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Cheap flights from Chicago Midway Airport to Panama City from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama City departing on 11/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Panama City

Cheap round-trip flights

Delta Logo
6:00 am - 2:12 pmMDW-PTY
7h 12m1 stop
Delta Logo
3:46 pm - 11:32 pmPTY-MDW
8h 46m1 stop
$465Delta
Find Deal
sáb., nov. 29 - mié., dic. 3
Delta Logo
9:30 am - 8:04 pmMDW-PTY
9h 34m2 stops
Delta Logo
8:05 am - 4:25 pmPTY-MDW
9h 20m1 stop
$470Delta
Find Deal
sáb., ene. 10 - sáb., ene. 17
Multiple Airlines Logo
7:50 am - 12:40 amMDW-PTY
16h 50m2 stops
Multiple Airlines Logo
9:33 pm - 9:22 pmPTY-MDW
24h 49m1 stop
$534Multiple Airlines
Find Deal
vie., oct. 31 - vie., nov. 7
Multiple Airlines Logo
7:50 am - 12:40 amMDW-PTY
16h 50m2 stops
Multiple Airlines Logo
9:11 am - 12:30 amPTY-MDW
16h 19m1 stop
$568Multiple Airlines
Find Deal
vie., oct. 31 - lun., nov. 10
Delta Logo
6:00 am - 12:55 pmMDW-PTY
6h 55m1 stop
Delta Logo
2:20 pm - 12:35 pmPTY-MDW
22h 15m2 stops
$582Delta
Find Deal
mar., mar. 10 - mié., mar. 11
Multiple Airlines Logo
6:20 am - 7:33 pmMDW-PTY
13h 13m1 stop
Multiple Airlines Logo
9:25 am - 10:03 pmPTY-MDW
13h 38m1 stop
$586Multiple Airlines
Find Deal
jue., oct. 30 - dom., nov. 2
Delta Logo
6:00 am - 12:55 pmMDW-PTY
6h 55m1 stop
Delta Logo
2:20 pm - 4:25 pmPTY-MDW
26h 05m1 stop
$587Delta
Find Deal
mar., mar. 10 - mié., mar. 11
Delta Logo
6:00 am - 1:56 pmMDW-PTY
6h 56m1 stop
Delta Logo
3:37 pm - 11:32 pmPTY-MDW
8h 55m1 stop
$592Delta
Find Deal
mar., nov. 4 - dom., nov. 9
Multiple Airlines Logo
6:20 am - 7:33 pmMDW-PTY
13h 13m1 stop
Multiple Airlines Logo
9:25 am - 10:03 pmPTY-MDW
13h 38m1 stop
$597Multiple Airlines
Find Deal
jue., oct. 30 - dom., nov. 2
Multiple Airlines Logo
6:20 am - 7:33 pmMDW-PTY
13h 13m1 stop
Multiple Airlines Logo
9:25 am - 6:39 pmPTY-MDW
9h 14m1 stop
$601Multiple Airlines
Find Deal
jue., oct. 23 - jue., oct. 30

Delta flights from Chicago Midway Airport to Panama City

Our best Delta deals on Chicago Midway Airport to Panama City flight tickets
Delta
Nov 29
MDW6:00 amChicago Midway
7h 12m
1 stop
PTY2:12 pmPanama City Tocumen Intl
Dec 3
PTY3:46 pmPanama City Tocumen Intl
8h 46m
1 stop
MDW11:32 pmChicago Midway
$465
Find similar
Delta
Jan 10
MDW9:30 amChicago Midway
9h 34m
2 stops
PTY8:04 pmPanama City Tocumen Intl
Jan 17
PTY8:05 amPanama City Tocumen Intl
9h 20m
1 stop
MDW4:25 pmChicago Midway
$470
Find similar
Delta
Mar 10
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 11
PTY2:20 pmPanama City Tocumen Intl
22h 15m
2 stops
MDW12:35 pmChicago Midway
$582
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

sáb. 11/29

6:00 am-2:12 pm

1 stop7h 12m

Panama City Tocumen Intl

mié. 12/3

3:46 pm-11:32 pm

1 stop8h 46m

$465

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

sáb. 1/10

9:30 am-8:04 pm

2 stops9h 34m

Panama City Tocumen Intl

sáb. 1/17

8:05 am-4:25 pm

1 stop9h 20m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

vie. 10/31

7:50 am-12:40 am

2 stops16h 50m

Panama City Tocumen Intl

vie. 11/7

9:33 pm-9:22 pm

1 stop24h 49m

$534

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

vie. 10/31

7:50 am-12:40 am

2 stops16h 50m

Panama City Tocumen Intl

lun. 11/10

9:11 am-12:30 am

1 stop16h 19m

$568

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mié. 3/11

2:20 pm-12:35 pm

2 stops22h 15m

$582

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

jue. 10/30

6:20 am-7:33 pm

1 stop13h 13m

Panama City Tocumen Intl

dom. 11/2

9:25 am-10:03 pm

1 stop13h 38m

$586

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mié. 3/11

2:20 pm-4:25 pm

1 stop26h 05m

$587

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 11/4

6:00 am-1:56 pm

1 stop6h 56m

Panama City Tocumen Intl

dom. 11/9

3:37 pm-11:32 pm

1 stop8h 55m

$592

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

jue. 10/30

6:20 am-7:33 pm

1 stop13h 13m

Panama City Tocumen Intl

dom. 11/2

9:25 am-10:03 pm

1 stop13h 38m

$597

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

jue. 10/23

6:20 am-7:33 pm

1 stop13h 13m

Panama City Tocumen Intl

jue. 10/30

9:25 am-6:39 pm

1 stop9h 14m

$601

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $538. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $608. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago Midway Airport to Panama City during this time can be as low as $510. Try not to purchase tickets at noon because they tend to be around $609. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Panama City (MDW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama City

Direct flights

None
There are no direct flights from Chicago Midway Airport to Panama City. There are no popular flight routes from Chicago Midway Airport to Panama City.
Search flight deals

  • How far is Chicago Midway to Panama City Tocumen Intl by plane?

    Chicago Midway and Panama City Tocumen Intl are 2319.5 mi apart from one another. By plane, this route typically takes 6h 55m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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vie. 10/17
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