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Cheap flights from Columbus Airport to Panama from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Panama departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to Panama

Cheap round-trip flights

United Airlines Logo
6:15 am - 1:50 pmCMH-PTY
8h 35m1 stop
United Airlines Logo
3:30 pm - 10:59 amPTY-CMH
18h 29m1 stop
$413United Airlines
Find Deal
mié., oct. 8 - lun., oct. 20
United Airlines Logo
6:15 am - 2:14 pmCMH-PTY
8h 59m1 stop
United Airlines Logo
3:30 pm - 9:58 amPTY-CMH
17h 28m2 stops
$418United Airlines
Find Deal
mié., oct. 8 - lun., oct. 20
United Airlines Logo
6:30 am - 7:38 pmCMH-PTY
13h 08m1 stop
United Airlines Logo
8:55 am - 10:12 pmPTY-CMH
13h 17m1 stop
$430United Airlines
Find Deal
jue., nov. 13 - dom., nov. 16
United Airlines Logo
8:45 am - 6:37 pmCMH-PTY
10h 52m2 stops
United Airlines Logo
3:41 pm - 1:21 pmPTY-CMH
20h 40m2 stops
$435United Airlines
Find Deal
sáb., oct. 25 - lun., oct. 27
American Airlines Logo
3:57 pm - 1:10 pmCMH-PTY
21h 13m2 stops
American Airlines Logo
2:45 pm - 12:32 amPTY-CMH
9h 47m1 stop
$457American Airlines
Find Deal
dom., feb. 1 - dom., feb. 8
Delta Logo
6:00 am - 2:12 pmCMH-PTY
8h 12m1 stop
Delta Logo
3:37 pm - 12:18 amPTY-CMH
8h 41m1 stop
$461Delta
Find Deal
lun., nov. 24 - jue., nov. 27
American Airlines Logo
12:11 pm - 1:10 pmCMH-PTY
24h 59m1 stop
American Airlines Logo
2:45 pm - 12:32 amPTY-CMH
9h 47m1 stop
$463American Airlines
Find Deal
dom., feb. 1 - dom., feb. 8
Logo
5:00 am - 9:10 pmCMH-PTY
17h 10m2 stops
Logo
2:55 am - 5:16 pmPTY-CMH
13h 21m2 stops
$522
Find Deal
vie., oct. 24 - jue., oct. 30
Logo
6:45 am - 1:00 amCMH-PTY
18h 15m2 stops
Logo
2:55 am - 9:12 pmPTY-CMH
18h 17m2 stops
$543
Find Deal
mar., nov. 11 - lun., nov. 17
Avianca Logo
7:50 pm - 7:25 pmCMH-PTY
23h 35m3 stops
Avianca Logo
1:45 pm - 9:49 amPTY-CMH
20h 04m3 stops
$895Avianca
Find Deal
mar., nov. 11 - mar., nov. 18

United Airlines flights from Columbus Airport to Panama

Our best United Airlines deals on Columbus Airport to Panama flight tickets
United Airlines
Oct 8
CMH6:15 amColumbus
8h 35m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Oct 20
PTY3:30 pmPanama City Tocumen Intl
18h 29m
1 stop
CMH10:59 amColumbus
$413
Find similar
United Airlines
Oct 8
CMH6:15 amColumbus
8h 59m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Oct 20
PTY3:30 pmPanama City Tocumen Intl
17h 28m
2 stops
CMH9:58 amColumbus
$418
Find similar
United Airlines
Nov 13
CMH6:30 amColumbus
13h 08m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Nov 16
PTY8:55 amPanama City Tocumen Intl
13h 17m
1 stop
CMH10:12 pmColumbus
$430
Find similar

