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Cheap flights from Mexico City to Santo Domingo from $175

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Santo Domingo departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:25 am - 6:05 pm
MEX
-
SDQ
6h 40m1 stop
Copa Airlines Logo
7:05 pm - 12:15 am
SDQ
-
MEX
7h 10m1 stop
$332Copa Airlines
Sat, Jan 17 - Sat, Jan 24
Copa Airlines Logo
3:30 pm - 2:17 am
MEX
-
SDQ
8h 47m1 stop
Copa Airlines Logo
12:40 pm - 7:20 pm
SDQ
-
MEX
8h 40m1 stop
$339Copa Airlines
Wed, Jan 14 - Wed, Jan 21
Copa Airlines Logo
5:55 am - 6:05 pm
MEX
-
SDQ
10h 10m1 stop
Copa Airlines Logo
8:50 am - 7:20 pm
SDQ
-
MEX
12h 30m1 stop
$340Copa Airlines
Tue, Jan 13 - Tue, Jan 20
Copa Airlines Logo
9:25 am - 6:05 pm
MEX
-
SDQ
6h 40m1 stop
Copa Airlines Logo
7:05 pm - 12:15 am
SDQ
-
MEX
7h 10m1 stop
$347Copa Airlines
Tue, Feb 3 - Tue, Feb 10
Copa Airlines Logo
3:30 pm - 10:50 am
MEX
-
SDQ
17h 20m1 stop
Copa Airlines Logo
6:39 pm - 12:15 am
SDQ
-
MEX
7h 36m1 stop
$355Copa Airlines
Tue, Feb 10 - Tue, Feb 17
Copa Airlines Logo
9:25 am - 6:05 pm
MEX
-
SDQ
6h 40m1 stop
Copa Airlines Logo
7:05 pm - 10:05 pm
SDQ
-
MEX
29h 00m1 stop
$356Copa Airlines
Fri, Feb 6 - Fri, Feb 13
Avianca Logo
11:10 pm - 11:25 am
MEX
-
SDQ
10h 15m1 stop
Avianca Logo
5:45 pm - 3:00 am
SDQ
-
MEX
11h 15m1 stop
$367Avianca
Wed, Jan 14 - Fri, Jan 30
Copa Airlines Logo
5:55 am - 6:05 pm
MEX
-
SDQ
10h 10m1 stop
Copa Airlines Logo
2:11 pm - 12:15 am
SDQ
-
MEX
12h 04m1 stop
$368Copa Airlines
Sat, Jan 10 - Sat, Jan 17
Copa Airlines Logo
5:55 am - 6:05 pm
MEX
-
SDQ
10h 10m1 stop
Copa Airlines Logo
8:50 am - 12:15 am
SDQ
-
MEX
17h 25m1 stop
$369Copa Airlines
Fri, Jan 16 - Fri, Jan 23
Copa Airlines Logo
3:30 pm - 1:09 pm
MEX
-
SDQ
19h 39m1 stop
Copa Airlines Logo
6:39 pm - 10:05 pm
SDQ
-
MEX
29h 26m1 stop
$372Copa Airlines
Mon, Feb 9 - Mon, Feb 16

Copa Airlines flights from Mexico City to Santo Domingo

Our best Copa Airlines deals on Mexico City to Santo Domingo flight tickets
Copa Airlines
Jan 17
MEX5:55 amMexico City Benito Juarez
18h 22m
1 stop
SDQ2:17 amSanto Domingo Las Americas
Jan 24
SDQ7:05 pmSanto Domingo Las Americas
7h 10m
1 stop
MEX12:15 amMexico City Benito Juarez
$331
Find similar
Copa Airlines
Jan 17
MEX9:25 amMexico City Benito Juarez
6h 40m
1 stop
SDQ6:05 pmSanto Domingo Las Americas
Jan 24
SDQ7:05 pmSanto Domingo Las Americas
7h 10m
1 stop
MEX12:15 amMexico City Benito Juarez
$332
Find similar
Copa Airlines
Jan 14
MEX9:25 amMexico City Benito Juarez
11h 30m
1 stop
SDQ10:55 pmSanto Domingo Las Americas
Jan 21
SDQ12:40 pmSanto Domingo Las Americas
8h 40m
1 stop
MEX7:20 pmMexico City Benito Juarez
$338
Find similar

American Airlines flights from Mexico City to Santo Domingo

Our best American Airlines deals on Mexico City to Santo Domingo flight tickets
American Airlines
Dec 24
MEX5:30 amMexico City Benito Juarez
10h 26m
1 stop
SDQ5:56 pmSanto Domingo Las Americas
Dec 31
SDQ11:07 amSanto Domingo Las Americas
12h 08m
1 stop
MEX9:15 pmMexico City Benito Juarez
$653
Find similar
American Airlines
Dec 24
MEX11:20 amMexico City Benito Juarez
24h 56m
2 stops
SDQ2:16 pmSanto Domingo Las Americas
Dec 31
SDQ6:00 amSanto Domingo Las Americas
9h 55m
1 stop
MEX1:55 pmMexico City Benito Juarez
$657
Find similar
American Airlines
Dec 24
MEX1:45 pmMexico City Benito Juarez
24h 06m
2 stops
SDQ3:51 pmSanto Domingo Las Americas
Dec 31
SDQ6:00 amSanto Domingo Las Americas
17h 55m
2 stops
MEX9:55 pmMexico City Benito Juarez
$662
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mexico City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Sat 1/17

