Cheap flights from Louisville to Santiago from $1,180

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santiago departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Louisville to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:10 am - 8:00 am
SDF
-
SCL
19h 50m
2 stops
American Airlines Logo
9:30 pm - 3:28 pm
SCL
-
SDF
18h 58m
2 stops
$1,180American Airlines
Thu, Sep 10 - Sun, Sep 20
Copa Airlines Logo
6:15 am - 11:26 pm
SDF
-
SCL
17h 11m
2 stops
Copa Airlines Logo
12:06 am - 7:06 pm
SCL
-
SDF
19h 00m
2 stops
$1,229Copa Airlines
Sun, Aug 9 - Fri, Aug 21
LATAM Airlines Logo
6:00 pm - 8:15 am
SDF
-
SCL
13h 15m
1 stop
LATAM Airlines Logo
11:05 pm - 8:51 am
SCL
-
SDF
34h 46m
2 stops
$1,255LATAM Airlines
Thu, Sep 10 - Sun, Sep 20
LATAM Airlines Logo
3:43 pm - 8:15 am
SDF
-
SCL
15h 32m
1 stop
LATAM Airlines Logo
12:05 am - 11:59 pm
SCL
-
SDF
24h 54m
2 stops
$1,281LATAM Airlines
Thu, Sep 10 - Sun, Sep 20
LATAM Airlines Logo
1:15 pm - 5:45 am
SDF
-
SCL
15h 30m
2 stops
LATAM Airlines Logo
12:05 am - 11:59 pm
SCL
-
SDF
24h 54m
2 stops
$1,286LATAM Airlines
Thu, Sep 10 - Sun, Sep 20
LATAM Airlines Logo
1:15 pm - 1:25 pm
SDF
-
SCL
23h 10m
3 stops
LATAM Airlines Logo
10:30 pm - 11:59 pm
SCL
-
SDF
26h 29m
2 stops
$1,291LATAM Airlines
Thu, Sep 10 - Sun, Sep 20
American Airlines Logo
6:00 am - 7:05 am
SDF
-
SCL
25h 05m
1 stop
American Airlines Logo
8:50 pm - 5:23 pm
SCL
-
SDF
20h 33m
2 stops
$1,293American Airlines
Sun, Aug 9 - Sat, Aug 22
American Airlines Logo
1:22 pm - 8:00 am
SDF
-
SCL
17h 38m
2 stops
American Airlines Logo
9:30 pm - 4:22 pm
SCL
-
SDF
19h 52m
2 stops
$1,300American Airlines
Sun, Oct 4 - Wed, Oct 7
LATAM Airlines Logo
6:00 pm - 8:15 am
SDF
-
SCL
13h 15m
1 stop
LATAM Airlines Logo
8:40 pm - 12:20 pm
SCL
-
SDF
16h 40m
1 stop
$1,305LATAM Airlines
Thu, Sep 10 - Sun, Sep 20
American Airlines Logo
6:00 am - 8:00 am
SDF
-
SCL
25h 00m
1 stop
American Airlines Logo
9:30 pm - 2:51 pm
SCL
-
SDF
18h 21m
2 stops
$1,313American Airlines
Sun, Oct 4 - Wed, Oct 7

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

American Airlines flights from Louisville to Santiago

Our best American Airlines deals on Louisville to Santiago flight tickets
American Airlines
Sep 10
SDF11:10 amLouisville Intl
19h 50m
2 stops
SCL8:00 amSantiago Arturo Merino Benitez
Sep 20
SCL9:30 pmSantiago Arturo Merino Benitez
18h 58m
2 stops
SDF3:28 pmLouisville Intl
$1,180
American Airlines
Aug 9
SDF6:00 amLouisville Intl
25h 05m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
Aug 22
SCL8:50 pmSantiago Arturo Merino Benitez
20h 33m
2 stops
SDF5:23 pmLouisville Intl
$1,293
American Airlines
Oct 4
SDF1:22 pmLouisville Intl
17h 38m
2 stops
SCL8:00 amSantiago Arturo Merino Benitez
Oct 7
SCL9:30 pmSantiago Arturo Merino Benitez
19h 52m
2 stops
SDF4:22 pmLouisville Intl
$1,300

