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Cheap flights from Mexico City to Santo Domingo from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Santo Domingo departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Santo Domingo

Cheap round-trip flights

Aeromexico Logo
12:30 am - 6:50 amMEX-SDQ
4h 20mnonstop
Aeromexico Logo
11:01 am - 1:50 pmSDQ-MEX
4h 49mnonstop
$354Aeromexico
Find Deal
Tue, Oct 14 - Fri, Oct 24
Copa Airlines Logo
1:40 am - 1:07 pmMEX-SDQ
9h 27m1 stop
Copa Airlines Logo
8:58 am - 1:00 amSDQ-MEX
18h 02m1 stop
$356Copa Airlines
Find Deal
Thu, Oct 2 - Sun, Oct 12
Avianca Logo
12:40 am - 5:15 pmMEX-SDQ
14h 35m1 stop
Avianca Logo
6:10 pm - 3:05 amSDQ-MEX
10h 55m1 stop
$363Avianca
Find Deal
Tue, Aug 26 - Wed, Sep 3
Copa Airlines Logo
3:30 pm - 2:26 amMEX-SDQ
8h 56m1 stop
Copa Airlines Logo
8:55 am - 10:05 pmSDQ-MEX
15h 10m1 stop
$372Copa Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 13
Copa Airlines Logo
1:20 am - 1:12 pmMEX-SDQ
9h 52m1 stop
Copa Airlines Logo
8:55 am - 10:05 pmSDQ-MEX
15h 10m1 stop
$390Copa Airlines
Find Deal
Fri, Nov 28 - Sat, Dec 13
Avianca Logo
4:55 am - 10:50 amMEX-SDQ
27h 55m1 stop
Avianca Logo
6:10 pm - 3:05 amSDQ-MEX
10h 55m1 stop
$395Avianca
Find Deal
Fri, Aug 29 - Fri, Sep 5
Aeromexico Logo
12:30 am - 6:50 amMEX-SDQ
4h 20mnonstop
Aeromexico Logo
11:01 am - 1:50 pmSDQ-MEX
4h 49mnonstop
$396Aeromexico
Find Deal
Tue, Oct 14 - Tue, Oct 21
Copa Airlines Logo
2:00 am - 1:07 pmMEX-SDQ
9h 07m1 stop
Copa Airlines Logo
11:57 am - 10:05 pmSDQ-MEX
12h 08m1 stop
$398Copa Airlines
Find Deal
Thu, Oct 9 - Thu, Oct 16
Copa Airlines Logo
1:10 pm - 10:25 pmMEX-SDQ
7h 15m1 stop
Copa Airlines Logo
11:55 am - 7:20 pmSDQ-MEX
9h 25m1 stop
$408Copa Airlines
Find Deal
Thu, Nov 13 - Thu, Nov 27
Copa Airlines Logo
1:40 am - 1:09 pmMEX-SDQ
9h 29m1 stop
Copa Airlines Logo
8:59 am - 1:00 amSDQ-MEX
18h 01m1 stop
$411Copa Airlines
Find Deal
Tue, Sep 23 - Sun, Sep 28

Aeromexico flights from Mexico City to Santo Domingo

Our best Aeromexico deals on Mexico City to Santo Domingo flight tickets
Aeromexico
Oct 14
MEX12:30 amMexico City Benito Juarez
4h 20m
SDQ6:50 amSanto Domingo Las Americas
Oct 24
SDQ11:01 amSanto Domingo Las Americas
4h 49m
MEX1:50 pmMexico City Benito Juarez
$354
Find similar
Aeromexico
Oct 14
MEX12:30 amMexico City Benito Juarez
4h 20m
SDQ6:50 amSanto Domingo Las Americas
Oct 21
SDQ11:01 amSanto Domingo Las Americas
4h 49m
MEX1:50 pmMexico City Benito Juarez
$396
Find similar
Aeromexico
Oct 9
MEX12:30 amMexico City Benito Juarez
4h 20m
SDQ6:50 amSanto Domingo Las Americas
Oct 16
SDQ11:01 amSanto Domingo Las Americas
4h 49m
MEX1:50 pmMexico City Benito Juarez
$417
Find similar

Copa Airlines flights from Mexico City to Santo Domingo

Our best Copa Airlines deals on Mexico City to Santo Domingo flight tickets
Copa Airlines
Oct 2
MEX1:40 amMexico City Benito Juarez
9h 27m
1 stop
SDQ1:07 pmSanto Domingo Las Americas
Oct 12
SDQ8:58 amSanto Domingo Las Americas
18h 02m
1 stop
MEX1:00 amMexico City Benito Juarez
$356
Find similar
Copa Airlines
Nov 29
MEX3:30 pmMexico City Benito Juarez
8h 56m
1 stop
SDQ2:26 amSanto Domingo Las Americas
Dec 13
SDQ8:55 amSanto Domingo Las Americas
15h 10m
1 stop
MEX10:05 pmMexico City Benito Juarez
$372
Find similar
Copa Airlines
Nov 28
MEX1:20 amMexico City Benito Juarez
9h 52m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
Dec 13
SDQ8:55 amSanto Domingo Las Americas
15h 10m
1 stop
MEX10:05 pmMexico City Benito Juarez
$390
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mexico City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 10/14

