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Cheap flights from Knoxville to Florence from $490

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Florence departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:30 am - 2:25 pm
TYS
-
FLR
24h 55m2 stops
Delta Logo
12:20 pm - 8:47 pm
FLR
-
TYS
38h 27m2 stops
$490Delta
Thu, Jan 15 - Mon, Jan 19
United Airlines Logo
2:25 pm - 12:35 pm
TYS
-
FLR
16h 10m2 stops
United Airlines Logo
6:30 am - 1:24 pm
FLR
-
TYS
36h 54m2 stops
$498United Airlines
Fri, Feb 6 - Tue, Feb 10
United Airlines Logo
11:07 am - 12:35 pm
TYS
-
FLR
19h 28m2 stops
United Airlines Logo
6:30 am - 8:52 pm
FLR
-
TYS
20h 22m2 stops
$500United Airlines
Fri, Feb 6 - Tue, Feb 10
Brussels Airlines Logo
2:25 pm - 10:40 pm
TYS
-
FLR
26h 15m2 stops
Brussels Airlines Logo
3:00 pm - 7:27 pm
FLR
-
TYS
34h 27m3 stops
$725Brussels Airlines
Thu, Jan 15 - Mon, Jan 19
Brussels Airlines Logo
2:25 pm - 10:55 am
TYS
-
FLR
38h 30m3 stops
Brussels Airlines Logo
3:00 pm - 7:27 pm
FLR
-
TYS
34h 27m3 stops
$821Brussels Airlines
Thu, Jan 15 - Mon, Jan 19
Multiple Airlines Logo
1:39 pm - 10:55 pm
TYS
-
FLR
27h 16m3 stops
Multiple Airlines Logo
6:30 am - 12:05 pm
FLR
-
TYS
35h 35m3 stops
$841Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
1:39 pm - 6:05 pm
TYS
-
FLR
22h 26m3 stops
Multiple Airlines Logo
12:20 pm - 12:05 pm
FLR
-
TYS
29h 45m2 stops
$1,172Multiple Airlines
Sun, Jan 18 - Sun, Jan 25

United Airlines flights from Knoxville to Florence

Our best United Airlines deals on Knoxville to Florence flight tickets
United Airlines
Feb 6
TYS2:25 pmKnoxville McGhee Tyson
16h 10m
2 stops
FLR12:35 pmFlorence Peretola
Feb 10
FLR6:30 amFlorence Peretola
36h 54m
2 stops
TYS1:24 pmKnoxville McGhee Tyson
$498
Find similar
United Airlines
Feb 6
TYS11:07 amKnoxville McGhee Tyson
19h 28m
2 stops
FLR12:35 pmFlorence Peretola
Feb 10
FLR6:30 amFlorence Peretola
20h 22m
2 stops
TYS8:52 pmKnoxville McGhee Tyson
$500
Find similar

Brussels Airlines flights from Knoxville to Florence

Our best Brussels Airlines deals on Knoxville to Florence flight tickets
Brussels Airlines
Jan 15
TYS2:25 pmKnoxville McGhee Tyson
26h 15m
2 stops
FLR10:40 pmFlorence Peretola
Jan 19
FLR3:00 pmFlorence Peretola
34h 27m
3 stops
TYS7:27 pmKnoxville McGhee Tyson
$725
Find similar
Brussels Airlines
Jan 15
TYS2:25 pmKnoxville McGhee Tyson
38h 30m
3 stops
FLR10:55 amFlorence Peretola
Jan 19
FLR3:00 pmFlorence Peretola
34h 27m
3 stops
TYS7:27 pmKnoxville McGhee Tyson
$821
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 6, 2025.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 1/15

7:30 am-2:25 pm

2 stops24h 55m

Florence Peretola

Mon 1/19

12:20 pm-8:47 pm

2 stops38h 27m

$490

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 2/6

2:25 pm-12:35 pm

2 stops16h 10m

Florence Peretola

Tue 2/10

6:30 am-1:24 pm

2 stops36h 54m

$498

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 2/6

11:07 am-12:35 pm

2 stops19h 28m

Florence Peretola

Tue 2/10

6:30 am-8:52 pm

2 stops20h 22m

$500

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 1/15

2:25 pm-10:40 pm

2 stops26h 15m

Florence Peretola

Mon 1/19

3:00 pm-7:27 pm

3 stops34h 27m

$725

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 1/15

2:25 pm-10:55 am

3 stops38h 30m

Florence Peretola

Mon 1/19

3:00 pm-7:27 pm

3 stops34h 27m

$821

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-10:55 pm

3 stops27h 16m

Florence Peretola

Sun 1/25

6:30 am-12:05 pm

3 stops35h 35m

$841

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-6:05 pm

3 stops22h 26m

Florence Peretola

Sun 1/25

12:20 pm-12:05 pm

2 stops29h 45m

$1,172

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Knoxville to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence?

On average, the least expensive day to fly to Florence from Knoxville is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $930. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Florence on Saturday is $1,815.

What is the cheapest time of day to depart on your flight to Florence?

Our data shows that the cheapest Knoxville to Florence flights are usually those with departure times in the afternoon. Our users have found flights to Florence in the afternoon for as low as $1,130. Flights to Florence are more costly in the evening, with an average ticket price of $1,671. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Florence (TYS to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florence

Fastest flight time

19h 28m

Direct flights

None
The fastest flight from Knoxville to Florence takes 19h 28m
There are no direct flights from Knoxville to Florence. There are no popular flight routes from Knoxville to Florence.
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  • How far is Knoxville McGhee Tyson to Florence Peretola by plane?

    Florence Peretola is 4784.7 mi away from Knoxville McGhee Tyson. Flights usually cover this in 16h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florence Peretola Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The travel and health documents you'll need for your trip to Florence Peretola Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Peretola Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Florence?

Best airlines flying from Knoxville to Florence

Compare and see reviews for airlines that fly from Knoxville to Florence with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $649Free CancellationRating
6.8
7,616 reviews
Search Lufthansa flights
United AirlinesPriceFrom $814Free CancellationRating
7.4
9,065 reviews
Search United Airlines flights
DeltaPriceFrom $832Free CancellationRating
7.9
8,009 reviews
Search Delta flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Siena
Prato
San Gimignano
Montecatini Terme
Arezzo
Pistoia
Colle di Val d'Elsa
Fiesole
Impruneta
Greve in Chianti
Monteriggioni
Volterra

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Florence with flexible booking policies on momondo?

All flight searches from Knoxville to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Florence.

I’m not ready to book a flight from Knoxville to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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