Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Chicago Midway Airport to Panama City from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama City departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago Midway Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:27 pm - 8:34 pm
MDW
-
PTY
8h 07m
1 stop
Multiple Airlines Logo
10:25 am - 10:11 pm
PTY
-
MDW
11h 46m
2 stops
$662Multiple Airlines
Tue, Jun 2 - Tue, Jun 9
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
10:25 am - 10:02 pm
PTY
-
MDW
11h 37m
2 stops
$699Multiple Airlines
Sat, May 30 - Wed, Jun 3
Multiple Airlines Logo
12:04 pm - 8:34 pm
MDW
-
PTY
8h 30m
1 stop
Multiple Airlines Logo
9:33 pm - 11:12 am
PTY
-
MDW
13h 39m
2 stops
$704Multiple Airlines
Fri, Jun 5 - Mon, Jun 8
Delta Logo
6:00 am - 1:13 pm
MDW
-
PTY
7h 13m
1 stop
Delta Logo
2:28 pm - 9:50 am
PTY
-
MDW
19h 22m
1 stop
$712Delta
Tue, Aug 11 - Mon, Aug 17
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
9:33 pm - 10:02 pm
PTY
-
MDW
24h 29m
2 stops
$723Multiple Airlines
Sat, May 9 - Tue, May 12
Delta Logo
6:00 am - 1:13 pm
MDW
-
PTY
7h 13m
1 stop
Delta Logo
2:28 pm - 9:50 am
PTY
-
MDW
19h 22m
1 stop
$741Delta
Tue, Aug 11 - Sun, Aug 16
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
6:34 pm - 2:12 pm
PTY
-
MDW
19h 38m
2 stops
$745Multiple Airlines
Wed, Jun 3 - Sun, Jun 7
Multiple Airlines Logo
12:27 pm - 8:34 pm
MDW
-
PTY
8h 07m
1 stop
Multiple Airlines Logo
9:33 pm - 10:02 pm
PTY
-
MDW
24h 29m
2 stops
$746Multiple Airlines
Tue, May 26 - Tue, Jun 2
Multiple Airlines Logo
12:27 pm - 8:34 pm
MDW
-
PTY
8h 07m
1 stop
Multiple Airlines Logo
9:33 pm - 2:12 pm
PTY
-
MDW
16h 39m
2 stops
$748Multiple Airlines
Tue, Jun 2 - Sun, Jun 7
Multiple Airlines Logo
11:59 am - 8:34 pm
MDW
-
PTY
8h 35m
1 stop
Multiple Airlines Logo
6:34 pm - 10:02 pm
PTY
-
MDW
27h 28m
2 stops
$749Multiple Airlines
Sat, May 23 - Tue, May 26

Delta flights from Chicago Midway Airport to Panama City

Our best Delta deals on Chicago Midway Airport to Panama City flight tickets
Delta
Aug 11
MDW6:00 amChicago Midway
7h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
Aug 17
PTY2:28 pmPanama City Tocumen Intl
19h 22m
1 stop
MDW9:50 amChicago Midway
$712
Delta
Aug 11
MDW6:00 amChicago Midway
7h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
Aug 16
PTY2:28 pmPanama City Tocumen Intl
19h 22m
1 stop
MDW9:50 amChicago Midway
$741
Delta
Jun 6
MDW6:36 pmChicago Midway
18h 33m
2 stops
PTY1:09 pmPanama City Tocumen Intl
Jun 10
PTY2:24 pmPanama City Tocumen Intl
7h 53m
1 stop
MDW10:17 pmChicago Midway
$762

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 6/2

12:27 pm-8:34 pm

1 stop8h 07m

Panama City Tocumen Intl

Tue 6/9

10:25 am-10:11 pm

2 stops11h 46m

$662

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 5/30

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Wed 6/3

10:25 am-10:02 pm

2 stops11h 37m

$699

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 6/5

12:04 pm-8:34 pm

1 stop8h 30m

Panama City Tocumen Intl

Mon 6/8

9:33 pm-11:12 am

2 stops13h 39m

$704

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 8/11

6:00 am-1:13 pm

1 stop7h 13m

Panama City Tocumen Intl

Mon 8/17

2:28 pm-9:50 am

1 stop19h 22m

$712

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 5/9

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Tue 5/12

9:33 pm-10:02 pm

2 stops24h 29m

$723

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 8/11

6:00 am-1:13 pm

1 stop7h 13m

Panama City Tocumen Intl

Sun 8/16

2:28 pm-9:50 am

1 stop19h 22m

$741

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 6/3

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Sun 6/7

6:34 pm-2:12 pm

2 stops19h 38m

$745

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 5/26

12:27 pm-8:34 pm

1 stop8h 07m

Panama City Tocumen Intl

Tue 6/2

9:33 pm-10:02 pm

2 stops24h 29m

$746

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 6/2

12:27 pm-8:34 pm

1 stop8h 07m

Panama City Tocumen Intl

Sun 6/7

9:33 pm-2:12 pm

2 stops16h 39m

$748

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 5/23

11:59 am-8:34 pm

1 stop8h 35m

Panama City Tocumen Intl

Tue 5/26

6:34 pm-10:02 pm

2 stops27h 28m

$749

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $529. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $587. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago Midway Airport to Panama City during this time can be as low as $466. Try not to purchase tickets in the morning because they tend to be around $578. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Panama City (MDW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama City

Fastest flight time

8h 07m

Direct flights

None
The fastest flight from Chicago Midway Airport to Panama City takes 8h 07m
There are no direct flights from Chicago Midway Airport to Panama City. There are no popular flight routes from Chicago Midway Airport to Panama City.
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Panama City

  • How far is Chicago Midway to Panama City Tocumen Intl by plane?

    Chicago Midway and Panama City Tocumen Intl are 2319.5 mi apart from one another. By plane, this route typically takes 8h 07m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 5/25
Mon 6/1
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama