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Cheap flights from Louisville to Santiago from $335

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santiago departing on 12/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:30 pm - 8:50 am
SDF
-
SCL
15h 20m1 stop
United Airlines Logo
9:45 pm - 1:32 pm
SCL
-
SDF
16h 47m1 stop
$764United Airlines
Tue, Mar 3 - Mon, Mar 9
United Airlines Logo
2:05 pm - 8:50 am
SDF
-
SCL
16h 45m2 stops
United Airlines Logo
9:45 pm - 4:46 pm
SCL
-
SDF
20h 01m2 stops
$769United Airlines
Tue, Mar 3 - Mon, Mar 9
LATAM Airlines Logo
12:11 pm - 11:06 am
SDF
-
SCL
20h 55m3 stops
LATAM Airlines Logo
6:40 am - 11:57 pm
SCL
-
SDF
18h 17m2 stops
$1,008LATAM Airlines
Tue, Mar 3 - Mon, Mar 9
United Airlines Logo
9:15 am - 8:50 am
SDF
-
SCL
21h 35m1 stop
United Airlines Logo
10:45 pm - 7:54 pm
SCL
-
SDF
23h 09m1 stop
$1,124United Airlines
Mon, Jan 26 - Thu, Jan 29
United Airlines Logo
11:10 am - 8:50 am
SDF
-
SCL
19h 40m2 stops
United Airlines Logo
10:45 pm - 1:14 pm
SCL
-
SDF
16h 29m1 stop
$1,129United Airlines
Mon, Jan 26 - Thu, Jan 29
LATAM Airlines Logo
10:13 am - 5:35 am
SDF
-
SCL
17h 22m2 stops
LATAM Airlines Logo
7:15 am - 11:50 pm
SCL
-
SDF
18h 35m3 stops
$2,242LATAM Airlines
Mon, Jan 26 - Thu, Jan 29
LATAM Airlines Logo
10:13 am - 5:35 am
SDF
-
SCL
17h 22m2 stops
LATAM Airlines Logo
7:15 am - 11:50 pm
SCL
-
SDF
18h 35m3 stops
$3,839LATAM Airlines
Mon, Jan 26 - Thu, Jan 29

United Airlines flights from Louisville to Santiago

Our best United Airlines deals on Louisville to Santiago flight tickets
United Airlines
Mar 3
SDF3:30 pmLouisville Intl
15h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 9
SCL9:45 pmSantiago Arturo Merino Benitez
16h 47m
1 stop
SDF1:32 pmLouisville Intl
$764
Find similar
United Airlines
Mar 3
SDF9:15 amLouisville Intl
21h 35m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 9
SCL9:45 pmSantiago Arturo Merino Benitez
20h 01m
2 stops
SDF4:46 pmLouisville Intl
$769
Find similar
United Airlines
Jan 26
SDF9:15 amLouisville Intl
21h 35m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 29
SCL10:45 pmSantiago Arturo Merino Benitez
23h 09m
1 stop
SDF7:54 pmLouisville Intl
$1,124
Find similar

LATAM Airlines flights from Louisville to Santiago

Our best LATAM Airlines deals on Louisville to Santiago flight tickets
LATAM Airlines
Mar 3
SDF12:11 pmLouisville Intl
20h 55m
3 stops
SCL11:06 amSantiago Arturo Merino Benitez
Mar 9
SCL6:40 amSantiago Arturo Merino Benitez
18h 17m
2 stops
SDF11:57 pmLouisville Intl
$1,008
Find similar
LATAM Airlines
Jan 26
SDF10:13 amLouisville Intl
17h 22m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Jan 29
SCL7:15 amSantiago Arturo Merino Benitez
18h 35m
3 stops
SDF11:50 pmLouisville Intl
$2,242
Find similar
LATAM Airlines
Jan 26
SDF10:13 amLouisville Intl
17h 22m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Jan 29
SCL7:15 amSantiago Arturo Merino Benitez
18h 35m
3 stops
SDF11:50 pmLouisville Intl
$3,839
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Louisville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 3/3

3:30 pm-8:50 am

1 stop15h 20m

Santiago Arturo Merino Benitez

Mon 3/9

9:45 pm-1:32 pm

1 stop16h 47m

$764

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 3/3

2:05 pm-8:50 am

2 stops16h 45m

Santiago Arturo Merino Benitez

Mon 3/9

9:45 pm-4:46 pm

2 stops20h 01m

$769

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 3/3

12:11 pm-11:06 am

3 stops20h 55m

Santiago Arturo Merino Benitez

Mon 3/9

6:40 am-11:57 pm

2 stops18h 17m

$1,008

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 1/26

9:15 am-8:50 am

1 stop21h 35m

Santiago Arturo Merino Benitez

Thu 1/29

10:45 pm-7:54 pm

1 stop23h 09m

$1,124

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 1/26

11:10 am-8:50 am

2 stops19h 40m

Santiago Arturo Merino Benitez

Thu 1/29

10:45 pm-1:14 pm

1 stop16h 29m

$1,129

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 1/26

10:13 am-5:35 am

2 stops17h 22m

Santiago Arturo Merino Benitez

Thu 1/29

7:15 am-11:50 pm

3 stops18h 35m

$2,242

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 1/26

10:13 am-5:35 am

2 stops17h 22m

Santiago Arturo Merino Benitez

Thu 1/29

7:15 am-11:50 pm

3 stops18h 35m

$3,839

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 12/30

2:55 pm-10:15 pm

3 stops29h 20m

$335

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Tue 12/30

5:05 am-8:44 pm

2 stops37h 39m

$352

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 12/29

5:05 am-5:30 am

3 stops46h 25m

$423

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Louisville to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $977. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Monday is $1,634.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Louisville to Santiago when you can find flight prices for as low as $872. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,086 per ticket.

Can stopping save me money on Louisville to Santiago flights?

You could potentially save up to 9% on your flight if you consider stops on a Louisville to Santiago flight.

When to book flights from Louisville to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santiago (SDF to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santiago

Fastest flight time

15h 20m

Direct flights

None
The fastest flight from Louisville to Santiago takes 15h 20m
There are no direct flights from Louisville to Santiago. There are no popular flight routes from Louisville to Santiago.
Search flight deals

  • How far is Louisville Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5044.2 mi away from Louisville Intl. 15h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How old do you have to be to fly from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Louisville with this policy.

How can momondo help me find flights from Louisville to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Louisville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Louisville to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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