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Cheap flights from Chicago Midway Airport to Santiago from $348

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Santiago departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
12:47 pm - 7:40 amMDW-SCL
15h 53m1 stop
LATAM Airlines Logo
11:25 pm - 11:55 amSCL-MDW
15h 30m2 stops
$684LATAM Airlines
Find Deal
Tue, Nov 25 - Tue, Dec 9
LATAM Airlines Logo
12:47 pm - 7:40 amMDW-SCL
15h 53m1 stop
LATAM Airlines Logo
11:10 pm - 9:52 amSCL-MDW
13h 42m1 stop
$690LATAM Airlines
Find Deal
Thu, Nov 13 - Wed, Nov 19
LATAM Airlines Logo
10:47 am - 7:40 amMDW-SCL
17h 53m1 stop
LATAM Airlines Logo
11:10 pm - 9:54 amSCL-MDW
13h 44m1 stop
$695LATAM Airlines
Find Deal
Wed, Nov 19 - Mon, Dec 1
LATAM Airlines Logo
6:00 am - 7:00 amMDW-SCL
22h 00m1 stop
LATAM Airlines Logo
11:15 pm - 9:56 amSCL-MDW
13h 41m1 stop
$704LATAM Airlines
Find Deal
Mon, Feb 2 - Tue, Feb 17
LATAM Airlines Logo
4:30 pm - 2:05 pmMDW-SCL
18h 35m2 stops
LATAM Airlines Logo
11:10 pm - 12:01 pmSCL-MDW
15h 51m1 stop
$717LATAM Airlines
Find Deal
Sat, Jan 24 - Thu, Feb 5
LATAM Airlines Logo
10:46 am - 5:50 amMDW-SCL
16h 04m2 stops
LATAM Airlines Logo
11:25 pm - 12:01 pmSCL-MDW
15h 36m2 stops
$723LATAM Airlines
Find Deal
Mon, Feb 2 - Tue, Feb 17
Delta Logo
11:21 am - 7:40 amMDW-SCL
17h 19m1 stop
Delta Logo
11:10 pm - 9:58 amSCL-MDW
13h 48m1 stop
$724Delta
Find Deal
Mon, Jan 12 - Mon, Jan 26
Delta Logo
1:28 pm - 7:40 amMDW-SCL
15h 12m2 stops
Delta Logo
8:15 am - 10:26 pmSCL-MDW
17h 11m2 stops
$729Delta
Find Deal
Tue, Jan 27 - Tue, Feb 10
Multiple Airlines Logo
5:57 pm - 6:35 amMDW-SCL
33h 38m2 stops
Multiple Airlines Logo
10:35 am - 10:30 pmSCL-MDW
14h 55m1 stop
$757Multiple Airlines
Find Deal
Wed, Nov 26 - Sat, Dec 6
Delta Logo
10:35 am - 6:35 amMDW-SCL
18h 00m2 stops
Delta Logo
11:15 pm - 12:01 pmSCL-MDW
14h 46m1 stop
$764Delta
Find Deal
Mon, Mar 9 - Wed, Mar 18

LATAM Airlines flights from Chicago Midway Airport to Santiago

Our best LATAM Airlines deals on Chicago Midway Airport to Santiago flight tickets
LATAM Airlines
Nov 25
MDW12:47 pmChicago Midway
15h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 9
SCL11:25 pmSantiago Arturo Merino Benitez
15h 30m
2 stops
MDW11:55 amChicago Midway
$684
Find similar
LATAM Airlines
Nov 13
MDW12:47 pmChicago Midway
15h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 19
SCL11:10 pmSantiago Arturo Merino Benitez
13h 42m
1 stop
MDW9:52 amChicago Midway
$690
Find similar
LATAM Airlines
Nov 19
MDW10:47 amChicago Midway
17h 53m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 1
SCL11:10 pmSantiago Arturo Merino Benitez
13h 44m
1 stop
MDW9:54 amChicago Midway
$695
Find similar

Delta flights from Chicago Midway Airport to Santiago

Our best Delta deals on Chicago Midway Airport to Santiago flight tickets
Delta
Jan 12
MDW11:21 amChicago Midway
17h 19m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Jan 26
SCL11:10 pmSantiago Arturo Merino Benitez
13h 48m
1 stop
MDW9:58 amChicago Midway
$724
Find similar
Delta
Jan 27
MDW1:28 pmChicago Midway
15h 12m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Feb 10
SCL8:15 amSantiago Arturo Merino Benitez
17h 11m
2 stops
MDW10:26 pmChicago Midway
$729
Find similar
Delta
Mar 9
MDW10:35 amChicago Midway
18h 00m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Mar 18
SCL11:15 pmSantiago Arturo Merino Benitez
14h 46m
1 stop
MDW12:01 pmChicago Midway
$764
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 11/25

12:47 pm-7:40 am

1 stop15h 53m

Santiago Arturo Merino Benitez

Tue 12/9

11:25 pm-11:55 am

2 stops15h 30m

$684

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 11/13

12:47 pm-7:40 am

1 stop15h 53m

Santiago Arturo Merino Benitez

Wed 11/19

11:10 pm-9:52 am

1 stop13h 42m

$690

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Wed 11/19

10:47 am-7:40 am

1 stop17h 53m

Santiago Arturo Merino Benitez

Mon 12/1

11:10 pm-9:54 am

1 stop13h 44m

$695

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 2/2

6:00 am-7:00 am

1 stop22h 00m

Santiago Arturo Merino Benitez

Tue 2/17

11:15 pm-9:56 am

1 stop13h 41m

$704

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sat 1/24

4:30 pm-2:05 pm

2 stops18h 35m

Santiago Arturo Merino Benitez

Thu 2/5

11:10 pm-12:01 pm

1 stop15h 51m

$717

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 2/2

10:46 am-5:50 am

2 stops16h 04m

Santiago Arturo Merino Benitez

Tue 2/17

11:25 pm-12:01 pm

2 stops15h 36m

$723

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 1/12

11:21 am-7:40 am

1 stop17h 19m

Santiago Arturo Merino Benitez

Mon 1/26

11:10 pm-9:58 am

1 stop13h 48m

$724

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 1/27

1:28 pm-7:40 am

2 stops15h 12m

Santiago Arturo Merino Benitez

Tue 2/10

8:15 am-10:26 pm

2 stops17h 11m

$729

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Wed 11/26

5:57 pm-6:35 am

2 stops33h 38m

Santiago Arturo Merino Benitez

Sat 12/6

10:35 am-10:30 pm

1 stop14h 55m

$757

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 3/9

10:35 am-6:35 am

2 stops18h 00m

Santiago Arturo Merino Benitez

Wed 3/18

11:15 pm-12:01 pm

1 stop14h 46m

$764

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago Midway Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago Midway Airport to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

Can stopping save me money on Chicago Midway Airport to Santiago flights?

You could potentially save up to 9% on your flight if you consider stops on a Chicago Midway Airport to Santiago flight.

When to book flights from Chicago Midway Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santiago (MDW to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santiago

Direct flights

None
There are no direct flights from Chicago Midway Airport to Santiago. There are no popular flight routes from Chicago Midway Airport to Santiago.
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  • How far is Chicago Midway to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Chicago Midway to Santiago Arturo Merino Benitez is 5306.6 mi. 12h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How old do you have to be to fly from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Chicago.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Chicago with this policy.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search for Chicago to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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