Cheap flights from Mississippi to Panama from $227

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama departing on 6/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:46 am - 6:37 pm
MEM
-
PTY
6h 51m
1 stop
United Airlines Logo
7:55 am - 6:12 pm
PTY
-
MEM
10h 17m
1 stop
$467United Airlines
Tue, Jul 28 - Thu, Jul 30
United Airlines Logo
4:08 pm - 4:04 am
MEM
-
PTY
11h 56m
1 stop
United Airlines Logo
3:30 pm - 11:05 am
PTY
-
MEM
19h 35m
2 stops
$471United Airlines
Tue, Jul 28 - Thu, Jul 30
United Airlines Logo
7:00 am - 6:37 pm
MEM
-
PTY
11h 37m
1 stop
United Airlines Logo
7:55 am - 10:06 pm
PTY
-
MEM
14h 11m
1 stop
$501United Airlines
Sat, Aug 1 - Thu, Aug 6
United Airlines Logo
2:39 pm - 4:04 am
MEM
-
PTY
13h 25m
2 stops
United Airlines Logo
10:00 am - 7:54 pm
PTY
-
MEM
9h 54m
1 stop
$505United Airlines
Sat, Aug 1 - Thu, Aug 6
United Airlines Logo
9:00 am - 6:37 pm
MEM
-
PTY
9h 37m
1 stop
United Airlines Logo
9:45 am - 9:54 pm
PTY
-
MEM
12h 09m
1 stop
$507United Airlines
Tue, May 12 - Tue, May 19
American Airlines Logo
12:25 pm - 12:46 pm
MEM
-
PTY
24h 21m
2 stops
American Airlines Logo
1:49 pm - 8:18 am
PTY
-
MEM
18h 29m
2 stops
$545American Airlines
Fri, May 8 - Fri, May 15
Delta Logo
5:15 am - 1:02 pm
MEM
-
PTY
7h 47m
1 stop
Delta Logo
2:27 pm - 10:13 pm
PTY
-
MEM
7h 46m
1 stop
$547Delta
Mon, Apr 20 - Mon, Apr 27
American Airlines Logo
6:09 pm - 12:46 pm
GPT
-
PTY
18h 37m
2 stops
American Airlines Logo
1:49 pm - 10:52 am
PTY
-
GPT
21h 03m
2 stops
$551American Airlines
Thu, May 14 - Wed, May 20
Delta Logo
6:32 am - 12:50 pm
GPT
-
PTY
6h 18m
1 stop
Delta Logo
2:15 pm - 9:51 pm
PTY
-
GPT
7h 36m
1 stop
$567Delta
Thu, May 14 - Wed, May 20
LATAM Airlines Logo
3:00 pm - 1:05 pm
GPT
-
PTY
22h 05m
1 stop
LATAM Airlines Logo
2:28 pm - 9:35 am
PTY
-
GPT
19h 07m
1 stop
$675LATAM Airlines
Sat, Aug 8 - Sun, Aug 30

Delta flights from Mississippi to Panama

Our best Delta deals on Mississippi to Panama flight tickets
Delta
Apr 20
MEM5:15 amMemphis
7h 47m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 27
PTY2:27 pmPanama City Tocumen Intl
7h 46m
1 stop
MEM10:13 pmMemphis
$547
Delta
May 14
GPT6:32 amGulfport Biloxi Regional
6h 18m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 20
PTY2:15 pmPanama City Tocumen Intl
7h 36m
1 stop
GPT9:51 pmGulfport Biloxi Regional
$567
Delta
May 8
BTR6:03 amBaton Rouge Ryan
6h 47m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 13
PTY2:15 pmPanama City Tocumen Intl
7h 45m
1 stop
BTR10:00 pmBaton Rouge Ryan
$693

American Airlines flights from Mississippi to Panama

Our best American Airlines deals on Mississippi to Panama flight tickets
American Airlines
May 8
MEM12:25 pmMemphis
24h 21m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 15
PTY1:49 pmPanama City Tocumen Intl
18h 29m
2 stops
MEM8:18 amMemphis
$545
American Airlines
May 14
GPT6:09 pmGulfport Biloxi Regional
18h 37m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 20
PTY1:49 pmPanama City Tocumen Intl
21h 03m
2 stops
GPT10:52 amGulfport Biloxi Regional
$551
American Airlines
Apr 10
MEM7:01 pmMemphis
17h 45m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 24
PTY1:49 pmPanama City Tocumen Intl
22h 39m
2 stops
MEM12:28 pmMemphis
$555

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Mississippi to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 7/28

11:46 am-6:37 pm

1 stop6h 51m

Panama City Tocumen Intl

Thu 7/30

7:55 am-6:12 pm

1 stop10h 17m

$467

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 7/28

4:08 pm-4:04 am

1 stop11h 56m

Panama City Tocumen Intl

Thu 7/30

3:30 pm-11:05 am

2 stops19h 35m

$471

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/1

7:00 am-6:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Thu 8/6

7:55 am-10:06 pm

1 stop14h 11m

$501

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/1

2:39 pm-4:04 am

2 stops13h 25m

Panama City Tocumen Intl

Thu 8/6

10:00 am-7:54 pm

1 stop9h 54m

$505

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 5/12

9:00 am-6:37 pm

1 stop9h 37m

Panama City Tocumen Intl

Tue 5/19

9:45 am-9:54 pm

1 stop12h 09m

$507

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 5/8

12:25 pm-12:46 pm

2 stops24h 21m

Panama City Tocumen Intl

Fri 5/15

1:49 pm-8:18 am

2 stops18h 29m

$545

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 4/20

5:15 am-1:02 pm

1 stop7h 47m

Panama City Tocumen Intl

Mon 4/27

2:27 pm-10:13 pm

1 stop7h 46m

$547

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 5/14

6:09 pm-12:46 pm

2 stops18h 37m

Panama City Tocumen Intl

Wed 5/20

1:49 pm-10:52 am

2 stops21h 03m

$551
Quickest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 5/14

6:32 am-12:50 pm

1 stop6h 18m

Panama City Tocumen Intl

Wed 5/20

2:15 pm-9:51 pm

1 stop7h 36m

$567

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 8/8

3:00 pm-1:05 pm

1 stop22h 05m

Panama City Tocumen Intl

Sun 8/30

2:28 pm-9:35 am

1 stop19h 07m

$675

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Mississippi to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Mississippi to Panama flights?

You could potentially save up to 53% on your flight if you consider stops on a Mississippi to Panama flight.

Cheap Mississippi to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama

Fastest flight time

6h 18m

Direct flights

None
The fastest flight from Mississippi to Panama takes 6h 18m
There are no direct flights from Mississippi to Panama. There are no popular flight routes from Mississippi to Panama.
  • When did momondo last update prices for flights from Mississippi to Panama?

    Prices for flights from Mississippi to Panama were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama?

  • How old do you have to be to fly from Mississippi to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama

Compare and see reviews for airlines that fly from Mississippi to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $462Free CancellationRating
7.4
9,499 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mississippi to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Mississippi to Panama with flexible booking policies on momondo?

Flights from Mississippi to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mississippi to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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1 adult
Mon 4/27
Mon 5/4

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