Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Mississippi to Panama from $249

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Panama departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Mississippi to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:41 am - 12:46 pm
MEM
-
PTY
7h 05m
1 stop
American Airlines Logo
1:49 pm - 12:44 pm
PTY
-
MEM
22h 55m
2 stops
$451American Airlines
Tue, Apr 21 - Fri, Apr 24
American Airlines Logo
5:45 am - 12:40 pm
MEM
-
PTY
6h 55m
1 stop
American Airlines Logo
3:51 pm - 11:52 pm
PTY
-
MEM
8h 01m
1 stop
$458American Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
1:17 pm - 12:46 pm
MEM
-
PTY
23h 29m
2 stops
American Airlines Logo
1:49 pm - 12:44 pm
PTY
-
MEM
22h 55m
2 stops
$459American Airlines
Tue, Apr 21 - Fri, Apr 24
American Airlines Logo
6:22 pm - 12:40 pm
MEM
-
PTY
18h 18m
2 stops
American Airlines Logo
3:51 pm - 8:56 am
PTY
-
MEM
17h 05m
2 stops
$491American Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
7:00 am - 4:07 pm
MOB
-
PTY
9h 07m
1 stop
United Airlines Logo
7:55 am - 9:57 pm
PTY
-
MOB
14h 02m
1 stop
$497United Airlines
Tue, Mar 10 - Tue, Mar 17
United Airlines Logo
4:55 pm - 4:12 pm
MOB
-
PTY
23h 17m
1 stop
United Airlines Logo
10:00 am - 9:59 pm
PTY
-
MOB
11h 59m
1 stop
$505United Airlines
Fri, Apr 24 - Sun, May 3
American Airlines Logo
6:33 pm - 12:46 pm
MOB
-
PTY
18h 13m
2 stops
American Airlines Logo
1:49 pm - 10:06 am
PTY
-
MOB
20h 17m
2 stops
$506American Airlines
Fri, Apr 24 - Sun, May 3
Copa Airlines Logo
7:05 am - 7:38 pm
GPT
-
PTY
11h 33m
1 stop
Copa Airlines Logo
3:41 pm - 4:06 pm
PTY
-
GPT
24h 25m
1 stop
$555Copa Airlines
Tue, Mar 3 - Fri, Mar 20
Copa Airlines Logo
7:00 am - 4:12 pm
MEM
-
PTY
9h 12m
1 stop
Copa Airlines Logo
9:45 am - 11:30 pm
PTY
-
MEM
13h 45m
1 stop
$561Copa Airlines
Sat, May 23 - Sat, May 30
Multiple Airlines Logo
6:18 am - 1:50 pm
BTR
-
PTY
6h 32m
1 stop
Multiple Airlines Logo
9:11 am - 9:08 pm
PTY
-
BTR
11h 57m
2 stops
$4,056Multiple Airlines
Fri, Mar 6 - Sun, Mar 8

American Airlines flights from Mississippi to Panama

Our best American Airlines deals on Mississippi to Panama flight tickets
American Airlines
Apr 21
MEM5:41 amMemphis
7h 05m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 24
PTY1:49 pmPanama City Tocumen Intl
22h 55m
2 stops
MEM12:44 pmMemphis
$451
American Airlines
Mar 24
MEM5:45 amMemphis
6h 55m
1 stop
PTY12:40 pmPanama City Tocumen Intl
Mar 31
PTY3:51 pmPanama City Tocumen Intl
8h 01m
1 stop
MEM11:52 pmMemphis
$458
American Airlines
Apr 21
MEM1:17 pmMemphis
23h 29m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 24
PTY1:49 pmPanama City Tocumen Intl
22h 55m
2 stops
MEM12:44 pmMemphis
$459

United Airlines flights from Mississippi to Panama

Our best United Airlines deals on Mississippi to Panama flight tickets
United Airlines
Mar 10
MOB7:00 amMobile
9h 07m
1 stop
PTY4:07 pmPanama City Tocumen Intl
Mar 17
PTY7:55 amPanama City Tocumen Intl
14h 02m
1 stop
MOB9:57 pmMobile
$497
United Airlines
Apr 24
MOB11:15 amMobile
28h 57m
1 stop
PTY4:12 pmPanama City Tocumen Intl
May 3
PTY10:00 amPanama City Tocumen Intl
11h 59m
1 stop
MOB9:59 pmMobile
$505
United Airlines
Apr 1
MEM9:00 amMemphis
7h 12m
1 stop
PTY4:12 pmPanama City Tocumen Intl
Apr 6
PTY3:30 pmPanama City Tocumen Intl
17h 30m
1 stop
MEM9:00 amMemphis
$511

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Mississippi to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 4/21

5:41 am-12:46 pm

1 stop7h 05m

Panama City Tocumen Intl

Fri 4/24

1:49 pm-12:44 pm

2 stops22h 55m

$451

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 3/24

5:45 am-12:40 pm

1 stop6h 55m

Panama City Tocumen Intl

Tue 3/31

3:51 pm-11:52 pm

1 stop8h 01m

$458

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 4/21

1:17 pm-12:46 pm

2 stops23h 29m

Panama City Tocumen Intl

Fri 4/24

1:49 pm-12:44 pm

2 stops22h 55m

$459

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Tue 3/24

6:22 pm-12:40 pm

2 stops18h 18m

Panama City Tocumen Intl

Tue 3/31

3:51 pm-8:56 am

2 stops17h 05m

$491

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Tue 3/10

7:00 am-4:07 pm

1 stop9h 07m

Panama City Tocumen Intl

Tue 3/17

7:55 am-9:57 pm

1 stop14h 02m

$497

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Fri 4/24

4:55 pm-4:12 pm

1 stop23h 17m

Panama City Tocumen Intl

Sun 5/3

10:00 am-9:59 pm

1 stop11h 59m

$505

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Fri 4/24

6:33 pm-12:46 pm

2 stops18h 13m

Panama City Tocumen Intl

Sun 5/3

1:49 pm-10:06 am

2 stops20h 17m

$506

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 3/3

7:05 am-7:38 pm

1 stop11h 33m

Panama City Tocumen Intl

Fri 3/20

3:41 pm-4:06 pm

1 stop24h 25m

$555

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 5/23

7:00 am-4:12 pm

1 stop9h 12m

Panama City Tocumen Intl

Sat 5/30

9:45 am-11:30 pm

1 stop13h 45m

$561

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Fri 3/6

6:18 am-1:50 pm

1 stop6h 32m

Panama City Tocumen Intl

Sun 3/8

9:11 am-9:08 pm

2 stops11h 57m

$4,056

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to Panama from

How to get the cheapest flight ticket from Mississippi to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Panama?

United Airlines, Copa Airlines, and GOL are the most popular carriers operating from Mississippi to Panama

Cheap Mississippi to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Panama

Fastest flight time

6h 43m

Direct flights

None
The fastest flight from Mississippi to Panama takes 6h 43m
There are no direct flights from Mississippi to Panama. There are no popular flight routes from Mississippi to Panama.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Panama?

    Prices for flights from Mississippi to Panama were last updated today.

  • How many operators does momondo search for flights from Mississippi to Panama?

  • How old do you have to be to fly from Mississippi to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Panama

Compare and see reviews for airlines that fly from Mississippi to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $445Free CancellationRating
7.4
9,262 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mississippi to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Mississippi to Panama with flexible booking policies on momondo?

Flights from Mississippi to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mississippi to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Mississippi. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mississippi to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 3/11
Wed 3/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo
Flights to Panama Cityfrom $278
Flights to Bocas del Torofrom $708
Flights to Davidfrom $380
Flights to Changuinola