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Cheap flights from Chicago Midway Airport to Panama City from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama City departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:15 am - 4:06 pm
MDW
-
PTY
8h 51m
1 stop
Multiple Airlines Logo
5:50 pm - 1:41 pm
PTY
-
MDW
19h 51m
2 stops
$522Multiple Airlines
Sun, Mar 1 - Wed, Mar 11
Multiple Airlines Logo
6:15 am - 4:06 pm
MDW
-
PTY
8h 51m
1 stop
Multiple Airlines Logo
5:50 pm - 1:56 pm
PTY
-
MDW
21h 06m
2 stops
$524Multiple Airlines
Sun, Feb 15 - Wed, Feb 18
Multiple Airlines Logo
6:15 am - 4:06 pm
MDW
-
PTY
8h 51m
1 stop
Multiple Airlines Logo
9:33 pm - 1:41 pm
PTY
-
MDW
16h 08m
1 stop
$540Multiple Airlines
Sun, Mar 1 - Wed, Mar 18
Multiple Airlines Logo
6:20 am - 8:34 pm
MDW
-
PTY
13h 14m
1 stop
Multiple Airlines Logo
10:26 am - 10:19 pm
PTY
-
MDW
12h 53m
1 stop
$541Multiple Airlines
Sun, Feb 1 - Thu, Feb 5
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
10:26 am - 8:54 pm
PTY
-
MDW
10h 28m
1 stop
$545Multiple Airlines
Tue, Mar 10 - Tue, Mar 17
Multiple Airlines Logo
7:30 am - 8:34 pm
MDW
-
PTY
12h 04m
1 stop
Multiple Airlines Logo
10:26 am - 8:54 pm
PTY
-
MDW
10h 28m
1 stop
$550Multiple Airlines
Thu, Mar 5 - Tue, Mar 10
Multiple Airlines Logo
6:25 am - 8:34 pm
MDW
-
PTY
13h 09m
1 stop
Multiple Airlines Logo
10:26 am - 10:24 pm
PTY
-
MDW
12h 58m
1 stop
$556Multiple Airlines
Sat, Feb 28 - Sat, Mar 7
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
13h 34m
1 stop
Multiple Airlines Logo
10:26 am - 10:29 pm
PTY
-
MDW
13h 03m
1 stop
$561Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
6:15 am - 4:06 pm
MDW
-
PTY
8h 51m
1 stop
Multiple Airlines Logo
9:33 pm - 1:41 pm
PTY
-
MDW
16h 08m
1 stop
$571Multiple Airlines
Sun, Mar 1 - Wed, Mar 11
Multiple Airlines Logo
6:15 am - 4:06 pm
MDW
-
PTY
8h 51m
1 stop
Multiple Airlines Logo
9:33 pm - 1:41 pm
PTY
-
MDW
16h 08m
1 stop
$572Multiple Airlines
Sun, Mar 1 - Wed, Mar 11

Delta flights from Chicago Midway Airport to Panama City

Our best Delta deals on Chicago Midway Airport to Panama City flight tickets
Delta
Apr 16
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 20
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$628
Delta
Mar 18
MDW6:00 amChicago Midway
7h 03m
1 stop
PTY1:03 pmPanama City Tocumen Intl
Mar 24
PTY2:28 pmPanama City Tocumen Intl
8h 03m
1 stop
MDW10:31 pmChicago Midway
$653
Delta
Mar 25
MDW6:00 amChicago Midway
7h 03m
1 stop
PTY1:03 pmPanama City Tocumen Intl
Mar 31
PTY2:28 pmPanama City Tocumen Intl
27h 26m
2 stops
MDW5:54 pmChicago Midway
$659

LATAM Airlines flights from Chicago Midway Airport to Panama City

Our best LATAM Airlines deals on Chicago Midway Airport to Panama City flight tickets
LATAM Airlines
Feb 2
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 5
PTY3:20 pmPanama City Tocumen Intl
8h 02m
1 stop
MDW10:22 pmChicago Midway
$968
LATAM Airlines
Jan 28
MDW6:14 pmChicago Midway
18h 41m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 31
PTY3:20 pmPanama City Tocumen Intl
8h 02m
1 stop
MDW10:22 pmChicago Midway
$1,170
LATAM Airlines
Jan 27
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 29
PTY3:20 pmPanama City Tocumen Intl
8h 02m
1 stop
MDW10:22 pmChicago Midway
$2,057

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Wed 3/11

5:50 pm-1:41 pm

2 stops19h 51m

$522

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 2/15

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Wed 2/18

5:50 pm-1:56 pm

2 stops21h 06m

$524

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Wed 3/18

9:33 pm-1:41 pm

1 stop16h 08m

$540

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 2/1

6:20 am-8:34 pm

1 stop13h 14m

Panama City Tocumen Intl

Thu 2/5

10:26 am-10:19 pm

1 stop12h 53m

$541

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/10

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Tue 3/17

10:26 am-8:54 pm

1 stop10h 28m

$545

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 3/5

7:30 am-8:34 pm

1 stop12h 04m

Panama City Tocumen Intl

Tue 3/10

10:26 am-8:54 pm

1 stop10h 28m

$550

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 2/28

6:25 am-8:34 pm

1 stop13h 09m

Panama City Tocumen Intl

Sat 3/7

10:26 am-10:24 pm

1 stop12h 58m

$556

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 2/22

6:00 am-8:34 pm

1 stop13h 34m

Panama City Tocumen Intl

Thu 2/26

10:26 am-10:29 pm

1 stop13h 03m

$561

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Wed 3/11

9:33 pm-1:41 pm

1 stop16h 08m

$571

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Wed 3/11

9:33 pm-1:41 pm

1 stop16h 08m

$572

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $526. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $584. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago Midway Airport to Panama City during this time can be as low as $496. Try not to purchase tickets in the morning because they tend to be around $577. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Panama City (MDW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama City

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Chicago Midway Airport to Panama City takes 6h 50m
There are no direct flights from Chicago Midway Airport to Panama City. There are no popular flight routes from Chicago Midway Airport to Panama City.
Search flight deals

  • How far is Chicago Midway to Panama City Tocumen Intl by plane?

    Chicago Midway and Panama City Tocumen Intl are 2319.5 mi apart from one another. By plane, this route typically takes 6h 50m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago Midway Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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