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Cheap flights from Iowa to Santo Domingo from $306

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Santo Domingo departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Iowa to Santo Domingo

Cheap round-trip flights

Delta Logo
5:44 am - 1:24 pmDSM-SDQ
6h 40m1 stop
Delta Logo
2:50 pm - 10:37 pmSDQ-DSM
8h 47m1 stop
$515Delta
Find Deal
Wed, Sep 24 - Wed, Oct 1
American Airlines Logo
6:58 am - 10:50 pmDSM-SDQ
13h 52m1 stop
American Airlines Logo
8:50 am - 10:25 pmSDQ-DSM
15h 35m1 stop
$517American Airlines
Find Deal
Wed, Feb 4 - Wed, Feb 11
Delta Logo
5:44 am - 1:24 pmDSM-SDQ
6h 40m1 stop
Delta Logo
7:40 pm - 10:40 amSDQ-DSM
16h 00m2 stops
$519Delta
Find Deal
Wed, Sep 24 - Wed, Oct 1
American Airlines Logo
5:10 am - 8:30 pmDSM-SDQ
14h 20m2 stops
American Airlines Logo
7:00 am - 8:21 pmSDQ-DSM
14h 21m2 stops
$521American Airlines
Find Deal
Wed, Sep 24 - Wed, Oct 1
United Airlines Logo
8:00 am - 11:46 pmDSM-SDQ
13h 46m2 stops
United Airlines Logo
6:00 am - 5:33 pmSDQ-DSM
13h 33m2 stops
$522United Airlines
Find Deal
Wed, Feb 4 - Wed, Feb 11
United Airlines Logo
11:35 am - 1:50 amOMA-SDQ
13h 15m2 stops
United Airlines Logo
5:45 am - 8:01 pmSDQ-OMA
15h 16m2 stops
$529United Airlines
Find Deal
Fri, Sep 5 - Fri, Sep 12
Logo
7:15 pm - 11:56 amDSM-SDQ
15h 41m2 stops
Logo
5:05 pm - 8:41 pmSDQ-DSM
28h 36m2 stops
$561
Find Deal
Thu, Aug 21 - Sun, Aug 24
Logo
7:15 pm - 11:56 amDSM-SDQ
15h 41m2 stops
Logo
5:05 pm - 8:41 pmSDQ-DSM
28h 36m3 stops
$597
Find Deal
Thu, Aug 21 - Sun, Aug 24
Avianca Logo
8:00 am - 5:20 pmDSM-SDQ
31h 20m2 stops
Avianca Logo
6:15 pm - 9:36 pmSDQ-DSM
29h 21m2 stops
$1,335Avianca
Find Deal
Thu, Feb 5 - Sun, Feb 8
Avianca Logo
8:00 am - 10:55 amDSM-SDQ
24h 55m2 stops
Avianca Logo
11:50 am - 9:36 pmSDQ-DSM
35h 46m2 stops
$1,365Avianca
Find Deal
Fri, Feb 6 - Mon, Feb 9

American Airlines flights from Iowa to Santo Domingo

Our best American Airlines deals on Iowa to Santo Domingo flight tickets
American Airlines
Feb 4
DSM6:58 amDes Moines
13h 52m
1 stop
SDQ10:50 pmSanto Domingo Las Americas
Feb 11
SDQ8:50 amSanto Domingo Las Americas
15h 35m
1 stop
DSM10:25 pmDes Moines
$517
Find similar
American Airlines
Sep 24
DSM5:10 amDes Moines
14h 20m
2 stops
SDQ8:30 pmSanto Domingo Las Americas
Oct 1
SDQ7:00 amSanto Domingo Las Americas
14h 21m
2 stops
DSM8:21 pmDes Moines
$521
Find similar
American Airlines
Dec 11
OMA6:09 pmOmaha Eppley Airfield
17h 36m
2 stops
SDQ1:45 pmSanto Domingo Las Americas
Dec 15
SDQ5:50 pmSanto Domingo Las Americas
16h 56m
2 stops
OMA8:46 amOmaha Eppley Airfield
$542
Find similar

