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Cheap flights from Indianapolis to Santiago from $378

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Santiago departing on 3/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Indianapolis to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:57 pm - 6:55 amIND-SCL
15h 58m1 stop
Delta Logo
11:10 pm - 12:29 amSCL-IND
27h 19m1 stop
$749Delta
Find Deal
mié., dic. 10 - jue., dic. 18
Multiple Airlines Logo
10:38 am - 2:40 pmIND-SCL
26h 02m3 stops
Multiple Airlines Logo
12:35 pm - 7:23 pmSCL-IND
32h 48m2 stops
$750Multiple Airlines
Find Deal
jue., ene. 8 - jue., ene. 15
American Airlines Logo
2:56 pm - 8:55 amIND-SCL
15h 59m2 stops
American Airlines Logo
10:30 pm - 12:11 pmSCL-IND
15h 41m2 stops
$752American Airlines
Find Deal
mar., dic. 9 - mar., dic. 16
Delta Logo
12:57 pm - 6:55 amIND-SCL
15h 58m1 stop
Delta Logo
9:30 pm - 1:24 pmSCL-IND
17h 54m1 stop
$754Delta
Find Deal
mar., dic. 9 - lun., dic. 15
Delta Logo
11:33 am - 5:35 amIND-SCL
16h 02m2 stops
Delta Logo
11:25 pm - 1:24 pmSCL-IND
15h 59m2 stops
$755Delta
Find Deal
jue., dic. 11 - lun., dic. 15
Delta Logo
11:33 am - 5:35 amIND-SCL
16h 02m2 stops
Delta Logo
11:25 pm - 1:23 pmSCL-IND
15h 58m2 stops
$756Delta
Find Deal
jue., dic. 11 - mié., dic. 17
Delta Logo
10:09 am - 5:35 amIND-SCL
17h 26m2 stops
Delta Logo
9:30 pm - 1:24 pmSCL-IND
17h 54m1 stop
$757Delta
Find Deal
jue., dic. 11 - lun., dic. 15
Delta Logo
6:00 am - 6:10 amIND-SCL
22h 10m1 stop
Delta Logo
11:10 pm - 10:28 amSCL-IND
13h 18m1 stop
$760Delta
Find Deal
jue., dic. 11 - lun., dic. 15
LATAM Airlines Logo
11:33 am - 2:30 pmIND-SCL
24h 57m3 stops
LATAM Airlines Logo
8:15 am - 12:26 amSCL-IND
18h 11m2 stops
$762LATAM Airlines
Find Deal
mar., dic. 9 - mar., dic. 16
LATAM Airlines Logo
7:00 am - 6:35 amIND-SCL
21h 35m2 stops
LATAM Airlines Logo
5:15 am - 12:26 amSCL-IND
21h 11m2 stops
$763LATAM Airlines
Find Deal
mié., dic. 10 - mar., dic. 16

Delta flights from Indianapolis to Santiago

Our best Delta deals on Indianapolis to Santiago flight tickets
Delta
Dec 10
IND7:00 amIndianapolis
21h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Dec 18
SCL11:25 pmSantiago Arturo Merino Benitez
19h 05m
2 stops
IND4:30 pmIndianapolis
$749
Find similar
Delta
Dec 9
IND12:57 pmIndianapolis
15h 58m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Dec 15
SCL9:30 pmSantiago Arturo Merino Benitez
17h 54m
1 stop
IND1:24 pmIndianapolis
$754
Find similar
Delta
Dec 8
IND11:33 amIndianapolis
17h 27m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Dec 17
SCL9:30 pmSantiago Arturo Merino Benitez
13h 33m
1 stop
IND9:03 amIndianapolis
$755
Find similar

