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Cheap flights from Mexico City to Santo Domingo from $192

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Santo Domingo departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
1:20 am - 4:14 pm
MEX
-
SDQ
12h 54m
1 stop
Copa Airlines Logo
8:37 am - 1:00 am
SDQ
-
MEX
18h 23m
1 stop
$339Copa Airlines
Sun, Mar 22 - Mon, Mar 30
Avianca Logo
11:10 pm - 4:50 pm
MEX
-
SDQ
15h 40m
1 stop
Avianca Logo
12:45 pm - 11:00 pm
SDQ
-
MEX
12h 15m
1 stop
$365Avianca
Fri, Feb 20 - Fri, May 22
Avianca Logo
12:40 am - 11:50 am
MEX
-
SDQ
9h 10m
1 stop
Avianca Logo
6:50 pm - 3:05 am
SDQ
-
MEX
10h 15m
1 stop
$370Avianca
Wed, Apr 15 - Mon, Apr 20
Copa Airlines Logo
5:50 am - 10:56 pm
MEX
-
SDQ
15h 06m
1 stop
Copa Airlines Logo
12:10 pm - 1:00 am
SDQ
-
MEX
14h 50m
1 stop
$372Copa Airlines
Thu, May 7 - Thu, May 14
Copa Airlines Logo
1:10 pm - 10:39 pm
MEX
-
SDQ
7h 29m
1 stop
Copa Airlines Logo
2:11 pm - 12:15 am
SDQ
-
MEX
12h 04m
1 stop
$388Copa Airlines
Thu, Feb 19 - Mon, Feb 23
Copa Airlines Logo
9:50 am - 2:20 am
MEX
-
SDQ
14h 30m
1 stop
Copa Airlines Logo
6:04 am - 10:05 pm
SDQ
-
MEX
18h 01m
1 stop
$392Copa Airlines
Mon, Apr 27 - Tue, May 5
Aeromexico Logo
12:15 am - 6:25 am
MEX
-
SDQ
4h 10mnonstop
Aeromexico Logo
11:01 am - 2:10 pm
SDQ
-
MEX
5h 09mnonstop
$398Aeromexico
Mon, Apr 6 - Tue, Apr 28
Copa Airlines Logo
5:50 am - 4:14 pm
MEX
-
SDQ
8h 24m
1 stop
Copa Airlines Logo
6:39 pm - 12:15 am
SDQ
-
MEX
7h 36m
1 stop
$413Copa Airlines
Sat, Apr 18 - Fri, May 1
Aeromexico Logo
12:15 am - 6:25 am
MEX
-
SDQ
4h 10mnonstop
Aeromexico Logo
11:01 am - 2:10 pm
SDQ
-
MEX
5h 09mnonstop
$419Aeromexico
Mon, Apr 6 - Tue, Apr 28
Avianca Logo
5:00 am - 4:50 pm
MEX
-
SDQ
9h 50m
1 stop
Avianca Logo
5:45 pm - 10:55 pm
SDQ
-
MEX
31h 10m
1 stop
$420Avianca
Thu, Feb 19 - Mon, Feb 23

Avianca flights from Mexico City to Santo Domingo

Our best Avianca deals on Mexico City to Santo Domingo flight tickets
Avianca
Feb 20
MEX11:10 pmMexico City Benito Juarez
15h 40m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
May 22
SDQ12:45 pmSanto Domingo Las Americas
12h 15m
1 stop
MEX11:00 pmMexico City Benito Juarez
$365
Avianca
May 21
MEX4:55 amMexico City Benito Juarez
11h 00m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
May 28
SDQ6:50 pmSanto Domingo Las Americas
10h 15m
1 stop
MEX3:05 amMexico City Benito Juarez
$369
Avianca
Feb 11
MEX12:40 amMexico City Benito Juarez
8h 45m
1 stop
SDQ11:25 amSanto Domingo Las Americas
Feb 19
SDQ5:45 pmSanto Domingo Las Americas
11h 15m
1 stop
MEX3:00 amMexico City Benito Juarez
$370

Copa Airlines flights from Mexico City to Santo Domingo

Our best Copa Airlines deals on Mexico City to Santo Domingo flight tickets
Copa Airlines
Mar 22
MEX1:20 amMexico City Benito Juarez
12h 54m
1 stop
SDQ4:14 pmSanto Domingo Las Americas
Mar 30
SDQ8:37 amSanto Domingo Las Americas
18h 23m
1 stop
MEX1:00 amMexico City Benito Juarez
$339
Copa Airlines
Feb 9
MEX1:20 amMexico City Benito Juarez
7h 30m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Feb 12
SDQ2:11 pmSanto Domingo Las Americas
12h 04m
1 stop
MEX12:15 amMexico City Benito Juarez
$344
Copa Airlines
Feb 10
MEX5:55 amMexico City Benito Juarez
14h 44m
1 stop
SDQ10:39 pmSanto Domingo Las Americas
Feb 16
SDQ11:57 amSanto Domingo Las Americas
14h 18m
1 stop
MEX12:15 amMexico City Benito Juarez
$345

momondo Fare Finder

 
Customize your flight search to find flights from Mexico City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Sun 3/22

