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Cheap flights from Knoxville to Florence from $460

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Florence departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:15 am - 4:20 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
25h 05m2 stops Houston George Bush Intcntl Munich Franz Josef Strauss
United Airlines Logo
6:30 am - 7:34 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
19h 04m2 stops Frankfurt am Main Houston George Bush Intcntl
$783United Airlines
Sun, Dec 6 - Tue, Dec 8
United Airlines Logo
5:39 pm - 4:20 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
40h 41m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
United Airlines Logo
6:30 am - 11:19 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
22h 49m2 stops Frankfurt am Main Houston George Bush Intcntl
$788United Airlines
Mon, Dec 7 - Thu, Dec 10
United Airlines Logo
9:45 am - 4:35 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
24h 50m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
United Airlines Logo
8:15 am - 4:35 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
38h 20m2 stops Munich Franz Josef Strauss Newark
$829United Airlines
Wed, Oct 21 - Wed, Nov 4
United Airlines Logo
7:25 pm - 4:35 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
15h 10m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
United Airlines Logo
8:15 am - 10:49 amFLR  Florence Peretola-TYS Knoxville McGhee Tyson
56h 34m2 stops Munich Franz Josef Strauss Newark
$835United Airlines
Wed, Oct 21 - Wed, Nov 4
Air Canada Logo
9:45 am - 9:40 amTYS  Knoxville McGhee Tyson-FLR Florence Peretola
17h 55m3 stops Washington, D.C. Dulles Intl Montreal Pierre Elliott Trudeau Intl Frankfurt am Main
Air Canada Logo
6:30 am - 11:59 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
23h 29m3 stops Frankfurt am Main Montreal Pierre Elliott Trudeau Intl Washington, D.C. Dulles Intl
$914Air Canada
Wed, Oct 21 - Wed, Nov 4
Air Canada Logo
9:45 am - 9:40 amTYS  Knoxville McGhee Tyson-FLR Florence Peretola
17h 55m3 stops Washington, D.C. Dulles Intl Montreal Pierre Elliott Trudeau Intl Frankfurt am Main
Air Canada Logo
6:30 am - 11:59 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
23h 29m3 stops Frankfurt am Main Toronto Pearson Intl Washington, D.C. Dulles Intl
$919Air Canada
Wed, Oct 21 - Wed, Nov 4
Lufthansa Logo
9:45 am - 4:35 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
24h 50m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
5:15 pm - 11:59 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
36h 44m2 stops Munich Franz Josef Strauss Washington, D.C. Dulles Intl
$973Lufthansa
Wed, Sep 30 - Tue, Oct 6
United Airlines Logo
9:45 am - 4:35 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
24h 50m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
United Airlines Logo
1:40 pm - 9:45 amFLR  Florence Peretola-TYS Knoxville McGhee Tyson
26h 05m2 stops Frankfurt am Main Chicago O'Hare Intl
$974United Airlines
Wed, Sep 30 - Tue, Oct 6
Lufthansa Logo
7:20 pm - 4:35 pmTYS  Knoxville McGhee Tyson-FLR Florence Peretola
15h 15m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
10:20 am - 11:59 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
19h 39m2 stops Frankfurt am Main Washington, D.C. Dulles Intl
$1,012Lufthansa
Thu, Sep 10 - Wed, Sep 16
Air Canada Logo
9:45 am - 9:40 amTYS  Knoxville McGhee Tyson-FLR Florence Peretola
17h 55m3 stops Washington, D.C. Dulles Intl Montreal Pierre Elliott Trudeau Intl Frankfurt am Main
Air Canada Logo
6:30 am - 7:36 pmFLR  Florence Peretola-TYS Knoxville McGhee Tyson
19h 06m3 stops Frankfurt am Main Montreal Pierre Elliott Trudeau Intl Washington, D.C. Dulles Intl
$1,024Air Canada
Wed, Oct 21 - Wed, Nov 4

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Lufthansa flights from Knoxville to Florence

Our best Lufthansa deals on Knoxville to Florence flight tickets
Lufthansa
Sep 30
TYS7:25 pmKnoxville McGhee Tyson
18h 50m
2 stops
FLR8:15 pmFlorence Peretola
Oct 6
FLR5:15 pmFlorence Peretola
36h 44m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$973
Lufthansa
Sep 10
TYS7:20 pmKnoxville McGhee Tyson
15h 15m
2 stops
FLR4:35 pmFlorence Peretola
Sep 16
FLR10:20 amFlorence Peretola
19h 39m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$1,012
Lufthansa
Oct 26
TYS7:35 pmKnoxville McGhee Tyson
19h 40m
2 stops
FLR8:15 pmFlorence Peretola
Oct 31
FLR5:00 pmFlorence Peretola
57h 54m
2 stops
TYS9:54 pmKnoxville McGhee Tyson
$1,314

