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Cheap flights from Knoxville to Florence from $350

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Florence departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:25 pm - 4:35 pm
TYS
-
FLR
15h 10m
2 stops
United Airlines Logo
2:20 pm - 5:02 pm
FLR
-
TYS
32h 42m
2 stops
$801United Airlines
Wed, Oct 21 - Wed, Nov 4
United Airlines Logo
1:35 pm - 4:35 pm
TYS
-
FLR
21h 00m
2 stops
United Airlines Logo
2:20 pm - 11:56 pm
FLR
-
TYS
39h 36m
2 stops
$802United Airlines
Wed, Oct 21 - Wed, Nov 4
United Airlines Logo
9:45 am - 11:00 am
TYS
-
FLR
19h 15m
2 stops
United Airlines Logo
2:20 pm - 8:44 pm
FLR
-
TYS
36h 24m
2 stops
$803United Airlines
Wed, Oct 21 - Wed, Nov 4
United Airlines Logo
9:45 am - 4:35 pm
TYS
-
FLR
24h 50m
2 stops
United Airlines Logo
2:20 pm - 11:56 pm
FLR
-
TYS
39h 36m
2 stops
$853United Airlines
Thu, Oct 22 - Wed, Nov 4
Delta Logo
3:59 pm - 2:25 pm
TYS
-
FLR
16h 26m
2 stops
Delta Logo
6:30 am - 11:01 pm
FLR
-
TYS
22h 31m
2 stops
$900Delta
Wed, Jul 22 - Wed, Jul 29
United Airlines Logo
5:45 am - 4:35 pm
TYS
-
FLR
28h 50m
2 stops
United Airlines Logo
6:30 am - 7:34 pm
FLR
-
TYS
19h 04m
2 stops
$916United Airlines
Thu, Aug 20 - Sat, Dec 5
Multiple Airlines Logo
1:00 pm - 4:35 pm
TYS
-
FLR
21h 35m
2 stops
Multiple Airlines Logo
2:20 pm - 9:59 am
FLR
-
TYS
25h 39m
2 stops
$917Multiple Airlines
Thu, Aug 20 - Sat, Dec 5
Delta Logo
6:13 pm - 7:00 pm
TYS
-
FLR
18h 47m
2 stops
Delta Logo
6:40 am - 11:55 pm
FLR
-
TYS
23h 15m
2 stops
$926Delta
Wed, Sep 23 - Wed, Sep 30
United Airlines Logo
7:20 pm - 4:35 pm
TYS
-
FLR
15h 15m
2 stops
United Airlines Logo
6:30 am - 11:59 pm
FLR
-
TYS
23h 29m
2 stops
$945United Airlines
Wed, Sep 23 - Wed, Sep 30
Lufthansa Logo
6:02 pm - 8:15 pm
TYS
-
FLR
20h 13m
2 stops
Lufthansa Logo
6:30 am - 10:49 pm
FLR
-
TYS
22h 19m
2 stops
$954Lufthansa
Sun, Sep 6 - Wed, Sep 16

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United Airlines flights from Knoxville to Florence

Our best United Airlines deals on Knoxville to Florence flight tickets
United Airlines
Oct 21
TYS7:25 pmKnoxville McGhee Tyson
15h 10m
2 stops
FLR4:35 pmFlorence Peretola
Nov 4
FLR2:20 pmFlorence Peretola
32h 42m
2 stops
TYS5:02 pmKnoxville McGhee Tyson
$801
United Airlines
Oct 21
TYS1:35 pmKnoxville McGhee Tyson
21h 00m
2 stops
FLR4:35 pmFlorence Peretola
Nov 4
FLR2:20 pmFlorence Peretola
39h 36m
2 stops
TYS11:56 pmKnoxville McGhee Tyson
$802
United Airlines
Oct 21
TYS9:45 amKnoxville McGhee Tyson
19h 15m
2 stops
FLR11:00 amFlorence Peretola
Nov 4
FLR2:20 pmFlorence Peretola
36h 24m
2 stops
TYS8:44 pmKnoxville McGhee Tyson
$803

