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Cheap flights from Louisville to Santiago from $764

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santiago departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:13 pm - 8:15 am
SDF
-
SCL
16h 02m1 stop
American Airlines Logo
10:30 pm - 10:02 am
SCL
-
SDF
13h 32m1 stop
$764American Airlines
Tue, Jan 20 - Wed, Jan 28
United Airlines Logo
9:15 am - 8:50 am
SDF
-
SCL
21h 35m1 stop
United Airlines Logo
10:45 pm - 1:24 pm
SCL
-
SDF
16h 39m2 stops
$769United Airlines
Tue, Jan 20 - Wed, Jan 28
Multiple Airlines Logo
3:36 pm - 11:25 pm
SDF
-
SCL
29h 49m3 stops
Multiple Airlines Logo
3:00 pm - 2:41 pm
SCL
-
SDF
25h 41m2 stops
$779Multiple Airlines
Tue, Jan 20 - Wed, Jan 28
American Airlines Logo
11:55 am - 7:05 am
SDF
-
SCL
19h 10m2 stops
American Airlines Logo
8:50 pm - 7:44 pm
SCL
-
SDF
22h 54m2 stops
$809American Airlines
Thu, Apr 16 - Tue, Apr 28
American Airlines Logo
10:48 am - 7:05 am
SDF
-
SCL
20h 17m2 stops
American Airlines Logo
8:50 pm - 11:41 pm
SCL
-
SDF
26h 51m1 stop
$819American Airlines
Thu, Apr 16 - Tue, Apr 28
American Airlines Logo
6:44 am - 7:05 am
SDF
-
SCL
24h 21m1 stop
American Airlines Logo
8:50 pm - 11:41 pm
SCL
-
SDF
26h 51m1 stop
$824American Airlines
Thu, Apr 16 - Tue, Apr 28
Multiple Airlines Logo
3:36 pm - 11:25 pm
SDF
-
SCL
29h 49m3 stops
Multiple Airlines Logo
3:45 pm - 2:41 pm
SCL
-
SDF
24h 56m3 stops
$867Multiple Airlines
Tue, Jan 20 - Wed, Jan 28
Delta Logo
5:45 pm - 7:00 am
SDF
-
SCL
13h 15m1 stop
Delta Logo
8:40 pm - 4:52 pm
SCL
-
SDF
20h 12m1 stop
$874Delta
Mon, Apr 13 - Mon, Apr 27
Delta Logo
7:45 pm - 7:00 am
SDF
-
SCL
11h 15m1 stop
Delta Logo
10:55 pm - 6:43 pm
SCL
-
SDF
19h 48m1 stop
$914Delta
Fri, Apr 17 - Wed, Apr 29
Delta Logo
5:45 pm - 7:00 am
SDF
-
SCL
13h 15m1 stop
Delta Logo
8:40 pm - 4:52 pm
SCL
-
SDF
20h 12m1 stop
$954Delta
Fri, Apr 17 - Fri, May 1

American Airlines flights from Louisville to Santiago

Our best American Airlines deals on Louisville to Santiago flight tickets
American Airlines
Jan 20
SDF2:13 pmLouisville Intl
16h 02m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Jan 28
SCL10:30 pmSantiago Arturo Merino Benitez
13h 32m
1 stop
SDF10:02 amLouisville Intl
$764
Find similar
American Airlines
Apr 16
SDF11:55 amLouisville Intl
19h 10m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
Apr 28
SCL8:50 pmSantiago Arturo Merino Benitez
22h 54m
2 stops
SDF7:44 pmLouisville Intl
$809
Find similar
American Airlines
Apr 16
SDF10:48 amLouisville Intl
20h 17m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
Apr 28
SCL8:50 pmSantiago Arturo Merino Benitez
26h 51m
1 stop
SDF11:41 pmLouisville Intl
$819
Find similar

United Airlines flights from Louisville to Santiago

Our best United Airlines deals on Louisville to Santiago flight tickets
United Airlines
Jan 20
SDF9:15 amLouisville Intl
21h 35m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 28
SCL10:45 pmSantiago Arturo Merino Benitez
16h 39m
2 stops
SDF1:24 pmLouisville Intl
$769
Find similar
United Airlines
Jan 26
SDF9:15 amLouisville Intl
21h 35m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 29
SCL10:45 pmSantiago Arturo Merino Benitez
23h 09m
1 stop
SDF7:54 pmLouisville Intl
$1,124
Find similar
United Airlines
Jan 26
SDF3:30 pmLouisville Intl
15h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 29
SCL10:45 pmSantiago Arturo Merino Benitez
16h 39m
2 stops
SDF1:24 pmLouisville Intl
$1,129
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Louisville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 1/20

2:13 pm-8:15 am

1 stop16h 02m

Santiago Arturo Merino Benitez

Wed 1/28

10:30 pm-10:02 am

1 stop13h 32m

$764

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 1/20

9:15 am-8:50 am

1 stop21h 35m

Santiago Arturo Merino Benitez

Wed 1/28

10:45 pm-1:24 pm

2 stops16h 39m

$769

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 1/20

3:36 pm-11:25 pm

3 stops29h 49m

Santiago Arturo Merino Benitez

Wed 1/28

3:00 pm-2:41 pm

2 stops25h 41m

$779

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 4/16

11:55 am-7:05 am

2 stops19h 10m

Santiago Arturo Merino Benitez

Tue 4/28

8:50 pm-7:44 pm

2 stops22h 54m

$809

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 4/16

10:48 am-7:05 am

2 stops20h 17m

Santiago Arturo Merino Benitez

Tue 4/28

8:50 pm-11:41 pm

1 stop26h 51m

$819

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Thu 4/16

6:44 am-7:05 am

1 stop24h 21m

Santiago Arturo Merino Benitez

Tue 4/28

8:50 pm-11:41 pm

1 stop26h 51m

$824

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 1/20

3:36 pm-11:25 pm

3 stops29h 49m

Santiago Arturo Merino Benitez

Wed 1/28

3:45 pm-2:41 pm

3 stops24h 56m

$867

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 4/13

5:45 pm-7:00 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Mon 4/27

8:40 pm-4:52 pm

1 stop20h 12m

$874

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Fri 4/17

7:45 pm-7:00 am

1 stop11h 15m

Santiago Arturo Merino Benitez

Wed 4/29

10:55 pm-6:43 pm

1 stop19h 48m

$914

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Fri 4/17

5:45 pm-7:00 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Fri 5/1

8:40 pm-4:52 pm

1 stop20h 12m

$954

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Louisville to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $977. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Monday is $1,634.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Louisville to Santiago when you can find flight prices for as low as $872. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,086 per ticket.

Can stopping save me money on Louisville to Santiago flights?

You could potentially save up to 9% on your flight if you consider stops on a Louisville to Santiago flight.

When to book flights from Louisville to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santiago (SDF to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santiago

Fastest flight time

15h 20m

Direct flights

None
The fastest flight from Louisville to Santiago takes 15h 20m
There are no direct flights from Louisville to Santiago. There are no popular flight routes from Louisville to Santiago.
Search flight deals

  • How far is Louisville Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5044.2 mi away from Louisville Intl. 15h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How old do you have to be to fly from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Louisville with this policy.

How can momondo help me find flights from Louisville to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Louisville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Louisville to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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