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Cheap flights from Knoxville to Florence from $548

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Florence departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
KLM Logo
12:49 pm - 11:20 amTYS-FLR
16h 31m2 stops
KLM Logo
6:40 am - 6:52 pmFLR-TYS
18h 12m2 stops
$548KLM
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Mon, Dec 1 - Mon, Dec 15
United Airlines Logo
1:52 pm - 10:00 pmTYS-FLR
26h 08m2 stops
United Airlines Logo
6:30 am - 7:29 pmFLR-TYS
18h 59m2 stops
$634United Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
United Airlines Logo
7:25 pm - 4:30 pmTYS-FLR
39h 05m2 stops
United Airlines Logo
2:15 pm - 10:48 amFLR-TYS
25h 33m2 stops
$653United Airlines
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Sat, Mar 7 - Sun, Mar 15
Lufthansa Logo
7:25 pm - 8:40 pmTYS-FLR
20h 15m2 stops
Lufthansa Logo
10:20 am - 11:59 pmFLR-TYS
19h 39m2 stops
$743Lufthansa
Find Deal
Wed, Mar 25 - Fri, Apr 3
United Airlines Logo
5:45 am - 4:30 pmTYS-FLR
29h 45m2 stops
United Airlines Logo
9:35 am - 11:59 pmFLR-TYS
20h 24m2 stops
$800United Airlines
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Fri, Oct 31 - Sat, Nov 8
Multiple Airlines Logo
8:30 am - 6:30 pmTYS-FLR
29h 00m2 stops
Multiple Airlines Logo
9:55 pm - 9:14 pmFLR-TYS
29h 19m3 stops
$1,242Multiple Airlines
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Wed, Mar 25 - Fri, Apr 3
Air Canada Logo
9:40 am - 9:40 amTYS-FLR
18h 00m3 stops
Air Canada Logo
2:15 pm - 2:56 pmFLR-TYS
29h 41m3 stops
$1,480Air Canada
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Sat, Mar 7 - Sun, Mar 15
Air Canada Logo
9:50 am - 1:35 pmTYS-FLR
21h 45m3 stops
Air Canada Logo
6:30 am - 7:29 pmFLR-TYS
18h 59m3 stops
$1,612Air Canada
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Mon, Dec 1 - Mon, Dec 15
Lufthansa Logo
7:25 pm - 4:30 pmTYS-FLR
16h 05m2 stops
Lufthansa Logo
1:35 pm - 11:59 pmFLR-TYS
16h 24m2 stops
$1,746Lufthansa
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Wed, Mar 25 - Fri, Apr 3
British Airways Logo
8:02 am - 2:05 pmTYS-FLR
25h 03m2 stops
British Airways Logo
7:05 am - 8:39 pmFLR-TYS
19h 34m2 stops
$3,490British Airways
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Wed, Mar 25 - Fri, Apr 3

United Airlines flights from Knoxville to Florence

Our best United Airlines deals on Knoxville to Florence flight tickets
United Airlines
Dec 2
TYS1:52 pmKnoxville McGhee Tyson
26h 08m
2 stops
FLR10:00 pmFlorence Peretola
Dec 9
FLR6:30 amFlorence Peretola
18h 59m
2 stops
TYS7:29 pmKnoxville McGhee Tyson
$634
Find similar
United Airlines
Mar 7
TYS7:25 pmKnoxville McGhee Tyson
39h 05m
2 stops
FLR4:30 pmFlorence Peretola
Mar 15
FLR2:15 pmFlorence Peretola
25h 33m
2 stops
TYS10:48 amKnoxville McGhee Tyson
$653
Find similar
United Airlines
Oct 31
TYS5:45 amKnoxville McGhee Tyson
29h 45m
2 stops
FLR4:30 pmFlorence Peretola
Nov 8
FLR9:35 amFlorence Peretola
20h 24m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$800
Find similar

