Cheap flights from Mexico City to Santo Domingo from $201

If you don’t want to visit Santo Domingo in October, then you should wait until November to fly from Mexico City, when ticket prices are also cheap, with an average price of $324.

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $332. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $642.

Fly from Mexico City Benito Juarez to Santo Domingo Las Americas for the best Mexico City Benito Juarez - Santo Domingo Las Americas flight prices

You are more likely to see cheaper flights to Santo Domingo from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $337 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Mexico City for as low as $291 on momondo.

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 3% on your flight if you consider stops on a Mexico City to Santo Domingo flight.

Copa Airlines is the most popular carrier operating from Mexico City Benito Juarez to Santo Domingo Las Americas

Aeromexico, Arajet and Copa Airlines are the top three most popular airlines that fly to Santo Domingo from Mexico City according to our data. Aeromexico is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Santo Domingo. Keep in mind that there are 3 different airlines that fly to Santo Domingo on a routine basis, so you have a few additional options to choose from.

Historically, on average around 3% of flights between Mexico City and Santo Domingo have experienced a delay on any given week. The average delay length over the past 12 months has been 78 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Aeromexico have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

1 flights are operational daily from Mexico City to Santo Domingo as of April 2026. The most popular departure time for this route is 12:00AM, with 100% of flights per day taking off in the morning.

As of April 2026, there are 7 flights per week flying from Mexico City to Santo Domingo. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.