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Cheap flights from Knoxville to Guatemala City from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala City departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Guatemala City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:59 pm - 11:19 amTYS-GUA
21h 20m1 stop
Multiple Airlines Logo
12:20 pm - 9:49 pmGUA-TYS
8h 29m1 stop
$385Multiple Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
Multiple Airlines Logo
11:29 am - 1:50 pmTYS-GUA
27h 21m2 stops
Multiple Airlines Logo
1:29 pm - 8:33 amGUA-TYS
18h 04m1 stop
$387Multiple Airlines
Find Deal
Sun, Nov 30 - Sun, Dec 7
Multiple Airlines Logo
2:40 pm - 12:26 pmTYS-GUA
46h 46m2 stops
Multiple Airlines Logo
1:22 pm - 8:39 amGUA-TYS
18h 17m1 stop
$427Multiple Airlines
Find Deal
Mon, Jan 19 - Sat, Jan 31
Multiple Airlines Logo
9:53 am - 12:33 pmTYS-GUA
27h 40m1 stop
Multiple Airlines Logo
2:55 pm - 3:49 pmGUA-TYS
23h 54m1 stop
$430Multiple Airlines
Find Deal
Sat, Nov 22 - Sun, Nov 30
Delta Logo
5:30 am - 11:45 amTYS-GUA
8h 15m1 stop
Delta Logo
1:10 pm - 11:44 pmGUA-TYS
8h 34m1 stop
$532Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
Delta Logo
5:30 am - 11:45 amTYS-GUA
8h 15m1 stop
Delta Logo
1:10 pm - 11:44 pmGUA-TYS
8h 34m1 stop
$551Delta
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Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
7:00 am - 12:26 pmTYS-GUA
6h 26m1 stop
United Airlines Logo
1:05 am - 10:48 amGUA-TYS
8h 43m1 stop
$581United Airlines
Find Deal
Fri, Nov 28 - Thu, Dec 4
American Airlines Logo
5:49 am - 12:29 pmTYS-GUA
8h 40m1 stop
American Airlines Logo
3:15 pm - 3:19 pmGUA-TYS
22h 04m2 stops
$646American Airlines
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Tue, Mar 10 - Wed, Mar 11
American Airlines Logo
6:00 am - 2:44 pmTYS-GUA
9h 44m2 stops
American Airlines Logo
7:00 am - 8:56 pmGUA-TYS
12h 56m2 stops
$654American Airlines
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Mon, Jan 19 - Sat, Jan 31
United Airlines Logo
5:45 am - 9:25 pmTYS-GUA
16h 40m1 stop
United Airlines Logo
2:10 am - 1:49 pmGUA-TYS
10h 39m1 stop
$904United Airlines
Find Deal
Sun, Nov 30 - Sat, Dec 6

United Airlines flights from Knoxville to Guatemala City

Our best United Airlines deals on Knoxville to Guatemala City flight tickets
United Airlines
Nov 28
TYS7:00 amKnoxville McGhee Tyson
6h 26m
1 stop
GUA12:26 pmGuatemala City La Aurora
Dec 4
GUA1:05 amGuatemala City La Aurora
8h 43m
1 stop
TYS10:48 amKnoxville McGhee Tyson
$581
Find similar
United Airlines
Nov 30
TYS5:45 amKnoxville McGhee Tyson
16h 40m
1 stop
GUA9:25 pmGuatemala City La Aurora
Dec 6
GUA2:10 amGuatemala City La Aurora
10h 39m
1 stop
TYS1:49 pmKnoxville McGhee Tyson
$904
Find similar
United Airlines
Mar 10
TYS6:55 amKnoxville McGhee Tyson
13h 44m
1 stop
GUA6:39 pmGuatemala City La Aurora
Mar 10
GUA1:10 amGuatemala City La Aurora
10h 40m
1 stop
TYS1:50 pmKnoxville McGhee Tyson
$940
Find similar

