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Cheap flights from Indianapolis to Santo Domingo from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Santo Domingo departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Indianapolis to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:26 pm - 2:27 pm
IND
-
SDQ
17h 01m1 stop
Multiple Airlines Logo
12:31 pm - 5:25 pm
SDQ
-
IND
29h 54m1 stop
$321Multiple Airlines
Thu, Feb 5 - Thu, Feb 12
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$354Spirit Airlines
Wed, Jan 14 - Wed, Jan 21
Multiple Airlines Logo
5:10 am - 3:27 pm
IND
-
SDQ
33h 17m2 stops
Multiple Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$360Multiple Airlines
Wed, Jan 14 - Wed, Jan 21
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$367Spirit Airlines
Sun, Jan 11 - Wed, Jan 28
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$371Spirit Airlines
Sun, Jan 11 - Wed, Jan 28
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$375Spirit Airlines
Tue, Feb 3 - Fri, Feb 13
Spirit Airlines Logo
8:26 pm - 2:27 pm
IND
-
SDQ
17h 01m1 stop
Spirit Airlines Logo
3:32 pm - 8:32 am
SDQ
-
IND
18h 00m2 stops
$376Spirit Airlines
Thu, Feb 5 - Thu, Feb 12
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$377Spirit Airlines
Tue, Feb 3 - Fri, Feb 13
Spirit Airlines Logo
5:10 am - 2:27 pm
IND
-
SDQ
8h 17m1 stop
Spirit Airlines Logo
3:32 pm - 9:43 am
SDQ
-
IND
19h 11m2 stops
$384Spirit Airlines
Sun, Jan 11 - Wed, Jan 28
Multiple Airlines Logo
5:07 pm - 10:01 am
IND
-
SDQ
15h 54m1 stop
Multiple Airlines Logo
3:32 pm - 10:48 pm
SDQ
-
IND
8h 16m1 stop
$389Multiple Airlines
Fri, Jan 2 - Fri, Jan 30

Spirit Airlines flights from Indianapolis to Santo Domingo

Our best Spirit Airlines deals on Indianapolis to Santo Domingo flight tickets
Spirit Airlines
Jan 14
IND5:10 amIndianapolis
8h 17m
1 stop
SDQ2:27 pmSanto Domingo Las Americas
Jan 21
SDQ3:32 pmSanto Domingo Las Americas
8h 16m
1 stop
IND10:48 pmIndianapolis
$354
Find similar
Spirit Airlines
Jan 11
IND5:10 amIndianapolis
8h 17m
1 stop
SDQ2:27 pmSanto Domingo Las Americas
Jan 28
SDQ3:32 pmSanto Domingo Las Americas
8h 16m
1 stop
IND10:48 pmIndianapolis
$367
Find similar
Spirit Airlines
Jan 11
IND5:10 amIndianapolis
8h 17m
1 stop
SDQ2:27 pmSanto Domingo Las Americas
Jan 28
SDQ3:32 pmSanto Domingo Las Americas
8h 16m
1 stop
IND10:48 pmIndianapolis
$371
Find similar

American Airlines flights from Indianapolis to Santo Domingo

Our best American Airlines deals on Indianapolis to Santo Domingo flight tickets
American Airlines
Mar 12
IND7:23 pmIndianapolis
13h 37m
1 stop
SDQ9:00 amSanto Domingo Las Americas
Mar 18
SDQ6:00 amSanto Domingo Las Americas
12h 32m
1 stop
IND6:32 pmIndianapolis
$518
Find similar
American Airlines
Mar 6
IND7:09 pmIndianapolis
13h 39m
1 stop
SDQ9:48 amSanto Domingo Las Americas
Mar 15
SDQ5:52 pmSanto Domingo Las Americas
16h 16m
1 stop
IND10:08 amIndianapolis
$543
Find similar
American Airlines
Jan 2
IND6:03 amIndianapolis
10h 48m
2 stops
SDQ5:51 pmSanto Domingo Las Americas
Jan 30
SDQ1:23 pmSanto Domingo Las Americas
11h 04m
2 stops
IND11:27 pmIndianapolis
$547
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Indianapolis to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Thu 2/5

8:26 pm-2:27 pm

1 stop17h 01m

Santo Domingo Las Americas

Thu 2/12

12:31 pm-5:25 pm

1 stop29h 54m

$321

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Wed 1/14

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Wed 1/21

3:32 pm-10:48 pm

1 stop8h 16m

$354

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Wed 1/14

5:10 am-3:27 pm

2 stops33h 17m

Santo Domingo Las Americas

Wed 1/21

3:32 pm-10:48 pm

1 stop8h 16m

$360

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Sun 1/11

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Wed 1/28

3:32 pm-10:48 pm

1 stop8h 16m

$367

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Sun 1/11

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Wed 1/28

3:32 pm-10:48 pm

1 stop8h 16m

$371

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Tue 2/3

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Fri 2/13

3:32 pm-10:48 pm

1 stop8h 16m

$375

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Thu 2/5

8:26 pm-2:27 pm

1 stop17h 01m

Santo Domingo Las Americas

Thu 2/12

3:32 pm-8:32 am

2 stops18h 00m

$376

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Tue 2/3

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Fri 2/13

3:32 pm-10:48 pm

1 stop8h 16m

$377

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Sun 1/11

5:10 am-2:27 pm

1 stop8h 17m

Santo Domingo Las Americas

Wed 1/28

3:32 pm-9:43 am

2 stops19h 11m

$384

IndianapolisSanto Domingo

IND - SDQ

INDSDQ

Indianapolis

Fri 1/2

5:07 pm-10:01 am

1 stop15h 54m

Santo Domingo Las Americas

Fri 1/30

3:32 pm-10:48 pm

1 stop8h 16m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Indianapolis to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in January, then you should wait until September to fly from Indianapolis, when ticket prices are also cheap, with an average price of $524.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Saturday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $429. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $630.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $366. Try not to purchase tickets in the morning because they tend to be around $551. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Indianapolis for as low as $450 on momondo.

Can stopping save me money on Indianapolis to Santo Domingo flights?

You could potentially save up to 42% on your flight if you consider stops on a Indianapolis to Santo Domingo flight.

How have Indianapolis to Santo Domingo flight prices changed over time?

As of December 2025, prices for Indianapolis to Santo Domingo flights are approximately 51% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Santo Domingo (IND to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Santo Domingo

Fastest flight time

7h 10m

Direct flights

None
The fastest flight from Indianapolis to Santo Domingo takes 7h 10m
There are no direct flights from Indianapolis to Santo Domingo. There are no popular flight routes from Indianapolis to Santo Domingo.
Search flight deals

  • How far is Indianapolis to Santo Domingo Las Americas by plane?

    A flight from Indianapolis to Santo Domingo Las Americas will travel around 1759.1 mi. Flights usually cover this in 7h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Indianapolis Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Indianapolis Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Indianapolis Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Indianapolis to Santo Domingo?

Best airlines flying from Indianapolis to Santo Domingo

Compare and see reviews for airlines that fly from Indianapolis to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $271Free CancellationRating
6.3
8,196 reviews
Search Spirit Airlines flights
DeltaPriceFrom $491Free CancellationRating
7.9
8,014 reviews
Search Delta flights
American AirlinesPriceFrom $514Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Santo Domingo?

Finding the right flight to Santo Domingo from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Indianapolis to Santo Domingo with flexible booking policies on momondo?

Flights from Indianapolis to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Indianapolis to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Indianapolis.

I’m not ready to book a flight from Indianapolis to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Indianapolis to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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