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Cheap flights from Columbus Airport to Panama from $192

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Panama departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:10 am - 2:14 pm
CMH
-
PTY
9h 04m
1 stop
United Airlines Logo
10:55 pm - 10:51 am
PTY
-
CMH
10h 56m
1 stop
$465United Airlines
Wed, Apr 15 - Mon, Apr 20
United Airlines Logo
7:00 am - 6:37 pm
CMH
-
PTY
12h 37m
2 stops
United Airlines Logo
10:55 pm - 10:51 am
PTY
-
CMH
10h 56m
1 stop
$469United Airlines
Wed, Apr 15 - Mon, Apr 20
Delta Logo
7:14 pm - 1:02 pm
CMH
-
PTY
18h 48m
1 stop
Delta Logo
2:28 pm - 11:59 pm
PTY
-
CMH
8h 31m
1 stop
$472Delta
Sun, Apr 26 - Thu, Aug 20
United Airlines Logo
11:39 am - 4:12 pm
CMH
-
PTY
29h 33m
1 stop
United Airlines Logo
3:20 pm - 9:55 am
PTY
-
CMH
17h 35m
2 stops
$479United Airlines
Sun, Apr 26 - Mon, Aug 17
United Airlines Logo
6:10 am - 4:12 pm
CMH
-
PTY
11h 02m
1 stop
United Airlines Logo
3:30 pm - 10:52 am
PTY
-
CMH
18h 22m
1 stop
$482United Airlines
Tue, Apr 28 - Fri, May 1
United Airlines Logo
11:39 am - 4:12 pm
CMH
-
PTY
29h 33m
1 stop
United Airlines Logo
3:20 pm - 9:50 pm
PTY
-
CMH
29h 30m
1 stop
$484United Airlines
Sun, Apr 26 - Mon, Aug 17
United Airlines Logo
2:15 pm - 4:04 am
CMH
-
PTY
14h 49m
2 stops
United Airlines Logo
10:55 pm - 1:14 pm
PTY
-
CMH
13h 19m
2 stops
$486United Airlines
Tue, Apr 28 - Fri, May 1
Delta Logo
5:00 pm - 1:02 pm
CMH
-
PTY
21h 02m
1 stop
Delta Logo
2:28 pm - 11:59 pm
PTY
-
CMH
8h 31m
1 stop
$490Delta
Fri, Apr 24 - Wed, Aug 19
United Airlines Logo
5:01 pm - 4:12 pm
CMH
-
PTY
24h 11m
1 stop
United Airlines Logo
9:45 am - 8:57 pm
PTY
-
CMH
10h 12m
1 stop
$491United Airlines
Mon, Jun 1 - Sat, Jun 6
Delta Logo
7:12 am - 1:02 pm
CMH
-
PTY
6h 50m
1 stop
Delta Logo
2:15 pm - 12:30 am
PTY
-
CMH
9h 15m
1 stop
$499Delta
Fri, May 1 - Fri, May 8

Delta flights from Columbus Airport to Panama

Our best Delta deals on Columbus Airport to Panama flight tickets
Delta
Apr 26
CMH12:49 pmColumbus
25h 13m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Aug 19
PTY2:28 pmPanama City Tocumen Intl
17h 30m
1 stop
CMH8:58 amColumbus
$472
Delta
Apr 24
CMH5:00 pmColumbus
21h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Aug 19
PTY2:28 pmPanama City Tocumen Intl
8h 31m
1 stop
CMH11:59 pmColumbus
$490
Delta
May 1
CMH7:12 amColumbus
6h 50m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 8
PTY2:15 pmPanama City Tocumen Intl
9h 15m
1 stop
CMH12:30 amColumbus
$499