Air Canada flights from Knoxville to Florence

Our best Air Canada deals on Knoxville to Florence flight tickets
Air Canada
Oct 21
TYS9:45 amKnoxville McGhee Tyson
17h 55m
3 stops
FLR9:40 amFlorence Peretola
Nov 4
FLR6:30 amFlorence Peretola
23h 29m
3 stops
TYS11:59 pmKnoxville McGhee Tyson
$914
Air Canada
Oct 21
TYS9:45 amKnoxville McGhee Tyson
17h 55m
3 stops
FLR9:40 amFlorence Peretola
Nov 4
FLR6:30 amFlorence Peretola
23h 29m
3 stops
TYS11:59 pmKnoxville McGhee Tyson
$919
Air Canada
Oct 21
TYS9:45 amKnoxville McGhee Tyson
17h 55m
3 stops
FLR9:40 amFlorence Peretola
Nov 4
FLR6:30 amFlorence Peretola
19h 06m
3 stops
TYS7:36 pmKnoxville McGhee Tyson
$1,024

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Sun 12/6

9:15 am-4:20 pm

2 stops25h 05m

Florence Peretola

Tue 12/8

6:30 am-7:34 pm

2 stops19h 04m

$783

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Mon 12/7

5:39 pm-4:20 pm

2 stops40h 41m

Florence Peretola

Thu 12/10

6:30 am-11:19 pm

2 stops22h 49m

$788

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-4:35 pm

2 stops24h 50m

Florence Peretola

Wed 11/4

8:15 am-4:35 pm

2 stops38h 20m

$829

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

7:25 pm-4:35 pm

2 stops15h 10m

Florence Peretola

Wed 11/4

8:15 am-10:49 am

2 stops56h 34m

$835

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-9:40 am

3 stops17h 55m

Florence Peretola

Wed 11/4

6:30 am-11:59 pm

3 stops23h 29m

$914

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-9:40 am

3 stops17h 55m

Florence Peretola

Wed 11/4

6:30 am-11:59 pm

3 stops23h 29m

$919

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 9/30

9:45 am-4:35 pm

2 stops24h 50m

Florence Peretola

Tue 10/6

5:15 pm-11:59 pm

2 stops36h 44m

$973

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 9/30

9:45 am-4:35 pm

2 stops24h 50m

Florence Peretola

Tue 10/6

1:40 pm-9:45 am

2 stops26h 05m

$974
Quickest round-trip

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Thu 9/10

7:20 pm-4:35 pm

2 stops15h 15m

Florence Peretola

Wed 9/16

10:20 am-11:59 pm

2 stops19h 39m

$1,012

KnoxvilleFlorence

TYS Knoxville McGhee Tyson - FLR Florence Peretola

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-9:40 am

3 stops17h 55m

Florence Peretola

Wed 11/4

6:30 am-7:36 pm

3 stops19h 06m

$1,024

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florence?

If you aren’t able to travel during the month of December, then book flights to Florence from Knoxville during February instead. Flights to Florence in February, while not as cheap as those in December, still average around $0.

When to book flights from Knoxville to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Florence (TYS to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florence

Fastest flight time

14h 12m

Direct flights

None
The fastest flight from Knoxville to Florence takes 14h 12m
There are no direct flights from Knoxville to Florence. There are no popular flight routes from Knoxville to Florence.
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Frequently asked questions about flying from Knoxville to Florence

  • How far is Knoxville McGhee Tyson to Florence Peretola by plane?

    Florence Peretola is 4784.7 mi away from Knoxville McGhee Tyson. Flights usually cover this in 14h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The travel and health documents you'll need for your trip to Florence Peretola Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Peretola Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Florence?

Best airlines flying from Knoxville to Florence

Compare and see reviews for airlines that fly from Knoxville to Florence with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $759Free CancellationRating
6.8
8,182 reviews
Search Lufthansa flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Prato
Siena
San Gimignano
Fiesole
Montecatini Terme
Pistoia
Arezzo
Colle di Val d'Elsa
Monteriggioni
Greve in Chianti
Impruneta
Volterra
Poggibonsi

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Florence with flexible booking policies on momondo?

All flight searches from Knoxville to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Florence.

I’m not ready to book a flight from Knoxville to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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