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Cheap flights from Knoxville to Guatemala City from $220

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala City departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Guatemala City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:39 pm - 5:00 am
TYS
-
GUA
16h 21m1 stop
Multiple Airlines Logo
1:28 pm - 1:40 pm
GUA
-
TYS
23h 12m1 stop
$363Multiple Airlines
Thu, Jan 22 - Thu, Feb 5
Multiple Airlines Logo
9:32 pm - 12:24 pm
TYS
-
GUA
15h 52m1 stop
Multiple Airlines Logo
1:29 pm - 11:27 pm
GUA
-
TYS
8h 58m1 stop
$375Multiple Airlines
Thu, Feb 19 - Thu, Mar 5
Multiple Airlines Logo
5:56 pm - 11:20 am
TYS
-
GUA
42h 24m2 stops
Multiple Airlines Logo
1:29 pm - 11:27 pm
GUA
-
TYS
8h 58m1 stop
$384Multiple Airlines
Thu, Feb 19 - Thu, Mar 5
Multiple Airlines Logo
1:39 pm - 5:00 am
TYS
-
GUA
16h 21m1 stop
Multiple Airlines Logo
1:28 pm - 12:05 pm
GUA
-
TYS
21h 37m2 stops
$399Multiple Airlines
Thu, Jan 22 - Thu, Feb 5
Avianca Logo
7:20 pm - 5:00 am
TYS
-
GUA
10h 40m1 stop
Avianca Logo
7:10 pm - 10:57 am
GUA
-
TYS
14h 47m1 stop
$452Avianca
Mon, Jan 26 - Fri, Jan 30
United Airlines Logo
9:10 am - 7:39 pm
TYS
-
GUA
11h 29m1 stop
United Airlines Logo
2:10 am - 7:55 pm
GUA
-
TYS
16h 45m1 stop
$526United Airlines
Thu, Feb 19 - Tue, Mar 3
American Airlines Logo
6:00 am - 2:54 pm
TYS
-
GUA
9h 54m2 stops
American Airlines Logo
7:00 am - 9:28 pm
GUA
-
TYS
13h 28m2 stops
$530American Airlines
Thu, Feb 19 - Wed, Mar 4
Avianca Logo
7:20 pm - 5:00 am
TYS
-
GUA
10h 40m1 stop
Avianca Logo
7:10 pm - 10:57 am
GUA
-
TYS
14h 47m1 stop
$536Avianca
Mon, Jan 26 - Fri, Jan 30
American Airlines Logo
8:09 am - 9:05 pm
TYS
-
GUA
13h 56m2 stops
American Airlines Logo
7:00 am - 6:46 pm
GUA
-
TYS
10h 46m2 stops
$560American Airlines
Thu, Jan 22 - Thu, Feb 5
Avianca Logo
7:20 pm - 5:00 am
TYS
-
GUA
10h 40m1 stop
Avianca Logo
8:10 pm - 10:57 am
GUA
-
TYS
13h 47m2 stops
$588Avianca
Mon, Jan 26 - Fri, Jan 30

United Airlines flights from Knoxville to Guatemala City

Our best United Airlines deals on Knoxville to Guatemala City flight tickets
United Airlines
Feb 19
TYS9:10 amKnoxville McGhee Tyson
11h 29m
1 stop
GUA7:39 pmGuatemala City La Aurora
Mar 3
GUA2:10 amGuatemala City La Aurora
16h 45m
1 stop
TYS7:55 pmKnoxville McGhee Tyson
$526
Find similar
United Airlines
Mar 6
TYS9:00 amKnoxville McGhee Tyson
11h 39m
1 stop
GUA7:39 pmGuatemala City La Aurora
Mar 15
GUA6:00 amGuatemala City La Aurora
10h 10m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$1,283
Find similar
United Airlines
Mar 7
TYS11:40 amKnoxville McGhee Tyson
6h 45m
1 stop
GUA5:25 pmGuatemala City La Aurora
Mar 15
GUA6:00 amGuatemala City La Aurora
10h 10m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$1,383
Find similar