Copa Airlines flights from Columbus Airport to Panama

Our best Copa Airlines deals on Columbus Airport to Panama flight tickets
Copa Airlines
May 22
CMH6:35 amColumbus
13h 56m
1 stop
PTY7:31 pmPanama City Tocumen Intl
May 25
PTY3:30 pmPanama City Tocumen Intl
16h 08m
2 stops
CMH8:38 amColumbus
$534
Copa Airlines
May 22
CMH6:35 amColumbus
13h 56m
1 stop
PTY7:31 pmPanama City Tocumen Intl
May 24
PTY3:30 pmPanama City Tocumen Intl
16h 08m
2 stops
CMH8:38 amColumbus
$551
Copa Airlines
May 22
CMH6:35 amColumbus
13h 56m
1 stop
PTY7:31 pmPanama City Tocumen Intl
May 25
PTY3:30 pmPanama City Tocumen Intl
18h 32m
1 stop
CMH11:02 amColumbus
$573

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

6:10 am-2:14 pm

1 stop9h 04m

Panama City Tocumen Intl

Mon 4/20

10:55 pm-10:51 am

1 stop10h 56m

$465

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

7:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Mon 4/20

10:55 pm-10:51 am

1 stop10h 56m

$469

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/26

7:14 pm-1:02 pm

1 stop18h 48m

Panama City Tocumen Intl

Thu 8/20

2:28 pm-11:59 pm

1 stop8h 31m

$472

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/26

11:39 am-4:12 pm

1 stop29h 33m

Panama City Tocumen Intl

Mon 8/17

3:20 pm-9:55 am

2 stops17h 35m

$479

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 4/28

6:10 am-4:12 pm

1 stop11h 02m

Panama City Tocumen Intl

Fri 5/1

3:30 pm-10:52 am

1 stop18h 22m

$482

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/26

11:39 am-4:12 pm

1 stop29h 33m

Panama City Tocumen Intl

Mon 8/17

3:20 pm-9:50 pm

1 stop29h 30m

$484

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 4/28

2:15 pm-4:04 am

2 stops14h 49m

Panama City Tocumen Intl

Fri 5/1

10:55 pm-1:14 pm

2 stops13h 19m

$486

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 4/24

5:00 pm-1:02 pm

1 stop21h 02m

Panama City Tocumen Intl

Wed 8/19

2:28 pm-11:59 pm

1 stop8h 31m

$490

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 6/1

5:01 pm-4:12 pm

1 stop24h 11m

Panama City Tocumen Intl

Sat 6/6

9:45 am-8:57 pm

1 stop10h 12m

$491

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 5/1

7:12 am-1:02 pm

1 stop6h 50m

Panama City Tocumen Intl

Fri 5/8

2:15 pm-12:30 am

1 stop9h 15m

$499

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Columbus Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of May is, on average, the cheapest month to fly to Panama from Columbus Airport, with most prices found around $478. If you don’t want to visit Panama in May, then you should wait until October to fly from Columbus Airport, when ticket prices are also cheap, with an average price of $480.

Can stopping save me money on Columbus Airport to Panama flights?

You could potentially save up to 35% on your flight if you consider stops on a Columbus Airport to Panama flight.

Cheap Columbus Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Panama

Fastest flight time

7h 57m

Direct flights

None
The fastest flight from Columbus Airport to Panama takes 7h 57m
There are no direct flights from Columbus Airport to Panama. There are no popular flight routes from Columbus Airport to Panama.
Search flight deals

  • When did momondo last update prices for flights from Columbus Airport to Panama?

    Prices for flights from Columbus Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Columbus Airport to Panama?

  • How old do you have to be to fly from Columbus Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus Airport to Panama

Compare and see reviews for airlines that fly from Columbus Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $263Free CancellationRating
7.9
8,239 reviews
Search Delta flights
American AirlinesPriceFrom $413Free CancellationRating
7.2
11,344 reviews
Search American Airlines flights
United AirlinesPriceFrom $413Free CancellationRating
7.4
9,344 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Columbus to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Columbus to Panama with flexible booking policies on momondo?

All flight searches from Columbus to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Columbus to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Columbus.

I’m not ready to book a flight from Columbus to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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