Cheap flights from Mexico City to Santo Domingo from $213

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Mexico City to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Aeromexico Logo
1:00 am - 7:15 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
4h 15mnonstop
Aeromexico Logo
11:01 am - 1:55 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
4h 54mnonstop
$396Aeromexico
Wed, Jan 13 - Thu, Jan 21
Aeromexico Logo
1:00 am - 7:16 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
4h 16mnonstop
Aeromexico Logo
11:02 am - 1:55 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
4h 53mnonstop
$396Aeromexico
Wed, Dec 2 - Thu, Dec 10
Aeromexico Logo
1:00 am - 7:15 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
4h 15mnonstop
Aeromexico Logo
11:01 am - 1:55 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
4h 54mnonstop
$396Aeromexico
Tue, Feb 2 - Wed, Feb 10
Aeromexico Logo
12:15 am - 6:42 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
4h 27mnonstop
Aeromexico Logo
11:01 am - 1:40 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
4h 39mnonstop
$396Aeromexico
Sun, Oct 4 - Mon, Oct 12
Copa Airlines Logo
2:10 am - 1:13 pmMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
9h 03m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:42 pm - 12:15 amSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
13h 33m1 stop Panama City Tocumen Intl
$418Copa Airlines
Wed, Sep 16 - Thu, Sep 24
Copa Airlines Logo
2:10 am - 11:42 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
7h 32m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:41 pm - 12:15 amSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
7h 34m1 stop Panama City Tocumen Intl
$420Copa Airlines
Mon, Sep 14 - Tue, Sep 22
Copa Airlines Logo
1:20 am - 11:42 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
8h 22m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:16 pm - 1:00 amSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
12h 44m1 stop Panama City Tocumen Intl
$420Copa Airlines
Thu, Sep 17 - Fri, Sep 25
Multiple Airlines Logo
11:10 pm - 11:50 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
10h 40m1 stop Bogotá El Dorado
Multiple Airlines Logo
11:01 am - 1:55 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
4h 54mnonstop
$439Multiple Airlines
Thu, Dec 24 - Thu, Dec 31
Avianca Logo
2:00 pm - 5:55 pmMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
25h 55m1 stop Bogotá El Dorado
Avianca Logo
6:50 pm - 11:00 pmSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
30h 10m1 stop Bogotá El Dorado
$450Avianca
Fri, Sep 18 - Mon, Sep 28
Multiple Airlines Logo
1:00 am - 7:15 amMEX  Mexico City Benito Juarez-SDQ Santo Domingo Las Americas
4h 15mnonstop
Multiple Airlines Logo
12:45 pm - 3:00 amSDQ  Santo Domingo Las Americas-MEX Mexico City Benito Juarez
16h 15m1 stop Bogotá El Dorado
$453Multiple Airlines
Thu, Jan 7 - Fri, Jan 15

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Avianca flights from Mexico City to Santo Domingo

Our best Avianca deals on Mexico City to Santo Domingo flight tickets
Avianca
Sep 18
MEX2:00 pmMexico City Benito Juarez
25h 55m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
Sep 28
SDQ6:50 pmSanto Domingo Las Americas
30h 10m
1 stop
MEX11:00 pmMexico City Benito Juarez
$450
Avianca
Nov 11
MEX11:10 pmMexico City Benito Juarez
10h 15m
1 stop
SDQ11:25 amSanto Domingo Las Americas
Nov 17
SDQ12:20 pmSanto Domingo Las Americas
12h 35m
1 stop
MEX10:55 pmMexico City Benito Juarez
$478
Avianca
Nov 10
MEX11:20 pmMexico City Benito Juarez
10h 30m
1 stop
SDQ11:50 amSanto Domingo Las Americas
Nov 17
SDQ12:45 pmSanto Domingo Las Americas
12h 10m
1 stop
MEX10:55 pmMexico City Benito Juarez
$479

Aeromexico flights from Mexico City to Santo Domingo

Our best Aeromexico deals on Mexico City to Santo Domingo flight tickets
Aeromexico
Oct 4
MEX12:15 amMexico City Benito Juarez
4h 27m
SDQ6:42 amSanto Domingo Las Americas
Oct 12
SDQ11:01 amSanto Domingo Las Americas
4h 39m
MEX1:40 pmMexico City Benito Juarez
$396
Aeromexico
Oct 6
MEX12:15 amMexico City Benito Juarez
4h 27m
SDQ6:42 amSanto Domingo Las Americas
Oct 13
SDQ11:01 amSanto Domingo Las Americas
4h 39m
MEX1:40 pmMexico City Benito Juarez
$416
Aeromexico
Nov 10
MEX1:00 amMexico City Benito Juarez
4h 16m
SDQ7:16 amSanto Domingo Las Americas
Nov 16
SDQ11:02 amSanto Domingo Las Americas
4h 53m
MEX1:55 pmMexico City Benito Juarez
$437

momondo Fare Finder

 
Use the filters below to find and compare flights from Mexico City to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Wed 1/13