1:20 am-4:14 pm

1 stop12h 54m

Santo Domingo Las Americas

Mon 3/30

8:37 am-1:00 am

1 stop18h 23m

$339

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 2/20

11:10 pm-4:50 pm

1 stop15h 40m

Santo Domingo Las Americas

Fri 5/22

12:45 pm-11:00 pm

1 stop12h 15m

$365

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 4/15

12:40 am-11:50 am

1 stop9h 10m

Santo Domingo Las Americas

Mon 4/20

6:50 pm-3:05 am

1 stop10h 15m

$370

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 5/7

5:50 am-10:56 pm

1 stop15h 06m

Santo Domingo Las Americas

Thu 5/14

12:10 pm-1:00 am

1 stop14h 50m

$372

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 2/19

1:10 pm-10:39 pm

1 stop7h 29m

Santo Domingo Las Americas

Mon 2/23

2:11 pm-12:15 am

1 stop12h 04m

$388

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 4/27

9:50 am-2:20 am

1 stop14h 30m

Santo Domingo Las Americas

Tue 5/5

6:04 am-10:05 pm

1 stop18h 01m

$392

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 4/6

12:15 am-6:25 am

Nonstop4h 10m

Santo Domingo Las Americas

Tue 4/28

11:01 am-2:10 pm

Nonstop5h 09m

$398

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Sat 4/18

5:50 am-4:14 pm

1 stop8h 24m

Santo Domingo Las Americas

Fri 5/1

6:39 pm-12:15 am

1 stop7h 36m

$413

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 4/6

12:15 am-6:25 am

Nonstop4h 10m

Santo Domingo Las Americas

Tue 4/28

11:01 am-2:10 pm

Nonstop5h 09m

$419

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 2/19

5:00 am-4:50 pm

1 stop9h 50m

Santo Domingo Las Americas

Mon 2/23

5:45 pm-10:55 pm

1 stop31h 10m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mexico City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until November to fly from Mexico City, when ticket prices are also cheap, with an average price of $320.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $332. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $642.

What is the cheapest Mexico City Benito Juarez to Santo Domingo Las Americas flight route?

Fly from Mexico City Benito Juarez to Santo Domingo Las Americas for the best Mexico City Benito Juarez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $335 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Mexico City for as low as $287 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Santo Domingo Las Americas flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Mexico City to Santo Domingo flights?

You could potentially save up to 82% on your flight if you consider stops on a Mexico City to Santo Domingo flight.

How have Mexico City to Santo Domingo flight prices changed over time?

As of February 2026, prices for Mexico City to Santo Domingo flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santo Domingo (MEX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santo Domingo

Fastest flight time

4h 15m

Direct flights

Every day

Airports in Santo Domingo

1 airport
The fastest flight from Mexico City to Santo Domingo takes 4h 15m
Direct flights go from Mexico City to Santo Domingo every day.
There is 1 airport in Santo Domingo. From Mexico City there are direct flights to Santo Domingo Las Americas (SDQ).
Search flight deals

  • How far is Mexico City Benito Juarez to Santo Domingo Las Americas by plane?

    Mexico City Benito Juarez and Santo Domingo Las Americas are 1907.2 mi apart from one another. By plane, this route typically takes 4h 15m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santo Domingo?

  • What is the most popular airline from Mexico City to Santo Domingo?

Best airlines flying from Mexico City to Santo Domingo

Compare and see reviews for airlines that fly from Mexico City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
ArajetPriceFrom $175Free CancellationRating
6.6
43 reviews
Search Arajet flights
Copa AirlinesPriceFrom $248Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
AeromexicoPriceFrom $325Free CancellationRating
7.4
1,577 reviews
Search Aeromexico flights

  • Aeromexico Flights From Mexico City to Santo Domingo

    Across 7 Aeromexico flights from Mexico City to Santo Domingo this week, the average price was $431, with the best Aeromexico deals starting from $325 round-trip. 1,577 users have rated Aeromexico on momondo, with an average score of 7.4/10.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mexico City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Mexico City to Santo Domingo with flexible booking policies on momondo?

Flights from Mexico City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mexico City to Santo Domingo?

momondo helps you find the best flight between Mexico City and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mexico City to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mexico City to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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