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Cheap flights from Chicago Midway Airport to Santiago from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Santiago departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:46 am - 6:00 am
MDW
-
SCL
18h 14m
2 stops
Delta Logo
8:40 pm - 4:17 pm
SCL
-
MDW
20h 37m
1 stop
$573Delta
Mon, May 18 - Thu, May 21
Delta Logo
9:35 am - 7:40 am
MDW
-
SCL
20h 05m
2 stops
Delta Logo
10:25 pm - 5:54 pm
SCL
-
MDW
21h 29m
2 stops
$578Delta
Mon, Mar 9 - Thu, Mar 19
LATAM Airlines Logo
6:00 am - 5:55 am
MDW
-
SCL
21h 55m
2 stops
LATAM Airlines Logo
10:40 pm - 10:31 pm
SCL
-
MDW
25h 51m
2 stops
$601LATAM Airlines
Sun, Mar 8 - Wed, Mar 11
LATAM Airlines Logo
6:00 am - 7:40 am
MDW
-
SCL
23h 40m
1 stop
LATAM Airlines Logo
10:25 pm - 9:56 am
SCL
-
MDW
13h 31m
1 stop
$606LATAM Airlines
Mon, Mar 9 - Thu, Mar 19
LATAM Airlines Logo
6:00 am - 7:15 am
MDW
-
SCL
24h 15m
1 stop
LATAM Airlines Logo
8:40 pm - 9:09 pm
SCL
-
MDW
25h 29m
1 stop
$617LATAM Airlines
Sun, Apr 26 - Mon, May 18
LATAM Airlines Logo
6:00 am - 6:55 am
MDW
-
SCL
21h 55m
2 stops
LATAM Airlines Logo
10:30 am - 9:56 am
SCL
-
MDW
25h 26m
2 stops
$624LATAM Airlines
Mon, Mar 2 - Wed, Apr 1
LATAM Airlines Logo
5:21 pm - 1:05 pm
MDW
-
SCL
18h 44m
2 stops
LATAM Airlines Logo
11:05 pm - 10:28 pm
SCL
-
MDW
24h 23m
2 stops
$649LATAM Airlines
Sun, Apr 19 - Fri, Apr 24
LATAM Airlines Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m
1 stop
LATAM Airlines Logo
4:50 pm - 12:02 pm
SCL
-
MDW
20h 12m
2 stops
$656LATAM Airlines
Thu, Mar 26 - Tue, Apr 7
LATAM Airlines Logo
10:45 am - 7:40 am
MDW
-
SCL
18h 55m
1 stop
LATAM Airlines Logo
11:00 pm - 5:22 pm
SCL
-
MDW
19h 22m
2 stops
$661LATAM Airlines
Thu, Mar 26 - Mon, Apr 6
LATAM Airlines Logo
6:00 am - 7:40 am
MDW
-
SCL
23h 40m
1 stop
LATAM Airlines Logo
12:20 am - 5:22 pm
SCL
-
MDW
19h 02m
2 stops
$676LATAM Airlines
Sun, Mar 22 - Mon, Mar 23

LATAM Airlines flights from Chicago Midway Airport to Santiago

Our best LATAM Airlines deals on Chicago Midway Airport to Santiago flight tickets
LATAM Airlines
Mar 8
MDW6:00 amChicago Midway
21h 55m
2 stops
SCL5:55 amSantiago Arturo Merino Benitez
Mar 11
SCL10:40 pmSantiago Arturo Merino Benitez
25h 51m
2 stops
MDW10:31 pmChicago Midway
$601
LATAM Airlines
Mar 9
MDW6:00 amChicago Midway
23h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 19
SCL10:25 pmSantiago Arturo Merino Benitez
13h 31m
1 stop
MDW9:56 amChicago Midway
$606
LATAM Airlines
Apr 26
MDW6:00 amChicago Midway
24h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
May 18
SCL8:40 pmSantiago Arturo Merino Benitez
25h 29m
1 stop
MDW9:09 pmChicago Midway
$617

Delta flights from Chicago Midway Airport to Santiago

Our best Delta deals on Chicago Midway Airport to Santiago flight tickets
Delta
May 18
MDW10:46 amChicago Midway
18h 14m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
May 21
SCL8:40 pmSantiago Arturo Merino Benitez
20h 37m
1 stop
MDW4:17 pmChicago Midway
$573
Delta
Mar 9
MDW9:35 amChicago Midway
20h 05m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Mar 19
SCL10:25 pmSantiago Arturo Merino Benitez
21h 29m
2 stops
MDW5:54 pmChicago Midway
$578
Delta
Mar 10
MDW9:35 amChicago Midway
20h 05m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Mar 17
SCL10:25 pmSantiago Arturo Merino Benitez
16h 04m
2 stops
MDW12:29 pmChicago Midway
$692

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 5/18

10:46 am-6:00 am

2 stops18h 14m

Santiago Arturo Merino Benitez

Thu 5/21

8:40 pm-4:17 pm

1 stop20h 37m

$573

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 3/9

9:35 am-7:40 am

2 stops20h 05m

Santiago Arturo Merino Benitez

Thu 3/19

10:25 pm-5:54 pm

2 stops21h 29m

$578

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 3/8

6:00 am-5:55 am

2 stops21h 55m

Santiago Arturo Merino Benitez

Wed 3/11

10:40 pm-10:31 pm

2 stops25h 51m

$601

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 3/9

6:00 am-7:40 am

1 stop23h 40m

Santiago Arturo Merino Benitez

Thu 3/19

10:25 pm-9:56 am

1 stop13h 31m

$606

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 4/26

6:00 am-7:15 am

1 stop24h 15m

Santiago Arturo Merino Benitez

Mon 5/18

8:40 pm-9:09 pm

1 stop25h 29m

$617

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 3/2

6:00 am-6:55 am

2 stops21h 55m

Santiago Arturo Merino Benitez

Wed 4/1

10:30 am-9:56 am

2 stops25h 26m

$624

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 4/19

5:21 pm-1:05 pm

2 stops18h 44m

Santiago Arturo Merino Benitez

Fri 4/24

11:05 pm-10:28 pm

2 stops24h 23m

$649

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 3/26

12:47 pm-7:40 am

1 stop16h 53m

Santiago Arturo Merino Benitez

Tue 4/7

4:50 pm-12:02 pm

2 stops20h 12m

$656

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 3/26

10:45 am-7:40 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Mon 4/6

11:00 pm-5:22 pm

2 stops19h 22m

$661

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 3/22

6:00 am-7:40 am

1 stop23h 40m

Santiago Arturo Merino Benitez

Mon 3/23

12:20 am-5:22 pm

2 stops19h 02m

$676

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago Midway Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Chicago Midway Airport to Santiago flights?

You could potentially save up to 9% on your flight if you consider stops on a Chicago Midway Airport to Santiago flight.

When to book flights from Chicago Midway Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Santiago (MDW to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Santiago

Fastest flight time

13h 01m

Direct flights

None
The fastest flight from Chicago Midway Airport to Santiago takes 13h 01m
There are no direct flights from Chicago Midway Airport to Santiago. There are no popular flight routes from Chicago Midway Airport to Santiago.
Search flight deals

  • How far is Chicago Midway to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Chicago Midway to Santiago Arturo Merino Benitez is 5306.6 mi. 13h 01m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How old do you have to be to fly from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago Midway Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Chicago.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Chicago with this policy.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search for Chicago to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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