American Airlines flights from Knoxville to Guatemala City

Our best American Airlines deals on Knoxville to Guatemala City flight tickets
American Airlines
Mar 10
TYS5:49 amKnoxville McGhee Tyson
8h 40m
1 stop
GUA12:29 pmGuatemala City La Aurora
Mar 11
GUA3:15 pmGuatemala City La Aurora
22h 04m
2 stops
TYS3:19 pmKnoxville McGhee Tyson
$646
Find similar
American Airlines
Jan 19
TYS6:00 amKnoxville McGhee Tyson
9h 44m
2 stops
GUA2:44 pmGuatemala City La Aurora
Jan 31
GUA7:00 amGuatemala City La Aurora
12h 56m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
$654
Find similar
American Airlines
Mar 10
TYS6:58 amKnoxville McGhee Tyson
8h 12m
2 stops
GUA1:10 pmGuatemala City La Aurora
Mar 11
GUA1:15 pmGuatemala City La Aurora
20h 06m
2 stops
TYS11:21 amKnoxville McGhee Tyson
$726
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 11/28

2:59 pm-11:19 am

1 stop21h 20m

Guatemala City La Aurora

Fri 12/5

12:20 pm-9:49 pm

1 stop8h 29m

$385

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 11/30

11:29 am-1:50 pm

2 stops27h 21m

Guatemala City La Aurora

Sun 12/7

1:29 pm-8:33 am

1 stop18h 04m

$387

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/19

2:40 pm-12:26 pm

2 stops46h 46m

Guatemala City La Aurora

Sat 1/31

1:22 pm-8:39 am

1 stop18h 17m

$427

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 11/22

9:53 am-12:33 pm

1 stop27h 40m

Guatemala City La Aurora

Sun 11/30

2:55 pm-3:49 pm

1 stop23h 54m

$430

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

5:30 am-11:45 am

1 stop8h 15m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:44 pm

1 stop8h 34m

$532

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

5:30 am-11:45 am

1 stop8h 15m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:44 pm

1 stop8h 34m

$551

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 11/28

7:00 am-12:26 pm

1 stop6h 26m

Guatemala City La Aurora

Thu 12/4

1:05 am-10:48 am

1 stop8h 43m

$581

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

5:49 am-12:29 pm

1 stop8h 40m

Guatemala City La Aurora

Wed 3/11

3:15 pm-3:19 pm

2 stops22h 04m

$646

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/19

6:00 am-2:44 pm

2 stops9h 44m

Guatemala City La Aurora

Sat 1/31

7:00 am-8:56 pm

2 stops12h 56m

$654

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 11/30

5:45 am-9:25 pm

1 stop16h 40m

Guatemala City La Aurora

Sat 12/6

2:10 am-1:49 pm

1 stop10h 39m

$904

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Guatemala City from

How to get the cheapest flight ticket from Knoxville to Guatemala City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Guatemala City?

What is the cheapest day to depart on your flight to Guatemala City?

The cheapest day to depart from Knoxville to Guatemala City is on a Tuesday when prices can be found for as low as $485. On the other hand, Saturday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $740.

What is the cheapest time of day to depart on your flight to Guatemala City?

Our data shows that the cheapest Knoxville to Guatemala City flights are usually those with departure times in the afternoon. Our users have found flights to Guatemala City in the afternoon for as low as $550. Flights to Guatemala City are more costly in the morning, with an average ticket price of $630. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Guatemala City

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Guatemala City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Guatemala City (TYS to GUA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala City

Direct flights

None
There are no direct flights from Knoxville to Guatemala City. There are no popular flight routes from Knoxville to Guatemala City.
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  • How far is Knoxville McGhee Tyson to Guatemala City La Aurora by plane?

    Knoxville McGhee Tyson and Guatemala City La Aurora are 1527.7 mi apart from one another. Flights usually cover this in 6h 26m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala City La Aurora Airport.

  • What documentation or ID do you need to fly to Guatemala City La Aurora Airport?

    The travel and health documents required for your trip to Guatemala City La Aurora Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala City La Aurora Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Knoxville to Guatemala City?

Best airlines flying from Knoxville to Guatemala City

Compare and see reviews for airlines that fly from Knoxville to Guatemala City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $492Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights
DeltaPriceFrom $504Free CancellationRating
7.9
7,977 reviews
Search Delta flights

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel
Quetzaltenango

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala City. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala City from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala City?

Once all potential Knoxville to Guatemala City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Guatemala City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guatemala City from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Find better results for your trip to Guatemala

Airports servicing Guatemala

Flores Santa Elena Airport