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Cheap flights from Chicago Midway Airport to Panama City from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama City departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:33 am - 7:28 pm
MDW
-
PTY
7h 55m
1 stop
Multiple Airlines Logo
7:24 am - 3:57 pm
PTY
-
MDW
8h 33m
1 stop
$553Multiple Airlines
Fri, May 1 - Fri, May 8
Multiple Airlines Logo
6:30 am - 1:55 am
MDW
-
PTY
19h 25m
2 stops
Multiple Airlines Logo
5:30 am - 10:14 pm
PTY
-
MDW
16h 44m
3 stops
$559Multiple Airlines
Sat, Apr 11 - Sat, Apr 18
Multiple Airlines Logo
11:59 am - 8:34 pm
MDW
-
PTY
8h 35m
1 stop
Multiple Airlines Logo
10:26 am - 10:02 pm
PTY
-
MDW
11h 36m
1 stop
$584Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
9:14 am - 5:53 pm
MDW
-
PTY
8h 39m
1 stop
Multiple Airlines Logo
7:24 am - 4:13 pm
PTY
-
MDW
8h 49m
1 stop
$624Multiple Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
11:33 am - 7:28 pm
MDW
-
PTY
7h 55m
1 stop
Multiple Airlines Logo
7:24 am - 3:57 pm
PTY
-
MDW
8h 33m
1 stop
$626Multiple Airlines
Fri, May 1 - Fri, May 8
Multiple Airlines Logo
12:27 pm - 8:34 pm
MDW
-
PTY
8h 07m
1 stop
Multiple Airlines Logo
9:33 pm - 2:12 pm
PTY
-
MDW
16h 39m
2 stops
$659Multiple Airlines
Tue, May 12 - Tue, May 19
Multiple Airlines Logo
7:30 am - 12:35 am
MDW
-
PTY
17h 05m
2 stops
Multiple Airlines Logo
10:26 am - 6:37 pm
PTY
-
MDW
8h 11m
1 stop
$682Multiple Airlines
Wed, Apr 15 - Sat, Apr 18
Multiple Airlines Logo
7:30 am - 12:35 am
MDW
-
PTY
17h 05m
2 stops
Multiple Airlines Logo
10:26 am - 6:37 pm
PTY
-
MDW
8h 11m
1 stop
$687Multiple Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
6:30 am - 12:35 am
MDW
-
PTY
18h 05m
2 stops
Multiple Airlines Logo
10:26 am - 7:31 pm
PTY
-
MDW
9h 05m
1 stop
$693Multiple Airlines
Fri, Apr 10 - Sun, May 3
Multiple Airlines Logo
7:30 am - 12:35 am
MDW
-
PTY
17h 05m
2 stops
Multiple Airlines Logo
10:26 am - 10:19 pm
PTY
-
MDW
11h 53m
1 stop
$698Multiple Airlines
Wed, Apr 15 - Sun, Apr 19

LATAM Airlines flights from Chicago Midway Airport to Panama City

Our best LATAM Airlines deals on Chicago Midway Airport to Panama City flight tickets
LATAM Airlines
Sep 6
MDW6:00 amChicago Midway
7h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
Sep 19
PTY2:21 pmPanama City Tocumen Intl
21h 33m
1 stop
MDW11:54 amChicago Midway
$866
LATAM Airlines
May 22
MDW10:59 amChicago Midway
25h 51m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 25
PTY2:15 pmPanama City Tocumen Intl
19h 45m
1 stop
MDW10:00 amChicago Midway
$878
LATAM Airlines
Jul 18
MDW4:22 pmChicago Midway
20h 43m
1 stop
PTY1:05 pmPanama City Tocumen Intl
Jul 24
PTY2:24 pmPanama City Tocumen Intl
7h 51m
1 stop
MDW10:15 pmChicago Midway
$900

Delta flights from Chicago Midway Airport to Panama City

Our best Delta deals on Chicago Midway Airport to Panama City flight tickets
Delta
May 14
MDW5:10 pmChicago Midway
19h 40m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 20
PTY2:15 pmPanama City Tocumen Intl
18h 28m
2 stops
MDW8:43 amChicago Midway
$777
Delta
Jun 20
MDW6:05 amChicago Midway
6h 54m
1 stop
PTY12:59 pmPanama City Tocumen Intl
Jul 3
PTY2:24 pmPanama City Tocumen Intl
7h 53m
1 stop
MDW10:17 pmChicago Midway
$785
Delta
Apr 26
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 3
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$895

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 5/1

11:33 am-7:28 pm

1 stop7h 55m

Panama City Tocumen Intl

Fri 5/8

7:24 am-3:57 pm

1 stop8h 33m

$553

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/11

6:30 am-1:55 am

2 stops19h 25m

Panama City Tocumen Intl

Sat 4/18

5:30 am-10:14 pm

3 stops16h 44m

$559

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 5/9

11:59 am-8:34 pm

1 stop8h 35m

Panama City Tocumen Intl

Sat 5/16

10:26 am-10:02 pm

1 stop11h 36m

$584

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/25

9:14 am-5:53 pm

1 stop8h 39m

Panama City Tocumen Intl

Sat 5/2

7:24 am-4:13 pm

1 stop8h 49m

$624

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 5/1

11:33 am-7:28 pm

1 stop7h 55m

Panama City Tocumen Intl

Fri 5/8

7:24 am-3:57 pm

1 stop8h 33m

$626

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 5/12

12:27 pm-8:34 pm

1 stop8h 07m

Panama City Tocumen Intl

Tue 5/19

9:33 pm-2:12 pm

2 stops16h 39m

$659

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 4/15

7:30 am-12:35 am

2 stops17h 05m

Panama City Tocumen Intl

Sat 4/18

10:26 am-6:37 pm

1 stop8h 11m

$682

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/25

7:30 am-12:35 am

2 stops17h 05m

Panama City Tocumen Intl

Sat 5/2

10:26 am-6:37 pm

1 stop8h 11m

$687

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 4/10

6:30 am-12:35 am

2 stops18h 05m

Panama City Tocumen Intl

Sun 5/3

10:26 am-7:31 pm

1 stop9h 05m

$693

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 4/15

7:30 am-12:35 am

2 stops17h 05m

Panama City Tocumen Intl

Sun 4/19

10:26 am-10:19 pm

1 stop11h 53m

$698

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $520. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $581. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago Midway Airport to Panama City during this time can be as low as $486. Try not to purchase tickets in the morning because they tend to be around $576. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Panama City (MDW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama City

Fastest flight time

7h 02m

Direct flights

None
The fastest flight from Chicago Midway Airport to Panama City takes 7h 02m
There are no direct flights from Chicago Midway Airport to Panama City. There are no popular flight routes from Chicago Midway Airport to Panama City.
Search flight deals

  • How far is Chicago Midway to Panama City Tocumen Intl by plane?

    Chicago Midway and Panama City Tocumen Intl are 2319.5 mi apart from one another. By plane, this route typically takes 7h 02m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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