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Cheap flights from Columbus Airport to Panama from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Panama departing on 8/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Columbus Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
6:30 am - 2:14 pm
CMH
-
PTY
8h 44m
1 stop
Copa Airlines Logo
10:00 am - 11:43 pm
PTY
-
CMH
12h 43m
1 stop
$604Copa Airlines
Thu, Aug 20 - Wed, Aug 26
United Airlines Logo
6:05 am - 8:02 pm
CMH
-
PTY
13h 57m
1 stop
United Airlines Logo
8:55 am - 11:58 pm
PTY
-
CMH
15h 03m
3 stops
$605United Airlines
Wed, Nov 11 - Tue, Nov 17
United Airlines Logo
11:37 am - 4:04 am
CMH
-
PTY
17h 27m
1 stop
United Airlines Logo
3:30 pm - 1:06 pm
PTY
-
CMH
20h 36m
2 stops
$609United Airlines
Tue, Aug 11 - Tue, Aug 18
United Airlines Logo
1:00 pm - 8:02 pm
CMH
-
PTY
31h 02m
1 stop
United Airlines Logo
4:41 pm - 10:59 am
PTY
-
CMH
18h 18m
1 stop
$613United Airlines
Tue, Nov 10 - Tue, Nov 17
American Airlines Logo
6:16 am - 12:39 pm
CMH
-
PTY
7h 23m
1 stop
American Airlines Logo
1:39 pm - 5:00 pm
PTY
-
CMH
26h 21m
1 stop
$618American Airlines
Fri, Aug 14 - Tue, Aug 18
Copa Airlines Logo
6:30 am - 2:14 pm
CMH
-
PTY
8h 44m
1 stop
Copa Airlines Logo
10:55 pm - 6:01 pm
PTY
-
CMH
18h 06m
1 stop
$621Copa Airlines
Tue, Aug 4 - Fri, Aug 21
United Airlines Logo
6:05 am - 8:02 pm
CMH
-
PTY
13h 57m
1 stop
United Airlines Logo
8:55 am - 11:34 pm
PTY
-
CMH
14h 39m
1 stop
$622United Airlines
Sun, Nov 8 - Wed, Nov 18
United Airlines Logo
11:03 am - 4:04 am
CMH
-
PTY
18h 01m
2 stops
United Airlines Logo
3:30 pm - 1:06 pm
PTY
-
CMH
20h 36m
2 stops
$626United Airlines
Tue, Aug 4 - Sat, Aug 15
United Airlines Logo
6:11 pm - 4:04 am
CMH
-
PTY
10h 53m
1 stop
United Airlines Logo
3:30 pm - 11:44 pm
PTY
-
CMH
31h 14m
1 stop
$634United Airlines
Tue, Aug 11 - Fri, Aug 21
United Airlines Logo
6:11 pm - 7:31 pm
CMH
-
PTY
26h 20m
1 stop
United Airlines Logo
9:45 am - 1:14 pm
PTY
-
CMH
26h 29m
2 stops
$635United Airlines
Mon, Sep 21 - Fri, Sep 25

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American Airlines flights from Columbus Airport to Panama

Our best American Airlines deals on Columbus Airport to Panama flight tickets
American Airlines
Aug 14
CMH6:16 amColumbus
7h 23m
1 stop
PTY12:39 pmPanama City Tocumen Intl
Aug 18
PTY1:39 pmPanama City Tocumen Intl
26h 21m
1 stop
CMH5:00 pmColumbus
$618
American Airlines
Aug 2
CMH3:44 pmColumbus
21h 30m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Aug 9
PTY1:39 pmPanama City Tocumen Intl
19h 08m
2 stops
CMH9:47 amColumbus
$648
American Airlines
Aug 2
CMH5:08 amColumbus
8h 06m
1 stop
PTY12:14 pmPanama City Tocumen Intl
Aug 9
PTY1:39 pmPanama City Tocumen Intl
19h 08m
2 stops
CMH9:47 amColumbus
$661