United Airlines flights from Iowa to Santo Domingo

Our best United Airlines deals on Iowa to Santo Domingo flight tickets
United Airlines
Feb 4
DSM8:00 amDes Moines
13h 46m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 11
SDQ6:00 amSanto Domingo Las Americas
13h 33m
2 stops
DSM5:33 pmDes Moines
$522
Find similar
United Airlines
Sep 5
OMA11:35 amOmaha Eppley Airfield
13h 15m
2 stops
SDQ1:50 amSanto Domingo Las Americas
Sep 12
SDQ5:45 amSanto Domingo Las Americas
15h 16m
2 stops
OMA8:01 pmOmaha Eppley Airfield
$529
Find similar
United Airlines
Sep 24
DSM1:10 pmDes Moines
11h 40m
2 stops
SDQ1:50 amSanto Domingo Las Americas
Oct 1
SDQ5:45 amSanto Domingo Las Americas
14h 34m
2 stops
DSM7:19 pmDes Moines
$639
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2025.
Use the filters below to find and compare flights from Iowa to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Wed 9/24

5:44 am-1:24 pm

1 stop6h 40m

Santo Domingo Las Americas

Wed 10/1

2:50 pm-10:37 pm

1 stop8h 47m

$515

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Wed 2/4

6:58 am-10:50 pm

1 stop13h 52m

Santo Domingo Las Americas

Wed 2/11

8:50 am-10:25 pm

1 stop15h 35m

$517

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Wed 9/24

5:44 am-1:24 pm

1 stop6h 40m

Santo Domingo Las Americas

Wed 10/1

7:40 pm-10:40 am

2 stops16h 00m

$519

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Wed 9/24

5:10 am-8:30 pm

2 stops14h 20m

Santo Domingo Las Americas

Wed 10/1

7:00 am-8:21 pm

2 stops14h 21m

$521

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Wed 2/4

8:00 am-11:46 pm

2 stops13h 46m

Santo Domingo Las Americas

Wed 2/11

6:00 am-5:33 pm

2 stops13h 33m

$522

OmahaSanto Domingo

OMA - SDQ

OMASDQ

Omaha Eppley Airfield

Fri 9/5

11:35 am-1:50 am

2 stops13h 15m

Santo Domingo Las Americas

Fri 9/12

5:45 am-8:01 pm

2 stops15h 16m

$529

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Thu 8/21

7:15 pm-11:56 am

2 stops15h 41m

Santo Domingo Las Americas

Sun 8/24

5:05 pm-8:41 pm

2 stops28h 36m

$561

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Thu 8/21

7:15 pm-11:56 am

2 stops15h 41m

Santo Domingo Las Americas

Sun 8/24

5:05 pm-8:41 pm

3 stops28h 36m

$597

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Thu 2/5

8:00 am-5:20 pm

2 stops31h 20m

Santo Domingo Las Americas

Sun 2/8

6:15 pm-9:36 pm

2 stops29h 21m

$1,335

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Fri 2/6

8:00 am-10:55 am

2 stops24h 55m

Santo Domingo Las Americas

Mon 2/9

11:50 am-9:36 pm

2 stops35h 46m

$1,365

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Iowa to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Tuesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $613. The most expensive day to fly to Santo Domingo is Friday, with ticket prices averaging around $823.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $674. Try not to purchase tickets in the morning because they tend to be around $690. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Iowa to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Santo Domingo

Best Price Found

$306

Fastest flight time

6h 30m

Direct flights

None

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Iowa in the past 72 hours is $306. The best round-trip flight deal from Iowa to Santo Domingo found on momondo in the last 72 hours is $515.
The fastest flight from Iowa to Santo Domingo takes 6h 30m
There are no direct flights from Iowa to Santo Domingo. Popular non-direct routes for this connection are Des Moines Airport - Santo Domingo Las Americas Airport and Omaha Eppley Airfield Airport - Santo Domingo Las Americas Airport.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
Search flight deals

  • When did momondo last update prices for flights from Iowa to Santo Domingo Las Americas Airport?

    Prices for flights from Iowa to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Iowa to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to Santo Domingo

Compare and see reviews for airlines that fly from Iowa to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $524Free CancellationRating
8.0
7,979 reviews
Search Delta flights
American AirlinesPriceFrom $529Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Iowa with this policy.

How can momondo help me find flights from Iowa to Santo Domingo?

momondo helps you find the best flight between Iowa and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Iowa. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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