LATAM Airlines flights from Indianapolis to Santiago

Our best LATAM Airlines deals on Indianapolis to Santiago flight tickets
LATAM Airlines
Dec 9
IND12:57 pmIndianapolis
15h 58m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Dec 16
SCL11:10 pmSantiago Arturo Merino Benitez
13h 18m
1 stop
IND10:28 amIndianapolis
$751
Find similar
LATAM Airlines
Dec 9
IND11:33 amIndianapolis
24h 57m
3 stops
SCL2:30 pmSantiago Arturo Merino Benitez
Dec 16
SCL8:15 amSantiago Arturo Merino Benitez
18h 11m
2 stops
IND12:26 amIndianapolis
$762
Find similar
LATAM Airlines
Dec 10
IND5:27 pmIndianapolis
26h 28m
2 stops
SCL9:55 pmSantiago Arturo Merino Benitez
Dec 16
SCL8:15 amSantiago Arturo Merino Benitez
18h 11m
2 stops
IND12:26 amIndianapolis
$763
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 25, 2025.
Use the filters below to find and compare flights from Indianapolis to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mié. 12/10

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

jue. 12/18

11:10 pm-12:29 am

1 stop27h 19m

$749

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 1/8

10:38 am-2:40 pm

3 stops26h 02m

Santiago Arturo Merino Benitez

jue. 1/15

12:35 pm-7:23 pm

2 stops32h 48m

$750

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 12/9

2:56 pm-8:55 am

2 stops15h 59m

Santiago Arturo Merino Benitez

mar. 12/16

10:30 pm-12:11 pm

2 stops15h 41m

$752

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 12/9

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

lun. 12/15

9:30 pm-1:24 pm

1 stop17h 54m

$754

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 12/11

11:33 am-5:35 am

2 stops16h 02m

Santiago Arturo Merino Benitez

lun. 12/15

11:25 pm-1:24 pm

2 stops15h 59m

$755

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 12/11

11:33 am-5:35 am

2 stops16h 02m

Santiago Arturo Merino Benitez

mié. 12/17

11:25 pm-1:23 pm

2 stops15h 58m

$756

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 12/11

10:09 am-5:35 am

2 stops17h 26m

Santiago Arturo Merino Benitez

lun. 12/15

9:30 pm-1:24 pm

1 stop17h 54m

$757

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 12/11

6:00 am-6:10 am

1 stop22h 10m

Santiago Arturo Merino Benitez

lun. 12/15

11:10 pm-10:28 am

1 stop13h 18m

$760

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 12/9

11:33 am-2:30 pm

3 stops24h 57m

Santiago Arturo Merino Benitez

mar. 12/16

8:15 am-12:26 am

2 stops18h 11m

$762

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mié. 12/10

7:00 am-6:35 am

2 stops21h 35m

Santiago Arturo Merino Benitez

mar. 12/16

5:15 am-12:26 am

2 stops21h 11m

$763

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Indianapolis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and Santiago?

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Indianapolis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $847. If you don’t want to visit Santiago in October, then you should wait until February to fly from Indianapolis, when ticket prices are also cheap, with an average price of $848.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Thursday when prices can be found for as low as $834. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,283.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Indianapolis to Santiago when you can find flight prices for as low as $772. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $972 per ticket.

When to book flights from Indianapolis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Santiago (IND to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Santiago

Fastest flight time

17h 12m

Direct flights

None
The fastest flight from Indianapolis to Santiago takes 17h 12m
There are no direct flights from Indianapolis to Santiago. There are no popular flight routes from Indianapolis to Santiago.
Search flight deals

  • How far is Indianapolis to Santiago Arturo Merino Benitez by plane?

    Indianapolis and Santiago Arturo Merino Benitez are 5151.3 mi apart from one another. By plane, this route typically takes 12h 06m.

  • When did momondo last update prices for flights from Indianapolis Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Indianapolis Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Indianapolis Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Indianapolis to Santiago?

Best airlines flying from Indianapolis to Santiago

Compare and see reviews for airlines that fly from Indianapolis to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $693Free CancellationRating
7.9
7,998 reviews
Search Delta flights
LATAM AirlinesPriceFrom $811Free CancellationRating
7.5
1,887 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $864Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Indianapolis to Santiago for you.

Can I find flights from Indianapolis to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Indianapolis with this policy.

How can momondo help me find flights from Indianapolis to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indianapolis to Santiago.

I’m not ready to book a flight from Indianapolis to Santiago right now. Can momondo alert me if prices change?

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