United Airlines flights from Columbus Airport to Panama

Our best United Airlines deals on Columbus Airport to Panama flight tickets
United Airlines
Nov 11
CMH6:05 amColumbus
13h 57m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Nov 17
PTY8:55 amPanama City Tocumen Intl
15h 03m
3 stops
CMH11:58 pmColumbus
$605
United Airlines
Aug 11
CMH11:37 amColumbus
17h 27m
1 stop
PTY4:04 amPanama City Tocumen Intl
Aug 18
PTY3:30 pmPanama City Tocumen Intl
20h 36m
2 stops
CMH1:06 pmColumbus
$609
United Airlines
Nov 10
CMH1:00 pmColumbus
31h 02m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Nov 17
PTY4:41 pmPanama City Tocumen Intl
18h 18m
1 stop
CMH10:59 amColumbus
$613

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 8/20

6:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Wed 8/26

10:00 am-11:43 pm

1 stop12h 43m

$604

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 11/11

6:05 am-8:02 pm

1 stop13h 57m

Panama City Tocumen Intl

Tue 11/17

8:55 am-11:58 pm

3 stops15h 03m

$605

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 8/11

11:37 am-4:04 am

1 stop17h 27m

Panama City Tocumen Intl

Tue 8/18

3:30 pm-1:06 pm

2 stops20h 36m

$609

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 11/10

1:00 pm-8:02 pm

1 stop31h 02m

Panama City Tocumen Intl

Tue 11/17

4:41 pm-10:59 am

1 stop18h 18m

$613

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 8/14

6:16 am-12:39 pm

1 stop7h 23m

Panama City Tocumen Intl

Tue 8/18

1:39 pm-5:00 pm

1 stop26h 21m

$618

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 8/4

6:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Fri 8/21

10:55 pm-6:01 pm

1 stop18h 06m

$621

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 11/8

6:05 am-8:02 pm

1 stop13h 57m

Panama City Tocumen Intl

Wed 11/18

8:55 am-11:34 pm

1 stop14h 39m

$622

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 8/4

11:03 am-4:04 am

2 stops18h 01m

Panama City Tocumen Intl

Sat 8/15

3:30 pm-1:06 pm

2 stops20h 36m

$626

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 8/11

6:11 pm-4:04 am

1 stop10h 53m

Panama City Tocumen Intl

Fri 8/21

3:30 pm-11:44 pm

1 stop31h 14m

$634

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 9/21

6:11 pm-7:31 pm

1 stop26h 20m

Panama City Tocumen Intl

Fri 9/25

9:45 am-1:14 pm

2 stops26h 29m

$635

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Columbus Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Columbus Airport, with most prices found around $359. If you don’t want to visit Panama in October, then you should wait until January to fly from Columbus Airport, when ticket prices are also cheap, with an average price of $390.

Can stopping save me money on Columbus Airport to Panama flights?

You could potentially save up to 17% on your flight if you consider stops on a Columbus Airport to Panama flight.

Cheap Columbus Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Panama

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Columbus Airport to Panama takes 7h 55m
There are no direct flights from Columbus Airport to Panama. There are no popular flight routes from Columbus Airport to Panama.
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Frequently asked questions about flying from Columbus Airport to Panama

  • When did momondo last update prices for flights from Columbus Airport to Panama?

    Prices for flights from Columbus Airport to Panama were last updated today.

  • How many operators does momondo search for flights from Columbus Airport to Panama?

  • How old do you have to be to fly from Columbus Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus Airport to Panama

Compare and see reviews for airlines that fly from Columbus Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $413Free CancellationRating
7.8
8,453 reviews
Search Delta flights
American AirlinesPriceFrom $413Free CancellationRating
7.1
11,764 reviews
Search American Airlines flights
United AirlinesPriceFrom $413Free CancellationRating
7.4
9,927 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Columbus to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Columbus to Panama with flexible booking policies on momondo?

All flight searches from Columbus to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Columbus to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Columbus.

I’m not ready to book a flight from Columbus to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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