Lufthansa flights from Knoxville to Florence

Our best Lufthansa deals on Knoxville to Florence flight tickets
Lufthansa
Sep 6
TYS6:02 pmKnoxville McGhee Tyson
20h 13m
2 stops
FLR8:15 pmFlorence Peretola
Sep 16
FLR6:30 amFlorence Peretola
22h 19m
2 stops
TYS10:49 pmKnoxville McGhee Tyson
$954
Lufthansa
Sep 3
TYS7:20 pmKnoxville McGhee Tyson
18h 55m
2 stops
FLR8:15 pmFlorence Peretola
Sep 19
FLR5:15 pmFlorence Peretola
35h 34m
2 stops
TYS10:49 pmKnoxville McGhee Tyson
$1,091
Lufthansa
Sep 3
TYS7:20 pmKnoxville McGhee Tyson
18h 55m
2 stops
FLR8:15 pmFlorence Peretola
Sep 19
FLR5:15 pmFlorence Peretola
35h 34m
2 stops
TYS10:49 pmKnoxville McGhee Tyson
$1,093

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

7:25 pm-4:35 pm

2 stops15h 10m

Florence Peretola

Wed 11/4

2:20 pm-5:02 pm

2 stops32h 42m

$801

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

1:35 pm-4:35 pm

2 stops21h 00m

Florence Peretola

Wed 11/4

2:20 pm-11:56 pm

2 stops39h 36m

$802

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-11:00 am

2 stops19h 15m

Florence Peretola

Wed 11/4

2:20 pm-8:44 pm

2 stops36h 24m

$803

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 10/22

9:45 am-4:35 pm

2 stops24h 50m

Florence Peretola

Wed 11/4

2:20 pm-11:56 pm

2 stops39h 36m

$853

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 7/22

3:59 pm-2:25 pm

2 stops16h 26m

Florence Peretola

Wed 7/29

6:30 am-11:01 pm

2 stops22h 31m

$900

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 8/20

5:45 am-4:35 pm

2 stops28h 50m

Florence Peretola

Sat 12/5

6:30 am-7:34 pm

2 stops19h 04m

$916

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 8/20

1:00 pm-4:35 pm

2 stops21h 35m

Florence Peretola

Sat 12/5

2:20 pm-9:59 am

2 stops25h 39m

$917

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 9/23

6:13 pm-7:00 pm

2 stops18h 47m

Florence Peretola

Wed 9/30

6:40 am-11:55 pm

2 stops23h 15m

$926
Quickest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 9/23

7:20 pm-4:35 pm

2 stops15h 15m

Florence Peretola

Wed 9/30

6:30 am-11:59 pm

2 stops23h 29m

$945

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sun 9/6

6:02 pm-8:15 pm

2 stops20h 13m

Florence Peretola

Wed 9/16

6:30 am-10:49 pm

2 stops22h 19m

$954

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Knoxville to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Florence Peretola?

Lufthansa, Air Canada, and Air France are the most popular carriers operating from Knoxville McGhee Tyson to Florence Peretola

When to book flights from Knoxville to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Florence (TYS to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florence

Fastest flight time

15h 10m

Direct flights

None
The fastest flight from Knoxville to Florence takes 15h 10m
There are no direct flights from Knoxville to Florence. There are no popular flight routes from Knoxville to Florence.
Search flight deals

Frequently asked questions about flying from Knoxville to Florence

  • How far is Knoxville McGhee Tyson to Florence Peretola by plane?

    Florence Peretola is 4784.7 mi away from Knoxville McGhee Tyson. Flights usually cover this in 15h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The travel and health documents you'll need for your trip to Florence Peretola Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Peretola Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Florence?

Best airlines flying from Knoxville to Florence

Compare and see reviews for airlines that fly from Knoxville to Florence with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $564Free CancellationRating
7.4
9,896 reviews
Search United Airlines flights
LufthansaPriceFrom $649Free CancellationRating
6.8
8,103 reviews
Search Lufthansa flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Prato
Siena
San Gimignano
Montecatini Terme
Fiesole
Pistoia
Arezzo
Colle di Val d'Elsa
Monteriggioni
Greve in Chianti
Impruneta
Volterra
Poggibonsi

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Florence with flexible booking policies on momondo?

All flight searches from Knoxville to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Florence.

I’m not ready to book a flight from Knoxville to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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