9:25 am-6:05 pm

1 stop6h 40m

Santo Domingo Las Americas

Sat 1/24

7:05 pm-12:15 am

1 stop7h 10m

$332

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 1/14

3:30 pm-2:17 am

1 stop8h 47m

Santo Domingo Las Americas

Wed 1/21

12:40 pm-7:20 pm

1 stop8h 40m

$339

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 1/13

5:55 am-6:05 pm

1 stop10h 10m

Santo Domingo Las Americas

Tue 1/20

8:50 am-7:20 pm

1 stop12h 30m

$340

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 2/3

9:25 am-6:05 pm

1 stop6h 40m

Santo Domingo Las Americas

Tue 2/10

7:05 pm-12:15 am

1 stop7h 10m

$347

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Tue 2/10

3:30 pm-10:50 am

1 stop17h 20m

Santo Domingo Las Americas

Tue 2/17

6:39 pm-12:15 am

1 stop7h 36m

$355

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 2/6

9:25 am-6:05 pm

1 stop6h 40m

Santo Domingo Las Americas

Fri 2/13

7:05 pm-10:05 pm

1 stop29h 00m

$356

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Wed 1/14

11:10 pm-11:25 am

1 stop10h 15m

Santo Domingo Las Americas

Fri 1/30

5:45 pm-3:00 am

1 stop11h 15m

$367

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Sat 1/10

5:55 am-6:05 pm

1 stop10h 10m

Santo Domingo Las Americas

Sat 1/17

2:11 pm-12:15 am

1 stop12h 04m

$368

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Fri 1/16

5:55 am-6:05 pm

1 stop10h 10m

Santo Domingo Las Americas

Fri 1/23

8:50 am-12:15 am

1 stop17h 25m

$369

Mexico CitySanto Domingo

MEX - SDQ

MEXSDQ

Mexico City Benito Juarez

Mon 2/9

3:30 pm-1:09 pm

1 stop19h 39m

Santo Domingo Las Americas

Mon 2/16

6:39 pm-10:05 pm

1 stop29h 26m

$372

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mexico City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until June to fly from Mexico City, when ticket prices are also cheap, with an average price of $316.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $332. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $642.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the morning when flights can be purchased for as low as $300. Try not to purchase tickets in the evening because they tend to be around $390. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Mexico City Benito Juarez to Santo Domingo Las Americas flight route?

Fly from Mexico City Benito Juarez to Santo Domingo Las Americas for the best Mexico City Benito Juarez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $336 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Mexico City for as low as $287 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Santo Domingo Las Americas flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Mexico City to Santo Domingo flights?

You could potentially save up to 50% on your flight if you consider stops on a Mexico City to Santo Domingo flight.

How have Mexico City to Santo Domingo flight prices changed over time?

As of December 2025, prices for Mexico City to Santo Domingo flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from Mexico City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santo Domingo (MEX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santo Domingo

Best Price Found

$375

Fastest flight time

4h 15m

Direct flights

Every day

Airports in Santo Domingo

1 airport
The best flight deal from Mexico City to Santo Domingo found on momondo in the last 72 hours is $375
The fastest flight from Mexico City to Santo Domingo takes 4h 15m
Direct flights go from Mexico City to Santo Domingo every day.
There is 1 airport in Santo Domingo. From Mexico City there are direct flights to Santo Domingo Las Americas (SDQ).
Search flight deals

  • How far is Mexico City Benito Juarez to Santo Domingo Las Americas by plane?

    Mexico City Benito Juarez and Santo Domingo Las Americas are 1907.2 mi apart from one another. By plane, this route typically takes 4h 15m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santo Domingo?

  • What is the most popular airline from Mexico City to Santo Domingo?

Best airlines flying from Mexico City to Santo Domingo

Compare and see reviews for airlines that fly from Mexico City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
ArajetPriceFrom $175Free CancellationRating
6.8
38 reviews
Search Arajet flights
AeromexicoPriceFrom $330Free CancellationRating
7.4
1,629 reviews
Search Aeromexico flights

  • Aeromexico Flights From Mexico City to Santo Domingo

    Across 7 Aeromexico flights from Mexico City to Santo Domingo this week, the average price was $407, with the best Aeromexico deals starting from $330 round-trip. 1,629 users have rated Aeromexico on momondo, with an average score of 7.4/10.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mexico City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Mexico City to Santo Domingo with flexible booking policies on momondo?

Flights from Mexico City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mexico City to Santo Domingo?

momondo helps you find the best flight between Mexico City and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mexico City to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mexico City to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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