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Cheap flights from Chicago Midway Airport to Panama City from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama City departing on 6/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
Delta Logo
2:15 pm - 8:43 am
PTY
-
MDW
18h 28m
2 stops
$742Delta
lun., may. 4 - jue., may. 14
Multiple Airlines Logo
11:33 am - 9:15 am
MDW
-
PTY
21h 42m
2 stops
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$747Multiple Airlines
vie., may. 1 - mar., may. 5
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
Delta Logo
2:15 pm - 10:00 am
PTY
-
MDW
19h 45m
1 stop
$749Delta
lun., may. 4 - mar., may. 12
Multiple Airlines Logo
12:24 pm - 8:34 pm
MDW
-
PTY
8h 10m
1 stop
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$750Multiple Airlines
mar., may. 5 - mar., may. 12
Delta Logo
1:22 pm - 12:50 pm
MDW
-
PTY
23h 28m
2 stops
Delta Logo
2:15 pm - 8:43 am
PTY
-
MDW
18h 28m
2 stops
$762Delta
mar., may. 19 - mar., jun. 2
Multiple Airlines Logo
12:04 pm - 8:34 pm
MDW
-
PTY
8h 30m
1 stop
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$765Multiple Airlines
lun., jun. 1 - sáb., jun. 6
Multiple Airlines Logo
12:27 pm - 8:30 am
MDW
-
PTY
20h 03m
2 stops
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$776Multiple Airlines
jue., may. 28 - dom., may. 31
Multiple Airlines Logo
12:04 pm - 8:34 pm
MDW
-
PTY
8h 30m
1 stop
Multiple Airlines Logo
9:33 pm - 10:02 pm
PTY
-
MDW
24h 29m
2 stops
$782Multiple Airlines
lun., may. 11 - lun., may. 18
Multiple Airlines Logo
11:59 am - 8:34 pm
MDW
-
PTY
8h 35m
1 stop
Multiple Airlines Logo
9:33 pm - 2:07 pm
PTY
-
MDW
16h 34m
2 stops
$785Multiple Airlines
sáb., jun. 6 - sáb., jun. 13
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$788Multiple Airlines
jue., may. 7 - jue., may. 14

Delta flights from Chicago Midway Airport to Panama City

Our best Delta deals on Chicago Midway Airport to Panama City flight tickets
Delta
May 4
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 14
PTY2:15 pmPanama City Tocumen Intl
18h 28m
2 stops
MDW8:43 amChicago Midway
$742
Delta
May 4
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 12
PTY2:15 pmPanama City Tocumen Intl
19h 45m
1 stop
MDW10:00 amChicago Midway
$749
Delta
May 19
MDW1:22 pmChicago Midway
23h 28m
2 stops
PTY12:50 pmPanama City Tocumen Intl
Jun 2
PTY2:15 pmPanama City Tocumen Intl
18h 28m
2 stops
MDW8:43 amChicago Midway
$762

LATAM Airlines flights from Chicago Midway Airport to Panama City

Our best LATAM Airlines deals on Chicago Midway Airport to Panama City flight tickets
LATAM Airlines
Jul 31
MDW6:05 amChicago Midway
7h 00m
1 stop
PTY1:05 pmPanama City Tocumen Intl
Aug 9
PTY2:24 pmPanama City Tocumen Intl
26h 03m
1 stop
MDW4:27 pmChicago Midway
$868
LATAM Airlines
Jun 6
MDW10:45 amChicago Midway
26h 24m
1 stop
PTY1:09 pmPanama City Tocumen Intl
Jun 13
PTY2:27 pmPanama City Tocumen Intl
7h 50m
1 stop
MDW10:17 pmChicago Midway
$944
LATAM Airlines
Apr 13
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 15
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$959

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated abril 10, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 5/4

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

jue. 5/14

2:15 pm-8:43 am

2 stops18h 28m

$742

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

vie. 5/1

11:33 am-9:15 am

2 stops21h 42m

Panama City Tocumen Intl

mar. 5/5

10:26 am-10:02 pm

1 stop11h 36m

$747

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 5/4

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

mar. 5/12

2:15 pm-10:00 am

1 stop19h 45m

$749
Quickest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 5/5

12:24 pm-8:34 pm

1 stop8h 10m

Panama City Tocumen Intl

mar. 5/12

10:26 am-10:02 pm

1 stop11h 36m

$750

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 5/19

1:22 pm-12:50 pm

2 stops23h 28m

Panama City Tocumen Intl

mar. 6/2

2:15 pm-8:43 am

2 stops18h 28m

$762

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 6/1

12:04 pm-8:34 pm

1 stop8h 30m

Panama City Tocumen Intl

sáb. 6/6

10:26 am-10:02 pm

1 stop11h 36m

$765

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

jue. 5/28

12:27 pm-8:30 am

2 stops20h 03m

Panama City Tocumen Intl

dom. 5/31

10:26 am-10:02 pm

1 stop11h 36m

$776

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 5/11

12:04 pm-8:34 pm

1 stop8h 30m

Panama City Tocumen Intl

lun. 5/18

9:33 pm-10:02 pm

2 stops24h 29m

$782

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

sáb. 6/6

11:59 am-8:34 pm

1 stop8h 35m

Panama City Tocumen Intl

sáb. 6/13

9:33 pm-2:07 pm

2 stops16h 34m

$785

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

jue. 5/7

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

jue. 5/14

10:26 am-10:02 pm

1 stop11h 36m

$788

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $528. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $583. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago Midway Airport to Panama City during this time can be as low as $486. Try not to purchase tickets in the morning because they tend to be around $577. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Panama City (MDW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama City

Fastest flight time

6h 54m

Direct flights

None
The fastest flight from Chicago Midway Airport to Panama City takes 6h 54m
There are no direct flights from Chicago Midway Airport to Panama City. There are no popular flight routes from Chicago Midway Airport to Panama City.
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Panama City

  • How far is Chicago Midway to Panama City Tocumen Intl by plane?

    Chicago Midway and Panama City Tocumen Intl are 2319.5 mi apart from one another. By plane, this route typically takes 6h 54m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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