Lufthansa flights from Knoxville to Florence

Our best Lufthansa deals on Knoxville to Florence flight tickets
Lufthansa
Mar 25
TYS7:25 pmKnoxville McGhee Tyson
20h 15m
2 stops
FLR8:40 pmFlorence Peretola
Apr 3
FLR10:20 amFlorence Peretola
19h 39m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$743
Find similar
Lufthansa
Mar 25
TYS7:25 pmKnoxville McGhee Tyson
16h 05m
2 stops
FLR4:30 pmFlorence Peretola
Apr 3
FLR1:35 pmFlorence Peretola
16h 24m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$1,746
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Mon 12/1

12:49 pm-11:20 am

2 stops16h 31m

Florence Peretola

Mon 12/15

6:40 am-6:52 pm

2 stops18h 12m

$548

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 12/2

1:52 pm-10:00 pm

2 stops26h 08m

Florence Peretola

Tue 12/9

6:30 am-7:29 pm

2 stops18h 59m

$634

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 3/7

7:25 pm-4:30 pm

2 stops39h 05m

Florence Peretola

Sun 3/15

2:15 pm-10:48 am

2 stops25h 33m

$653

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/25

7:25 pm-8:40 pm

2 stops20h 15m

Florence Peretola

Fri 4/3

10:20 am-11:59 pm

2 stops19h 39m

$743

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 10/31

5:45 am-4:30 pm

2 stops29h 45m

Florence Peretola

Sat 11/8

9:35 am-11:59 pm

2 stops20h 24m

$800

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/25

8:30 am-6:30 pm

2 stops29h 00m

Florence Peretola

Fri 4/3

9:55 pm-9:14 pm

3 stops29h 19m

$1,242

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 3/7

9:40 am-9:40 am

3 stops18h 00m

Florence Peretola

Sun 3/15

2:15 pm-2:56 pm

3 stops29h 41m

$1,480

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Mon 12/1

9:50 am-1:35 pm

3 stops21h 45m

Florence Peretola

Mon 12/15

6:30 am-7:29 pm

3 stops18h 59m

$1,612

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/25

7:25 pm-4:30 pm

2 stops16h 05m

Florence Peretola

Fri 4/3

1:35 pm-11:59 pm

2 stops16h 24m

$1,746

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/25

8:02 am-2:05 pm

2 stops25h 03m

Florence Peretola

Fri 4/3

7:05 am-8:39 pm

2 stops19h 34m

$3,490

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Knoxville to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence?

On average, the least expensive day to fly to Florence from Knoxville is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $930. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Florence on Saturday is $1,815.

What is the cheapest time of day to depart on your flight to Florence?

Our data shows that the cheapest Knoxville to Florence flights are usually those with departure times in the afternoon. Our users have found flights to Florence in the afternoon for as low as $1,130. Flights to Florence are more costly in the evening, with an average ticket price of $1,671. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Florence (TYS to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florence

Direct flights

None
There are no direct flights from Knoxville to Florence. There are no popular flight routes from Knoxville to Florence.
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  • How far is Knoxville McGhee Tyson to Florence Peretola by plane?

    Florence Peretola is 4784.7 mi away from Knoxville McGhee Tyson. Flights usually cover this in 16h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The travel and health documents you'll need for your trip to Florence Peretola Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Peretola Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Florence?

Best airlines flying from Knoxville to Florence

Compare and see reviews for airlines that fly from Knoxville to Florence with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $649Free CancellationRating
6.8
7,506 reviews
Search Lufthansa flights
DeltaPriceFrom $832Free CancellationRating
7.9
7,977 reviews
Search Delta flights
United AirlinesPriceFrom $894Free CancellationRating
7.4
8,990 reviews
Search United Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Siena
Prato
San Gimignano
Montecatini Terme
Arezzo
Pistoia
Colle di Val d'Elsa
Fiesole
Poggibonsi
Impruneta
Greve in Chianti
Monteriggioni
Volterra

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Florence with flexible booking policies on momondo?

All flight searches from Knoxville to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Florence.

I’m not ready to book a flight from Knoxville to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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