1:00 am-7:15 am

Nonstop4h 15m

Santo Domingo Las Americas

Thu 1/21

11:01 am-1:55 pm

Nonstop4h 54m

$396

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Wed 12/2

1:00 am-7:16 am

Nonstop4h 16m

Santo Domingo Las Americas

Thu 12/10

11:02 am-1:55 pm

Nonstop4h 53m

$396

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Tue 2/2

1:00 am-7:15 am

Nonstop4h 15m

Santo Domingo Las Americas

Wed 2/10

11:01 am-1:55 pm

Nonstop4h 54m

$396
Quickest round-trip

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Sun 10/4

12:15 am-6:42 am

Nonstop4h 27m

Santo Domingo Las Americas

Mon 10/12

11:01 am-1:40 pm

Nonstop4h 39m

$396

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Wed 9/16

2:10 am-1:13 pm

1 stop9h 03m

Santo Domingo Las Americas

Thu 9/24

12:42 pm-12:15 am

1 stop13h 33m

$418

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Mon 9/14

2:10 am-11:42 am

1 stop7h 32m

Santo Domingo Las Americas

Tue 9/22

6:41 pm-12:15 am

1 stop7h 34m

$420

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 9/17

1:20 am-11:42 am

1 stop8h 22m

Santo Domingo Las Americas

Fri 9/25

2:16 pm-1:00 am

1 stop12h 44m

$420

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 12/24

11:10 pm-11:50 am

1 stop10h 40m

Santo Domingo Las Americas

Thu 12/31

11:01 am-1:55 pm

Nonstop4h 54m

$439

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Fri 9/18

2:00 pm-5:55 pm

1 stop25h 55m

Santo Domingo Las Americas

Mon 9/28

6:50 pm-11:00 pm

1 stop30h 10m

$450

Mexico CitySanto Domingo

MEX Mexico City Benito Juarez - SDQ Santo Domingo Las Americas

MEXSDQ

Mexico City Benito Juarez

Thu 1/7

1:00 am-7:15 am

Nonstop4h 15m

Santo Domingo Las Americas

Fri 1/15

12:45 pm-3:00 am

1 stop16h 15m

$453

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mexico City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Mexico City and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from $328 to $452.
The lowest price recently found on this route was $396.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in March, then you should wait until February to fly from Mexico City, when ticket prices are also cheap, with an average price of $342.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Friday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $318. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $616.

What is the cheapest Mexico City Benito Juarez to Santo Domingo Las Americas flight route?

Fly from Mexico City Benito Juarez to Santo Domingo Las Americas for the best Mexico City Benito Juarez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight from Mexico City to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $363 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Mexico City for as low as $329 on momondo.

What cabin class options are available on Mexico City to Santo Domingo flights?

There are 3 cabin classes available to choose from on Mexico City to Santo Domingo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Mexico City to Santo Domingo flights?

No. A direct flight is the cheapest option for a flight between Mexico City to Santo Domingo.

How have Mexico City to Santo Domingo flight prices changed over time?

As of August 2026, prices for Mexico City to Santo Domingo flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santo Domingo (MEX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santo Domingo

Best Price Found

$213

Fastest flight time

4h 15m

Direct flights

Every day

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Mexico City in the past 72 hours is $213. The best round-trip flight deal from Mexico City to Santo Domingo found on momondo in the last 72 hours is $396.
The fastest flight from Mexico City to Santo Domingo takes 4h 15m
Direct flights go from Mexico City to Santo Domingo every day.
There is 1 airport in Santo Domingo. From Mexico City there are direct flights to Santo Domingo Las Americas (SDQ).

Frequently asked questions about flying from Mexico City to Santo Domingo

  • How far is Mexico City Benito Juarez to Santo Domingo Las Americas by plane?

    Mexico City Benito Juarez and Santo Domingo Las Americas are 1907.2 mi apart from one another. By plane, this route typically takes 4h 15m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santo Domingo?

  • What is the most popular airline from Mexico City to Santo Domingo?

Best airlines flying from Mexico City to Santo Domingo

Compare and see reviews for airlines that fly from Mexico City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AeromexicoPriceFrom $235Free CancellationRating
7.4
1,471 reviews
Search Aeromexico flights
ArajetPriceFrom $256Free CancellationRating
6.1
54 reviews
Search Arajet flights
Copa AirlinesPriceFrom $345Free CancellationRating
7.6
1,555 reviews
Search Copa Airlines flights
  • Aeromexico Flights From Mexico City to Santo Domingo

    Across 7 Aeromexico flights from Mexico City to Santo Domingo this week, the average price was $480, with the best Aeromexico deals starting from $235 round-trip. 1,471 users have rated Aeromexico on momondo, with an average score of 7.4/10.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Mexico City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Mexico City to Santo Domingo with flexible booking policies on momondo?

Flights from Mexico City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Mexico City to Santo Domingo?

momondo helps you find the best flight between Mexico City and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mexico City to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mexico City to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Sun 9/20
Sun 9/27

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