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Cheap flights from Louisville to Santiago from $764

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santiago departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Louisville to Santiago (SDF-SCL)

Cheap round-trip flights

LATAM Airlines Logo
7:33 pm - 3:00 pmSDF-SCL
18h 27m2 stops
LATAM Airlines Logo
11:30 pm - 11:52 pmSCL-SDF
25h 22m2 stops
$764LATAM Airlines
Find Deal
lun., sep. 15 - mié., sep. 24
LATAM Airlines Logo
7:33 pm - 1:20 pmSDF-SCL
16h 47m2 stops
LATAM Airlines Logo
12:25 am - 6:36 pmSCL-SDF
19h 11m2 stops
$777LATAM Airlines
Find Deal
lun., sep. 15 - mar., sep. 23
Delta Logo
10:37 am - 6:35 amSDF-SCL
17h 58m2 stops
Delta Logo
8:50 am - 10:48 pmSCL-SDF
15h 58m2 stops
$784Delta
Find Deal
lun., nov. 17 - jue., nov. 27
Delta Logo
7:59 pm - 7:40 amSDF-SCL
33h 41m1 stop
Delta Logo
11:10 pm - 12:07 pmSCL-SDF
14h 57m1 stop
$791Delta
Find Deal
dom., nov. 16 - mié., nov. 26
American Airlines Logo
6:31 am - 7:55 amSDF-SCL
24h 24m1 stop
American Airlines Logo
9:55 pm - 11:58 pmSCL-SDF
27h 03m1 stop
$803American Airlines
Find Deal
lun., sep. 15 - mié., sep. 24
LATAM Airlines Logo
7:00 am - 7:00 amSDF-SCL
22h 00m1 stop
LATAM Airlines Logo
4:35 am - 11:56 pmSCL-SDF
21h 21m2 stops
$809LATAM Airlines
Find Deal
mié., nov. 19 - dom., nov. 23
United Airlines Logo
9:15 am - 8:50 amSDF-SCL
21h 35m1 stop
United Airlines Logo
10:45 pm - 1:25 pmSCL-SDF
16h 40m1 stop
$824United Airlines
Find Deal
sáb., nov. 22 - lun., nov. 24
Delta Logo
7:59 pm - 7:40 amSDF-SCL
33h 41m1 stop
Delta Logo
11:10 pm - 2:08 pmSCL-SDF
16h 58m1 stop
$831Delta
Find Deal
vie., nov. 21 - mié., nov. 26
Logo
6:03 pm - 6:00 amSDF-SCL
33h 57m1 stop
Logo
1:35 am - 11:45 pmSCL-SDF
24h 10m2 stops
$1,098
Find Deal
dom., nov. 16 - dom., nov. 23
Logo
6:03 pm - 6:00 amSDF-SCL
33h 57m1 stop
Logo
4:35 am - 11:45 pmSCL-SDF
21h 10m2 stops
$1,187
Find Deal
dom., nov. 16 - sáb., nov. 22

LATAM Airlines flights from Louisville to Santiago

Our best LATAM Airlines deals on Louisville to Santiago flight tickets
LATAM Airlines
Sep 15
SDF7:33 pmLouisville Intl
18h 27m
2 stops
SCL3:00 pmSantiago Arturo Merino Benitez
Sep 24
SCL11:30 pmSantiago Arturo Merino Benitez
25h 22m
2 stops
SDF11:52 pmLouisville Intl
$764
Find similar
LATAM Airlines
Sep 15
SDF7:33 pmLouisville Intl
16h 47m
2 stops
SCL1:20 pmSantiago Arturo Merino Benitez
Sep 23
SCL12:25 amSantiago Arturo Merino Benitez
19h 11m
2 stops
SDF6:36 pmLouisville Intl
$777
Find similar
LATAM Airlines
Nov 19
SDF7:00 amLouisville Intl
22h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Nov 23
SCL4:35 amSantiago Arturo Merino Benitez
21h 21m
2 stops
SDF11:56 pmLouisville Intl
$809
Find similar

American Airlines flights from Louisville to Santiago

Our best American Airlines deals on Louisville to Santiago flight tickets
American Airlines
Sep 15
SDF6:31 amLouisville Intl
24h 24m
1 stop
SCL7:55 amSantiago Arturo Merino Benitez
Sep 24
SCL9:55 pmSantiago Arturo Merino Benitez
27h 03m
1 stop
SDF11:58 pmLouisville Intl
$803
Find similar
American Airlines
Aug 31
SDF5:57 pmLouisville Intl
12h 58m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Sep 6
SCL9:55 pmSantiago Arturo Merino Benitez
26h 03m
1 stop
SDF11:58 pmLouisville Intl
$1,197
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 25, 2025.
Use the filters below to find and compare flights from Louisville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

lun. 9/15

7:33 pm-3:00 pm

2 stops18h 27m

Santiago Arturo Merino Benitez

mié. 9/24

11:30 pm-11:52 pm

2 stops25h 22m

$764

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

lun. 9/15

7:33 pm-1:20 pm

2 stops16h 47m

Santiago Arturo Merino Benitez

mar. 9/23

12:25 am-6:36 pm

2 stops19h 11m

$777

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

lun. 11/17

10:37 am-6:35 am

2 stops17h 58m

Santiago Arturo Merino Benitez

jue. 11/27

8:50 am-10:48 pm

2 stops15h 58m

$784

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

dom. 11/16

7:59 pm-7:40 am

1 stop33h 41m

Santiago Arturo Merino Benitez

mié. 11/26

11:10 pm-12:07 pm

1 stop14h 57m

$791

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

lun. 9/15

6:31 am-7:55 am

1 stop24h 24m

Santiago Arturo Merino Benitez

mié. 9/24

9:55 pm-11:58 pm

1 stop27h 03m

$803

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

mié. 11/19

7:00 am-7:00 am

1 stop22h 00m

Santiago Arturo Merino Benitez

dom. 11/23

4:35 am-11:56 pm

2 stops21h 21m

$809

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

sáb. 11/22

9:15 am-8:50 am

1 stop21h 35m

Santiago Arturo Merino Benitez

lun. 11/24

10:45 pm-1:25 pm

1 stop16h 40m

$824

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

vie. 11/21

7:59 pm-7:40 am

1 stop33h 41m

Santiago Arturo Merino Benitez

mié. 11/26

11:10 pm-2:08 pm

1 stop16h 58m

$831

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

dom. 11/16

6:03 pm-6:00 am

1 stop33h 57m

Santiago Arturo Merino Benitez

dom. 11/23

1:35 am-11:45 pm

2 stops24h 10m

$1,098

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

dom. 11/16

6:03 pm-6:00 am

1 stop33h 57m

Santiago Arturo Merino Benitez

sáb. 11/22

4:35 am-11:45 pm

2 stops21h 10m

$1,187

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Louisville to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $632. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Monday is $1,634.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Louisville to Santiago when you can find flight prices for as low as $872. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,086 per ticket.

Can stopping save me money on Louisville to Santiago flights?

You could potentially save up to 4% on your flight if you consider stops on a Louisville to Santiago flight.

When to book flights from Louisville to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santiago (SDF to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santiago

Direct flights

None
There are no direct flights from Louisville to Santiago. There are no popular flight routes from Louisville to Santiago.
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  • How far is Louisville Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5044.2 mi away from Louisville Intl. 12h 07m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How old do you have to be to fly from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Louisville with this policy.

How can momondo help me find flights from Louisville to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Louisville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Louisville to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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