl

19h 05m

2 stops

MEM8:35 amMemphis

$494

Find similar

American Airlines

Dec 10

GPT6:13 pmGulfport Biloxi Regional

20h 29m

2 stops

PTY3:42 pmPanama City Tocumen Intl

Dec 21

PTY2:53 pmPanama City Tocumen Intl

22h 23m

2 stops

GPT12:16 pmGulfport Biloxi Regional

$497

Find similar

American Airlines

Feb 9

MEM6:29 pmMemphis

17h 58m

1 stop

PTY1:27 pmPanama City Tocumen Intl

Feb 13

PTY2:30 pmPanama City Tocumen Intl

9h 44m

1 stop

MEM11:14 pmMemphis

$500

Find similar

United Airlines flights from Mississippi to Panama

Our best United Airlines deals on Mississippi to Panama flight tickets

United Airlines

Dec 10

MEM6:40 amMemphis

7h 05m

1 stop

PTY2:45 pmPanama City Tocumen Intl

Jan 14

PTY4:41 pmPanama City Tocumen Intl

17h 32m

1 stop

MEM9:13 amMemphis

$490

Find similar

United Airlines

Dec 10

GPT5:11 pmGulfport Biloxi Regional

20h 34m

1 stop

PTY2:45 pmPanama City Tocumen Intl

Dec 21

PTY8:55 amPanama City Tocumen Intl

8h 08m

1 stop

GPT4:03 pmGulfport Biloxi Regional

$495

Find similar

United Airlines

Apr 6

GPT5:15 pmGulfport Biloxi Regional

20h 59m

1 stop

PTY2:14 pmPanama City Tocumen Intl

Apr 12

PTY7:55 amPanama City Tocumen Intl

11h 47m

1 stop

GPT7:42 pmGulfport Biloxi Regional

$535

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 12/10

6:40 am-2:45 pm

1 stop7h 05m

Panama City Tocumen Intl

Wed 1/14

4:41 pm-9:13 am

1 stop17h 32m

$490

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 12/10

3:44 pm-1:47 pm

2 stops21h 03m

Panama City Tocumen Intl

Fri 2/13

2:30 pm-8:35 am

2 stops19h 05m

$494

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 12/10

5:11 pm-2:45 pm

1 stop20h 34m

Panama City Tocumen Intl

Sun 12/21

8:55 am-4:03 pm

1 stop8h 08m

$495

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 12/10

6:13 pm-3:42 pm

2 stops20h 29m

Panama City Tocumen Intl

Sun 12/21

2:53 pm-12:16 pm

2 stops22h 23m

$497

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 2/9

6:29 pm-1:27 pm

1 stop17h 58m

Panama City Tocumen Intl

Fri 2/13

2:30 pm-11:14 pm

1 stop9h 44m

$500

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sat 12/6

5:40 am-2:21 pm

1 stop7h 41m

Panama City Tocumen Intl

Sat 12/13

8:05 am-5:21 pm

1 stop10h 16m

$508

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 10/22

7:00 am-12:45 am

2 stops17h 45m

Panama City Tocumen Intl

Sun 10/26

5:50 pm-11:08 pm

2 stops29h 18m

$573

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 2/7

6:17 pm-2:00 pm

3 stops18h 43m

Panama City Tocumen Intl

Sat 2/21

5:55 pm-6:15 pm

2 stops25h 20m

$577

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Mon 12/22

5:59 pm-8:00 pm

1 stop25h 01m

Panama City Tocumen Intl

Sat 12/27

8:00 am-8:34 am

1 stop25h 34m

$980

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Tue 12/23

5:59 pm-9:20 am

2 stops38h 21m

Panama City Tocumen Intl

Sun 12/28

10:20 am-11:20 pm

2 stops38h 00m

$5,097

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Mississippi to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest day to depart on your flight to Panama?

According to our data, Saturday is the cheapest day to fly to Panama from Mississippi. The lowest ticket price found for a Saturday departure recently was $417. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Mississippi to Panama for around $1,055.

Cheap Mississippi to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama

Direct flights	None

There are no direct flights from Mississippi to Panama. There are no popular flight routes from Mississippi to Panama.

Search flight deals

When did momondo last update prices for flights from Mississippi to Panama?
Prices for flights from Mississippi to Panama were last updated today.
How many operators does momondo search for flights from Mississippi to Panama?
As of October 2025, there are 3 operators available to choose from for flights from Mississippi to Panama.
How old do you have to be to fly from Mississippi to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama

Compare and see reviews for airlines that fly from Mississippi to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $445	Free Cancellation	Rating 7.4 8,968 reviews		Search United Airlines flights

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Why should I use momondo to find a flight deal from Mississippi to Panama?

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Can I find flights from Mississippi to Panama with flexible booking policies on momondo?

Flights from Mississippi to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mississippi to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.