American Airlines flights from Columbus Airport to Panama

Our best American Airlines deals on Columbus Airport to Panama flight tickets
American Airlines
Feb 1
CMH3:57 pmColumbus
21h 13m
2 stops
PTY1:10 pmPanama City Tocumen Intl
Feb 8
PTY2:45 pmPanama City Tocumen Intl
9h 47m
1 stop
CMH12:32 amColumbus
$457
Find similar
American Airlines
Feb 1
CMH12:11 pmColumbus
24h 59m
1 stop
PTY1:10 pmPanama City Tocumen Intl
Feb 8
PTY2:45 pmPanama City Tocumen Intl
9h 47m
1 stop
CMH12:32 amColumbus
$463
Find similar
American Airlines
Nov 24
CMH4:44 pmColumbus
20h 54m
2 stops
PTY1:38 pmPanama City Tocumen Intl
Nov 27
PTY2:43 pmPanama City Tocumen Intl
18h 46m
2 stops
CMH9:29 amColumbus
$468
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 10, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mié. 10/8

6:15 am-1:50 pm

1 stop8h 35m

Panama City Tocumen Intl

lun. 10/20

3:30 pm-10:59 am

1 stop18h 29m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mié. 10/8

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

lun. 10/20

3:30 pm-9:58 am

2 stops17h 28m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jue. 11/13

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

dom. 11/16

8:55 am-10:12 pm

1 stop13h 17m

$430

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

sáb. 10/25

8:45 am-6:37 pm

2 stops10h 52m

Panama City Tocumen Intl

lun. 10/27

3:41 pm-1:21 pm

2 stops20h 40m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

dom. 2/1

3:57 pm-1:10 pm

2 stops21h 13m

Panama City Tocumen Intl

dom. 2/8

2:45 pm-12:32 am

1 stop9h 47m

$457

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

lun. 11/24

6:00 am-2:12 pm

1 stop8h 12m

Panama City Tocumen Intl

jue. 11/27

3:37 pm-12:18 am

1 stop8h 41m

$461

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

dom. 2/1

12:11 pm-1:10 pm

1 stop24h 59m

Panama City Tocumen Intl

dom. 2/8

2:45 pm-12:32 am

1 stop9h 47m

$463

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

vie. 10/24

5:00 am-9:10 pm

2 stops17h 10m

Panama City Tocumen Intl

jue. 10/30

2:55 am-5:16 pm

2 stops13h 21m

$522

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 11/11

6:45 am-1:00 am

2 stops18h 15m

Panama City Tocumen Intl

lun. 11/17

2:55 am-9:12 pm

2 stops18h 17m

$543

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 11/11

7:50 pm-7:25 pm

3 stops23h 35m

Panama City Tocumen Intl

mar. 11/18

1:45 pm-9:49 am

3 stops20h 04m

$895

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Columbus Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Columbus Airport, with most prices found around $477. If you don’t want to visit Panama in October, then you should wait until July to fly from Columbus Airport, when ticket prices are also cheap, with an average price of $511.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Columbus Airport. The lowest ticket price found for a Wednesday departure recently was $483. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Columbus Airport to Panama for around $823.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Columbus Airport to Panama when you can find flight prices for as low as $459. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $568 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Columbus Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $601 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Columbus Airport for as low as $479 on momondo.

Can stopping save me money on Columbus Airport to Panama flights?

You could potentially save up to 27% on your flight if you consider stops on a Columbus Airport to Panama flight.

Cheap Columbus Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Panama

Direct flights

None
There are no direct flights from Columbus Airport to Panama. There are no popular flight routes from Columbus Airport to Panama.
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  • When did momondo last update prices for flights from Columbus Airport to Panama?

    Prices for flights from Columbus Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Columbus Airport to Panama?

  • How old do you have to be to fly from Columbus Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus Airport to Panama

Compare and see reviews for airlines that fly from Columbus Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $393Free CancellationRating
7.9
7,963 reviews
Search Delta flights
United AirlinesPriceFrom $434Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights
American AirlinesPriceFrom $450Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Columbus to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Columbus to Panama with flexible booking policies on momondo?

All flight searches from Columbus to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Columbus to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Columbus.

I’m not ready to book a flight from Columbus to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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