12:30 am-6:50 am

Nonstop4h 20m

Santo Domingo Las Americas

Fri 10/24

11:01 am-1:50 pm

Nonstop4h 49m

$354

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 10/2

1:40 am-1:07 pm

1 stop9h 27m

Santo Domingo Las Americas

Sun 10/12

8:58 am-1:00 am

1 stop18h 02m

$356

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 8/26

12:40 am-5:15 pm

1 stop14h 35m

Santo Domingo Las Americas

Wed 9/3

6:10 pm-3:05 am

1 stop10h 55m

$363

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Sat 11/29

3:30 pm-2:26 am

1 stop8h 56m

Santo Domingo Las Americas

Sat 12/13

8:55 am-10:05 pm

1 stop15h 10m

$372

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 11/28

1:20 am-1:12 pm

1 stop9h 52m

Santo Domingo Las Americas

Sat 12/13

8:55 am-10:05 pm

1 stop15h 10m

$390

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 8/29

4:55 am-10:50 am

1 stop27h 55m

Santo Domingo Las Americas

Fri 9/5

6:10 pm-3:05 am

1 stop10h 55m

$395

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 10/14

12:30 am-6:50 am

Nonstop4h 20m

Santo Domingo Las Americas

Tue 10/21

11:01 am-1:50 pm

Nonstop4h 49m

$396

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 10/9

2:00 am-1:07 pm

1 stop9h 07m

Santo Domingo Las Americas

Thu 10/16

11:57 am-10:05 pm

1 stop12h 08m

$398

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Thu 11/13

1:10 pm-10:25 pm

1 stop7h 15m

Santo Domingo Las Americas

Thu 11/27

11:55 am-7:20 pm

1 stop9h 25m

$408

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 9/23

1:40 am-1:09 pm

1 stop9h 29m

Santo Domingo Las Americas

Sun 9/28

8:59 am-1:00 am

1 stop18h 01m

$411

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mexico City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Mexico City and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in May, then you should wait until June to fly from Mexico City, when ticket prices are also cheap, with an average price of $316.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $337. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $479.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the morning when flights can be purchased for as low as $300. Try not to purchase tickets in the evening because they tend to be around $425. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Mexico City Benito Juarez to Santo Domingo Las Americas flight route?

Fly from Mexico City Benito Juarez to Santo Domingo Las Americas for the best Mexico City Benito Juarez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $350 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Mexico City for as low as $289 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Santo Domingo Las Americas flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Mexico City to Santo Domingo flights?

You could potentially save up to 58% on your flight if you consider stops on a Mexico City to Santo Domingo flight.

How have Mexico City to Santo Domingo flight prices changed over time?

As of July 2025, prices for Mexico City to Santo Domingo flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santo Domingo (MEX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santo Domingo

Best Price Found

$181

Fastest flight time

4h 20m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Mexico City in the past 72 hours is $181. The best round-trip flight deal from Mexico City to Santo Domingo found on momondo in the last 72 hours is $354.
The fastest flight from Mexico City to Santo Domingo takes 4h 20m
Direct flights go from Mexico City to Santo Domingo on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Aeromexico.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
Search flight deals

  • How far is Mexico City Benito Juarez to Santo Domingo Las Americas by plane?

    Mexico City Benito Juarez and Santo Domingo Las Americas are 1907.2 mi apart from one another. By plane, this route typically takes 4h 20m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santo Domingo?

  • What is the most popular airline from Mexico City to Santo Domingo?

Best airlines flying from Mexico City to Santo Domingo

Compare and see reviews for airlines that fly from Mexico City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
ArajetPriceFrom $175Free CancellationRating
7.1
32 reviews
Search Arajet flights
Copa AirlinesPriceFrom $272Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
AeromexicoPriceFrom $330Free CancellationRating
7.5
1,721 reviews
Search Aeromexico flights

  • Aeromexico Flights From Mexico City to Santo Domingo

    Across 2 Aeromexico flights from Mexico City to Santo Domingo this week, the average price was $447, with the best Aeromexico deals starting from $330 round-trip. 1,721 users have rated Aeromexico on momondo, with an average score of 7.5/10.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mexico City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Mexico City to Santo Domingo with flexible booking policies on momondo?

Flights from Mexico City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mexico City to Santo Domingo?

momondo helps you find the best flight between Mexico City and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mexico City to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mexico City to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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