American Airlines flights from Knoxville to Guatemala City

Our best American Airlines deals on Knoxville to Guatemala City flight tickets
American Airlines
Feb 19
TYS6:00 amKnoxville McGhee Tyson
9h 54m
2 stops
GUA2:54 pmGuatemala City La Aurora
Mar 4
GUA7:00 amGuatemala City La Aurora
13h 28m
2 stops
TYS9:28 pmKnoxville McGhee Tyson
$530
Find similar
American Airlines
Jan 22
TYS8:09 amKnoxville McGhee Tyson
13h 56m
2 stops
GUA9:05 pmGuatemala City La Aurora
Feb 5
GUA7:00 amGuatemala City La Aurora
10h 46m
2 stops
TYS6:46 pmKnoxville McGhee Tyson
$560
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 1/22

1:39 pm-5:00 am

1 stop16h 21m

Guatemala City La Aurora

Thu 2/5

1:28 pm-1:40 pm

1 stop23h 12m

$363

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

9:32 pm-12:24 pm

1 stop15h 52m

Guatemala City La Aurora

Thu 3/5

1:29 pm-11:27 pm

1 stop8h 58m

$375

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

5:56 pm-11:20 am

2 stops42h 24m

Guatemala City La Aurora

Thu 3/5

1:29 pm-11:27 pm

1 stop8h 58m

$384

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 1/22

1:39 pm-5:00 am

1 stop16h 21m

Guatemala City La Aurora

Thu 2/5

1:28 pm-12:05 pm

2 stops21h 37m

$399

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

7:20 pm-5:00 am

1 stop10h 40m

Guatemala City La Aurora

Fri 1/30

7:10 pm-10:57 am

1 stop14h 47m

$452

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

9:10 am-7:39 pm

1 stop11h 29m

Guatemala City La Aurora

Tue 3/3

2:10 am-7:55 pm

1 stop16h 45m

$526

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

6:00 am-2:54 pm

2 stops9h 54m

Guatemala City La Aurora

Wed 3/4

7:00 am-9:28 pm

2 stops13h 28m

$530

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

7:20 pm-5:00 am

1 stop10h 40m

Guatemala City La Aurora

Fri 1/30

7:10 pm-10:57 am

1 stop14h 47m

$536

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 1/22

8:09 am-9:05 pm

2 stops13h 56m

Guatemala City La Aurora

Thu 2/5

7:00 am-6:46 pm

2 stops10h 46m

$560

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

7:20 pm-5:00 am

1 stop10h 40m

Guatemala City La Aurora

Fri 1/30

8:10 pm-10:57 am

2 stops13h 47m

$588

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guatemala City from

How to get the cheapest flight ticket from Knoxville to Guatemala City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guatemala City?

The cheapest day to depart from Knoxville to Guatemala City is on a Tuesday when prices can be found for as low as $485. On the other hand, Saturday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $740.

What is the cheapest time of day to depart on your flight to Guatemala City?

Our data shows that the cheapest Knoxville to Guatemala City flights are usually those with departure times in the afternoon. Our users have found flights to Guatemala City in the afternoon for as low as $550. Flights to Guatemala City are more costly in the morning, with an average ticket price of $630. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Guatemala City

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Guatemala City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Guatemala City (TYS to GUA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala City

Fastest flight time

6h 25m

Direct flights

None
The fastest flight from Knoxville to Guatemala City takes 6h 25m
There are no direct flights from Knoxville to Guatemala City. There are no popular flight routes from Knoxville to Guatemala City.
Search flight deals

  • How far is Knoxville McGhee Tyson to Guatemala City La Aurora by plane?

    Knoxville McGhee Tyson and Guatemala City La Aurora are 1527.7 mi apart from one another. Flights usually cover this in 6h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport.

  • What documentation or ID do you need to fly to Guatemala City La Aurora Airport?

    The travel and health documents required for your trip to Guatemala City La Aurora Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala City La Aurora Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Knoxville to Guatemala City?

Best airlines flying from Knoxville to Guatemala City

Compare and see reviews for airlines that fly from Knoxville to Guatemala City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,067 reviews
Search American Airlines flights
DeltaPriceFrom $504Free CancellationRating
7.9
8,018 reviews
Search Delta flights

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel
Quetzaltenango

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala City. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala City from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala City?

Once all potential Knoxville to Guatemala City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Guatemala City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guatemala City from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Find better results for your trip to Guatemala

Airports servicing Guatemala

Flores Santa Elena Airport