LATAM Airlines flights from Louisville to Santiago

Our best LATAM Airlines deals on Louisville to Santiago flight tickets
LATAM Airlines
Sep 10
SDF6:00 pmLouisville Intl
13h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Sep 20
SCL11:05 pmSantiago Arturo Merino Benitez
34h 46m
2 stops
SDF8:51 amLouisville Intl
$1,255
LATAM Airlines
Sep 10
SDF3:43 pmLouisville Intl
15h 32m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Sep 20
SCL12:05 amSantiago Arturo Merino Benitez
24h 54m
2 stops
SDF11:59 pmLouisville Intl
$1,281
LATAM Airlines
Sep 10
SDF1:15 pmLouisville Intl
15h 30m
2 stops
SCL5:45 amSantiago Arturo Merino Benitez
Sep 20
SCL12:05 amSantiago Arturo Merino Benitez
24h 54m
2 stops
SDF11:59 pmLouisville Intl
$1,286

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Louisville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

11:10 am-8:00 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Sun 9/20

9:30 pm-3:28 pm

2 stops18h 58m

$1,180

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Sun 8/9

6:15 am-11:26 pm

2 stops17h 11m

Santiago Arturo Merino Benitez

Fri 8/21

12:06 am-7:06 pm

2 stops19h 00m

$1,229

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

6:00 pm-8:15 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Sun 9/20

11:05 pm-8:51 am

2 stops34h 46m

$1,255

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

3:43 pm-8:15 am

1 stop15h 32m

Santiago Arturo Merino Benitez

Sun 9/20

12:05 am-11:59 pm

2 stops24h 54m

$1,281

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

1:15 pm-5:45 am

2 stops15h 30m

Santiago Arturo Merino Benitez

Sun 9/20

12:05 am-11:59 pm

2 stops24h 54m

$1,286

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

1:15 pm-1:25 pm

3 stops23h 10m

Santiago Arturo Merino Benitez

Sun 9/20

10:30 pm-11:59 pm

2 stops26h 29m

$1,291

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Sun 8/9

6:00 am-7:05 am

1 stop25h 05m

Santiago Arturo Merino Benitez

Sat 8/22

8:50 pm-5:23 pm

2 stops20h 33m

$1,293

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Sun 10/4

1:22 pm-8:00 am

2 stops17h 38m

Santiago Arturo Merino Benitez

Wed 10/7

9:30 pm-4:22 pm

2 stops19h 52m

$1,300
Quickest round-trip

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 9/10

6:00 pm-8:15 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Sun 9/20

8:40 pm-12:20 pm

1 stop16h 40m

$1,305

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Sun 10/4

6:00 am-8:00 am

1 stop25h 00m

Santiago Arturo Merino Benitez

Wed 10/7

9:30 pm-2:51 pm

2 stops18h 21m

$1,313

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Louisville to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Louisville to Santiago flights?

You could potentially save up to 20% on your flight if you consider stops on a Louisville to Santiago flight.

When to book flights from Louisville to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santiago (SDF to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santiago

Fastest flight time

32h 40m

Direct flights

None
The fastest flight from Louisville to Santiago takes 32h 40m
There are no direct flights from Louisville to Santiago. There are no popular flight routes from Louisville to Santiago.

Frequently asked questions about flying from Louisville to Santiago

  • How far is Louisville Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5044.2 mi away from Louisville Intl. 32h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How old do you have to be to fly from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Louisville with this policy.

How can momondo help me find flights from Louisville to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Louisville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Louisville to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 8/2
Sun 8/9

Find better results for your trip to Chile